Changes induced by the containment measures of the first COVID-19 wave: a scoping review on work-family balance regarding working parents

In March 2020, COVID-19 was declared a worldwide pandemic. To limit its spread, governments and institutions have implemented drastic measures with major repercussions on the labor market, workers, and their families. Business, school, and daycare closures, as well as telework and home-schooling, have challenged working parents. In this unique context, researchers have examined COVID-19’s effects on work and family. Using the PRISMA-ScR guidelines, this scoping review explores, classifies, synthesizes, and analyzes the research findings from the first wave of the COVID-19 pandemic on work-family balance issues. More specifically, it examines how contextual forces hindered or facilitated working parents’ time management and work-family balance, along with coping strategies they implemented. Searches were conducted in 18 databases to identify relevant French or English peer-reviewed empirical articles published before April 2021. Articles should include information on parent workers at the first wave of the pandemic. Of the 570 papers identified, 56 were retained and synthesized. The articles cover worldwide populations, with one-quarter from the USA. Based on the Decision-action model, a thematic analysis allows identifying how the experience of the early months of the pandemic affects the life course of working parents and the work-family balance project considering the contextual forces to which they were exposed, and the strategies deployed to meet their needs. Findings reveal the fragility of the work-family balance among working parents and the disorganization caused by a major social crisis. They also highlight the importance of individual, organizational and governmental strategies to better support workers, families, businesses and communities

Jakuta Alikavazovic, La blonde et le bunker derrière le miroir…

Le roman que nous propose la romancière française, née en 1979, après le prix Goncourt du premier roman avec Les corps Volatils, a remporté la mention spéciale du jury Wepler. Et l’œuvre perturbe en effet tous nos repères, réalisant les aspirations de son auteure : « L’originalité dans la répétition. Le déjà-vu comme condition du sens, et paradoxalement comme irruption de la nouveauté. » Impossible de se raccrocher longtemps au désir d’élucidation, moteur du roman noir, tant la narration joue du speculum, à la fois jeux de regards et de miroirs, et spéculations de toutes sortes. Et pourtant, Jakuta Alikavazovic a éveillé notre curiosité et notre instinct de détective. C’est pourquoi nous vous proposons de nous suivre dans cette enquête, sur les traces du récit, avec pour seul indice celui qu’a laissé l’auteure derrière elle : « L’un des thèmes de La blonde et le bunker (comme de tous mes livres) est la disparition

Jakuta Alikavazovic, La blonde et le bunker derrière le miroir…

Le roman que nous propose la romancière française, née en 1979, après le prix Goncourt du premier roman avec Les corps Volatils, a remporté la mention spéciale du jury Wepler. Et l’œuvre perturbe en effet tous nos repères, réalisant les aspirations de son auteure : « L’originalité dans la répétition. Le déjà-vu comme condition du sens, et paradoxalement comme irruption de la nouveauté. » Impossible de se raccrocher longtemps au désir d’élucidation, moteur du roman noir, tant la narration joue du speculum, à la fois jeux de regards et de miroirs, et spéculations de toutes sortes. Et pourtant, Jakuta Alikavazovic a éveillé notre curiosité et notre instinct de détective. C’est pourquoi nous vous proposons de nous suivre dans cette enquête, sur les traces du récit, avec pour seul indice celui qu’a laissé l’auteure derrière elle : « L’un des thèmes de La blonde et le bunker (comme de tous mes livres) est la disparition

Type 1 Diabetes in People Hospitalized for COVID-19: New Insights From the CORONADO Study

International audienc

The association between macrovascular complications and intensive care admission, invasive mechanical ventilation, and mortality in people with diabetes hospitalized for coronavirus disease-2019 (COVID-19)

International audienceAbstract Background It is not clear whether pre-existing macrovascular complications (ischemic heart disease, stroke or peripheral artery disease) are associated with health outcomes in people with diabetes mellitus hospitalized for COVID-19. Methods We conducted cohort studies of adults with pre-existing diabetes hospitalized for COVID-19 infection in the UK, France, and Spain during the early phase of the pandemic (between March 2020—October 2020). Logistic regression models adjusted for demographic factors and other comorbidities were used to determine associations between previous macrovascular disease and relevant clinical outcomes: mortality, intensive care unit (ICU) admission and use of invasive mechanical ventilation (IMV) during the hospitalization. Output from individual logistic regression models for each cohort was combined in a meta-analysis. Results Complete data were available for 4,106 (60.4%) individuals. Of these, 1,652 (40.2%) had any prior macrovascular disease of whom 28.5% of patients died. Mortality was higher for people with compared to those without previous macrovascular disease (37.7% vs 22.4%). The combined crude odds ratio (OR) for previous macrovascular disease and mortality for all four cohorts was 2.12 (95% CI 1.83–2.45 with an I 2 of 60%, reduced after adjustments for age, sex, type of diabetes, hypertension, microvascular disease, ethnicity, and BMI to adjusted OR 1.53 [95% CI 1.29–1.81]) for the three cohorts. Further analysis revealed that ischemic heart disease and cerebrovascular disease were the main contributors of adverse outcomes. However, proportions of people admitted to ICU (adjOR 0.48 [95% CI 0.31–0.75], I 2 60%) and the use of IMV during hospitalization (adjOR 0.52 [95% CI 0.40–0.68], I 2 37%) were significantly lower for people with previous macrovascular disease. Conclusions This large multinational study of people with diabetes mellitus hospitalized for COVID-19 demonstrates that previous macrovascular disease is associated with higher mortality and lower proportions admitted to ICU and treated with IMV during hospitalization suggesting selective admission criteria. Our findings highlight the importance correctly assess the prognosis and intensive monitoring in this high-risk group of patients and emphasize the need to design specific public health programs aimed to prevent SARS-CoV-2 infection in this subgroup

A global metagenomic map of urban microbiomes and antimicrobial resistance

We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species of urban microorganisms and a consistent set of 31 species found in 97% of samples that were distinct from human commensal organisms. Profiles of AMR genes varied widely in type and density across cities. Cities showed distinct microbial taxonomic signatures that were driven by climate and geographic differences. These results constitute a high-resolution global metagenomic atlas that enables discovery of organisms and genes, highlights potential public health and forensic applications, and provides a culture-independent view of AMR burden in cities.Funding: the Tri-I Program in Computational Biology and Medicine (CBM) funded by NIH grant 1T32GM083937; GitHub; Philip Blood and the Extreme Science and Engineering Discovery Environment (XSEDE), supported by NSF grant number ACI-1548562 and NSF award number ACI-1445606; NASA (NNX14AH50G, NNX17AB26G), the NIH (R01AI151059, R25EB020393, R21AI129851, R35GM138152, U01DA053941); STARR Foundation (I13- 0052); LLS (MCL7001-18, LLS 9238-16, LLS-MCL7001-18); the NSF (1840275); the Bill and Melinda Gates Foundation (OPP1151054); the Alfred P. Sloan Foundation (G-2015-13964); Swiss National Science Foundation grant number 407540_167331; NIH award number UL1TR000457; the US Department of Energy Joint Genome Institute under contract number DE-AC02-05CH11231; the National Energy Research Scientific Computing Center, supported by the Office of Science of the US Department of Energy; Stockholm Health Authority grant SLL 20160933; the Institut Pasteur Korea; an NRF Korea grant (NRF-2014K1A4A7A01074645, 2017M3A9G6068246); the CONICYT Fondecyt Iniciación grants 11140666 and 11160905; Keio University Funds for Individual Research; funds from the Yamagata prefectural government and the city of Tsuruoka; JSPS KAKENHI grant number 20K10436; the bilateral AT-UA collaboration fund (WTZ:UA 02/2019; Ministry of Education and Science of Ukraine, UA:M/84-2019, M/126-2020); Kyiv Academic Univeristy; Ministry of Education and Science of Ukraine project numbers 0118U100290 and 0120U101734; Centro de Excelencia Severo Ochoa 2013–2017; the CERCA Programme / Generalitat de Catalunya; the CRG-Novartis-Africa mobility program 2016; research funds from National Cheng Kung University and the Ministry of Science and Technology; Taiwan (MOST grant number 106-2321-B-006-016); we thank all the volunteers who made sampling NYC possible, Minciencias (project no. 639677758300), CNPq (EDN - 309973/2015-5), the Open Research Fund of Key Laboratory of Advanced Theory and Application in Statistics and Data Science – MOE, ECNU, the Research Grants Council of Hong Kong through project 11215017, National Key RD Project of China (2018YFE0201603), and Shanghai Municipal Science and Technology Major Project (2017SHZDZX01) (L.S.