Structural identification and presence of some p-menth-1-enediols in grape products

The present work aims at clearing the structure of some p-menthenediols, which are already known to be present in musts and wines as glycosides, referred to as isomers 1, 2 and 3. Isomers 2 and 3 correspond to cis-p-menth-1-ene-6,8-diol and p-menth-1-ene-7,8-diol; isomer 1, which is only found in traces, is probably identical with trans- p-menth-1-ene-6,8-diol. Their concentration is reported for both free and bound forms in musts from some varieties and compared with the alpha-terpineol and 2-exo-hydroxy-1,8-cineole concentrations. In general, the free forms were scarcely present; among the bound forms p-menth-1-ene-7,8-diol first and then cis-p-menth-1-ene-6,8-diol prevailed. Besides improvement of varietal classification, the compounds identified give evidence of allylic hydroxylase activity in grape berries

Identification of two stilbenoids from Vitis roots

Two oligostilbenes were isolated from roots of Vitis vinifera cv. Chardonnay and their structures were identified. One compound, ampelopsin A, is a dimer of resveratrol and has been found previously only in the roots of Ampelopsis brevipedunculata var. hancei (Vitaceae). The second, hopeaphenol, can be regarded as a dimer of ampelopsin A; its presence in Vitaceae is reported here for the first time. Both compounds are present in mg per g levels in vine roots

Prenatal exposures and exposomics of asthma

This review examines the causal investigation of preclinical development of childhood asthma using exposomic tools. We examine the current state of knowledge regarding early-life exposure to non-biogenic indoor air pollution and the developmental modulation of the immune system. We examine how metabolomics technologies could aid not only in the biomarker identification of a particular asthma phenotype, but also the mechanisms underlying the immunopathologic process. Within such a framework, we propose alternate components of exposomic investigation of asthma in which, the exposome represents a reiterative investigative process of targeted biomarker identification, validation through computational systems biology and physical sampling of environmental medi

Carbon Stable Isotops and Olive Oil Adulteration. Note II.

This research has evidenced that the delta13C values for aliphatic aloholic fraction of pomace olive oils isolated after UE method were significantly more negative than those of virgin and refined olive oils. These findings were explained by the presence in pomace olive oil and virgin or refined olive oils of very different quantities of isoprenoids and methylsterols.JRC.(EI)-Environment Institut