73 research outputs found

    Actinomyces bouchesdurhonensis sp. nov. and Actinomyces mediterranea sp. nov., isolated from human stomach and duodenum

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    We propose here the main characteristics of the new bacteria Actinomyces bouchesdurhonensis strain Marseille-P2825 (CSUR P2825) isolated from a gastric liquid sample of a 60-year-old man and Actinomyces mediterranea strain Marseille-P3257 (CSUR P3257) isolated from a duodenal liquid sample of a 76-year-old woman. Keywords: Culturomics, Taxonogenomics, Gut microbiota, Actinomyces bouchesdurhonensis, Actinomyces mediterrane

    Peptoniphilus duodeni sp. nov., a new bacterial species identified in human duodenum

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    We present here the main characteristics of Peptoniphilus duodeni strain Marseille-P2932 (= CSUR P2932, = DSM 103346) that was isolated from the duodenum of a 60-year-old male. Keywords: Culturomics, Taxonogenomics, Gut microbiota, Human gut, Peptoniphilus duoden

    Chagas disease knocks on our door : A cross-sectional study among Latin American immigrants in Milan, Italy

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    Objectives: We aimed to assess the prevalence and risk factors for Chagas disease (CD) in Latin American immigrants and to evaluate the accuracy of diagnostic tests. Moreover, we offered to all positive subjects a complete free-of-charge clinical/instrumental evaluation as well as benznidazole treatment in order to stage the disease and verify drug tolerability. Methods: A cross-sectional survey of CD among Latin Americans living in Milan and its metropolitan area was conducted between July 2013 and July 2014. Blood samples were tested for serologic evidence of CD together with a questionnaire covering demographic and clinical-epidemiological information. Results: Forty-eight (9.6%) of the 501 tested subjects were conclusively diagnosed as having CD. The highest prevalence of CD was among those from Bolivia (43/169, 25.4%) and El Salvador (4/68, 5.9%). Older age (adjusted odds ratio (aOR)] 1.05, p =0.004), a Bolivian origin (aOR 8.80; p =0.003), being born in the department of Santa Cruz (aOR 3.72, p =0.047), having lived in mud houses (aOR 2.68; p =0.019), and having an affected relative (aOR 12.77, p =0.001) were independently associated with CD. The ARCHITECT Chagas test showed the highest sensitivity (100%) and specificity (99.8%). Twenty-nine of the subjects with CD (60.4%) underwent disease staging, 10 of whom (35.7%) showed cardiac and/or digestive involvement. Benznidazole treatment was associated with high frequency of adverse reactions (19/27, 70.4%) and permanent discontinuation (8/27, 29.6%). Conclusions: CD is highly prevalent among Bolivians and Salvadorans living in Milan. Regions with a large Latin American immigrant population should implement programmes of active detection and treatment

    Other Helicobacters, gastric and gut microbiota

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    The current article is a review of the most important and relevant literature published in 2016 and early 2017 on non-Helicobacter pylori Helicobacter infections in humans and animals, as well as interactions between H. pylori and the microbiota of the stomach and other organs. Some putative new Helicobacter species were identified in sea otters, wild boars, dogs, and mice. Many cases of Helicobacter fennelliae and Helicobacter cinaedi infection have been reported in humans, mostly in immunocompromised patients. Mouse models have been used frequently as a model to investigate human Helicobacter infection, although some studies have investigated the pathogenesis of Helicobacters in their natural host, as was the case for Helicobacter suis infection in pigs. Our understanding of both the gastric and gut microbiome has made progress and, in addition, interactions between H. pylori and the microbiome were demonstrated to go beyond the stomach. Some new approaches of preventing Helicobacter infection or its related pathologies were investigated and, in this respect, the probiotic properties of Saccharomyces, Lactobacillus and Bifidobacterium spp. were confirmed

    'Colibacter massiliensis' gen. nov., sp. nov., a new bacterial species isolated from human left colon.

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    International audienceWe present here the main characteristics of the strain Marseille-P2911 (= CSUR P2911 = DSMZ 103304), a bacterial species isolated from the left colon liquid sample of a 60-year-old man

    Draft Genome Sequence of Blautia faecis Strain Marseille-P328, Isolated from the Human Ascending Colon.

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    International audienceBlautia faecis strain Marseille P328 was isolated from the ascending colon of a French patient. We sequenced the 4.45-Mb genome of the strain and compared itwith that of other species of the Blautia genus
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