269 research outputs found
The proton and electron radiation belts at geosynchronous orbit: Statistics and behavior during high‐speed stream‐driven storms
The outer proton radiation belt (OPRB) and outer electron radiation belt (OERB) at geosynchronous orbit are investigated using a reanalysis of the LANL CPA (Charged Particle Analyzer) 8‐satellite 2‐solar cycle energetic particle data set from 1976 to 1995. Statistics of the OPRB and the OERB are calculated, including local time and solar cycle trends. The number density of the OPRB is about 10 times higher than the OERB, but the 1 MeV proton flux is about 1000 times less than the 1 MeV electron flux because the proton energy spectrum is softer than the electron spectrum. Using a collection of 94 high‐speed stream‐driven storms in 1976–1995, the storm time evolutions of the OPRB and OERB are studied via superposed epoch analysis. The evolution of the OERB shows the familiar sequence (1) prestorm decay of density and flux, (2) early‐storm dropout of density and flux, (3) sudden recovery of density, and (4) steady storm time heating to high fluxes. The evolution of the OPRB shows a sudden enhancement of density and flux early in the storm. The absence of a proton dropout when there is an electron dropout is noted. The sudden recovery of the density of the OERB and the sudden density enhancement of the OPRB are both associated with the occurrence of a substorm during the early stage of the storm when the superdense plasma sheet produces a “strong stretching phase” of the storm. These storm time substorms are seen to inject electrons to 1 MeV and protons to beyond 1 MeV into geosynchronous orbit, directly producing a suddenly enhanced radiation belt population.Key PointsDuring high‐speed stream‐driven storms, the electron and proton radiation belts are directly enhanced by a single substormThe enhancing substorm occurs during the “strong stretching” phase of the storm caused by the superdense plasma sheetProton and electron injection to 1 MeV is seen for these strong stretching phase substormsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/133567/1/jgra52702.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/133567/2/jgra52702_am.pd
Field line distribution of mass density at geostationary orbit
The distribution of mass density along the field lines affects the ratios of toroidal (azimuthally oscillating) Alfv\u27{e}n frequencies, and given the ratios of these frequencies we can get information about that distribution. Here we assume the commonly used power law form for the field line distribution, rho_{m} = rho_{m,eq} ( L R_{E} /R )^alpha, where rho_{m,eq} is the value of the mass density rho_{m} at the magnetic equator, L is the L shell, R_{E} is the Earth\u27s radius, R is the geocentric distance to a point on the field line, and alpha is the power law coefficient. Positive values of alpha indicate that rho_{m} increases away from the magnetic equator, zero value indicates that rho_{m} is constant along the magnetic field line, and negative alpha indicates that there is a local peak in rho_{m} at the magnetic equator. Using 12 years of observations of toroidal Alfven frequencies by the Geostationary Operational Environmental Satellites (GOES), we study the typical dependence of inferred values of alpha on the magnetic local time (MLT), the phase of the solar cycle as specified by the F10.7 extreme ultraviolet solar flux, and geomagnetic activity as specified by the auroral electrojet (AE) index. Over the mostly dayside range of the observations, we find that alpha decreases with respect to increasing MLT and F10.7, but increases with respect to increasing AE. We develop a formula that depends on all three parameters, alpha_{3Dmodel} = 2.2 + 1.3 cos(MLT 15 degrees) + 0.0026 {AE} cos((MLT-0.8) 15 degrees) + 2.1 10^{-5} {AE} {F10.7} - 0.010 {F10.7},\r\nthat models the binned values of alpha within a standard deviation of 0.3. While we do not yet have a complete theoretical understanding of why alpha should depend on these parameters in such a way, we do make some observations and speculations about the causes. At least part of the dependence is related to that of rho_{m,eq}; higher alpha, corresponding to steeper variation with respect to MLAT, occurs when rho_{m,eq} is lower
Study of EMIC wave excitation using direct ion measurements
With data from Van Allen Probes, we investigate electromagnetic ion cyclotron (EMIC) wave excitation using simultaneously observed ion distributions. Strong He band waves occurred while the spacecraft was moving through an enhanced density region. We extract from helium, oxygen, proton, and electron mass spectrometer measurement the velocity distributions of warm heavy ions as well as anisotropic energetic protons that drive wave growth through the ion cyclotron instability. Fitting the measured ion fluxes to multiple sinm-type distribution functions, we find that the observed ions make up about 15% of the total ions, but about 85% of them are still missing. By making legitimate estimates of the unseen cold (below ∼2 eV) ion composition from cutoff frequencies suggested by the observed wave spectrum, a series of linear instability analyses and hybrid simulations are carried out. The simulated waves generally vary as predicted by linear theory. They are more sensitive to the cold O+ concentration than the cold He+ concentration. Increasing the cold O+ concentration weakens the He band waves but enhances the O band waves. Finally, the exact cold ion composition is suggested to be in a range when the simulated wave spectrum best matches the observed one
Home-based Circuit Training and Community Walking for Intermittent Claudication
Background: Supervised exercise training is recommended for people with peripheral artery disease (PAD), yet it remains underutilized. Home-based exercise programs (HBEPs) are a potential alternative. The aim of this study was to assess the feasibility of conducting a full scale trial of a 12-week HBEP for people living with symptomatic PAD. Methods: In a randomized feasibility trial, patients with intermittent claudication were allocated to either an HBEP or a nonexercise control. The HBEP group was given a Fitbit to use during a 12-week exercise program comprising of personalized step goals and a resistance-based circuit to be undertaken at home twice weekly. The primary outcome was feasibility, assessed via eligibility, recruitment, attrition, tolerability, and adherence. Acceptability was assessed via semistructured interviews. Secondary analysis was undertaken to determine the feasibility of collecting clinical outcome data. Results: 188 people were screened, 133 were eligible (70.7%), 30 were recruited (22.6%) and one withdrew (3.33%). Mean adherence to the daily step goal was 53.5% (range = 29.8–90.5%), and 58.6% of prescribed circuits were completed of which 56.4% were at the desired intensity. Six adverse events were recorded, 3 of which were related to study involvement. No significant differences were observed in exploratory outcomes. Small clinically important differences were seen in walking speed and pain-free treadmill walking distance which should be confirmed or refuted in a larger trial. Conclusions: The HBEP was feasible and well tolerated, with successful recruitment and minimal attrition. The intervention was acceptable, with walking seen as more enjoyable than circuit exercise. The WALKSTRONG program may be suitable for those who will not, or cannot, take part in supervised exercise outside of the home.</p
Documenting and harnessing the biological potential of molecules in Distributed Drug Discovery (D3) virtual catalogs
Virtual molecular catalogs have limited utility if member compounds are (i) difficult to synthesize or (ii) unlikely to have biological activity. The Distributed Drug Discovery (D3) program addresses the synthesis challenge by providing scientists with a free virtual D3 catalog of 73,024 easy-to-synthesize N-acyl unnatural α-amino acids, their methyl esters, and primary amides. The remaining challenge is to document and exploit the bioactivity potential of these compounds. In the current work, a search process is described that retrospectively identifies all virtual D3 compounds classified as bioactive hits in PubChem-cataloged experimental assays. The results provide insight into the broad range of drug-target classes amenable to inhibition and/or agonism by D3-accessible molecules. To encourage computer-aided drug discovery centered on these compounds, a publicly available virtual database of D3 molecules prepared for use with popular computer docking programs is also presented
Structure of the Current Sheet in the 11 July 2017 Electron Diffusion Region Event.
The structure of the current sheet along the Magnetospheric Multiscale (MMS) orbit is examined during the 11 July 2017 Electron Diffusion Region (EDR) event. The location of MMS relative to the X-line is deduced and used to obtain the spatial changes in the electron parameters. The electron velocity gradient values are used to estimate the reconnection electric field sustained by nongyrotropic pressure. It is shown that the observations are consistent with theoretical expectations for an inner EDR in 2-D reconnection. That is, the magnetic field gradient scale, where the electric field due to electron nongyrotropic pressure dominates, is comparable to the gyroscale of the thermal electrons at the edge of the inner EDR. Our approximation of the MMS observations using a steady state, quasi-2-D, tailward retreating X-line was valid only for about 1.4 s. This suggests that the inner EDR is localized; that is, electron outflow jet braking takes place within an ion inertia scale from the X-line. The existence of multiple events or current sheet processes outside the EDR may play an important role in the geometry of reconnection in the near-Earth magnetotail
Turbulence properties and kinetic signatures of electron in Kelvin-Helmholtz waves during a geomagnetic storm
We present a comprehensive study of Magnetospheric Multiscale (MMS)
spacecraft encounter with KHI during a geomagnetic storm, focusing on
elucidating key turbulence properties and reconnection signatures observed at
the edges of KH vortices. The spectral slope for electric field stays
approximately constant for frequencies below the ion cyclotron frequency and
exhibits a break around the lower hybrid frequency, indicating wave activity.
Furthermore, MMS observes a current sheet accompanied by intense electron jets
and features consistent with strong guide-field asymmetric reconnection across
the magnetopause. Substantial agyrotropy (by a factor of 10) in electron
distribution functions is observed in the reconnecting current sheet and at the
edges of KH. Our observation presents a multi-scale view into KH turbulence
under strongly driven conditions and into the dynamics occurring at electron
dissipation scales.Comment: 10 pages, including 4 figure
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