1,464 research outputs found
Revisión de estrategias para reconstrucción de la corriente de entrada
Understanding the theory of active power factor correction in single-phase regulators can be quite complex for young students. This is even more critical if one considers the diversity of strategies that exist, their combinations, and even the existence of both passive and active strategies. In some way, all these approaches seek to reconstruct the input current signal, but the strategy used may be significantly different in each case. This article aims to present an overview of these techniques that can be used as a starting point for the study and design of equipment.Entender la teoría de la corrección activa del factor de potencia en reguladores monofásicos puede ser bastante complejo para jóvenes estudiantes. Esto es aún más critico si se considera la diversidad de estrategias que existen, sus combinaciones, e incluso la existencia de estrategias tanto pasivas como activas. De alguna forma todas estas estrategias buscan reconstruir la señal de corriente de entrada, pero la estrategia utilizada puede ser sensiblemente diferente en cada caso. En este artículo se busca presentar una visión general de estas estrategias que sirva de punto de partida tanto para estudio como para el diseño de equipos
Comparison of Potential Sites in China for Erecting a Hybrid Solar Tower Power Plant with Air Receiver
AbstractIn this work transient simulation results of a hybrid solar tower power plant with openvolumetric receiver technology are presented for several locations in China. The openvolumetric receiver uses ambient air as heat transfer fluid and the hybridization can be realized with additional firing. The solar receiver and/or the additional firing heat up the air which is then passed through a boiler of a conventional Rankine cycle. The simulated plantis based on the configuration of the solar thermal test and demonstration power plant located in Jülich (STJ). The investigatedplant operates in hybrid - parallelmode which allows a constant power generation. The meteorological data for the different sites in China was taken from the software Meteonorm in a time resolution of one hour. The solar tower power simulation tool was developed in the simulation environment MATLAB/Simulink
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The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
The long term side effects of any newly introduced drug is a subject of intense research, and often raging controversies. One such example is the dipeptidyl peptidase-IV (DPP4) inhibitor used for treating type 2 diabetes, which is inconclusively implicated in increased susceptibility to acute pancreatitis. Previously, based on a computational analysis of the spatial and electrostatic properties of active site residues, we have demonstrated that phosphoinositide-specific phospholipase C (PI-PLC) from Bacillus cereus is a prolyl peptidase using in vivo experiments. In the current work, we first report the inhibition of the native activity of PI-PLC by two DPP4 inhibitors - vildagliptin (LAF-237) and K-579. While vildagliptin inhibited PI-PLC at micromolar concentrations, K-579 was a potent inhibitor even at nanomolar concentrations. Subsequently, we queried a comprehensive, non-redundant set of 5000 human proteins (50% similarity cutoff) with known structures using serine protease (SPASE) motifs derived from trypsin and DPP4. A pancreatic lipase and a gastric lipase are among the proteins that are identified as proteins having promiscuous SPASE scaffolds that could interact with DPP4 inhibitors. The presence of such scaffolds in human lipases is expected since they share the same catalytic mechanism with PI-PLC. However our methodology also detects other proteins, often with a completely different enzymatic mechanism, that have significantly congruent domains with the SPASE motifs. The reported elevated levels of serum lipase, although contested, could be rationalized by inhibition of lipases reported here. In an effort to further our understanding of the spatial and electrostatic basis of DPP4 inhibitors, we have also done a comprehensive analysis of all 76 known DPP4 structures liganded to inhibitors till date. Also, the methodology presented here can be easily adopted for other drugs, and provide the first line of filtering in the identification of pathways that might be inadvertently affected due to promiscuous scaffolds in proteins
Equilibration of Concentrated Hard Sphere Fluids
We report a systematic molecular dynamics study of the isochoric
equilibration of hard-sphere fluids in their metastable regime close to the
glass transition. The thermalization process starts with the system prepared in
a non-equilibrium state with the desired final volume fraction {\phi} but with
a prescribed non-equilibrium static structure factor S_0(k; {\phi}). The
evolution of the {\alpha}- relaxation time {\tau}{\alpha} (k) and long-time
self-diffusion coefficient DL as a function of the evolution time tw is then
monitored for an array of volume fractions. For a given waiting time the plot
of {\tau}{\alpha} (k; {\phi}, tw) as a function of {\phi} exhibits two regimes
corresponding to samples that have fully equilibrated within this waiting time
({\phi} \leq {\phi}(c) (tw)), and to samples for which equilibration is not yet
complete ({\phi} \geq {\phi}(c) (tw)). The crossover volume fraction {\phi}(c)
(tw) increases with tw but seems to saturate to a value {\phi}(a) \equiv
{\phi}(c) (tw \rightarrow \infty) \approx 0.582. We also find that the waiting
time t^(eq)_w({\phi}) required to equilibrate a system grows faster than the
corresponding equilibrium relaxation time, t^(eq)({\phi}) \approx 0.27 \times
[{\tau}{\alpha} (k; {\phi})]^1.43, and that both characteristic times increase
strongly as {\phi} approaches {\phi}^(a), thus suggesting that the measurement
of equilibrium properties at and above {\phi}(a) is experimentally impossible
La educación en ciencias de la naturaleza en la secundaria vista por universitarios colombianos
Se presentan los resultados de unainvestigación relacionada con la percepción del estudiantado universitario acerca de la contribución de la Educación en Ciencias de la Naturaleza recibida durante la secundariaa la formación en las competencias científicas planteadas por el Ministerio deEducación Nacional de Colombia.Los resultados muestran que un mayor número de estudiantes considera que la educación en ciencias contribuyó al desarrollo de las diversas competencias analizadas. Los factores que más influyeron en esta formación fueron la motivación propia del estudiante, las estrategias de enseñanza y las características de personalidad de los profesores. Para aquellos estudiantes que consideraron que la educación en ciencias no contribuyó a su formación, los resultados muestran que los factores que más influyeron en sus respuestas fueron las estrategias de enseñanza de los profesores, la motivación propia del estudiante y los contenidos temáticos tratados en los cursos de ciencias
Manifestation of the Roughness-Square-Gradient Scattering in Surface-Corrugated Waveguides
We study a new mechanism of wave/electron scattering in multi-mode
surface-corrugated waveguides/wires. This mechanism is due to specific
square-gradient terms in an effective Hamiltonian describing the surface
scattering, that were neglected in all previous studies. With a careful
analysis of the role of roughness slopes in a surface profile, we show that
these terms strongly contribute to the expression for the inverse attenuation
length (mean free path), provided the correlation length of corrugations is
relatively small. The analytical results are illustrated by numerical data.Comment: 13 pages, 3 figure
Gradient and Amplitude Scattering in Surface-Corrugated Waveguides
We investigate the interplay between amplitude and square-gradient scattering
from the rough surfaces in multi-mode waveguides (conducting quantum wires).
The main result is that for any (even small in height) roughness the
square-gradient terms in the expression for the wave scattering length
(electron mean free path) are dominant, provided the correlation length of the
surface disorder is small enough. This important effect is missed in existing
studies of the surface scattering.Comment: 4 pages, one figur
Anderson localization in a periodic photonic lattice with a disordered boundary
We investigate experimentally the light evolution inside a two-dimensional
finite periodic array of weakly- coupled optical waveguides with a disordered
boundary. For a completely localized initial condition away from the surface,
we find that the disordered boundary induces an asymptotic localization in the
bulk, centered around the initial position of the input beam.Comment: 3 pages, 4 figure
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