6 research outputs found
The expression of IGF-1R in <i>Helicobacter pylori</i>-infected intestinal metaplasia and gastric cancer
Anomalous Dependence of Translational Diffusion on the Water Mole Fraction for Solute Molecules Dissolved in a 1‑Butyl-3-methylimidazolium Tetrafluoroborate/Water Mixture
Translational diffusion coefficients of carbon monoxide
(CO), diphenylacetylene
(DPA), and diphenylcyclopropenone (DPCP) were determined in mixtures
of 1-butyl-3-methylimidazolium tetrafluoroborate ([C4mim]BF4) and water using transient grating spectroscopy at different
mole fractions of water (xw). While DPA
exhibited a larger diffusion coefficient than DPCP at low water mole
fractions (xw < 0.7), as observed for
conventional liquids and ionic liquids (ILs), it was smaller at high
mole fractions (xw > 0.9). The apparent
molecular radius of DPA determined using the Stokes–Einstein
equation at xw > 0.9 is close to the
radius
of an IL cluster in a water pool as determined from small-angle neutron
scattering experiments (J. Bowers et al., Langmuir, 2004, 20, 2192–2198), suggesting that the DPA
molecules are trapped in IL clusters in the water pool and move together.
The solvation state of DPCP in the mixture was studied using Raman
spectroscopy. Dramatically strong water/DPCP hydrogen bonding was
observed at higher water mole fractions, suggesting that DPCP is located
near the cluster interfaces. The large diffusion coefficient of DPCP
suggests that hopping of DPCP between IL clusters occurs through hydrogen
bonding with water
ASSESSMENT OF BASILAR ARTERY HEMODYNAMICS IN TYPE 2 DIABETIC PATIENTS WITH NO HISTORY OF CEREBROVASCULAR DISEASE BY USING TRANSCRANIAL DOPPLER ULTRASOUND
We compared intracranial hemodynamics in 121 type 2 diabetic patients
who had no history of cerebrovascular disease with findings in 123 matched control
subjects. Mean blood flow velocity (MFV) and Fourier pulsatility index were determined
by using transcranial Doppler ultrasonography (TCD). MFV in the basilar artery was
significantly lower in diabetic than in nondiabetic subjects (p<0.01), while Fourier PI of
the basilar artery was significantly higher in diabetic than in nondiabetic subjects
(p<0.01). In multivariate regression analysis, increased Fourier PI and decreased MFV
were associated with higher age, female gender, and longer duration of diabetes.
Decreased MFV was also associated with microalbuminuria. These findings
demonstrated deterioration of basilar artery hemodynamics in patients with type 2
diabetes who have no stroke history. Additionally, repeated TCD may prove to be useful
for monitoring cerebrovascular impairments in these patients