24 research outputs found
Food habits of Steller sea lions (Eumetopias jubatus) off Oregon and northern California, 1986–2007
We described the diet of the eastern stock of Steller sea lions (Eumetopias jubatus) from 1416 scat samples collected from five sites in Oregon and northern California from 1986 through 2007. A total of 47 prey types from 30 families were
identified. The most common prey was Pacific hake (Merluccius productus), followed by salmonids (Oncorhynchus
spp.), skates (Rajidae), Pacific lamprey (Lampetra tridentata), herrings (Clupeidae), rockfish (Sebastes spp.),
and northern anchovy (Engraulis mordax). Steller sea lion diet composition varied seasonally, annually, and spatially. Hake and salmonids were the most commonly identified prey in scats collected during the summer
(breeding season), whereas hake and skate were most common in the nonbreeding season. Continued research on Steller sea lion diet and foraging behavior in the southern extent of their range is necessary to address issues such as climate change, interaction with competing California sea
lions, and predation impacts on valuable or sensitive fish stocks
The Walk-in Counselling Model of Service Delivery: Who Benefits Most?
The walk-in counselling (WIC) model of service delivery has been found to reduce psychological distress more quickly than a traditional model of service delivery involving a wait list. A question remains, however, as to the relative benefit of the WIC model for different client groups. The present study uses graphical inspection and multilevel modeling to conduct moderator analyses comparing two agencies, one with a WIC clinic and the other with a traditional wait list approach, and their relative impact on psychological distress. Key findings regarding the differential benefits for different types of presenting problems as well as clients at different stages of change are discussed.
La recherche montre qu\u27un service de consultation sans rendez-vous réduit la détresse psychologique plus rapidement qu\u27un modèle traditionnel fonctionnant avec liste d\u27attente. Les bénéfices relatifs du modèle de consultation sans rendez-vous pour différentes clientèles demeurent cependant méconnus. Cette étude utilise l\u27inspection de graphiques et la modélisation multiniveau afin de mener une analyse de modération qui compare deux cliniques: sans rendez-vous ou suivant le modèle traditionnel avec liste d\u27attente. L\u27étude examine les impacts relatifs de ces modèles sur la détresse psychologique. Les principaux résultats portent sur les bénéfices différentiels selon les problématiques de santé mentale présentées et selon les stades de changement des usagers
Verbal instructions override the meaning of facial expressions
Psychological research has long acknowledged that facial expressions can implicitly trigger affective
psychophysiological responses. However, whether verbal information can alter the meaning of facial
emotions and corresponding response patterns has not been tested. This study examined emotional
facial expressions as cues for instructed threat-of-shock or safety, with a focus on defensive responding.
In addition, reversal instructions were introduced to test the impact of explicit safety instructions on
fear extinction. Forty participants were instructed that they would receive unpleasant electric shocks,
for instance, when viewing happy but not angry faces. In a second block, instructions were reversed
(e.g., now angry faces cued shock). Happy, neutral, and angry faces were repeatedly presented, and
auditory startle probes were delivered in half of the trials. The defensive startle reflex was potentiated
for threat compared to safety cues. Importantly, this effect occurred regardless of whether threat
was cued by happy or angry expressions. Although the typical pattern of response habituation was
observed, defense activation to newly instructed threat cues remained significantly enhanced in the
second part of the experiment, and it was more pronounced in more socially anxious participants.
Thus, anxious individuals did not exhibit more pronounced defense activation compared to less anxious
participants, but their defense activation was more persistent
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Sodium MRI with 3D-cones as a measure of tumour cellularity in high grade serous ovarian cancer.
The aim of this study was to assess the feasibility of rapid sodium MRI (23Na-MRI) for the imaging of peritoneal cancer deposits in high grade serous ovarian cancer (HGSOC) and to evaluate the relationship of 23Na-MRI with tumour cellularity. 23Na-MRI was performed at 3 T on twelve HGSOC patients using a 3D-cones acquisition technique. Tumour biopsies specimens were collected after imaging and cellularity was measured from histology. Total 23Na-MRI scan time for each patient was approximately 11 min. At an isotropic resolution of 5.6 mm, signal-to-noise ratios (SNRs) of 82.2 ± 15.3 and 15.1 ± 7.1 (mean ± standard deviation) were achieved for imaging of tumour tissue sodium concentration (TSC) and intracellular weighted sodium concentration (IWS) respectively. Tumour TSC and IWS concentrations were: 56.8 ± 19.1 mM and 30.8 ± 9.2 mM respectively and skeletal muscle TSC and IWS concentrations were 33.2 ± 16.3 mM and 20.5 ± 9.9 mM respectively. There were significant sodium concentration differences between cancer and skeletal muscle, Wilcoxon signed-rank test, P <  0.001 for TSC and P =  0.01 for IWS imaging. Tumour cellularity displayed a strong negative correlation with TSC, Spearman's rho = -0.92, P <  0.001, but did not correlate with IWS. This study demonstrates that 23Na-MRI using 3D-cones can rapidly assess sodium concentration in peritoneal deposits of HGSOC and that TSC may serve as a biomarker of tumour cellularity.CRU
Dynamic Chromatin Organization during Foregut Development Mediated by the Organ Selector Gene PHA-4/FoxA
Central regulators of cell fate, or selector genes, establish the identity of cells by direct regulation of large cohorts of genes. In Caenorhabditis elegans, foregut (or pharynx) identity relies on the FoxA transcription factor PHA-4, which activates different sets of target genes at various times and in diverse cellular environments. An outstanding question is how PHA-4 distinguishes between target genes for appropriate transcriptional control. We have used the Nuclear Spot Assay and GFP reporters to examine PHA-4 interactions with target promoters in living embryos and with single cell resolution. While PHA-4 was found throughout the digestive tract, binding and activation of pharyngeally expressed promoters was restricted to a subset of pharyngeal cells and excluded from the intestine. An RNAi screen of candidate nuclear factors identified emerin (emr-1) as a negative regulator of PHA-4 binding within the pharynx, but emr-1 did not modulate PHA-4 binding in the intestine. Upon promoter association, PHA-4 induced large-scale chromatin de-compaction, which, we hypothesize, may facilitate promoter access and productive transcription. Our results reveal two tiers of PHA-4 regulation. PHA-4 binding is prohibited in intestinal cells, preventing target gene expression in that organ. PHA-4 binding within the pharynx is limited by the nuclear lamina component EMR-1/emerin. The data suggest that association of PHA-4 with its targets is a regulated step that contributes to promoter selectivity during organ formation. We speculate that global re-organization of chromatin architecture upon PHA-4 binding promotes competence of pharyngeal gene transcription and, by extension, foregut development
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Pinniped food habits in Oregon
The purpose of this investigation was to determine if pinniped feeding patterns have significant negative impacts on depressed salmonid stocks. Knowledge about prey selection by pinnipeds is key to assessing their potential impact on salmonid stocks. The four major work elements reported are: 1) the reanalysis of Columbia River area scat samples collected in the early 1980's; 2) examination of California sea lion (Zalophus calironianus), Pacific harbor seal (Phoca vitulina), and Steller sea lion (Eumetopias jubatus) scat; 3) determination of salmonid size from recently collected gastrointestinal tract samples from the Columbia River; and 4) examination of previously collected pinniped scat samples from the southern Oregon coast. In addition pinniped prey items were identified from previous scat collections made in Siletz Bay, Alsea Bay, and the Umpqua River, along with a comparison of lavage, enema and scat samples collected in the Columbia River
Appendix A. Aerial photographs of the Alsea River estuary, Oregon, USA.
Aerial photographs of the Alsea River estuary, Oregon, USA
Appendix C. A table showing reaction conditions and concentrations for microsatellite loci used to genotype salmonid bones recovered from harbor seal scat from Alsea River estuary, Orgeon, USA.
A table showing reaction conditions and concentrations for microsatellite loci used to genotype salmonid bones recovered from harbor seal scat from Alsea River estuary, Orgeon, USA