615 research outputs found

    Discover your Wesleyan DNA : a curriculum for the Wesleyan Methodist Church of New Zealand

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    https://place.asburyseminary.edu/ecommonsatsdissertations/1384/thumbnail.jp

    A History of the Board of Engineers for Rivers and Harbors

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    CHAPTER I: THE BOARD IS ESTABLISHEDTheodore F. Burton • Constituting the Board CHAPTER II: STARTING BUSINESSFirst Board Members • Location • The First Reviews • Early Board Reviews • Public Hearings • Board Meetings • Expenses • Staff CHAPTER III: THE MISSIONS OF THE BOARDThe Primary Mission • The Review Process • Assigned Missions • Planning Associates Program • Waterborne Commerce Statistics • Permanent International Association of • Navigation Congresses (PIANC) • Foreign Trade Zones • Processing Reports for State and • Washington-Level Agency Review • Former Missions • Marine Design • Transportation Economics • National Capital Planning Commission • Port Series Reports CHAPTER IV: THE EARLY MOLDING OF THE BOARD\u27S ROLEIndependent Review • Shaping Corps Policy • Maintenance of single-user channel • Specific Federal cost limitation • Lands and allocations • Reasonable cost • Considering alternatives • Separation of military needs • Analysis of navigation systems • Limited Federal interest • Moving Projects Forward • Early Congressional Pressure • Processing Reports • Board-Chief of Engineers Conflict CHAPTER V: THE ORGANIZATIONIntroduction 68 • The Senior Members and Chairmen 69 • The Resident Member 82 • The Board Members 91 • The Technical Director 99 • The Special Assistant 102 • The Military Assistant 105 • Present 106 • The Planning Division 106 • The Evaluation Division 108 • The Environmental Division 114 • The Professional Development Division 115 • Past 115 • The Port Facilities Division 115 • The Transportation Economics Division 121 • The Marine Design Division 122 • The Statistical Division 126 • The Resident Scholars 128 • Office, Chief of Engineers (OCE) Details 131 CHAPTER VI: MAJOR BOARD IMPACTS1906 - Cumberland River • 1907 - Ohio River • 1908 - Missouri River • 1911 - Intracoastal Waterway • 1924 - Gulf Intracoastal Waterway (GIWW) • 1925 - St. Lawrence River Project • 1925 - The Flood Control Mis sion • 1930 - Tennessee River and Tributaries • 1942 - The New Jersey Ship Canal • 1942 - Cross -Florida Barge Canal • 1943 - Missouri River (Pick-Sloan Plan) • 1945 - Tennessee-Tombigbee Waterway • 1945 - Arkansas River Navigation • 1946 - Red River, Louisiana, Arkansas, Oklahoma, and Texas ( Overton-Red River Waterway) • 1952 - Inland Waterway from Delaware River to Chesapeake Bay, Delaware and Maryland ( The Chesapeake and Delaware Canal) • 1972 - • 1973 Passaic River, New Jersey • 1976 - Locks and Dam No. 26, Mississippi • River, Alton, Illinois - Replacement • SUMMARY CHAPTER VII: THE PRESENT AND THE FUTUREThe Board\u27s Permanent Home • The Staff • The Futur

    The stability of Mars' annular polar vortex

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    This research was partially supported by a NASA grant from the Mars Fundamental Research Program (NNX14AG53G).The Martian polar atmosphere is known to have a persistent local minimum in potential vorticity (PV) near the winter pole, with a region of high PV encircling it. This finding is surprising since an isolated band of PV is barotropically unstable, a result going back to Rayleigh. Here we investigate the stability of a Mars-like annular vortex using numerical integrations of the rotating shallow water equations. We show how the mode of instability and its growth rate depends upon the latitude and width of the annulus. By introducing thermal relaxation towards an annular equilibrium profile with a time scale similar to that of the instability, we are able to simulate a persistent annular vortex with similar characteristics as that observed in the Martian atmosphere. This time scale, typically 0.5-2 sols, is similar to radiative relaxation time scales for Mars’ polar atmosphere. We also demonstrate that the persistence of an annular vortex is robust to topographic forcing, as long as it is below a certain amplitude. We hence propose that the persistence of this barotropically unstable annular vortex is permitted due to the combination of short radiative relaxation time scales and relatively weak topographic forcing in the Martian polar atmosphere.Publisher PDFPeer reviewe

    A Microcantilever Device to Assess the Effect of Force on the Lifetime of Selectin-Carbohydrate Bonds

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    A microcantilever technique was used to apply force to receptor-ligand molecules involved in leukocyte rolling on blood vessel walls. E-selectin was adsorbed onto 3-μm-diameter, 4-mm-long glass fibers, and the selectin ligand, sialyl Lewisx, was coupled to latex microspheres. After binding, the microsphere and bound fiber were retracted using a computerized loading protocol that combines hydrodynamic and Hookean forces on the fiber to produce a range of force loading rates (force/time), rf. From the distribution of forces at failure, the average force was determined and plotted as a function of ln rf. The slope and intercept of the plot yield the unstressed reverse reaction rate, kro , and a parameter that describes the force dependence of reverse reaction rates, ro. The ligand was titrated so adhesion occurred in ~30% of tests, implying that \u3e80% of adhesive events involve single bonds. Monte Carlo simulations show that this level of multiple bonding has little effect on parameter estimation. The estimates are ro = 0.048 and 0.016 nm and kro = 0.72 and 2.2 s-1 for loading rates in the ranges 200–1000 and 1000–5000 pN s-1, respectively. Levenberg-Marquardt fitting across all values of rf gives ro = 0.034 nm and kro = 0.82 s-1. The values of these parameters are in the range required for rolling, as suggested by adhesive dynamics simulations

    Narrowing of the Upwelling Branch of the Brewer-Dobson Circulation and Hadley Cell in Chemistry-Climate Model Simulations of the 21st Century

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    Changes in the width of the upwelling branch of the Brewer-Dobson circulation and Hadley cell in the 21st Century are investigated using simulations from a coupled chemistry-climate model. In these model simulations the tropical upwelling region narrows in the troposphere and lower stratosphere. The narrowing of the Brewer-Dobson circulation is caused by an equatorward shift of Rossby wave critical latitudes and Eliassen-Palm flux convergence in the subtropical lower stratosphere. In the troposphere, the model projects an expansion of the Hadley cell's poleward boundary, but a narrowing of the Hadley rising branch. Model results suggest that the narrowing of the Hadley cell ascent is also eddy-driven

    Ergo Hackathon: Crowdfunded Smart Contract Pools Research and Conceptualization

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    This is team SmartPools’ submission for the first Ergo Hackathon. It suggests that Ergo lacks the decentralization, and focus on regular people that it was designed for, and presents a potential solution for these problems in laying the framework for crowdfunded smart contract pools compatible with non-outsourceabilty. It should allow for pool formation with a greater level of decentralization than previously possible by including metrics for diminishing returns on over-contributing hash power to pools with data gathered from Ergo Oracles. This work is informal and preliminary. Further research is required to formalize this work and attempt to provide functional proof for its arguments; readers are highly encouraged to read the included references, and their references, for greater clarity

    Reductions of erythrocyte membrane viscoelastic coefficients reflect spectrin deficiencies in hereditary spherocytosis

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    Hereditary spherocytosis is a common hemolytic anemia associated with deficiencies in spectrin, the principal structural protein of the erythrocyte membrane-skeleton. We have examined 20 different individuals from 10 spherocytosis kindreds and 2 elliptocytosis kindreds to determine the effects of different levels of spectrin deficiency on the viscoelastic properties of the erythrocyte membrane. Micropipettes were used to perform single-cell micromechanical measurements of approximately 1,000 individual cells to determine the membrane elastic shear modulus, the apparent membrane bending stiffness, and whole cell recovery time constant for the different cell populations. The membrane viscosity was calculated by the product of the shear modulus and the recovery time constant. Results show correlation between the fractional reduction in shear modulus and the fractional reduction in spectrin content (determined by spectrin radioimmunoassay) and spectrin density (determined by the ratios of spectrin to band 3 on electrophoresis gels) suggesting that membrane shear elasticity is directly proportional to the surface density of spectrin on the membrane (P less than 0.001). The apparent membrane bending stiffness is also reduced in proportion to the density of spectrin (P less than 0.001). The membrane viscosity is reduced relative to control (P less than 0.001), but the nature of the relationship between spectrin density and membrane viscosity is less clearly defined. These studies document striking relationships between partial deficiencies of erythrocyte spectrin and specific viscoelastic properties of the mutant membranes

    Surgical management of complications following endoluminal grafting of abdominal aortic aneurysms

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    Objective:The aim of this study was to report the outcome of endoluminal grafting of abdominal aortic aneurysms (AAA) with special reference to complications.Methods:Between May 1992 and August 1994 endoluminal repair of aneurysms was undertaken in 61 patients. In 53 the aneurysm was aortic and these are the basis of this report. In patients with AAA all procedures were elective and were performed in the operating room with the patient draped for an open repair in the event of failed endoluminal repair. The configuration of the endografts was tubular 36, tapered aortoiliac/aortofemoral 12 and bifurcated 5. Radiographic guidance was used to pass the endografts into the aorta via a delivery sheath introduced through the femoral or iliac arteries.Results:Successful endoluminal repair of AAA was achieved in 43 of 53(81%) patients. In the remaining 10 patients, endoluminal repair was abandoned in favour of an open repair. There were 17(32%) local/vascular and 13(25%) systemic/remote complications. The sum of these complications occurring in successful endoluminal repairs and those complications leading to failure of endoluminal repair was 40(75%). There were two cardiac deaths within 30 days in patients undergoing endoluminal repair (both procedure related) and four late deaths (unrelated to aneurysm repair). Three of the late deaths were in patients undergoing endoluminal repair and one endoluminal converted to open repair.Conclusion:Endoluminal repair of AAA in our experience has a low perioperative (<30 days) mortality rate (3.7%) but a high morbidity rate (75%). It is recommended that complications be classified into three groups: systemic/remote and local/vascular (following successful endoluminal repair) plus those complications leading to failure of endoluminal repair. The first group is composed of medical complications while the latter two groups comprise those surgical complications directly related to the endoluminal technique

    Seasonal Variation of Ozone in the Tropical Lower Stratosphere: Southern Tropics are Different from Northern Tropics

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    We examine the seasonal behavior of ozone by using measurements from various instruments including ozonesondes, Aura Microwave Limb Sounder, and Stratospheric Aerosol and Gas Experiment II. We find that the magnitude of the annual variation in ozone, as a percentage of the mean ozone, exhibits a maximum at or slightly above the tropical tropopause. The maximum is larger in the northern tropics than in the southern tropics, and the annual maximum of ozone in the southern tropics occurs 2 months later than that in the northern tropics, in contrast to usual assumption that the tropics can be treated as a horizontally homogeneous region. The seasonal cycles of ozone and other species in this part of the lower stratosphere result from a combination of the seasonal variation of the Brewer-Dobson circulation and the seasonal variation of tropical and midlatitude mixing. In the Northern Hemisphere, the impacts of upwelling and mixing between the tropics and midlatitudes on ozone are in phase and additive. In the Southern Hemisphere, they are not in phase. We apply a tropical leaky pipe model independently to each hemisphere to examine the relative roles of upwelling and mixing in the northern and southern tropical regions. Reasonable assumptions of the seasonal variation of upwelling and mixing yield a good description of the seasonal magnitude and phase in both the southern and northern tropics. The differences in the tracers and transport between the northern and southern tropical stratospheres suggest that the paradigm of well-mixed tropics needs to be revised to consider latitudinal variations within the tropics

    Measurement of Pulmonary Flow Reserve and Pulmonary Index of Microcirculatory Resistance for Detection of Pulmonary Microvascular Obstruction

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    BACKGROUND: The pulmonary microcirculation is the chief regulatory site for resistance in the pulmonary circuit. Despite pulmonary microvascular dysfunction being implicated in the pathogenesis of several pulmonary vascular conditions, there are currently no techniques for the specific assessment of pulmonary microvascular integrity in humans. Peak hyperemic flow assessment using thermodilution-derived mean transit-time (T(mn)) facilitate accurate coronary microcirculatory evaluation, but remain unvalidated in the lung circulation. Using a high primate model, we aimed to explore the use of T(mn) as a surrogate of pulmonary blood flow for the purpose of measuring the novel indices Pulmonary Flow Reserve [PFR = (maximum hyperemic)/(basal flow)] and Pulmonary Index of Microcirculatory Resistance [PIMR = (maximum hyperemic distal pulmonary artery pressure)x(maximum hyperemic T(mn))]. Ultimately, we aimed to investigate the effect of progressive pulmonary microvascular obstruction on PFR and PIMR. METHODS AND RESULTS: Temperature- and pressure-sensor guidewires (TPSG) were placed in segmental pulmonary arteries (SPA) of 13 baboons and intravascular temperature measured. T(mn) and hemodynamics were recorded at rest and following intra-SPA administration of the vasodilator agents adenosine (10-400 microg/kg/min) and papaverine (3-24 mg). Temperature did not vary with intra-SPA sensor position (0.010+/-0.009 v 0.010+/-0.009 degrees C; distal v proximal; p = 0.1), supporting T(mn) use in lung for the purpose of hemodynamic indices derivation. Adenosine (to 200 microg/kg/min) & papaverine (to 24 mg) induced dose-dependent flow augmentations (40+/-7% & 35+/-13% T(mn) reductions v baseline, respectively; p<0.0001). PFR and PIMR were then calculated before and after progressive administration of ceramic microspheres into the SPA. Cumulative microsphere doses progressively reduced PFR (1.41+/-0.06, 1.26+/-0.19, 1.17+/-0.07 & 1.01+/-0.03; for 0, 10(4), 10(5) & 10(6) microspheres; p = 0.009) and increased PIMR (5.7+/-0.6, 6.3+/-1.0, 6.8+/-0.6 & 7.6+/-0.6 mmHg.sec; p = 0.0048). CONCLUSIONS: Thermodilution-derived mean transit time can be accurately and reproducibly measured in the pulmonary circulation using TPSG. Mean transit time-derived PFR and PIMR can be assessed using a TPSG and adenosine or papaverine as hyperemic agents. These novel indices detect progressive pulmonary microvascular obstruction and thus have with a potential role for pulmonary microcirculatory assessment in humans
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