Recurrence rates after EMR of large sessile serrated polyps

Background Little is known regarding the recurrence rate after EMR of large (≥20 mm) sessile serrated adenoma/polyps (SSA/Ps). Objective To compare the recurrence rate among SSA/Ps and conventional adenomas in patients referred to a specialty practice for EMR. Design Retrospective cohort study. Setting Academic hospital and a satellite surgery center. Patients A total of 362 consecutive patients referred for resection of large (≥20 mm) polyps in the colorectum. Interventions All EMRs were performed with a submucosal contrast agent. All subjects had a follow-up surveillance examination (inspection and biopsy of the EMR) at our center. Main Outcome Measurements Rates of residual polyp at follow-up examination. Results Residual polyp was identified among 8.7% of SSA/Ps compared with 11.1% for conventional adenomas (P = .8). Limitations Retrospective design, procedures performed by a single experienced endoscopist, low number of serrated lesions. Conclusions The rate of recurrence after EMR of SSA/Ps is similar to the rate after EMR of conventional adenomas

The far-infrared/submillimeter properties of galaxies located behind the Bullet cluster

The Herschel Lensing Survey (HLS) takes advantage of gravitational lensing by massive galaxy clusters to sample a population of high-redshift galaxies which are too faint to be detected above the confusion limit of current far-infrared/submillimeter telescopes. Measurements from 100–500 μm bracket the peaks of the far-infrared spectral energy distributions of these galaxies, characterizing their infrared luminosities and star formation rates. We introduce initial results from our science demonstration phase observations, directed toward the Bullet cluster (1E0657-56). By combining our observations with LABOCA 870 μm and AzTEC 1.1 mm data we fully constrain the spectral energy distributions of 19 MIPS 24 μm-selected galaxies which are located behind the cluster. We find that their colors are best fit using templates based on local galaxies with systematically lower infrared luminosities. This suggests that our sources are not like local ultra-luminous infrared galaxies in which vigorous star formation is contained in a compact highly dust-obscured region. Instead, they appear to be scaled up versions of lower luminosity local galaxies with star formation occurring on larger physical scales

We Have Some Soft Corn

Many Iowa farms have a lot of soft corn, and most farms have corn with high moisture content to be taken care of this fall. The wet spring and the necessity of replanting many fields made this unavoidable. The problem now is how best to handle it

The predictive value of small versus diminutive adenomas for subsequent advanced neoplasia

Background and Aims Patients with previous colorectal adenomas are at increased risk of colorectal cancer. Current guidelines for postpolypectomy surveillance intervals treat all tubular adenomas 1 to 9 mm in size with low-grade dysplasia as carrying the same level of risk. We evaluated whether 6 to 9 mm adenomas detected at colonoscopy are associated with greater risk of advanced neoplasia at follow-up compared with baseline 1 to 5 mm adenomas. Methods We retrospectively evaluated a colonoscopy database at a single U.S. academic center. Patients with baseline examinations demonstrating tubular adenomas 1 to 9 mm in size with low-grade dysplasia and no advanced adenomas were included. Follow-up colonoscopies were performed at least 200 days later and were assessed for incident advanced neoplasia (cancer, high-grade dysplasia, adenoma ≥10 mm in size, or villous elements). Results There were 2477 qualifying baseline colonoscopies. The absolute risk of metachronous advanced neoplasia increased from 3.6% in patients with 1 to 5 mm adenomas to 6.9% in patients with at least 1 adenoma of 6 to 9 mm (P = .001). Patients with 5 or more adenomas 1 of which was at least 6 to 9 mm had the highest risk of advanced neoplasia at follow-up (10.4%, P = .006). When only screening colonoscopies were considered, all baseline groups (1-2 adenomas, 3-4 adenomas, ≥5 adenomas) with adenomas 6 to 9 mm in size had an increased risk for metachronous advanced neoplasia (odds ratio [OR], 4.07; 95% confidence interval [CI], 1.50-11.04; OR, 4.91; 95% CI, 1.44-16.75; OR, 4.71; 95% CI, 1.30-17.05, respectively). Conclusions Patients with baseline small (6-9 mm) adenomas have an increased risk of advanced lesions on follow-up compared with patients with only diminutive (1-5 mm) adenomas. Postpolypectomy guidelines should consider risk stratification based on small versus diminutive adenomas

Laboratory measurements of polar stratospheric cloud rate parameters

It is now clear that heterogeneous reactions play an important role in controlling the concentration of ozone in the stratosphere. In this work, the loss of N2O5 on ice substrates has been studied in a flow reactor in an attempt to gain a more fundamental understanding of these reactions. The apparent reaction probability in this system was found to decrease as the substrate was exposed to N2O5. A model which corrected for the loss of surface sites was developed and although it appears to fit the data for a given experiment quite well, it is concluded that the loss of reactive sites is not the full explanation. In addition, the results of an experimental and modeling study suggest that reaction on the internal surface of the ice substrates is not a major loss mechanism for N2O5 in the current work

Fresnel filtering in lasing emission from scarred modes of wave-chaotic optical resonators

We study lasing emission from asymmetric resonant cavity (ARC) GaN micro-lasers. By comparing far-field intensity patterns with images of the micro-laser we find that the lasing modes are concentrated on three-bounce unstable periodic ray orbits, i.e. the modes are scarred. The high-intensity emission directions of these scarred modes are completely different from those predicted by applying Snell's law to the ray orbit. This effect is due to the process of ``Fresnel filtering'' which occurs when a beam of finite angular spread is incident at the critical angle for total internal reflection.Comment: 4 pages, 3 figures (eps), RevTeX 3.1, submitted to Phys. Rev. Lett; corrected a minor (transcription) erro

Coupled KdV equations derived from atmospherical dynamics

Some types of coupled Korteweg de-Vries (KdV) equations are derived from an atmospheric dynamical system. In the derivation procedure, an unreasonable $y$-average trick (which is usually adopted in literature) is removed. The derived models are classified via Painlev\'e test. Three types of $\tau$-function solutions and multiple soliton solutions of the models are explicitly given by means of the exact solutions of the usual KdV equation. It is also interesting that for a non-Painlev\'e integrable coupled KdV system there may be multiple soliton solutions.Comment: 19 pages, 2 figure

A revision of the British Chronostratigraphy within the Last Glacial-Interglacial Cycle based on new evidence from Arclid, Cheshire UK

Of the 24 Greenland interstadials (GI) in the Last Glacial-interglacial cycle (LGIC) only five are conventionally recognised in Britain. This paper aims to improve understanding of the LGIC in Britain from a site at Arclid, Cheshire. Sediments were characterised and luminescence used to establish a chronology. This found that the Chelford Sand Formation spans 77-47 ka with sand deposited initially by aeolian but later by fluvial transportation. Coleoptera and Diptera from the basal peat lens provided a reconstruction for a heather-rich heathland environment grazed by large herbivores, with summer temperatures between 13-18° C, and winter temperatures between -14 and 1°C. Flies included the earliest records of the blood-sucking horsefly Haematopota pluvialis, and the soldierfly Chloromyia formosa. The overlying Stockport Sand Formation was deposited fluvioglacially between 47-41 ka with the upper Stockport Till formed by the advance of the last British icesheet after ~33 ka. Stenothermic beetle analysis from Arclid indicate similarities with results from other British mid LGIC sites, some of which are at or beyond the limit of radiocarbon dating and may be of a similar age to Arclid. Basal organic sediments found at Arclid along with other reassigned sites are proposed as a new Arclid Interstadial. A revised British LGIC chronostratigraphy has the Wretton, Chelford and Brimpton Interstadials and the previously suggested but not widely recognised Cassington Interstadial. The Arclid Interstadial occurred after these, but prior to the Upton Warren Interstadial complex. This closes the previous gap in interstadials between the Brimpton Interstadial and the Upton Warren Interstadial complex within the British chronostratigraphy

Chaos, containment and change: responding to persistent offending by young people

This article reviews policy developments in Scotland concerning 'persistent young offenders' and then describes the design of a study intended to assist a local planning group in developing its response. The key findings of a review of casefiles of young people involved in persistent offending are reported. It emerges that youth crime and young people involved in offending are more complex and heterogeneous than is sometimes assumed. This, along with a review of some literature about desistance from offending, reaffirms the need for properly individualised interventions. Studies of 'desisters' suggest the centrality of effective and engaging working relationships in this process. However, these studies also re-assert the significance of the social contexts of workers’ efforts to bring 'change' out of 'chaos'. We conclude therefore that the 'new correctionalism' must be tempered with appreciation of the social exclusion of young people who offend

SANEPIC: A Map-Making Method for Timestream Data From Large Arrays

We describe a map-making method which we have developed for the Balloon-borne Large Aperture Submillimeter Telescope (BLAST) experiment, but which should have general application to data from other submillimeter arrays. Our method uses a Maximum Likelihood based approach, with several approximations, which allows images to be constructed using large amounts of data with fairly modest computer memory and processing requirements. This new approach, Signal And Noise Estimation Procedure Including Correlations (SANEPIC), builds upon several previous methods, but focuses specifically on the regime where there is a large number of detectors sampling the same map of the sky, and explicitly allowing for the the possibility of strong correlations between the detector timestreams. We provide real and simulated examples of how well this method performs compared with more simplistic map-makers based on filtering. We discuss two separate implementations of SANEPIC: a brute-force approach, in which the inverse pixel-pixel covariance matrix is computed; and an iterative approach, which is much more efficient for large maps. SANEPIC has been successfully used to produce maps using data from the 2005 BLAST flight.Comment: 27 Pages, 15 figures; Submitted to the Astrophysical Journal; related results available at http://blastexperiment.info/ [the BLAST Webpage