Hamiltonian formulation of nonAbelian noncommutative gauge theories

We implement the Hamiltonian treatment of a nonAbelian noncommutative gauge theory, considering with some detail the algebraic structure of the noncommutative symmetry group. The first class constraints and Hamiltonian are obtained and their algebra derived, as well as the form of the gauge invariance they impose on the first order action.Comment: enlarged version, 7 pages, RevTe

The Hamiltonian BRST quantization of a noncommutative nonabelian gauge theory and its Seiberg-Witten map

We consider the Hamiltonian BRST quantization of a noncommutative non abelian gauge theory. The Seiberg-Witten map of all phase-space variables, including multipliers, ghosts and their momenta, is given in first order in the noncommutative parameter $\theta$. We show that there exists a complete consistence between the gauge structures of the original and of the mapped theories, derived in a canonical way, once we appropriately choose the map solutions.Comment: 10 pages, Latex. Address adde

Acute exposition to Roundup Transorb® induces systemic oxidative stress and alterations in the expression of newly sequenced genes in silverside fish (Odontesthes humensis)

Roundup Transorb® (RDT) is a glyphosate-based herbicide commonly used in agricultural practices worldwide. This herbicide exerts negative effects on the aquatic ecosystem and affects bioenergetic and detoxification pathways, oxidative stress, and cell damage in marine organisms. These effects might also occur at the transcriptional level; however, the expression of genes associated with oxidative stress has not been studied well. Odontesthes humensis is a native Brazilian aquatic species naturally distributed in the habitats affected by pesticides, including Roundup Transorb® (RDT). This study evaluated the toxic effects of short-term exposure to RDT on O. humensis. Moreover, the genes related to oxidative stress were sequenced and characterized, and their expressions in the gills, hepatopancreas, kidneys, and brain of the fish were quantified by quantitative reverse transcription-polymerase chain reaction. The animals were exposed to two environmentally relevant concentrations of RDT (2.07 and 3.68 mg L−1) for 24 h. Lipid peroxidation, reactive oxygen species (ROS), DNA damage, and apoptosis in erythrocytes were quantified by flow cytometry. The expression of the target genes was modulated in most tissues in the presence of the highest tested concentration of RDT. In erythrocytes, the levels of lipid peroxidation, ROS, and DNA damage were increased in the presence of both the concentrations of RDT, whereas cell apoptosis was increased in the group exposed to 3.68 mg L−1 RDT. In conclusion, acute exposure to RDT caused oxidative stress in the fish, induced negative effects on cells, and modulated the expression of genes related to the enzymatic antioxidant system in O. humensis.Fil: Martins, Amanda Weege S.. Universidade Federal de Pelotas; BrasilFil: Silveira, Tony L. R.. Universidade Federal de Pelotas; Brasil. Universidade Federal do Rio Grande; BrasilFil: Remião, Mariana H.. Universidade Federal de Pelotas; BrasilFil: Domingues, William Borges. Universidade Federal de Pelotas; BrasilFil: Dellagostin, Eduardo N.. Universidade Federal de Pelotas; BrasilFil: Varela Junior, Antônio Sergio. Universidade Federal do Rio Grande; Brasil. Universidade Federal de Pelotas; BrasilFil: Corcini, Carine D.. Universidade Federal de Pelotas; BrasilFil: Costa, Patrícia G.. Universidade Federal do Rio Grande; BrasilFil: Bianchini, Adalto. Universidade Federal do Rio Grande; BrasilFil: Somoza, Gustavo Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús). Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús); ArgentinaFil: Robaldo, Ricardo B.. Universidade Federal de Pelotas; BrasilFil: Campos, Vinicius Farias. Universidade Federal de Pelotas; Brasi

Análise por infravermelho e citotoxicidade das micropartículas de óleos essenciais de Ocimum Gratissimum L. E Cymbopogon Citratus (D.C.) stapf.

Título em inglês: Infrared And Cytotoxicity Analysis Of Microparticles Of Essential Oils Of Ocimum Gratissimum L. And Cymbopogon Citratus (D.C.) Stapf

Vulnerable marine ecosystems and biological features of Gazul mud volcano (Gulf of Cádiz): A contribution towards a potential "Gulf of Cádiz" EBSA

The Gulf of Cádiz (GoC) represents an area of socioeconomic and scientific importance for oceanographic, geological and biological processes. An interesting feature of the GoC is the presence of a large amount of mud volcanoes (MVs) and diapirs that display different seepage, seabed types, oceanographic settings and biological communities. Detailed exploration of some MVs is still needed for detecting Vulnerable Marine ecosystems (VMEs) that seem to be rare in other areas of the GoC, improving the current knowledge on its biodiversity and ecological attributes. During different expeditions (MEDWAVES-ATLAS, INDEMARES-CHICA 0610 & 0412 and ISUNEPCA 0616) carried out in different years, biological samples and videos were obtained in Gazul MV (Spanish Margin of the GoC). The study of those samples and videos has revealed the presence of several ecologically important VMEs (e.g. 3 species of reef framework-forming corals, coral gardens including solitary scleractinians, gorgonians and antipatharians, as well as deep-sea sponge aggregations and chemosynthesis-related structures) and a large number of species occurring in this MV, including new records for the European margin, threatened species and non-previously described species. The combination of different environmental and anthropogenic factors allowed the present-day persistence of these VMEs in the GoC. Some of Gazul MV biological and ecological attributes fit several criteria of the Convention on Biological Diversity for EBSA description (e.g. 1,3,4,6) that, together with those of other areas of the GoC, may contribute to the future potential nomination of an EBSA in this area of the NE Atlantic

Environmental, fishing and benthic linkage in the mud volcano field of the Spanish margin of the Gulf of Cádiz

The Gulf of Cadiz is located in the boundary of two lithospheric plates, this tectonic activity promote fluid rich hydrocarbon emissions from subsurface reservoirs and the formation of several mud volcanoes. The seabed and sedimentological heterogeneity, the complex oceanographic circulation, and the low fishing activity in certain areas may promote high biodiversity and complex habitats (habitat 1170 and 1180, Natura 2000). Environmental variables (fishing activity, substrate types, near bottom currents) and fauna collected with beam-trawl have been compared for several mud volcanoes and adjacent bottoms in order to understand the spatial distribution of both habitats and environmental/anthropogenic variables. The faunistic samples yielded high abundances, biomass and species richness in Gazul, Pipoca and Chica but low ones in Anastasya. In relation to environmental variables and fisheries activity, there is a strong correlation with the substrate type, depth, salinity and near-bottom current as primary variables influencing the distribution of habitats of different mud volcanoes. In this context, high species richness, abundance and biomass was found in areas with authigenic carbonates, coarse sediments, high near-bottom current speed, low salinities and low fishing activity.Versión del edito

Zeolite structures loading with an anticancer compound as drug delivery systems

The authors are thankful to Dr. A. S. Azevedo for collecting the powder diffraction data.Two different structures of zeolites, faujasite (FAU) and Linde type A (LTA), were studied to investigate their suitability for drug delivery systems (DDS). The zeolites in the sodium form (NaY and NaA) were used as hosts for encapsulation of α-cyano-4- hydroxycinnamic acid (CHC). CHC, an experimental anticancer drug, was encapsulated in both zeolites by diffusion in liquid phase. These new drug delivery systems, CHC@zeolite, were characterized by spectroscopic techniques (FTIR, 1H NMR, 13C and 27Al solidstate MAS NMR, and UV−vis), chemical analysis, powder X-ray diffraction (XRD) and scanning electron microscopy (SEM). The effect of the zeolites and CHC@zeolite drug deliveries on HCT-15 human colon carcinoma cell line viability was evaluated. Both zeolites alone revealed no toxicity to HCT-15 cancer cells. Importantly, CHC@zeolite exhibit an inhibition of cell viability up to 585-fold, when compared to the non-encapsulated drug. These results indicate the potential of the zeolites for drug loading and delivery into cancer cells to induce cell deathO.M. and R.A. are recipients of fellowships (SFRH/BD/36463/2007, SFRH/BI/51118/2010) from Fundação para a Ciência e a Tecnologia (FCT, Portugal). This work was supported by the FCT projects refs PEst-C/ QUI/UI0686/2011, PEst-C/CTM/LA0011/2011, and PTDC/ SAU-FCF/104347/2008, under the scope of “Programa Operacional Temático Factores de Competitividade” (COMPETE) of “Quadro Comunitário de Apoio III” and cofinanced by Fundo Comunitário Europeu FEDER, and the Centre of Chemistry and Life and Health Sciences Research Institute (University of Minho, Portugal)

Classification of schizophrenic traits in transcriptions of audio spectra from patient literature: artificial intelligence models enhanced by geometric properties

Schizophrenia is a severe mental illness that affects approximately 1% of the global population and presents significant challenges for patients, families, and healthcare professionals. Characterized by symptoms such as delusions, hallucinations, disorganized speech or behavior, and cognitive impairment, this condition has an early onset and chronic trajectory, making it a debilitating challenge. Schizophrenia also imposes a substantial burden on society, exacerbated by the stigma associated with mental disorders. Technological advancements, such as computerized semantic, linguistic, and acoustic analyses, are revolutionizing the understanding and assessment of communication alterations, a significant aspect in various severe mental illnesses. Early and accurate diagnosis is crucial for improving prognosis and implementing appropriate treatments. In this context, the advancement of Artificial Intelligence (AI) has provided new perspectives for the treatment of schizophrenia, with machine learning techniques and natural language processing allowing a more detailed analysis of clinical, neurological, and behavioral data sets. The present article aims to present a proposal for computational models for the identification of schizophrenic traits in texts.  The database used in this article was created with 139 excerpts of patients' speeches reported in the book “Memories of My Nervous Disease” by German judge Daniel Paul Schreber, classifying them into three categories: 1 - schizophrenic, 2 - with schizophrenic traits and 3 - without any relation to the disorder. Of these speeches, 104 were used for training the models and the others 35 for validation.Three classification models were implemented using features based on geometric properties of graphs (number of vertices, number of cycles, girth, vertex of maximum degree, maximum clique size) and text entropy. Promising results were observed in the classification, with the Decision Tree-based model [1] achieving 100% accuracy, the KNN- k-Nearest Neighbor model observed with 62.8% accuracy, and the 'centrality-based' model with 59% precision. The high precision rates, observed when geometric properties are incorporated into Artificial Intelligence Models, suggest that the models can be improved to the point of capturing the language deviation traits that are indicative of schizophrenic disorders. In summary, this study paves the way for significant advances in the use of geometric properties in the field of psychiatry, offering a new data-based approach to the understanding and therapy of schizophrenia