1,566 research outputs found

    Orismological Sesquipedalianism in Advertising

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    Ecology and Management of Red-Winged Blackbirds

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    The red-winged blackbird (Agelaius phoeniceus) is one of the most abundant bird species in North America, with an estimated spring breeding population of 150 million individuals that nest in emergent wetland vegetation and upland habitats throughout the continent (Yasukawa and Searcy 1995; Forcey et al. 2015; Rosenberg et al. 2016). During the nonbreeding season, red-winged blackbirds are often found in flocks numbering from a few birds to many thousands, sometimes in association with other blackbird species and European starlings (Sturnus vulgaris). In winter, red-winged blackbirds and these associated species gather in roosts occasionally numbering over 10 million birds (Meanley and Royal 1976; White et al. 1985). Migratory male red-winged blackbirds typically arrive at their nesting grounds in early March, a month before the females arrive. At this time, casual bird watchers are apt to notice the robinsized, male red-winged blackbirds with black feathers and highly conspicuous red and yellow epaulets (definitive plumage), prominently displayed while aggressively confronting intruders approaching their nesting territories (Figure 2.1). Loud singing (o-ka-leeee, konk-a-ree) by these males from high perches in their chosen territories adds to their aesthetic value. Second-year males returning to their natal area following their hatching year do not have the definitive plumage of adults. Rather, they have a duller black body and light red or orange epaulets (Yasukawa and Searcy 1995). The female, at least 20% smaller and far less noticeable with brownish feathers, is often misidentified as a large streaked sparrow (Figure 2.2) (Yasukawa and Searcy 1995; Jaramillo and Burke 1999)

    Primary hemiarthroplasty for treatment of proximal humeral fractures

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    Background: Primary hemiarthroplasty of the shoulder is used to treat complex proximal humeral fractures, although the reported functional results following this method of treatment have varied widely. The aim of this study was to prospectively assess the prosthetic survival and functional outcomes in a large series of patients treated with shoulder hemiarthroplasty for a proximal humeral fracture. By determining the factors that affected the outcome, we also aimed to produce models that could be used clinically to estimate the functional outcome at one year following surgery.Methods: A thirteen-year observational cohort study of 163 consecutive patients treated with hemiarthroplasty for a proximal humeral fracture was performed. Twenty-five patients died or were lost to follow-up in the first year after treatment, leaving 138 patients who had assessment of shoulder function with use of the modified Constant score at one year postinjury.Results: The overall rate of prosthetic survival was 96.9% at one year, 95.3% at five years, and 93.9% at ten years. The overall median modified Constant score was 64 points at one year, with a typically good score for pain relief (median, 15 points) and poorer scores, with a greater scatter of values, for function (median, 12 points), range of motion (median, 24 points), and muscle power (median, 14 points). Of the factors that were assessed immediately after the injury, only patient age, the presence of a neurological deficit, tobacco usage, and alcohol consumption were significantly predictive of the one-year Constant score (p &lt; 0.05). Of the factors that were assessed at six weeks postinjury, those that predicted the one-year Constant score included the age of the patient, the presence of a persistent neurological deficit, the need for an early reoperation, the degree of displacement of the prosthetic head from the central axis of the glenoid seen radiographically, and the degree of displacement of the tuberosities seen radiographically.Conclusions: Primary shoulder hemiarthroplasty performed for the treatment of a proximal humeral fracture in medically fit and cooperative adults is associated with satisfactory prosthetic survival at an average of 6.3 years. Although the shoulder is usually free of pain following this procedure, the overall functional result, in terms of range of motion, function, and power, at one year varies. A good functional outcome can be anticipated for a younger individual who has no preoperative neurological deficit, no postoperative complications, and a satisfactory radiographic appearance of the shoulder at six weeks. The results are poorer in the larger group of elderly patients who undergo this procedure, especially if they have a neurological deficit, a postoperative complication requiring a reoperation, or an eccentrically located prosthesis with retracted tuberosities.<br /

    FY19 Final Report | Scholarship & Innovation: an Inquiry 2018-2019

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    The IMSA Scholarship and Innovation Committee was established in August, 2019 by Dr. José Torres based on report recommendations from Research Fellow, Dr. Page as a way to deepen a culture of scholarship, research and innovation across the IMSA community. The purpose of the committee is to create and communicate a shared vision, meaning and support for scholarship and innovation at IMSA, continuing its long tradition as a leading learning laboratory.https://digitalcommons.imsa.edu/si/1000/thumbnail.jp

    FY20 Community Day Presentation | Scholarship & Innovation: An Inquiry 2018-2019

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    Presentation at Community Day | 8.14.2019https://digitalcommons.imsa.edu/si/1001/thumbnail.jp

    An examination of in-season external training load in semi-professional soccer players: considerations of one and two match weekly microcycles

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    The aim of the present study was to firstly, quantify the external training load (TL) of semi-professional soccer players during an annual season and secondly, to examine the influence of one (1MW) and two (2MW) match weekly microcycles. Data were collected from 24 semi-professional outfield soccer players during the 2018-2019 annual season using micro-electromechanical system (MEMS) devices for the following variables: Training duration (min), total distance (TD), Player Load (PL), high speed running (HSR) distance (5.5-7.0 m/s), and acceleration (ACC) efforts (>2 m/s2). Training sessions were defined as days before match day (i.e. MD minus), with match weeks broken down as either 1MW or 2MW. Data revealed higher TD, PL, and HSR distance on MD and MD-5 when compared to all other MD codes. MD-4 displayed significantly higher values compared to MD-1 (mean differences (Mdiff): TD: 785 ± 158 m; PL: 29 ± 9 au; HSR: 192 ± 63 m; ACC: 15 ± 3 #) and MD-2 (Mdiff: TD: 279 ± 137 m; HSR: 127 ± 54 m). During 2MW scenarios, both TD (Mdiff: 685 ± 328 m) and PL (Mdiff: 33 ± 14 au) were higher on MD-1 when compared to 1MW. However, lower values were observed for duration and HSR on MD-2 and MD-4 during 2MW compared to 1MW scenarios. These data suggest that there appears to be a progressive reduction in TD, PL, HSR and ACC leading into competitive matches based on MD- analysis. However, some variability exists in TL prescription as a result of different MW scenarios (i.e. 1MW vs. 2MW)

    Association of a genetic polymorphism (-44 C/G SNP) in the human DEFB1 gene with expression and inducibility of multiple β-defensins in gingival keratinocytes

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    BACKGROUND: Human β-defensins (hBDs) are antimicrobial peptides with a role in innate immune defense. Our laboratory previously showed that a single nucleotide polymorphism (SNP) in the 5' untranslated region of the hBD1 gene (DEFB1), denoted -44 (rs1800972), is correlated with protection from oral Candida. Because this SNP alters the putative mRNA structure, we hypothesized that it alters hBD1 expression. METHODS: Transfection of reporter constructs and evaluation of antimicrobial activity and mRNA expression levels in keratinocytes from multiple donors were used to evaluate the effect of this SNP on constitutive and induced levels of expression. RESULTS: Transfection of CAT reporter constructs containing the 5' untranslated region showed that the -44 G allele yielded a 2-fold increase in CAT protein compared to other common haplotypes suggesting a cis effect on transcription or translation. The constitutive hBD1 mRNA level in human oral keratinocytes was significantly greater in cells from donors with the -44 GG genotype compared to those with the common CC genotype. Surprisingly, the hBD3 mRNA level as well as antimicrobial activity of keratinocyte extracts also correlated with the -44 G allele. Induced levels of hBD1, hBD2, and hBD3 mRNA were evaluated in keratinocytes challenged with Toll-like receptor 2 and 4 ligands, interleukin-1β, TNFα, and interferon-γ (IFNγ). In contrast to constitutive expression levels, IFNγ-induced keratinocyte hBD1 and hBD3 mRNA expression was significantly greater in cells with the common CC genotype, but there was no clear correlation of genotype with hBD2 expression. CONCLUSION: The DEFB1 -44 G allele is associated with an increase in overall constitutive antimicrobial activity and expression of hBD1 and hBD3 in a manner that is consistent with protection from candidiasis, while the more common C allele is associated with IFNγ inducibility of these β-defensins and is likely to be more protective in conditions that enhance IFNγ expression such as chronic periodontitis. These results suggest a complex relationship between genetics and defensin expression that may influence periodontal health and innate immune responses
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