A web based Master calendar of events

Master Calendar of Events is a PHP/MS-SQL application that provides a user-friendly interface to display a listing of campus events via an Internet browser and was specifically designed to display events at the San Bernardino Community College District, Crafton Hills Community College, and San Bernardino Valley College. The application also provides an editor interface that allows designated users to add, edit, or delete events as well as manipulate logos or images

Los Fondos Revolventes Comunales (FRC) impulsado por la Asociación para la Diversificación y el Desarrollo Agrícola Comunal (ADDAC) como alternativa de Desarrollo de las comunidades de San Benito, Waslala Arriba y el Papayo en el municipio de Waslala, Durante el año 2013

La investigación se realizó con la institución de ADDAC, quienes trabajan con 80 fondos revolventes distribuidos en los municipios de Matagalpa, bajo sus criterios la muestra fue intencional, analizando si los FRC de San Benito, Waslala Arriba y el Papayo del municipio de Waslala, son una alternativa al desarrollo humano y comunitario de los usuarios. El método utilizado es la investigación acción participativa, porque da protagonismo a los participantes y de igual manera a los investigadores, agregando que es de tipo descriptiva y explicativa, dado que se describirá el funcionamiento de los fondos, como su influencia en la vida de los usuarios y familias. Con un enfoque cualitativo y cuantitativo, los instrumentos utilizados fueron: grupo focal, entrevista y test de autoestima. Los FRC son una iniciativa para reducir el asistencialismo y lograr integrarse en las zonas rurales, con el propósito de organizar a los productores. El interés de ADDAC es evaluar cómo están realizando los trabajo de campo y así mejorar en las tomas de decisiones en relación a los Fondos. En la primera fase se realizó un diagnóstico participativo, en el que describe la importancia y su contribución al desarrollo humano y comunitario; la segunda fase fue una devolución reflexiva y sistematización con el objetivo de encontrar los factores de éxitos y fracasos, por último realizamos un taller de intervención, para mejorar sus funcionamientos y ser protagonista de cambio en la investigación. Se concluye que los fondos son una alternativa al desarrollo, siempre que estos sean bien manejados y de modo que se explique bien los roles y como deben de funciona

Bleeding tendency in dual antiplatelet therapy with aspirin/clopidogrel: rescue of the template bleeding time in a single-center prospective study

<p>Abstract</p> <p>Background</p> <p>Patients with heightened platelet reactivity in response to antiplatelet agents are at an increased risk of recurrent ischemic events. However, there is a lack of diagnostic criteria for increased response to combined aspirin/clopidogrel therapy. The challenge is to identify patients at risk of bleeding. This study sought to characterize bleeding tendency in patients treated with aspirin and clopidogrel.</p> <p>Patients/methods</p> <p>In a single-center prospective study, 100 patients under long-term aspirin/clopidogrel treatment, the effect of therapy was assayed by template bleeding time (BT) and the inhibition of platelet aggregation (IPA) by light transmission aggregometry (LTA). Arachidonic acid (0.625 mmol/L) and adenosine diphosphate (ADP; 2, 4, and 8 μmol/L) were used as platelet agonists.</p> <p>Results</p> <p>Bleeding episodes (28 nuisance, 2 hematuria [1 severe], 1 severe proctorrhagia, 1 severe epistaxis) were significantly more frequent in patients with longer BT. Template BT ≥ 24 min was associated with bleeding episodes (28 of 32). Risk of bleeding increased 17.4% for each 1 min increase in BT. Correlation was found between BT and IPAmax in response to ADP 2 μmol/L but not to ADP 4 or 8 μmol/L.</p> <p>Conclusion</p> <p>In patients treated with dual aspirin/clopidogrel therapy, nuisance and internal bleeding were significantly associated with template BT and with IPAmax in response to ADP 2 μmol/L but not in response to ADP 4 μmol/L or 8 μmol/L.</p

Fundamentos de la Responsabilidad Penal de la Empresa como nuevo sujeto Activo del Delito

In this article I present from the dogmatic-doctrinal analysis, the criminal responsibility of companies as a new active subject of crime, which has had a profound rejection by a strong doctrinal sector, but that has gradually been consolidated and more in the special part of the penal codes. This responsibility has been raised by the doctrine from two points or from two models of responsibility, each with its characteristics and with their respective criticisms, this responsibility is or was more common in the Anglo-Saxon countries, but as globalization entered business activity carried out in huge economic emporiums, it was representing a risk and a danger for society and for since a few years ago European continental law began its legal regu­lation from criminal law.El artículo presenta desde el análisis dogmático-doctrinario, la responsabilidad penal de la empresa como nuevo sujeto activo del delito, el cual ha tenido un profundo rechazo por un sector doctrinal fuerte, pero que poco a poco se ha ido consolidando y más en la parte especial de los códigos penales, esta res­ponsabilidad, la doctrina la ha planteado desde dos puntos o desde dos modelos de responsabilidad, cada uno con sus características y con sus respectivas críticas, esta responsabilidad es o era más común en los países anglosajones, pero a medida que entro la globalización la actividad empresarial llevada a cabo en enormes emporios económicos fue representando un riesgo y un peligro para la sociedad y desde hace unos años el derecho continental europeo comenzó su regulación legal desde el derecho penal

Gestión pedagógica e innovación educativa en docentes de una institución educativa, Comas, Lima, 2023

El siguiente trabajo de investigación planteó el objetivo de determinar la influencia de la gestión pedagógica sobre la innovación educativa de docentes de una institución educativa pública, Comas, Lima, 2023. Para ello, se utilizó la metodología aplicada, con el enfoque cuantitativo, usando el método hipotéticodeductivo, a nivel explicativo y con un diseño no experimental correlacional. Para el análisis se contó con una población se basó en 80 docentes, quienes fueron consultados en su totalidad con los cuestionarios. Para la recolección de datos se utilizó una encuesta, para lo cual se adoptaron dos cuestionarios con el fin de medir las dos variables. Los mencionados instrumentos, se llegaron a validar por tres expertos los que certificaron que poseen la validez necesaria para su aplicación. De la misma manera, para precisar la confiabilidad se recurrió a la prueba de alfa de Cronbach. Respecto a los datos obtenidos, se analizaron con la regresión logística ordinal, en la que la significancia del informe fue de 0,000. Estos valores permitieron aseverar que la gestión pedagógica afecta significativamente a la innovación educativa, dentro de tres de sus dimensiones consideradas. Solo la relacionada a la función de los estudiantes no obtuvo la correlación positiva, siendo rechazada esa hipótesis

¿El determinismo implica caos en variables hidrologicas?

En este artículo presentamos varias series de tiempo hidrológicas de Argentina que incluyen, evapotranspiración, precipitación y caudales. Revisamos previos resultados y aplicamos el test 0-1 de caos para clasificar las secuencias como regulares o caóticas. Estudios previos han demostrado evidencia de caos en muchos fenómenos hidrológicos usando el método tradicional de la reconstrucción del espacio de fase y el cálculo de exponentes de Lyapunov. El test 0-1 de caos puede ser usado como un primer paso para identificar el tipo de serie de tiempo, y que luego puede ser sujeta al análisis más detallado de la reconstrucción del espacio de fase. Si asumimos que los sistemas que generaron estas series de tiempo son determinísticos, el test 0-1 de caos las clasifica a todas ellas como caóticas.In this paper we present several hydrological time series from Argentina that include, evapotranspiration, precipitation, and stream flow. We survey previous results and apply the 0-1 test for chaos to classify the sequences as regular or chaotic. Previous studies have shown evidence of chaos in several observables from hydrology using the traditional phase space reconstruction method and the computation of Lyapunov exponents. The 0-1 test for chaos can be used as a first step to identify the type of time series, that later can be subjected to the more detailed analysis of the phase space reconstruction. Assuming that the systems that generated these time series are deterministic, the 0-1 test for chaos classifies all of them as chaotic.Fil: Marotta, Sebastian Manuel. Comisión de Investigaciones Científicas de la Provincia de Buenos Aires. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff". - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff". - Universidad Nacional del Centro de la Provincia de Buenos Aires. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff"; Argentina. Universidad Argentina de la Empresa. Facultad de Ingeniería y Ciencias Exactas. Instituto de Tecnología; ArgentinaFil: Rivas, Raul. Comisión de Investigaciones Científicas de la Provincia de Buenos Aires. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff". - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff". - Universidad Nacional del Centro de la Provincia de Buenos Aires. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff"; ArgentinaFil: Guevara Ochoa, Cristian. Comisión de Investigaciones Científicas de la Provincia de Buenos Aires. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff". - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff". - Universidad Nacional del Centro de la Provincia de Buenos Aires. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff"; ArgentinaFil: Degano, María Florencia. Comisión de Investigaciones Científicas de la Provincia de Buenos Aires. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff". - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff". - Universidad Nacional del Centro de la Provincia de Buenos Aires. Instituto de Hidrología de Llanuras "Dr. Eduardo Jorge Usunoff"; Argentin

Chickpea rhizobia symbiosis genes are highly conserved across multiple Mesorhizobium species

ABSTRACT Chickpea has been considered as a restrictive host for nodulation by rhizobia. However, recent studies have reported that several Mesorhizobium species may effectively nodulate chickpea. With the purpose of investigating the evolutionary relationships between these different species with the ability of nodulating the same host, we analysed 21 Portuguese chickpea rhizobial isolates. Symbiosis genes nifH and nodC were sequenced and used for phylogenetic studies. Symbiotic effectiveness was determined to evaluate its relationship with symbiosis genes. The comparison of 16S rRNA gene-based phylogeny with the phylogenies based on symbiosis genes revealed evidence of lateral transfer of symbiosis genes across different species. Chickpea is confirmed as a nonpromiscuous host. Although chickpea is nodulated by many different species, they share common symbiosis genes, suggesting recognition of only a few Nod factors by chickpea. Our results suggest that sequencing of nifH or nodC genes can be used for rapid detection of chickpea mesorhizobia

Pulmonary metastasectomy in colorectal cancer: a prospective study of demography and clinical characteristics of 543 patients in the Spanish colorectal metastasectomy registry (GECMP-CCR)

Objectives: To capture an accurate contemporary description of the practice of pulmonary metastasectomy for colorectal carcinoma in one national healthcare system. Design: A national registry set up in Spain by Grupo Español de Cirugía Metástasis Pulmonares de Carcinoma Colo-Rectal (GECMP-CCR). Setting: 32 Spanish thoracic units. Participants: All patients with one or more histologically proven lung metastasis removed by surgery between March 2008 and February 2010. Interventions: Pulmonary metastasectomy for one or more pulmonary nodules proven to be metastatic colorectal carcinoma. Primary and secondary outcome measures: The age and sex of the patients having this surgery were recorded with the number of metastases removed, the interval between the primary colorectal cancer operation and the pulmonary metastasectomy, and the carcinoembryonic antigen level. Also recorded were the practices with respect to mediastinal lymphadenopathy and coexisting liver metastases. Results: Data were available on 543 patients from 32 units (6-43/unit). They were aged 32-88 (mean 65) years, and 65% were men. In 55% of patients, there was a solitary metastasis. The median interval between the primary cancer resection and metastasectomy was 28 months and the serum carcinoembryonic antigen was low/normal in the majority. Liver metastatic disease was present in 29% of patients at some point prior to pulmonary metastasectomy. Mediastinal lymphadenectomy varied from 9% to 100% of patients. Conclusions: The data represent a prospective comprehensive national data collection on pulmonary metastasectomy. The practice is more conservative than the impression gained when members of the European Society of Thoracic Surgeons were surveyed in 2006/2007 but is more inclusive than would be recommended on the basis of recent outcome analyses. Furtheranalyses on the morbidity associated with this surgery and the correlation between imaging studies and pathological findings are being published separately by GECMP-CCR

Occluded cobalt species over ZSM-5 matrix: Design, preparation, characterization and magnetic behavior

Co-containing molecular sieves with MFI structure was synthesized by the hydrothermal crystallization method and cobalt was incorporated in it by wet impregnation at different percentages. Thermal post-treatments were applied to Co-ZSM-5: calcination and reduction. X ray diffraction (XRD) and FTIR studies confirmed crystallinity, structure and orthorhombic symmetry of the obtained samples (Co-ZSM-5 calcined and Co-ZSM-5 reduced). The XRD, Raman spectroscopy, SEM and TPR techniques for the calcined samples showed the presence of Co3O4 which diminished in the reduced samples and Co0 appeared. The magnetic behavior of the materials was evaluated by magnetization (M) variation with applied magnetic field (H) at different temperatures. Low magnetization is observed in the calcined samples while high values are ttained in the reduced samples, due to the presence of metallic Co.Fil: Pierella, Liliana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Tecnología Química. Universidad Tecnológica Nacional. Facultad Regional Córdoba. Centro de Investigación y Tecnología Química; ArgentinaFil: Saux, Clara. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Tecnología Química. Universidad Tecnológica Nacional. Facultad Regional Córdoba. Centro de Investigación y Tecnología Química; ArgentinaFil: Bertorello, Hector Raul. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; ArgentinaFil: Bercoff, Paula Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; ArgentinaFil: Botta, Pablo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina. Universidad de Santiago de Compostela; EspañaFil: Rivas, Jose. Universidad de Santiago de Compostela; Españ

Disease Phenotype and Outcome Depending on the Age at Disease Onset in Patients Carrying the R92Q Low-Penetrance Variant in TNFRSF1A Gene

Aparició en l'adult; Malalties autoinflamatòries; Variants de baixa penetrànciaAparición en el adulto; Enfermedades autoinflamatorias; Variantes de baja penetranciaAdult onset; Autoinflammatory diseases; Low-penetrance variantsBackground: Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an autosomal-dominant autoinflammatory disease caused by mutations in the TNFRSF1A gene. R92Q, a low-penetrance variant, is usually associated with a milder TRAPS phenotype than structural or pathogenic mutations. No studies differentiating R92Q-related disease in patients with pediatric and adult onset have been performed to date. Objective: To analyze clinical features and disease outcomes in patients diagnosed with TRAPS associated with R92Q variant and to investigate differences between patients with pediatric and adult disease onset. Methods: A retrospective review of patients with R92Q-related disease from four reference centers for autoinflammatory diseases was performed. Clinical and laboratory features, family history of autoinflammatory diseases, treatments received, and outcomes during follow-up were recorded and separately analyzed in pediatric and adult patients. Our results were included in the analysis with other reported pediatric and adult R92Q-related disease series. Results: Our series encompassed 18 patients (9 females and 9 males) with R92Q variant. In 61% of patients, disease onset occurred during infancy and in 39%, during adulthood, with a median diagnostic delay of 5 years and a follow-up of 5.4 years. A positive family history of autoinflammatory disease was detected in 28% of patients. All patients presented with febrile recurrent episodes. Other common symptoms included arthralgia/arthritis (61%), myalgia (39%), asthenia/fatigue (44%), abdominal pain (39%), headache (33%), odynophagia (33%), skin rash (28%), and chest pain (22%). During attacks, 80% of patients increased acute phase reactants levels. No patient had developed amyloidosis during the study period. At the end of follow-up, 28% of patients were asymptomatic and treatment free, 50% were receiving non-steroidal anti-inflammatory drugs or glucocorticoids on demand, and 22% were being treated with biologic agents. When differences between pediatric and adult patients were globally analyzed, adults tended to have longer attacks duration and presented more frequently with chest pain and headache, while abdominal pain, vomiting, cervical adenitis, and pharyngitis predominated in pediatric patients. No differences in outcomes and treatment requirements were observed in both age groups. Conclusion: This study has contributed to characterize R92Q-related disease by identifying trends in disease phenotypes depending on the age at disease onset.This study has been supported by Ministerio de Economía y Competitividad (SAF 14/57708-R) and co-funded by Fondo Europeo de Desarrollo Regional (FEDER), Unión Europea, and Una manera de hacer Europa (JH-R)