6 research outputs found

    Single nucleotide polymorphism genomic arrays analysis of t(8;21) acute myeloid leukemia cells

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    Translocation of chromosomes 8 and 21, t(8;21), resulting in the AML1-ETO fusion gene, is associated with acute myeloid leukemia (AML). The findings of this study indicate that genomic alterations and KIT-D816 mutation confer a poor prognosis in t(8;21) AML patients
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