Salvia virgata L. Leaves Extract: Qualitative and Quantitative Phenolic Compounds and Antioxidant Activity

Plants' materials are a rich source of phenolic compounds (flavonoids, tannins and anthocyanin) that are the most important natural antioxidants. Antioxidants in the diet are very important for health and protected the body for oxidative stress. This research has been done for measurement of quantitative and qualitative of phenolic compounds and antioxidant activity of Salvia virgata L. as an alternative to synthesis antioxidants. In this work, the phytochemical study was performed on Salvia virgata L., and the amount of phenol and flavonoids were measured from three extract using spectrophotometric UV method. The antioxidant activity of the different extract was evaluated in different concentrations using (DPPH). Data analysis and variance analysis were done with SPSS software 16th version The results showed that total phenolic compounds of aqueous, ethanol and methanol extracts were 35.5, 34, 32.5 GAE/g dry samples respectively, and the total flavonoids content of aqueous, ethanol and methanol extracts were 28.12, 23.40, 26.50 mgQE/g dry sample The  concentration  inhibition of 50% ethereal extract (IC50) =5.4±0.6 and phytochemical results indicate the presence of flavonoids, tannins and anthocyanin in the extract. The results showed that the different extracts are rich withphenolic compounds and also present a high level of antioxidant properties, therefore, Salvia virgata L. could be used as a source of antioxidant compounds in food and as medicinal plant

Outsourcing of human resources and its impact on the executive performance of companies affiliated to the Ministry of Health

Background: The emergence of global markets and competitors and new competitive strategies based on quality, speed and cooperation agreements have forced managers to adopt new management strategies. The present study aimed to provide a model of human resource outsourcing and its impact on the executive performance of companies affiliated to the Ministry of Health. Methods: The research steps were: to determine the components of human resources outsourcing in the Ministry of Health, to determine the causes of the dynamics of the human resources outsourcing model in the Ministry of Health, and to determine the causal relationships of the components of human resources outsourcing in the Ministry of Health, respectively. First, a level, flow map and model simulation were developed. Then, the model test was performed based on the model validation tests, and finally, policies were designed and evaluated. Results: As strategic factors increase, management factors improve. Social factors lead to the growth of strategic factors. The growth of service-related factors improves technology and quality, and leads to the growth of more economic factors, which ultimately improves the outsourcing of human resources. Conclusion: Outsourcing, which is nowadays considered as a method of assigning a part of the work to the outside of the organization on a contract basis, like any other method that can be useful, might have many disadvantages if it does not have defined conditions and standards

Absence of isolated critical points with nonstandard critical exponents in the four-dimensional regularization of Lovelock gravity

Hyperbolic vacuum black holes in Lovelock gravity theories of odd order $N$ are known to have the so-called isolated critical points with nonstandard critical exponents (as $\alpha = 0$, $\beta = 1$, $\gamma = N-1$, and $\delta = N$), different from those of mean-field critical exponents (with $\alpha = 0$, $\beta = 1/2$, $\gamma = 1$, and $\delta = 3$). Motivated by this important observation, here, we explore the consequences of taking the $D \to 4$ limit of Lovelock gravity and the possibility of finding nonstandard critical exponents associated with isolated critical points in four-dimensions by use of the four-dimensional regularization, recently proposed by Glavan and Lin \cite{Glavan2020}. It is shown that the regularized $4D$ Einstein-Lovelock gravity theories of odd order $N > 3$ do not possess any physical isolated critical point. In fact, the critical (inflection) points of equation of state always occurs for the branch of black holes with negative entropy. The situation is quite different for the case of the regularized $4D$ Einstein-Lovelock gravity with cubic curvature corrections ($N=3$). In this case ($N=3$), although the entropy is non-negative and the equation of state of hyperbolic vacuum black holes has a nonstandard Taylor expansion about its inflection point, but there is no criticality associated with this special point. At this point, the physical properties of the black hole system change drastically, e.g., both the mass and entropy of the black hole vanishes, meaning that there do not exist degrees of freedom in order for a phase transition to occur. These results are in strong contrast to those findings in Lovelock gravity.Comment: 8 pages, 4 figures, 1 tabl

Changing QRS Morphology: What is the mechanism?

ECG in sinus rhythm with ventricular preexcitation and changing QRS morphology was seen that was initially interpreted as the multiple accessory pathway from elsewhere. (Figure 1A). The following mechanisms are potentially involved in the electrogenesis of changing QRS morphology in WPW syndrome: 1) multiple accessory pathways1; 2) simultaneous occurrence of aberrant atrioventricular conduction with accessory pathway conduction 2; 3) ventricular fusion of preexcited sinus impulse with ectopic impulse. Electrophysiologic study showed short PR (75 ms) interval with wide QRS (152 ms) and negative HV (-12 ms) interval. No change in delta wave polarity was observed during HRA and CS pacing. In full preexcitation, no breakthrough was seen in the CS. During incremental ventricular pacing, atrial breakthrough site is initially recorded on the HRA catheter and then changed to distal pole of CS catheter with progressive decrease in pacing cycle length. During ventricular pacing at cycle length of 500 ms (S1), earliest atrial activity is recorded on HRA catheter. Changing QRS could not be explained by presence of multiple APs because only right-sided AP had bidirectional conduction and no distal CS breakthrough was seen simultaneous with changing QRS morphology. The possibility of aberrant conduction is excluded by presence of negative HV interval in the beats with differing QRS morphology. No sinus cycle length variation before and after the beats with different morphologies are against the occurrence of functional LBBB. The prematurity of ventricular electrogram in His recording catheter with variable HV (H-electrogram is recorded after V-electrogram in second beat and before V-electrogram in third beat) and fixed V-RB intervals (interval from ventricular electrogram in His to the RB potential) are compatible with ventricular fusion of preexcited sinus impulse with ectopic ventricular impulse originating from parahissian area (explaining LBBB and inferior axis morphology of the beats with changing QRS) but not from the His bundle or RBB itself (because H-electrogram and RB potential is recorded after V-electrogram in the second beat with greater degree of ventricular fusion)(Figure 1B)

A Survey on using online database by faculty members and graduate students at Shahid Beheshti University

Currtent paper study on using Shahid Beheshti\u27s subscribed database by faculty members and graduate students of this University.This is a survey study with descriptive approach. The population of the study, 780 faculty members and 2,300 students graduate Shahid Beheshti University who this number using Morgan table for sampling 330 graduate students and 260 faculty members randomly stratified the samples were selected. Subscried databases Persian and Latin at the University martyr Beheshti also were examined. For data gathering the questionnaire and log files were used. Current study indicated that the indicators like amount of using and the degree of satisfaction of databases success rate by users interact with the base in this study of middle-level users, as well as faculty members and Shahid Beheshti University graduate students about the need for training in the use of shared databases positive. The most frequent users of faculty members with expertise in computer science and academic rank of associate professor and graduate students with educational science, physics and chemistry and a master\u27s degree. Current research revealed that Sciencedirect and Magiran had the most use by users

Wideband direction of arrival estimation techniques for a class of arbitrary array geometries

Array signal processing is an established field with a number of available advanced powerful technologies for detecting and locating signals that arrive at a set of sensors in the presence of noise. The focus of this thesis is on development of direction of arrival (DOA) estimation techniques for both narrowband and wideband signal sources. For narrowband signals, the multiple signal classification (MUSIC) and weighted subspace fitting (WSF) algorithms based on subspace decomposition techniques are considered. These subspace methods are subsequently extended to the more challenging and interesting wideband signals by incorporating advanced algorithms such as incoherent signal subspace method (ISM) and coherent signal subspace method (CSM). Extension of the WSF algorithm to a framework based on CSM is also investigated

White blood cell count to mean platelet volume ratio as a novel non-invasive marker predicting long-term outcomes in patients with non-ST elevation acute coronary syndrome

Background: Total white blood cell (WBC) count and mean platelet volume have previously been shown to predict outcomes in acute coronary syndrome (ACS) patients. In this prospective study, we sought to determine the prognostic value of baseline WBC count to mean platelet volume ratio (WMR) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS). Methods: A total of 490 patients with NSTE-ACS were prospectively enrolled. The relationship between baseline WMR and major adverse cardiovascular events (MACE) incidence was assessed during a mean follow-up of 330.8 ± 38 days. Results: The patients’ mean age was 60.4 ± 12.9 year, 59% of them were male. The patients were categorized into two groups based on WMR values, high- and low-WMR groups (< 755 vs. ≥ 755). The incidence of MACE was significantly higher in high-WMR compared with that of low-WMR group (22.4% vs. 10.7%, p < 0.001). Total WBC counts (median 7.9 vs. 6.9 ×103/μL, p = 0.004), neutrophil count (median 4.6 vs. 4.2 ×103/μL, p = 0.021), and WMR (median 863.2 vs. 731.5, p = 0.001) were significantly higher in the MACE-positive than MACE-negative group. The high-WMR was found to be significantly associated with the MACE-free survival rate (p < 0.001). In an adjusted cox regression model, the elevated WMR was independently predicted the incidence of MACE (hazard ratio 2.419, 95% CI 1.515–3.862, p < 0.001). Conclusions: The elevated baseline WMR independently predicted the MACE incidence in patients with NSTE-ACS during long-term follow-up.

Comparison the Students’ Ability in Answering to Patient-Management Problem and Modified Essay Question Examination with Multiple-Choice Question Examination and its Association with Educational Promotion

Background & Objective: The present study aimed to compare the students’ ability in answering to patient management problem (PMP) and modified essay question (MEQ) examination with multiple-choice question (MCQ) examination and its association with educational promotion. Methods: This research carried out in two sections descriptive-analytic and qualitative on 76 nutrition students of Kerman University of Medical Sciences, Iran, who were selected by census. The first and second examinations were PMP-MEQ and MCQ, respectively. Educational promotion variables were grade point average (GPA) in 5 sequence semesters and GPA in current semester. The other variables were the grade in food toxicology course, the scores in PMP-MEQ, PMP and MEQ exams and MCQ exam. The second section was designed with the aim of comparing the overview of students in regard to PMP-MEQ and MCQ exams. Data were analyzed by descriptive and analytic statistics. Results: The association between educational promotion variables and mark of food toxicology course and MCQ exam were statistically significant (P < 0.001); however, there was not a statistically significant association between these variables and the other variables. Mean differences scores of MCQ and food toxicology course were significant (P < 0.001); however, scores of PMP-MEQ test and PMP and MEQ sections in two students groups based on categorized GPA were not statistically significant. Conclusion: Therefore, the students’ inability in answering to PMP and MEQ examination in comparing to the MCQ examination format was showed students’ incapability in evaluation of clinical competence even with regard to their high GPA and scientific knowledge. Keywords Patient management problem (PMP) Modified essay question (MEQ) Multiple-choice question (MCQ) Educational promotion Clinical competenc