744 research outputs found

    Finance, growth and social fairness:Evidence for Latin America and Bolivia

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    This PhD thesis explores the role of finance in promoting economic growth and social fairness. Our case studies concentrate on Latin America and the Caribbean, and on Bolivia, a developing region and a country for which the relationship between finance, growth, and social fairness turns out to be particularly important. Bolivia is considered as one of the poorest and most unequal countries in Latin America and the Caribbean. Poverty and inequality are not only deeply rooted in the country, but they are also among the most distinctive features of the region. In general, economic growth in Latin American countries has not met expectations, regardless of significant institutional reforms and an inherent potential to fare better. Consequently, the identification of factors that would promote economic growth and social fairness in Bolivia and the region becomes transcendental and necessary. At the same time, the study seeks to contribute to the scarce regional and single country-level research in this field. To pursue this goal, theoretical and empirical literature has been reviewed and original empirical evidence prepared. Moreover, the goal of this research is to conduct an integral investigation that does not rely only on macroeconomic evidence (at the regional and single country level) but also uses microeconomic evidence regarding the role of value chain financial mechanisms in a value chain case study. Throughout the thesis, different dimensions of finance such as financial depth, access to finance, and institutional diversification have been taken into account. Several of these aspects of finance have recently been studied in the empirical literature. Additionally, regarding the limited access to finance for certain agents in Bolivia – in particular, small-sized firms and rural and poor households – value chain finance has been considered as an important alternative for making financial services accessible. The results of this dissertation have implications for the design of financial and social policies for the Latin American and Caribbean region and for Bolivia

    Sustainable Supply Chain Management Drivers and Barriers in the Ethiopian Manufacturing Sec-tor

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    The prime essence of this paper is to identify the drivers of Sustainable Supply Chain Management (SSCM) and determine the barriers to its implementation in the Ethiopian manufacturing sector. Studies related to SSCM mainly from 2010 onwards are reviewed, analysed and discussed using exploratory and meta-synthesis analyses. The findings indicate that there is an absence of a clear connection between SSCM practices and performance among the manufacturing industries in Ethiopia. This creates a hindrance for manufacturing firms in Ethiopia seeking to implement SSCM

    Time delays, choice of energy-momentum variables, and relative locality in doubly special relativity

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    Doubly special relativity (DSR) theories consider (quantum-gravity motivated) deformations of the symmetries of special relativity compatible with a relativity principle. The existence of time delays for massless particles, one of their proposed phenomenological consequences, is a delicate question since, contrary to what happens with Lorentz invariance violation scenarios, they are not simply determined by the modification in the particle dispersion relation. While some studies of DSR assert the existence of photon time delays, in this paper we generalize a recently proposed model for time delay studies in DSR and show that the existence of photon time delays does not necessarily follow from a DSR scenario, determining in which cases this is so. Moreover, we clarify long-standing questions about the arbitrariness in the choice of the energy-momentum labels and the independence of the time delay on this choice, as well as on the consistency of its calculation with the relative locality paradigm of DSR theories. Finally, we show that the result for time delays is reproduced in models that consider propagation in a noncommutative spacetime

    Wnt/β-catenin signaling stimulates the expression and synaptic clustering of the autism-associated Neuroligin 3 gene

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    Indexación: Scopus.Synaptic abnormalities have been described in individuals with autism spectrum disorders (ASD). The cell-adhesion molecule Neuroligin-3 (Nlgn3) has an essential role in the function and maturation of synapses and NLGN3 ASD-associated mutations disrupt hippocampal and cortical function. Here we show that Wnt/β-catenin signaling increases Nlgn3 mRNA and protein levels in HT22 mouse hippocampal cells and primary cultures of rat hippocampal neurons. We characterized the activity of mouse and rat Nlgn3 promoter constructs containing conserved putative T-cell factor/lymphoid enhancing factor (TCF/LEF)-binding elements (TBE) and found that their activity is significantly augmented in Wnt/β-catenin cell reporter assays. Chromatin immunoprecipitation (ChIP) assays and site-directed mutagenesis experiments revealed that endogenous β-catenin binds to novel TBE consensus sequences in the Nlgn3 promoter. Moreover, activation of the signaling cascade increased Nlgn3 clustering and co-localization with the scaffold PSD-95 protein in dendritic processes of primary neurons. Our results directly link Wnt/β-catenin signaling to the transcription of the Nlgn3 gene and support a functional role for the signaling pathway in the dysregulation of excitatory/inhibitory neuronal activity, as is observed in animal models of ASD.https://www.nature.com/articles/s41398-018-0093-y.pd

    Modification of the mean free path of very high-energy photons due to a relativistic deformed kinematics

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    Ultra-high-energy physics is about to enter a new era thanks to the impressive results of experiments such as the Large High Altitude Air Shower Observatory, detecting photons of up to 1.4×10^15 eV (PeV scale). These new results could be used to test deviations with respect to special relativity. While this has been already explored within the approach of Lorentz Invariance Violation theories, in this work we consider, for the first time, modifications due to a relativistic deformed kinematics (which appear in Doubly Special Relativity, or DSR, theories). In particular, we study the mean free path of very high-energy photons due to electron-positron pair creation when interacting with low-energy photons of the cosmic microwave background. Depending on the energy scale of the relativistic deformed kinematics, present (or near future) experiments can be sensitive enough to be able to identify deviations from special relativity

    Physics of the universe transparency in a deformed kinematics

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    We present a first study of the possible effects of a relativistic deformation of special relativity in the recent observations of very high-energy gamma rays by the LHAASO experiment, which has opened a new phenomenological window to study deformations in the kinematics of special relativity. Our analysis of the interaction of high-energy photons with the CMB background complements theoretical studies based on Lorentz invariance violation scenarios, while making predictions that would allow one to distinguish between a violation and a deformation of the symmetries of special relativity

    PHP8 Measuring Adherence to Drug Treatment in Mexican Patients: A Systematic Review

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    Estilo de vida y estado de nutrición en niños escolares

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    ResumenObjetivoRelacionar el estilo de vida y el estado de nutrición en escolares.MétodoEstudio correlacional, participaron 260 niños adscritos a la Clínica ISSSTE, elegidos aleatoriamente. Se utilizó el cuestionario sobre estilos de vida en la niñez y se valoró el peso y talla. Se obtuvo la aprobación de la Jefatura de Investigación del ISSSTE. En el análisis de datos se aplicó estadística descriptiva e inferencial.ResultadosParticiparon 137 niños y 123 niñas, con edades entre 6-12 años. Respecto al estado de nutrición, 5 de cada 10 de los participantes se encuentran en peso normal, 2 de cada 10 en sobrepeso y uno de cada 10 en obesidad y peso bajo. Sobre el estilo de vida 7 de cada 10 de los participantes se encontraron en riesgo bajo y 2 de cada 10 en riesgo mediano. Por otra parte, no se encontró relación entre el estilo de vida de los niños y su estado de nutrición (rs=0.038, p>0.05). Adicionalmente, se encontró que los niños con peso normal o bajo peso tienen mejores hábitos de sueño que los niños con sobrepeso u obesidad (U=3.79, p<0.001).ConclusionesEste estudio muestra indicios de que los aspectos vinculados con la dimensión psicocorporal y con uso del tiempo libre deberían indagarse a mayor profundidad, ya que fueron los que arrojaron cifras que ubican a los escolares en riesgo medio y alto.AbstractObjectiveTo explore the association between lifestyle and nutritional status among school children.MethodCorrelational study involving 260 children registered at an ISSSTE clinic, who were randomly selected. A questionnaire on childhood lifestyles was used; weight and height were also assessed. A project approval from the ISSSTE research committee was obtained. Descriptive and inferential statistics were used.Results137 boys and 123 girls with ages between 6 and 12 years old participated. In relation to the nutrition status, five out every ten have a normal weight; two out every ten are over weighted, and one out of every ten is obese or under weighted respectively. In relation to lifestyle, seven out of every ten participants have low risk; and two out of every ten have medium risk. On the other hand a relation between the lifestyle and nutritional status of the children was not found (rs=.038, p>0.05). Moreover, it was found that children with normal or low weights have better sleep habits in comparison to the children who are over weighted or obese U=3.79, p <.001).ConclusionsThis study suggests that issues related to the psychological and corporal dimensions, as well as the use of free time, should be further explored because they showed figures which place children within mid and high risks
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