MusE GAs FLOw and Wind (MEGAFLOW) IX. The impact of gas flows on the relations between the mass, star formation rate and metallicity of galaxies

We study the link between gas flow events and key galaxy scaling relations: the relations between star formation rate (SFR) and stellar mass (the main sequence, MS), gas metallicity and stellar mass (the mass-metallicity relation, MZR) and gas metallicity, stellar mass and SFR (the fundamental metallicity relation, FMR). Using all star-forming galaxies (SFGs) in the 22 MUSE fields of the MusE GAs FLOw and Wind (MEGAFLOW) survey, we derive the MS, MZR and FMR scaling relations for 385 SFGs with $M = 10^8 - 10^{11.5}$ $M_\odot$ at redshifts 0.35 < z < 0.85. Using the MUSE data and complementary X-Shooter spectra at 0.85 < z < 1.4, we determine the locations of 21 SFGs associated with inflowing or outflowing circumgalactic gas (i.e. with strong MgII absorption in background quasar spectra) relative to these scaling relations. Compared to a control sample of galaxies without gas flows (i.e., without MgII absorption within 70 kpc of the quasar), SFGs with inflow events (i.e., MgII absorption along the major axis) are preferentially located above the MS, while SFGs with ouflow events (i.e., MgII absorption along the minor axis) are preferentially more metal rich. Our observations support the scenario in which gas accretion increases the SFR while diluting the metal content and where circumgalactic outflows are found in more metal-rich galaxies.Comment: 13 pages, 8 figure

Towards Viral Genome Annotation Standards, Report from the 2010 NCBI Annotation Workshop

Improvements in DNA sequencing technologies portend a new era in virology and could possibly lead to a giant leap in our understanding of viral evolution and ecology. Yet, as viral genome sequences begin to fill the world’s biological databases, it is critically important to recognize that the scientific promise of this era is dependent on consistent and comprehensive genome annotation. With this in mind, the NCBI Genome Annotation Workshop recently hosted a study group tasked with developing sequence, function, and metadata annotation standards for viral genomes. This report describes the issues involved in viral genome annotation and reviews policy recommendations presented at the NCBI Annotation Workshop

Rietveld refinement of Sr5(AsO4)3Cl from high-resolution synchrotron data

The apatite-type compound, penta­strontium tris­[arsenate(V)] chloride, Sr5(AsO4)3Cl, has been synthesized by ion exchange at high temperature from a synthetic sample of mimetite [Pb5(AsO4)3Cl] with SrCO3 as a by-product. The results of the Rietveld refinement, based on high resolution synchrotron X-ray powder diffraction data, show that the title compound crystallizes in the same structure as other halogenoapatites with general formula A 5(YO4)3 X (A = divalent cation, Y = penta­valent cation, and X = F, Cl or Br) in the space group P63/m. The structure consists of isolated tetra­hedral AsO4 3− anions (the As atom and two O atoms have m symmetry), separated by two crystallographically independent Sr2+ cations that are located on mirror planes and threefold rotation axes, respectively. One Sr atom is coordinated by nine O atoms and the other by six. The chloride anions (site symmetry ) are at the 2a sites and are located in the channels of the structure

Western Indian Ocean marine and terrestrial records of climate variability: a review and new concepts on land-ocean interactions since AD 1660

We examine the relationship between three tropical and two subtropical western Indian Ocean coral oxygen isotope time series to surface air temperatures (SAT) and rainfall over India, tropical East Africa and southeast Africa. We review established relationships, provide new concepts with regard to distinct rainfall seasons, and mean annual temperatures. Tropical corals are coherent with SAT over western India and East Africa at interannual and multidecadal periodicities. The subtropical corals correlate with Southeast African SAT at periodicities of 16–30 years. The relationship between the coral records and land rainfall is more complex. Running correlations suggest varying strength of interannual teleconnections between the tropical coral oxygen isotope records and rainfall over equatorial East Africa. The relationship with rainfall over India changed in the 1970s. The subtropical oxygen isotope records are coherent with South African rainfall at interdecadal periodicities. Paleoclimatological reconstructions of land rainfall and SAT reveal that the inferred relationships generally hold during the last 350 years. Thus, the Indian Ocean corals prove invaluable for investigating land–ocean interactions during past centuries

Cored dark-matter profiles in z≃1 star forming galaxies

Galaxie

The MUSE extremely deep field: evidence for SFR-induced cores in dark-matter dominated galaxies at z ≃ 1

Galaxie

MYH7 p.(Arg1712Gln) is pathogenic founder variant causing hypertrophic cardiomyopathy with overall relatively delayed onset

Introduction: The MYH7 c.5135G &gt; A p.(Arg1712Gln) variant has been identified in several patients worldwide and is classified as pathogenic in the ClinVar database. We aimed to delineate its associated phenotype and evaluate a potential founder effect.Methods: We retrospectively collected clinical and genetic data of 22 probands and 74 family members from an international cohort.Results: In total, 53 individuals carried the MYH7 p.(Arg1712Gln) variant, of whom 38 (72%) were diagnosed with hypertrophic cardiomyopathy (HCM). Mean age at HCM diagnosis was 48.8 years (standard deviation: 18.1; range: 8–74). The clinical presentation ranged from asymptomatic HCM to arrhythmias (atrial fibrillation and malignant ventricular arrhythmias). Aborted sudden cardiac death (SCD) leading to the diagnosis of HCM occurred in one proband at the age of 68 years, and a family history of SCD was reported by 39% (5/13) probands. Neither heart failure deaths nor heart transplants were reported. Women had a generally later-onset disease, with 14% of female carriers diagnosed with HCM at age 50 years compared with 54% of male carriers. In both sexes, the disease was fully penetrant by age 75 years. Haplotypes were reconstructed for 35 patients and showed a founder effect in a subset of patients.Conclusion: MYH7 p.(Arg1712Gln) is a pathogenic founder variant with a consistent HCM phenotype that may present with delayed penetrance. This suggested that clinical follow-up should be pursued after the seventh decade in healthy carriers and that longer intervals between screening may be justified in healthy women &lt; 30 years.</p