497 research outputs found

    Historia del Tiempo Presente y demanda social.

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    L’Europe médiane entre mémoire et histoire

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    Un regard français sur l’enseignement de l’histoire, dans différents pays de l’Europe médiane, permet d’appréhender l’évolution positive de cet enseignement, du primaire à l’université, malgré les innombrables difficultés matérielles et intellectuelles rencontrées

    Avian mortalities due to transmission line collisions: a review of current estimates and field methods with an emphasis on applications to the Canadian electric network

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    Birds are vulnerable to collisions with human-made fixed structures. Despite ongoing development and increases in infrastructure, we have few estimates of the magnitude of collision mortality. We reviewed the existing literature on avian mortality associated with transmission lines and derived an initial estimate for Canada. Estimating mortality from collisions with power lines is challenging due to the lack of studies, especially from sites within Canada, and due to uncertainty about the magnitude of detection biases. Detection of bird collisions with transmission lines varies due to habitat type, species size, and scavenging rates. In addition, birds can be crippled by the impact and subsequently die, although crippling rates are poorly known and rarely incorporated into estimates. We used existing data to derive a range of estimates of avian mortality associated with collisions with transmission lines in Canada by incorporating detection, scavenging, and crippling biases. There are 231,966 km of transmission lines across Canada, mostly in the boreal forest. Mortality estimates ranged from 1 million to 229.5 million birds per year, depending on the bias corrections applied. We consider our most realistic estimate, taking into account variation in risk across Canada, to range from 2.5 million to 25.6 million birds killed per year. Data from multiple studies across Canada and the northern U.S. indicate that the most vulnerable bird groups are (1) waterfowl, (2) grebes, (3) shorebirds, and (4) cranes, which is consistent with other studies. Populations of several groups that are vulnerable to collisions are increasing across Canada (e.g., waterfowl, raptors), which suggests that collision mortality, at current levels, is not limiting population growth. However, there may be impacts on other declining species, such as shorebirds and some species at risk, including Alberta's Trumpeter Swans (Cygnus buccinator) and western Canada's endangered Whooping Cranes (Grus americana). Collisions may be more common during migration, which underscores the need to understand impacts across the annual cycle. We emphasize that these estimates are preliminary, especially considering the absence of Canadian studies

    L'Estuaire (65)

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    Éditorial: La relance de la revue de l'Estuaire: 15 ans déjà! -- Le chemin de fer et le tourisme au Bas-Saint-Laurent -- Les dames Drapeau -- Histoire oubliée: Une étrange odyssée...des Madelinots s'établissent sur l'Île Nepawa (Abitibi) en 1941 -- Étude démographique de la population de Rimouski 1701-1750 -- Sur la piste des forêts du passé -- Mgr Courchesne: la récupération des forêts pour la colonisation -- Joseph-Pierre Ouellet, 2e architecte de l'église de Trois-Pistoles -- La seigneurie de l'Anse-aux-Coques ou de Lepage-Thivierge -- Nouvelles brèves -- Livres à lir

    L'Estuaire (73)

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    Éditorial -- Présence autochtone à la Maison Louis-Bertrand -- Le métissage au Bas-Saint-Laurent (1685-1849) -- Transformation du tissu urbain de la ville de Rimouski entre 1948 et 2004 -- La Buick Jouvin-Desrosiers -- SECTION SPÉCIALISÉE: Denis Riverin et la Compagnie des pêches sédentaires au Canada : les difficultés d'implantation d'une industrie de la pêche en Nouvelle-France (suite et fin) -- CHRONIQUES: Vieux écrits : La grande « détresse » de 1816 -- Des livres à lire

    L'Estuaire, vol. 24 (1)

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    Éditorial -- Mémoires de guerre d'un Gaspésien -- Emmanuel Coulombe : sur la route d'un menuisier -- Rimouski au temps d'Adèle Lamontagne 1858-1875. Partie 3: Commerce et société -- La pêche au saumon dans l'anse aux Coques -- Le Bas-Saint-Laurent et le fleuve: des relations disparues -- L'aéroport de Rimouski: quelques notes historiques -- Chroniques rimouskoises: Le Séminaire de Rimouski (1863-1967): repères chronologiques -- Vieux écrits: Marius Barbeau et le folklore de la côte nord gaspésienne -- Nouvelles brèves -- Des livres à lire

    Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma.

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    International audienceWe attempted to describe, in a series of clear cell renal cell carcinoma (RCC), the relationship between CAIX expression, VHL gene mutations, tumor characteristics and outcome. Radical nephrectomy was performed in 100 patients. Genomic DNA was extracted from frozen tumor samples. Four amplimers covering the whole coding sequence of the VHL gene were synthesized by PCR and sequenced. The monoclonal antibody M75 was used to evaluate CAIX protein expression immunohistochemically. VHL mutations were identified in 58 patients (58%) and high CAIX expression (>85%) was observed in 78 (78%). Tumors with VHL mutation showed higher CAIX expression than those without (p = 0.02). Low CAIX expression and absence of VHL mutation were associated with a more advanced tumors e.g., higher T stages and presence of metastases. VHL mutation and high CAIX expression predicted longer progression-free survival (p = 0.037) and disease-specific survival (p = 0.001), respectively. In combination, they defined three prognostic groups (p = 0.002): (i) good prognosis, defined as VHL mutation and high CAIX (2-year survival: 86%), (ii) intermediate prognosis with either VHL mutation or high CAIX (69%), and (iii) poor prognosis with no VHL mutation and low CAIX (45%, median survival 18 months). CAIX expression, but not VHL mutational status, was an independent prognostic factor in multivariate analysis. Taken together, CAIX expression and VHL mutational status are able to stratify patients with clear cell RCC into distinct groups with regards to clinicopathological variables and prognosis, with low CAIX expression and absence of VHL mutation being associated with a poor clinicopathological phenotype and diminished survival

    Predicting the distribution of canine leishmaniasis in western Europe based on environmental variables.

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    The domestic dog is the reservoir host of Leishmania infantum, the causative agent of zoonotic visceral leishmaniasis endemic in Mediterranean Europe. Targeted control requires predictive risk maps of canine leishmaniasis (CanL), which are now explored. We databased 2187 published and unpublished surveys of CanL in southern Europe. A total of 947 western surveys met inclusion criteria for analysis, including serological identification of infection (504, 369 dogs tested 1971-2006). Seroprevalence was 23 2% overall (median 10%). Logistic regression models within a GIS framework identified the main environmental predictors of CanL seroprevalence in Portugal, Spain, France and Italy, or in France alone. A 10-fold cross-validation approach determined model capacity to predict point-values of seroprevalence and the correct seroprevalence class (20%). Both the four-country and France-only models performed reasonably well for predicting correctly the 20% seroprevalence classes (AUC >0 70). However, the France-only model performed much better for France than the four-country model. The four-country model adequately predicted regions of CanL emergence in northern Italy (<5% seroprevalence). Both models poorly predicted intermediate point seroprevalences (5-20%) within regional foci, because surveys were biased towards known rural foci and Mediterranean bioclimates. Our recommendations for standardizing surveys would permit higher-resolution risk mapping
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