Revisão do gênero monotípico Chilelimnophila Alexander (Diptera: Tipulomorpha: Limoniidae)

The Chilean species Chilelimnophila lyra (Alexander, 1952), the only included species in the genus Chilelimnophila Alexander, 1968, is redescribed on the basis of new available material from adjacencies of the type locality and other areas. Misinterpretations from the original description are corrected. Adult anatomical structures are described and illustrated in detail, including information on the previously unknown female. Better grounds for the recognition of the taxon are provided.Chilelimnophila lyra (Alexander, 1952), a única espécie do gênero Chilelimnophila Alexander, 1968, do Chile, é redescrita com base em novos espécimes de áreas próximas à localidade tipo e outras áreas. Interpretações incorretas da descrição original são corrigidas. As estruturas anatômicas do imago são descritas e ilustradas em detalhe, incluindo informações sobre as fêmeas, até então desconhecidas. Melhores subsídios para o reconhecimento do táxon são fornecidos

Revisão do gênero monotípico Chilelimnophila Alexander (Diptera: Tipulomorpha: Limoniidae)

The Chilean species Chilelimnophila lyra (Alexander, 1952), the only included species in the genus Chilelimnophila Alexander, 1968, is redescribed on the basis of new available material from adjacencies of the type locality and other areas. Misinterpretations from the original description are corrected. Adult anatomical structures are described and illustrated in detail, including information on the previously unknown female. Better grounds for the recognition of the taxon are provided.Chilelimnophila lyra (Alexander, 1952), a única espécie do gênero Chilelimnophila Alexander, 1968, do Chile, é redescrita com base em novos espécimes de áreas próximas à localidade tipo e outras áreas. Interpretações incorretas da descrição original são corrigidas. As estruturas anatômicas do imago são descritas e ilustradas em detalhe, incluindo informações sobre as fêmeas, até então desconhecidas. Melhores subsídios para o reconhecimento do táxon são fornecidos

Design, poesia e loucura : projeto editorial para livro de poemas de Stela do Patrocínio

Este trabalho contém o registro da pesquisa teórica e prática referente à execução do Trabalho de Conclusão de Curso (TCC) em Design Visual pela Universidade Federal do Rio Grande do Sul (UFRGS), realizado como pré-requisito para obtenção do título de designer. Na primeira etapa, o trabalho delimita o desenvolvimento de um projeto editorial para o livro “Reino dos bichos e dos animais é o meu nome”, da poeta Stela do Patrocínio, a partir de reflexões teóricas oriundas das especificidades biográficas da autora (uma mulher, negra, que viveu internada em um manicômio durante mais de trinta anos). Nessa etapa, também são delineadas as diretrizes projetuais a serem cumpridas na segunda fase do projeto, tanto no que concerne aos elementos simbólicos quanto aos elementos práticos de realização física do livro. A segunda etapa, enfim, contém o registro da execução prática do projeto gráfico do livro e das soluções de design obtidas, culminando com a apresentação do protótipo finalizado.This study registers theoretical and practical research regarding the execution of a conclusion project, produced by the author as a requisite for obtaining the title of bachelor in the Visual Design course of Universidade Federal do Rio Grande do Sul (UFRGS). In its first part, the study contains the delimitation of an editorial project for the book “Reino dos bichos e dos animais é o meu nome”, by the author Stela do Patrocínio, based on theoretical observations of her specific biography (since she was a black woman who was held in an asylum for more than 30 years. In this part, as well, the guidelines for the second phase are defined, in what concerns the symbolical elements and the practical elements related to the physical production of the book. The second part registers the execution of the graphic project and its design solutions, culminating in the presentation of the completed prototype

Quatro “Sonetos sobre a morte”, de Jean de Sponde

In this work, I present four “Sonnets on Death”, written by the French poet Jean de Sponde (1557-1595) – those numbered as 1, 2, 5 and 6 – which I translated to Brazilian Portuguese based on the perspective of poetic translation. Here I’m calling poetic translation the act of translation which is interested not only in conveying meaning, but in being a poiéin (as the Greeks would call it), a fabrication that may respond to the complex entity of a poem and its effects, considering both its form and content. In addition, I also include by way of introduction short biographical notes about this rather unknown poet.Neste trabalho, apresento as traduções de quatro "Sonetos sobre a morte", de Jean de Sponde (1557-1595) – os de número 1, 2, 5 e 6 – para o português brasileiro, a partir da perspectiva da tradução poética. Chamo aqui de tradução poética aquele ato tradutório cujo objetivo não é somente transmitir um significado, mas sobretudo ser uma poiéin (como os Gregos diriam), uma fabricação ou um fazer que corresponda à totalidade do poema e seus efeitos, em seu complexo fundo-e-forma. Apresento ainda, à guisa de introdução, algumas rápidas anotações biográficas a respeito deste poeta desconhecido. Neste trabalho, apresento as traduções de quatro "Sonetos sobre a morte", de Jean de Sponde (1949), oe de número 1, 2, 5 e 6, para o português brasileiro, a partir da perspectiva da tradução poética

Análise da capacidade funcional em idosas praticantes de hidroginástica / Analysis of functional capacity in older hydroginastic practice

Introdução: De acordo com o IBGE o número de idosos aumenta muito a cada dia chegando em 2018 a superar a marca dos 30,2 milhões de idosos com idade igual ou acima de 60 anos da população brasileira. Com o crescimento constante desses índices a procura da terceira idade pelas práticas de atividades físicas, também aumenta. A hidroginástica é uma atividade muito procurado e que pode propiciar grandes benefícios para seus praticantes. Objetivo: Analisar a capacidade funcional de idosos praticantes de hidroginástica no Programa de Atividades Físicas e Esportivas (PROAFE) na cidade de Gurupi no Tocantins.  Material e Método: Trata-se de um estudo descritivo, quantitativo, composto por uma amostragem de 19 idosas. A análise estatística foi realizada através do teste T-Student, admitindo seu nível de significância p<0,05. Resultados: A capacidade funcional obtida foram: C10M e LPDV com escore “fraco”, LCLC e VTC com escore “muito bom” e LPS “regular”, obtendo o IG “bom”

Evaluation of microvessel density and p53 expression in pancreatic adenocarcinoma

OBJECTIVE: To evaluate the prognostic significance of microvessel density and p53 expression in pancreatic cancer. METHODS: Between 2008 and 2012, 49 patients with pancreatic adenocarcinoma underwent resection with curative intention. The resected specimens were immunohistochemically stained with anti-p53 and anti-CD34 antibodies. Microvessel density was assessed by counting vessels within ten areas of each tumoral section a highpower microscope. RESULTS: The microvessel density ranged from 21.2 to 54.2 vessels/mm2. Positive nuclear staining for p53 was found in 20 patients (40.6%). The overall median survival rate after resection was 24.1 months and there were no differences in survival rates related to microvessel density or p53 positivity. Microvessel density was associated with tumor diameter greater than 3.0 cm and with R0 resection failure. CONCLUSIONS: Microvessel density was associated with R1 resection and with larger tumors. p53 expression was not correlated with intratumoral microvessel density in pancreatic adenocarcinoma

High level of serovar copenhageni detection in dog sera from Patrocínio, MG, Brazil

T This study aimed to evaluate the occurrence of canine leptospirosis and the possible risk factors associated with the disease in the municipality of Patrocínio, MG, Brazil. A cross-sectional observational study was carried out from July through August 2017.  The municipality was divided into four regions (north, south, east and west) and a predefined number of neighborhoods (25) were randomly sampled in each region. Samples of blood serum were collected from 241 domiciled male and female dogs of different breeds and ages. To investigate the risk factors for canine leptospirosis, the owners of the animals were asked to fill out an epidemiological questionnaire. The following factors were evaluated: breed, sex, age, presence of rodents, type of diet, access to the street, vaccination, presence of flooded areas, and educational level of the owners. Blood serum samples were evaluated by the Microscopic Agglutination Test (MAT), using a collection of 24 live antigens. Of the 241 dogs evaluated, 32 (13.2%) were reactive. The most frequent serovars were: Copenhageni (37.5%) and Canicola (21.8%), followed by Icterohaemorrhagiae and Grippotyphosa (12.5%), Pomona, Tarassovi and Butembo (9.3%) and Hardjo (6.2%). The presence of canine leptospirosis was associated with purebred dogs (OR=0.3059 [95% CI: 0.1430 – 0.6547]) and vaccination (OR=2.581 [95% CI: 1.198 – 5.563]). It was concluded that some dogs in the municipality of Patrocínio, MG have anti-Leptospira spp. antibodies and that the serovars most frequently identified were Copenhageni (37.5%) and Canicola (21.8%). Pure breeds and vaccination were factors associated with the prevalence of infection

A Vaccine Encoding Conserved Promiscuous HIV CD4 Epitopes Induces Broad T Cell Responses in Mice Transgenic to Multiple Common HLA Class II Molecules

Current HIV vaccine approaches are focused on immunogens encoding whole HIV antigenic proteins that mainly elicit cytotoxic CD8+ responses. Mounting evidence points toward a critical role for CD4+ T cells in the control of immunodeficiency virus replication, probably due to cognate help. Vaccine-induced CD4+ T cell responses might, therefore, have a protective effect in HIV replication. In addition, successful vaccines may have to elicit responses to multiple epitopes in a high proportion of vaccinees, to match the highly variable circulating strains of HIV. Using rational vaccine design, we developed a DNA vaccine encoding 18 algorithm-selected conserved, “promiscuous” (multiple HLA-DR-binding) B-subtype HIV CD4 epitopes - previously found to be frequently recognized by HIV-infected patients. We assessed the ability of the vaccine to induce broad T cell responses in the context of multiple HLA class II molecules using different strains of HLA class II- transgenic mice (-DR2, -DR4, -DQ6 and -DQ8). Mice displayed CD4+ and CD8+ T cell responses of significant breadth and magnitude, and 16 out of the 18 encoded epitopes were recognized. By virtue of inducing broad responses against conserved CD4+ T cell epitopes that can be recognized in the context of widely diverse, common HLA class II alleles, this vaccine concept may cope both with HIV genetic variability and increased population coverage. The vaccine may thus be a source of cognate help for HIV-specific CD8+ T cells elicited by conventional immunogens, in a wide proportion of vaccinees

Papel do córtex parietal posterior na realização de uma tarefa sensório-motora

This study aimed to elucidate electrophysiological and cortical mechanisms involved in anticipatory actions when individuals had to catch balls in free drop; specifically through quantitative electroencephalography (qEEG) alpha absolute power changes. The sample was composed for 23 health subjects, both sexes, with ages varying between 25 and 40 years, absence of mental and physical illness, right handed and don't make use of any psychoactive or psychotropic substance at the time of the study. The experiment consisted of a task of catching balls in free drop. The three-way ANOVA analysis demonstrated an interaction between moment and position factors in left parietal posterior cortex (PPC) (p=0.001). Through the experimental task employed, this area demonstrated a differentiated activity involving expectation, planning and preparedness in the ball's drop task.O estudo tentou elucidar mecanismos eletrofisiológicos e corticais envolvidos em ações antecipatórias quando os sujeitos testados tiveram que apreender bolas em queda livre; especificamente através de mudanças na potência absoluta na banda alfa da eletrencefalografia quantitativa (EEGq). A amostra foi composta por 23 sujeitos sadios, ambos os sexos, idade entre variando entre 25 e 40 anos, sem comprometimento físico e mental, destros, e não fazer uso de nenhuma substância psicoativa ou psicotrópicos até o momento do estudo. O experimento consistiu de uma tarefa de apreensão de bolas em queda livre. A análise three-way ANOVA demonstrou uma interação entre os fatores momento e posição no córtex parietal posterior (CPP) esquerdo (p=0,001). Através da tarefa experimental empregada, esta área demonstrou uma atividade diferenciada envolvendo expectativa, planejamento e prontidão na tarefa de queda de bolas

Periodontal diseases: is it possible to prevent them? A populational and individual approach

Periodontal diseases are infectious inflammatory chronic diseases of a multifactorial nature. They are primarily caused by dysbiotic ecological changes in dental biofilm, which may be influenced by risk factors. The prevention of periodontal diseases may involve different strategies focused on reducing distal, intermediate, and proximal risk factors at both the population and individual levels. Effective prevention depends on interdisciplinary and common risk factor approaches. Also, patient-centered preventive models are more effective than professional-centered models in the management of periodontal diseases. Regular and periodic control of dental biofilm is an essential measure for the different levels of prevention of periodontal diseases. The effectiveness of periodontal disease prevention largely depends on positive modifications of behavior, knowledge, health literacy, patient empowerment, motivation, and compliance.publishedVersio