3,404 research outputs found
Assessment of Mercury Content in Louisiana\u27s Freshwater Fish and its Association to Se Concentrations
Ample evidence has demonstrated the neurotoxic properties of organic Hg to humans. However, recent studies have proposed the protective effects of Se against organic Hg detected in marine fish. Louisiana’s freshwater bodies are exploited by recreational anglers that enjoy fishing as recreational activity and food source. Thus, testing of Hg in Louisiana was resumed in 2017 to update the state advisories. However, before drawing conclusions based solely on organic Hg, it might be useful to see how much Se is present in freshwater fish. The main objective of this study was to determine the Se:Hg molar ratio in Louisiana’s freshwater fish; the ratios should be greater than 1.0 to expect Se’s protective effects. Five waterbodies were surveyed (University lake, Calcasieu lake, Toledo Bend, Atchafalaya River, and Henderson lake). The last three are listed in the state advisory. The fish’s fillet from species such as: Black drum, Catfish, Largemouth bass, Bluegill, Gizzard shad; were tested for total Hg via Direct Mercury Analyzer. Testing for Se used the same fish samples for determination via ICP-MS. The results revealed Hg concentrations on Louisiana’s fish were all under the 1 ppm EPA limit and LDEQ limit of 0.88 ppm (from 0.0063 to 0.67 ppm). However, Se concentrations were variable for different species and locations (from 0.024 to 0.886 ppm). Therefore, the calculated Se:Hg molar ratios were variable. Some ratios may suggest a relationship by species; like in Black drum and Catfish. Notwithstanding, large species (Bass) accumulate large amounts of Hg that exceed Se concentrations. That explained the low ratios for Se in Henderson lake’s bass but, is not true for Atchafalaya’s bass. Thus, fish from locations highly polluted with Hg apparently have Se:Hg molar ratios less than 1. There is no clear dominant variable (species or location) on the ratio determination. In conclusion, the predicted variability of Se in freshwater fish by other scholars were observed in this study. Apparently, location and species are variables with unpredictable dominant roles. For proper evaluation of state advisory, both might be considered independently for any particular freshwater body
Quaternions : une representation parametrique systematique de rotations finies : partie 2 : quelques applications
Projet MODULEFRésumé disponible dans le fichier PD
Revisión estado del Arte de la tecnología Bluetooth
RESUMENEste artículo presenta una revisión de estado del arte de la tecnología Bluetooth desde sus primeros planteamientos hasta el estándar hoy día, además se hace un enfoque de investigación orientado hacia el ámbito de la biomedicina y el área del cuidado de la salud en procura de identificar las mejores características de esta tecnología para futuras innovaciones de dispositivos médicos implementando bluetooth.ABSTRACTThis paper presents an overview of state of the art Bluetooth technology from its early approaches to the standard today also a forward field of biomedicine and the area of health care approach seeks to identify the research is done best features of this technology for future innovations in medical devices implementing bluetooth
Wnt/β-catenin signaling stimulates the expression and synaptic clustering of the autism-associated Neuroligin 3 gene
Indexación: Scopus.Synaptic abnormalities have been described in individuals with autism spectrum disorders (ASD). The cell-adhesion molecule Neuroligin-3 (Nlgn3) has an essential role in the function and maturation of synapses and NLGN3 ASD-associated mutations disrupt hippocampal and cortical function. Here we show that Wnt/β-catenin signaling increases Nlgn3 mRNA and protein levels in HT22 mouse hippocampal cells and primary cultures of rat hippocampal neurons. We characterized the activity of mouse and rat Nlgn3 promoter constructs containing conserved putative T-cell factor/lymphoid enhancing factor (TCF/LEF)-binding elements (TBE) and found that their activity is significantly augmented in Wnt/β-catenin cell reporter assays. Chromatin immunoprecipitation (ChIP) assays and site-directed mutagenesis experiments revealed that endogenous β-catenin binds to novel TBE consensus sequences in the Nlgn3 promoter. Moreover, activation of the signaling cascade increased Nlgn3 clustering and co-localization with the scaffold PSD-95 protein in dendritic processes of primary neurons. Our results directly link Wnt/β-catenin signaling to the transcription of the Nlgn3 gene and support a functional role for the signaling pathway in the dysregulation of excitatory/inhibitory neuronal activity, as is observed in animal models of ASD.https://www.nature.com/articles/s41398-018-0093-y.pd
El cuidado de enfermería al adulto mayor en la enfermedad vascular cerebral
A lo largo del tiempo distintos autores han esbozado diversas definiciones en relación al adulto
mayor. A continuación se presentan las siguientes definiciones:
La Organización Panamericana de Salud, considera como personas mayores a aquellas que
tienen 60 años o más; así mismo desde el punto de vista funcional se puede clasificar en tres
grupos a las personas adultas mayores. (29)
Persona adulta mayor autovalente; la persona puede realizar las actividades básicas
de su vida diaria,
Persona adulta mayor postrada; aquella que tiene una pérdida del estado de reserva
fisiológico.
Persona adulta mayor frágil; aquella persona que tiene disminución del estado de reserva fisiológic
1-Ethenyl-4-[(phenylsulfanyl)methyl]benzene
The dihedral angle between the aromatic rings in the title compound, C15H14S, is 72.38 (7)°. In the crystal, the molecules are connected by C—H⋯π interactions
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