15 research outputs found
Associação entre concentrações séricas de minerais, índices antropométricos e ocorrência de diarréia entre crianças de baixa renda da região metropolitana do Rio de Janeiro
- Author
- Ana Paula Black Veiga
- Anjos MJ
- Baqui AH
- Baqui AH
- Batista Filho M
- Bhan MJ
- Bhandari N
- Black R
- Brutta ZA
- Costa RSS
- Costa-Neto C
- Cássia Viviane Dantas Borges
- Edgar Francisco Oliveira de Jesus
- Ernan P
- Fernandes BS
- Fisberg M
- Gabriela dos Santos Barroso
- Hautvast JL
- Hernández-Carabalho EA
- Krause M
- Mahalanabis D
- Milne DB
- Monte CMG
- Monteiro CA
- Nakamura NH
- Patel AB
- Penny ME
- Renata Faria Barbosa Serpa
- Roche AF
- Rosana Salles-Costa
- Salgueiro MJ
- Shils ME
- Silvana Moreira
- Singh M
- Stephensen CB
- Umesh KMD
- Villalpando S
- Walter CF
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Qualidade de vida pós-unidades de terapia intensiva: protocolo de estudo de coorte multicêntrico para avaliação de desfechos em longo prazo em sobreviventes de internação em unidades de terapia intensiva brasileiras
- Author
- Alexandre Amaral
- Alexandre Biasi Cavalcanti
- Ana Paula Menezes Silveira
- André Sant'Ana Machado
- Camila Dietrich
- Caroline Cabral Robinson
- Cassiano Teixeira
- Cesar Alencar
- Cinthia Mucci Ribeiro
- Daniel Schneider
- Daniel Sganzerla
- Daniela Cunha de Oliveira
- Daniella Cunha Birriel
- Denise de Souza
- Fernanda Caleffe Moreira
- Fernando Bozza
- Francine Hoffmann Dutra
- José Mario Meira Teles
- Juliana Mara Stormosvski de Andrade
- Juliana Rezende Cardoso
- Juçara Gasparetto Maccari
- Luciana Yumi Ue
- Luciane Nascimento Cruz
- Luciano Serpa Hammes
- Lucieda Araújo Martins
- Luisa Barbosa Anzolin
- Lívia Correa e Castro
- Lúcio Couto de Oliveira Júnior
- Maicon Falavigna
- Maicon Quadro de Oliveira
- Mariana Nunes Gamboa
- Marli Sarmento da Silva
- Michelle Carneiro Teixeira
- Paula Pinheiro Berto
- Rafael Trevizoli Neves
- Regis Goulart Rosa
- Renata de Andrade Gomes
- Renata Kochhann
- Rodrigo Boldo
- Rodrigo Jeffman
- Roselaine Pinheiro de Oliveira
- Rui Leandro da Silva Santos
- Silvia Regina Rios Vieira
- Suelen Fardim de Menezes
- Sâmia Faria da Silva
- Tarek Sharshar
- Évelin Carneiro Sanchez
- Publication venue
- 'GN1 Genesis Network'
- Publication date
- 01/01/2018
- Field of study
RESUMO Objetivo: Avaliar a prevalência de incapacidades físicas, cognitivas e psiquiátricas, fatores associados e sua relação com qualidade de vida em pacientes sobreviventes de internação em unidades de terapia intensiva brasileiras. Métodos: Um estudo de coorte prospectivo multicêntrico está sendo conduzido em dez unidades de terapia intensiva adulto clínico-cirúrgicas representativas das cinco regiões geopolíticas do Brasil. Pacientes com idade ≥ 18 anos que receberam alta das unidades de terapia intensiva participantes e permaneceram internados na unidade de terapia intensiva por 72 horas ou mais, nos casos de internação clínica ou cirúrgica de urgência, e por 120 horas ou mais, nos casos de internação cirúrgica eletiva, serão incluídos de forma consecutiva. Estes pacientes serão seguidos por 1 ano, por meio de entrevistas telefônicas estruturadas 3, 6 e 12 meses pós-alta da unidade de terapia intensiva. Dependência funcional, disfunção cognitiva, sintomas de ansiedade e depressão, sintomas de estresse pós-traumático, qualidade de vida relacionada à saúde, re-hospitalizações e mortalidade em longo prazo serão avaliados como desfechos. Discussão: O presente estudo tem o potencial de contribuir para o conhecimento a respeito da prevalência e dos fatores associados à síndrome pós-cuidados intensivos na população de pacientes adultos sobreviventes de internação em unidades de terapia intensiva brasileiras. Ademais, a associação entre síndrome pós-cuidados intensivos e qualidade de vida relacionada à saúde poderá ser estabelecida
ATLANTIC BIRD TRAITS: a data set of bird morphological traits from the Atlantic forests of South America
- Author
- Alegre Vanesa Bejarano
- Alexandrino Eduardo Roberto
- Almeida Ferreira João Ricardo de
- Althmann Giulyana
- Althoff Sérgio L.
- Alves M. A.S.
- Alves-Eigenheer Milene
- Amaral Andreza Clarinda Araújo do
- Andrade Paulo Guilherme Bisetto de
- Aquino Ana Carla Medeiros Morato de
- Arantes Murilo Sérgio
- Araujo Andréa Cardoso de
- Araujo Helder Farias Pereira de
- Araújo-Lima Vitor
- Assis Julia Camara de
- Banks-Leite Cristina
- Baptista Michelle Noronha da Matta
- Barcik Jean Júnior
- Bettio Maurício
- Bispo Arthur Ângelo
- Bobato Rafaela
- Bochio Gabriela Menezes
- Bonetti Giselle Evelise
- Bosenbecker Camila
- Bovo Alex A.A.
- Braga Talita Vieira
- Bugoni Leandro
- Calsavara Larissa Corsini
- Camargo Barbosa Karlla Vanessa de
- Camargo Guaraldo André de
- Camargo Bruna Betagni de
- Carrano Eduardo
- Carvalho Maria Amélia Santos de
- Cavarzere Vagner
- Cerboncini Ricardo Augusto Serpa
- Cestari César
- Cezila Beatriz Azevedo
- Chaves Flávia Guimarães
- Costa Leonardo Marques
- Costa Thiago Vernaschi Vieira da
- Crestani Ana Cristina Vara
- Câmara Thanyria Pollyneide França
- Cândia-Gallardo Carlos Ernesto
- de Castro Pena João Carlos
- Deconto Leonardo Rafael
- Dias Rafael Antunes
- Donatelli Reginaldo José
- Doná Eder Afonso
- Duca Charles
- Efe Márcio Amorim
- Enedino Thayz Rodrigues
- Espínola Cid Rodrigo Rodriguez
- Falcon José Eduardo Teixeira
- Faria Deborah Maria
- Faria Fernando Azevedo
- Faria Rogério Rodrigues
- Farias Fernando Bittencourt de
- Faxina Claudenice
- Ferraz Kátia Maria Paschoaletto Micchi de Barros
- Ferreira Ariane
- Ferreira Carolina Demetrio
- Fischer Erich
- Fonseca Renata Cristina Batista
- Fontana Carla Suertegaray
- Francisco Mercival Roberto
- Freitas Fernando José Ferneda
- Galetti Mauro
- Gaspar Lucas P.
- Gatto Cassiano Augusto Ferreira Rodrigues
- Giese Felipe Borba
- Girardi Fabiane
- Gonçalves Fernando
- Gonçalves Mariana Lopes
- Gusmão Reginaldo Farias de
- Hasui Érica
- Jacoboski Lucilene Inês
- Jahn Alex E.
- Jesus Shayana de
- Junior Pedro Manoel Galetti
- Just João Paulo Gava
- Kanda Claudia Zukeran
- Kohler Glauco
- Lacerda Raquel Caroline Alves
- Laps Rudi Ricardo
- Las-Casas Flor Maria Guedes
- Lau Ricardo
- Leandro-Silva Victor
- Lima Favaro Fernando de
- Lima M. R.
- Lopes Leonardo Esteves
- Lugarini Camile
- Luz Daniela Tomasio Apolinario da
- Lyra Ricardo Brioschi
- Macario Phoeve
- Macarrão Arthur
- Machado Caio Graco
- Manica Lilian Tonelli
- Mariz Daniele
- Marques-Santos Fernando
- Martello Felipe
- Martins-Silva Jimi
- Mathias Leonardo B.
- Medolago César Augusto Bronzato
- Melo Marcos Antônio
- Menezes Gregório dos Reis
- Menezes Ícaro
- Metzger Jean Paul
- Meurer Rafael
- Meyer Douglas
- Meyer Marcela Afonso P.
- Missagia Caio C.C.
- Molin Tamara
- Monteiro Erison C.S.
- Morante-Filho José Carlos
- Moreno Daniele Janina
- Muylaert Renata L.
- Naka Luciano Nicol?s
- Namba Sumiko
- Neto Paulo Affonso Fonseca Pires
- Nunes Cristiane Estrêla Campodonio
- Nunes Maria Flavia Conti
- Ogrzewalska Maria Halina
- Oliveira Fratoni Rafael de
- Oliveira Lunardi Vitor de
- Oliveira Vanessa Cristina de
- Oshima Júlia Emi Faria
- Paes-Macarrão Natalia Dantas
- Paolino Roberta Montanheiro
- Persegona Jaqueline Evelyn
- Petronetto Adeliane Peterle
- Pichorim Mauro
- Piratelli Augusto J.
- Pizo Marco Aurélio
- Plucenio Gustavo Piletti
- Prates Cristine
- Provinciato Ivan Celso Carvalho
- Rajão Henrique
- Regolin André Luis
- Repenning Márcio
- Ribeiro Bianca Costa
- Ribeiro Milton Cezar
- Ribeiro Pedro Henrique Lima
- Rodrigues Licléia da Cruz
- Rodrigues Marcos
- Rodrigues Roberta Costa
- Rodrigues Rodolpho Credo
- Romagna Rafael Spilere
- Roos Andrei L.
- Roper James J.
- Rosa Gabriel Lima Medina
- Rosoni Jonas Rafael Rodrigues
- Ruiz Nicolás Luciano
- Saint-Clair Rafael S.
- Santos Andressa Hartuiq dos
- Schaedler Laura Maria
- Serafini Patrícia Pereira
- Shibuya Felipe L.S.
- Silva Elsimar Silveira da
- Silva José Nilton da
- Silveira Luis Fabio
- Silveira Natalia Stefanini da
- Souza Elivan Arantes de
- Souza-Correia Jozélia Maria de
- Tarso Zuquim de Antas Paulo de
- Tavares-Damasceno João Paulo
- Toledo-Lima Guilherme Santos
- Tonetti Vinicius R.
- Torre Gabriel Massaccesi de La
- Torres Ingrid Maria Denóbile
- Uezu Alexandre
- Vallejos Marcelo Alejandro Villegas
- Vasconcelos Marcelo Ferreira de
- Vecchi Maurício Brandão
- Viana Anderson Durão
- Viana Ivan Réus
- Vieira-Filho Arnaldo Honorato
- Willrich Guilherme
- Wischhoff Uschi
- Zocche Jairo José
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2019
- Field of study
Scientists have long been trying to understand why the Neotropical region holds the highest diversity of birds on Earth. Recently, there has been increased interest in morphological variation between and within species, and in how climate, topography, and anthropogenic pressures may explain and affect phenotypic variation. Because morphological data are not always available for many species at the local or regional scale, we are limited in our understanding of intra- and interspecies spatial morphological variation. Here, we present the ATLANTIC BIRD TRAITS, a data set that includes measurements of up to 44 morphological traits in 67,197 bird records from 2,790 populations distributed throughout the Atlantic forests of South America. This data set comprises information, compiled over two centuries (1820–2018), for 711 bird species, which represent 80% of all known bird diversity in the Atlantic Forest. Among the most commonly reported traits are sex (n = 65,717), age (n = 63,852), body mass (n = 58,768), flight molt presence (n = 44,941), molt presence (n = 44,847), body molt presence (n = 44,606), tail length (n = 43,005), reproductive stage (n = 42,588), bill length (n = 37,409), body length (n = 28,394), right wing length (n = 21,950), tarsus length (n = 20,342), and wing length (n = 18,071). The most frequently recorded species are Chiroxiphia caudata (n = 1,837), Turdus albicollis (n = 1,658), Trichothraupis melanops (n = 1,468), Turdus leucomelas (n = 1,436), and Basileuterus culicivorus (n = 1,384). The species recorded in the greatest number of sampling localities are Basileuterus culicivorus (n = 243), Trichothraupis melanops (n = 242), Chiroxiphia caudata (n = 210), Platyrinchus mystaceus (n = 208), and Turdus rufiventris (n = 191). ATLANTIC BIRD TRAITS (ABT) is the most comprehensive data set on measurements of bird morphological traits found in a biodiversity hotspot; it provides data for basic and applied research at multiple scales, from individual to community, and from the local to the macroecological perspectives. No copyright or proprietary restrictions are associated with the use of this data set. Please cite this data paper when the data are used in publications or teaching and educational activities. © 2019 The Authors. Ecology © 2019 The Ecological Society of Americ
ATLANTIC BIRD TRAITS
- Author
- Alegre Vanesa Bejarano
- Alexandrino Eduardo Roberto
- Almeida Ferreira João Ricardo de
- Althmann Giulyana
- Althoff Sérgio L.
- Alves M. A.S.
- Alves-Eigenheer Milene
- Amaral Andreza Clarinda Araújo do
- Andrade Paulo Guilherme Bisetto de
- Aquino Ana Carla Medeiros Morato de
- Arantes Murilo Sérgio
- Araujo Andréa Cardoso de
- Araujo Helder Farias Pereira de
- Araújo-Lima Vitor
- Assis Julia Camara de
- Banks-Leite Cristina
- Baptista Michelle Noronha da Matta
- Barcik Jean Júnior
- Bettio Maurício
- Bispo Arthur Ângelo
- Bobato Rafaela
- Bochio Gabriela Menezes
- Bonetti Giselle Evelise
- Bosenbecker Camila
- Bovo Alex A.A.
- Braga Talita Vieira
- Bugoni Leandro
- Calsavara Larissa Corsini
- Camargo Barbosa Karlla Vanessa de
- Camargo Guaraldo André de
- Camargo Bruna Betagni de
- Carrano Eduardo
- Carvalho Maria Amélia Santos de
- Cavarzere Vagner
- Cerboncini Ricardo Augusto Serpa
- Cestari César
- Cezila Beatriz Azevedo
- Chaves Flávia Guimarães
- Costa Leonardo Marques
- Costa Thiago Vernaschi Vieira da
- Crestani Ana Cristina Vara
- Câmara Thanyria Pollyneide França
- Cândia-Gallardo Carlos Ernesto
- de Castro Pena João Carlos
- Deconto Leonardo Rafael
- Dias Rafael Antunes
- Donatelli Reginaldo José
- Doná Eder Afonso
- Duca Charles
- Efe Márcio Amorim
- Enedino Thayz Rodrigues
- Espínola Cid Rodrigo Rodriguez
- Falcon José Eduardo Teixeira
- Faria Deborah Maria
- Faria Fernando Azevedo
- Faria Rogério Rodrigues
- Farias Fernando Bittencourt de
- Faxina Claudenice
- Ferraz Kátia Maria Paschoaletto Micchi de Barros
- Ferreira Ariane
- Ferreira Carolina Demetrio
- Fischer Erich
- Fonseca Renata Cristina Batista
- Fontana Carla Suertegaray
- Francisco Mercival Roberto
- Freitas Fernando José Ferneda
- Galetti Mauro
- Gaspar Lucas P.
- Gatto Cassiano Augusto Ferreira Rodrigues
- Giese Felipe Borba
- Girardi Fabiane
- Gonçalves Fernando
- Gonçalves Mariana Lopes
- Gusmão Reginaldo Farias de
- Hasui Érica
- Jacoboski Lucilene Inês
- Jahn Alex E.
- Jesus Shayana de
- Junior Pedro Manoel Galetti
- Just João Paulo Gava
- Kanda Claudia Zukeran
- Kohler Glauco
- Lacerda Raquel Caroline Alves
- Laps Rudi Ricardo
- Las-Casas Flor Maria Guedes
- Lau Ricardo
- Leandro-Silva Victor
- Lima Favaro Fernando de
- Lima M. R.
- Lopes Leonardo Esteves
- Lugarini Camile
- Luz Daniela Tomasio Apolinario da
- Lyra Ricardo Brioschi
- Macario Phoeve
- Macarrão Arthur
- Machado Caio Graco
- Manica Lilian Tonelli
- Mariz Daniele
- Marques-Santos Fernando
- Martello Felipe
- Martins-Silva Jimi
- Mathias Leonardo B.
- Medolago César Augusto Bronzato
- Melo Marcos Antônio
- Menezes Gregório dos Reis
- Menezes Ícaro
- Metzger Jean Paul
- Meurer Rafael
- Meyer Douglas
- Meyer Marcela Afonso P.
- Missagia Caio C.C.
- Molin Tamara
- Monteiro Erison C.S.
- Morante-Filho José Carlos
- Moreno Daniele Janina
- Muylaert Renata L.
- Naka Luciano Nicol?s
- Namba Sumiko
- Neto Paulo Affonso Fonseca Pires
- Nunes Cristiane Estrêla Campodonio
- Nunes Maria Flavia Conti
- Ogrzewalska Maria Halina
- Oliveira Fratoni Rafael de
- Oliveira Lunardi Vitor de
- Oliveira Vanessa Cristina de
- Oshima Júlia Emi Faria
- Paes-Macarrão Natalia Dantas
- Paolino Roberta Montanheiro
- Persegona Jaqueline Evelyn
- Petronetto Adeliane Peterle
- Pichorim Mauro
- Piratelli Augusto J.
- Pizo Marco Aurélio
- Plucenio Gustavo Piletti
- Prates Cristine
- Provinciato Ivan Celso Carvalho
- Rajão Henrique
- Regolin André Luis
- Repenning Márcio
- Ribeiro Bianca Costa
- Ribeiro Milton Cezar
- Ribeiro Pedro Henrique Lima
- Rodrigues Licléia da Cruz
- Rodrigues Marcos
- Rodrigues Roberta Costa
- Rodrigues Rodolpho Credo
- Romagna Rafael Spilere
- Roos Andrei L.
- Roper James J.
- Rosa Gabriel Lima Medina
- Rosoni Jonas Rafael Rodrigues
- Ruiz Nicolás Luciano
- Saint-Clair Rafael S.
- Santos Andressa Hartuiq dos
- Schaedler Laura Maria
- Serafini Patrícia Pereira
- Shibuya Felipe L.S.
- Silva Elsimar Silveira da
- Silva José Nilton da
- Silveira Luis Fabio
- Silveira Natalia Stefanini da
- Souza Elivan Arantes de
- Souza-Correia Jozélia Maria de
- Tarso Zuquim de Antas Paulo de
- Tavares-Damasceno João Paulo
- Toledo-Lima Guilherme Santos
- Tonetti Vinicius R.
- Torre Gabriel Massaccesi de La
- Torres Ingrid Maria Denóbile
- Uezu Alexandre
- Vallejos Marcelo Alejandro Villegas
- Vasconcelos Marcelo Ferreira de
- Vecchi Maurício Brandão
- Viana Anderson Durão
- Viana Ivan Réus
- Vieira-Filho Arnaldo Honorato
- Willrich Guilherme
- Wischhoff Uschi
- Zocche Jairo José
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2019
- Field of study
Scientists have long been trying to understand why the Neotropical region holds the highest diversity of birds on Earth. Recently, there has been increased interest in morphological variation between and within species, and in how climate, topography, and anthropogenic pressures may explain and affect phenotypic variation. Because morphological data are not always available for many species at the local or regional scale, we are limited in our understanding of intra- and interspecies spatial morphological variation. Here, we present the ATLANTIC BIRD TRAITS, a data set that includes measurements of up to 44 morphological traits in 67,197 bird records from 2,790 populations distributed throughout the Atlantic forests of South America. This data set comprises information, compiled over two centuries (1820–2018), for 711 bird species, which represent 80% of all known bird diversity in the Atlantic Forest. Among the most commonly reported traits are sex (n = 65,717), age (n = 63,852), body mass (n = 58,768), flight molt presence (n = 44,941), molt presence (n = 44,847), body molt presence (n = 44,606), tail length (n = 43,005), reproductive stage (n = 42,588), bill length (n = 37,409), body length (n = 28,394), right wing length (n = 21,950), tarsus length (n = 20,342), and wing length (n = 18,071). The most frequently recorded species are Chiroxiphia caudata (n = 1,837), Turdus albicollis (n = 1,658), Trichothraupis melanops (n = 1,468), Turdus leucomelas (n = 1,436), and Basileuterus culicivorus (n = 1,384). The species recorded in the greatest number of sampling localities are Basileuterus culicivorus (n = 243), Trichothraupis melanops (n = 242), Chiroxiphia caudata (n = 210), Platyrinchus mystaceus (n = 208), and Turdus rufiventris (n = 191). ATLANTIC BIRD TRAITS (ABT) is the most comprehensive data set on measurements of bird morphological traits found in a biodiversity hotspot; it provides data for basic and applied research at multiple scales, from individual to community, and from the local to the macroecological perspectives. No copyright or proprietary restrictions are associated with the use of this data set. Please cite this data paper when the data are used in publications or teaching and educational activities. © 2019 The Authors. Ecology © 2019 The Ecological Society of Americ
Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19
- Author
- Abdukahil heryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Abrous Amal
- Absil Lara
- Acker Andrew
- Adachi Shingo
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Airlangga Eka
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Akwani Chika
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alberti Angela
- Alegesan Senthilkumar
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ampaw Phoebe
- Andini Roberto
- Andrey
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Antunes de Brito Carlos Alexandre
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asensio Angel
- Ashraf Muhammad
- Assie Jean Baptiste
- Asyraf Amirul
- Atif Minahel
- Atikah Ahmad Ridzuan Siti Nurul
- Atique Anika
- Auchabie Johann
- Aumaitre Hugues
- Auvet Adrien
- Ayadi Kamaluddin Muhammad Aisar
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baillie J. Kenneth
- Baird J Kevin
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Balan Valeria
- Balazote Pablo Serrano
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S.
- Barnett Saef Umar
- Barnikel Michaela
- Barrelet Audrey
- Barrigoto Cleide
- Barrio Noelia García
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Bautista Rincon Diego Fernando
- Beane Abigail
- Bedossa Alexandra
- Bee Ker Hong
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Benech Nicolas
- Benjiman Lionel Eric
- Benkerrou Dehbia
- Bennett Suzanne
- Benny Binny
- Bento Luís
- Berdal Jan-Erik
- Bergeaud Delphine
- Bergin Hazel
- Bermejo Carlos Lumbreras
- Bernal Sobrino José Luis
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bidin Farah Nadiah
- Bin Kamarudin Mohd Nazlin
- Binti Mohd Yakop Siti Rohani
- Binti Zaidan Nor Zaila
- Bisoffi Zeno
- Bissuel François
- Biston Patrick
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Blumberg Lucille
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Borges Diogo
- Borie Raphaël
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller Kévin
- Bouillet Laurence
- Bouisse Camile
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando Augusto
- Braconnier Axelle
- Braga Cynthia
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brewster David
- Brickell Kathy
- Brien Fionnuala O.
- Browne Shaunagh
- Brusse-Keizer Marjolein
- Bryda Petra
- Buchtele Nina
- Bugaeva Polina
- Buisson Marielle
- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G.
- Butnaru Denis
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O.
- Calligy Kate
- Calvache Jose Andres
- Campana Valentine
- Campbell Paul
- Campisi Josie
- Camões João
- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castor-Alexandre Guylaine
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
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- Greenhalf William
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- Harrison Ewen M.
- Harrison Janet
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- Hough Catherine L.
- Houltham Stuart
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- Hulot Jean-Sébastien
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- Johnson David W.
- Jorge García Ruth N.
- Joseph Cédric
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- Loschner Anthony L.
- Loubet Paul
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- Low Lee
- Lowik Marije
- Loy Jia Shyi
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- Luna Carlos M.
- Lungu Olguta
- Lunn Miles
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- Malfertheiner Maximilian
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- McLean Kenneth A.
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- Ogura Takayuki
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- Oliveira João
- Olliaro Piero L.
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- Payen Jean-François
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- Sukumar Prasanth
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- Supic Dubravka
- Suppiah Deepashankari
- Surovcová Magdalena
- Svistunov Suwarti
- Sweeney Lisa Mc
- Syahrin Sarah
- Syrigos Konstantinos
- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Tabrizi Shirin
- Taccone Fabio S.
- Tagherset Lysa
- Taib Shahdattul Mawarni
- Taleb Sara
- Talsma Jelmer
- Tamlihat Younes Ait
- Tampubolon Maria Lawrensia
- Tan Kim Keat
- Tan Yan Chyi
- Tanaka Hiroyuki
- Tanaka Taku
- Taniguchi Hayato
- Tardivon Coralie
- Tattevin Pierre
- Taufik M Azhari
- Tawfik Hassan
- Tedder Richard S.
- Tee Tze Yuan
- Teixeira João
- Tellier Marie-Capucine
- Teoh Sze Kye
- Teotonio Vanessa
- Terpstra Pleun
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- Terzi Nicolas
- Tessier-Grenier Hubert
- Tey Adrian
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- Thanga Thurai Surain Raaj
- Thangavelu Suvintheran
- Theron Elmi
- Thibault Vincent
- Thiberville Simon-Djamel
- Thill Benoît
- Thirumanickam Jananee
- Tho Leong Chin
- Thompson Shaun
- Thomson David
- Thomson Emma C.
- Thorpe Mathew
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tirupakuzhi Vijayaraghavan Bharath Kumar
- Tissot Noémie
- Toal Fiona
- Toki Maria
- Tonby Kristian
- Tonnii Sia Loong
- Torre Marta
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- Torres-Zevallos Hernando
- Towers Michael
- Trapani Tony
- Tromeur Cécile
- Trontzas Ioannis
- Trouillon Tiffany
- Truong Jeanne
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turgeon Alexis F.
- Turmel Jean-Marie
- Turtle Lance C. W.
- Tveita Anders
- Twardowski Pawel
- Téoulé François
- Udy Andrew
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M.
- Vajdovics Cristinava
- Val-Flores Luís
- Valran Amélie
- Van de Velde Stijn
- van den Berge Marcel
- van der Palen Job
- van der Valk Paul
- Van Der Vekens Nicky
- Van der Voort Peter
- Van Der Werf Sylvie
- van Gulik Laura
- Van Hattem Jarne
- van Netten Carolien
- van Veen Ilonka
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Varrone Michael
- Vasudayan Shoban Raj
- Vauchy Charline
- Vecham Pavan Kumar
- Veeran Shaminee
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vidal José Ernesto
- Vieira César
- Villanueva Joy Ann
- Villoldo Andrea
- Visseaux Benoit
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Wainstein Marina
- Walsh Laura
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Wen Tan Pei
- Wesselius Sanne
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Bailey
- Williams Patricia J.
- Williams Virginie
- Wils Evert-Jan
- Wittman Jessica
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Xian Gan Ee
- Xian Lim Saio
- Xynogalas Ioannis
- Yamazaki Masaki
- Yang Toh Jordan Zhien
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Zaaqoq Akram
- Zabbe Marion
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Elsevier BV
- Publication date
- 26/05/2023
- Field of study
Introduction: Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining the relationship between COVID-19 and AKI in low- and low-middle income countries (LLMIC) are lacking. Given that AKI is known to carry a higher mortality rate in these countries, it is important to understand differences in this population. Methods: This prospective, observational study examines the AKI incidence and characteristics of 32,210 patients with COVID-19 from 49 countries across all income levels who were admitted to an intensive care unit during their hospital stay. Results: Among patients with COVID-19 admitted to the intensive care unit, AKI incidence was highest in patients in LLMIC, followed by patients in upper-middle income countries (UMIC) and high-income countries (HIC) (53%, 38%, and 30%, respectively), whereas dialysis rates were lowest among patients with AKI from LLMIC and highest among those from HIC (27% vs. 45%). Patients with AKI in LLMIC had the largest proportion of community-acquired AKI (CA-AKI) and highest rate of in-hospital death (79% vs. 54% in HIC and 66% in UMIC). The association between AKI, being from LLMIC and in-hospital death persisted even after adjusting for disease severity. Conclusions: AKI is a particularly devastating complication of COVID-19 among patients from poorer nations where the gaps in accessibility and quality of healthcare delivery have a major impact on patient outcomes
Liver injury in hospitalized patients with COVID-19: An International observational cohort study
- Author
- Abby Hurd
- Abdulrahman Al-Fares
- Abhijit Duggal
- Abigail Beane
- Adam Hall
- Adam Nowinski
- Adhikari Neill K. J.
- Adrian Streinu-Cercel
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Agnès Meybeck
- Agnès Sommet
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Aidan Burrell
- Ailbhe Hayes
- Aine McCarthy
- Aisling Gavin
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Al-Fares Abdulrahman
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Albert Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martín-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Notari
- Alex Nagrebetsky
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J. Mentzer
- Alexander King
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Ali Ait Hssain
- Ali Hachemi
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Aline-Marie Florence
- Alison M. Meynert
- Alistair Nichol
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- Amal Abrous
- Amanda Corley
- Amanda Palacios
- Amanda Rojek
- Amandine Gagneux-Brunon
- Amar Bhatt
- Amélie Valran
- Ami Stuart
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amy Lester-Grant
- Amy Stone
- Ana Chora Sousa
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Ana Isabel de Pinho Oliveira
- Ana L Rios
- Ana Martins
- Ana Motos
- Ana Raquel Maia
- Anant Kataria
- Anatoliy Gavrylov
- Anca Streinu-Cercel
- Anders Tveita
- Andra-Maris Post
- Andrea Angheben
- Andrea Cortegiani
- Andrea Dell’Amore
- Andrea Kelly
- Andrea Rossanese
- Andrea Villoldo
- Andreas Lind
- Andrew Acker
- Andrew Dagens
- Andrew Hershey
- Andrew Law
- Andrew Udy
- Andrey Svistunov
- André Cabie
- André Roberto
- Andriy Bal
- Angela Alberti
- Anika Atique
- Anilawati Mat Jelani
- Anissa Chair
- Anja Grosse Lordemann
- Anjellica Chen
- Anna Beltrame
- Anna Ciullo
- Anna Greti Everding
- Anna Jung
- Anne Conrad
- Anne Guillaumot
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne-Hélène Boivin
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annelies Verbon
- Annemarie B. Docherty
- Annmarie O Callaghan
- Annmarie O’Callaghan
- Ansley Hamer
- Anthony L. Loschner
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Anton Prinssen
- Antoni Torres
- Antonia Ho
- Antonio Arcadipane
- Antonio Pesenti
- António Mesquita
- Aquiles Henriquez
- Ardiyan Apriyana
- Arfan Ikram
- Argin G
- Arianne Joy Corpuz
- Arie Zainul Fatoni
- Arnaud Scherpereel
- Arsène Kpangon
- Arthur Garan
- Ary Serpa Neto
- Asad Usman
- Asfia Sultana
- Asgar Rishu
- Asim Rana
- Asma Moin
- Audrey Barrelet
- Aurélie Papadopoulos
- Aurélie Veislinger
- Aurélie Wiedemann
- Aurore Bousquet
- Axelle Braconnier
- Azlan Mat Soom
- Bailey Cassandra
- Bairbre McNicholas
- Bambang Pujo Semedi
- Barbara Wanjiru Citarella
- Baruch Joaquin
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- Benigno Ferreira
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- Benjamine Sarton
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- Bertrand Dussol
- Bénédicte Lefebvre
- Bénédicte Rossignol
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- Nidyanara Castanheira
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- Nilar Lwin
- Nina Buchtele
- Nina Jamieson
- Nobuya Kitamura
- Noémie Mercier
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- Paddy Mallon
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- Paula Custodio
- Pauline Caraux-Paz
- Pavan Kumar Vecham
- Pedro Faria
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- Ritika Ranjan
- Rob Klont
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- Roberta Cavalin
- Roberto Roncon-Albuquerque Jr
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- Rodrigo Diaz
- Rogério Silva
- Rolando Claure-Del Granado
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- Rupert Higgins
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- Saef Umar Barnett
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- Senthilkumar Alegesan
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- Sérgio Gaião
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- Shaminee Veeran
- Sharma Keshav
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- Shaunagh Browne
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- Sheryl Ann Abdukahil
- Shiranee Sriskandan
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- Shoban Raj Vasudayan
- Shona C. Moore
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- Soizic Le Mestre
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- Stéphanie Fry
- Stijn Van de Velde
- Stuart Houltham
- Su Hwan Lee
- Subbarao Elapavaluru
- Sudhir Krishnan
- Sue Smith
- Suhaila Abdul Wahab
- Surain Raaj Thanga Thurai
- Suresh Kumar Chidambaram
- Surya Otto Wijaya
- Susana Fernandes
- Susanne Dudman
- Sushil Khanal
- Suvintheran Thangavelu
- Suzanne Bennett
- Suzette Willems
- Syamin Asyraf Shahidan
- Sybille Bevilcaqua
- Sylvain Diamantis
- Sylvie Behilill
- Sylvie LeGac
- Sylvie Lion-Daolio
- Sylvie Van Der Werf
- Synne Jenum
- Sze Kye Teoh
- Taccone Fabio Silvio
- Tae Song
- Tahira Jamal Mohamed
- Takako Akimoto
- Taku Tanaka
- Tala Al-dabbous
- Tan Pei Wen
- Tarek Elshazly
- Tatiana Fonseca
- Tawnya Ogston
- Tânia Sequeira
- Teck Fung Wong
- Teresa Lawrence
- Terese Hammond
- Tharmini Ravi
- Thavamany Kaleesvran
- Théo Trioux
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomas Staudinger
- Thushan de Silva
- Tiago Isidoro
- Tiago Reyes
- Tiffany Trouillon
- Timothy M. Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Tirupakuzhi Vijayaraghavan Bharath Kumar
- Tjard Schermer
- Todd C. Lee
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Toni Duculan
- Tony Trapani
- Toshiki Yokoyama
- Triona Downer
- Tristan Gigante
- Trude Steinsvik
- Tze Vee Soh
- Tze Yuan Tee
- Vadim Tieroshyn
- Valentine Campana
- Valentine Piquard
- Valeria Balan
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Valla Sahraei
- Vanessa Sancho-Shimizu
- Vanina Meysonnier
- Ventzislava Petrov-Sanchez
- Vera Irawany
- Véronique Lemee
- Vicente Souza-Dantas
- Victor Fomin
- Victoria Manda
- Victoria Shaw
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Waasila Jassat
- Walter Picard
- Wei Han Hoh
- Wei Shen Lim
- Wendy S. Barclay
- William A. Paxton
- William Dechert
- William Greenhalf
- Wilna Oosthuyzen
- Wim Dieperink
- Xavier Duval
- Xin Ci Wong
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yves Levy
- Zhang Duan Tham
- Zul Amali Che Kamaruddin
- Zulfiqar Sandhu
- Publication venue
- PUBLIC LIBRARY SCIENCE
- Publication date
- 01/10/2023
- Field of study
Background: Using a large dataset, we evaluated prevalence and severity of alterations in liver enzymes in COVID-19 and association with patient-centred outcomes.MethodsWe included hospitalized patients with confirmed or suspected SARS-CoV-2 infection from the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) database. Key exposure was baseline liver enzymes (AST, ALT, bilirubin). Patients were assigned Liver Injury Classification score based on 3 components of enzymes at admission: Normal; Stage I) Liver injury: any component between 1-3x upper limit of normal (ULN); Stage II) Severe liver injury: any component & GE;3x ULN. Outcomes were hospital mortality, utilization of selected resources, complications, and durations of hospital and ICU stay. Analyses used logistic regression with associations expressed as adjusted odds ratios (OR) with 95% confidence intervals (CI).ResultsOf 17,531 included patients, 46.2% (8099) and 8.2% (1430) of patients had stage 1 and 2 liver injury respectively. Compared to normal, stages 1 and 2 were associated with higher odds of mortality (OR 1.53 [1.37-1.71]; OR 2.50 [2.10-2.96]), ICU admission (OR 1.63 [1.48-1.79]; OR 1.90 [1.62-2.23]), and invasive mechanical ventilation (OR 1.43 [1.27-1.70]; OR 1.95 (1.55-2.45). Stages 1 and 2 were also associated with higher odds of developing sepsis (OR 1.38 [1.27-1.50]; OR 1.46 [1.25-1.70]), acute kidney injury (OR 1.13 [1.00-1.27]; OR 1.59 [1.32-1.91]), and acute respiratory distress syndrome (OR 1.38 [1.22-1.55]; OR 1.80 [1.49-2.17]).ConclusionsLiver enzyme abnormalities are common among COVID-19 patients and associated with worse outcomes
Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry
- Author
- Abdukahil Sheryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Abrous Amal
- Absil Lara
- Acker Andrew
- Adam Elisabeth
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Akwani Chika
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alberti Angela
- Alegesan Senthilkumar
- Alessi Marta
- Alex Beatrice
- Alexander Peta MA
- Alexandre Kévin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ampaw Phoebe
- Andini Roberto
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asensio Angel
- Ashraf Muhammad
- Assie Jean Baptiste
- Asyraf Amirul
- Atif Minahel
- Atikah Ahmad Ridzuan Siti Nurul
- Atique Anika
- Auchabie Johann
- Aumaitre Hugues
- Auvet Adrien
- Ayadi Kamaluddin Muhammad Aisar
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie J Kenneth
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Balan Valeria
- Balazote Pablo Serrano
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S
- Barnett Saef Umar
- Barnikel Michaela
- Barrasa Helena
- Barrelet Audrey
- Barrigoto Cleide
- Barrio Noelia García
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Basri Muhammad Fadhli Hassin
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Beane Abigail
- Bedossa Alexandra
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Benech Nicolas
- Benjiman Lionel Eric
- Benkerrou Dehbia
- Bennett Suzanne
- Benny Binny
- Bento Luís
- Berdal Jan-Erik
- Bergeaud Delphine
- Bergin Hazel
- Bermejo Carlos Lumbreras
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bidin Farah Nadiah
- Binti Mohd Yakop Siti Rohani
- Binti Zaidan Nor Zaila
- Bisoffi Zeno
- Bissuel François
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Blumberg Lucille
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Borges Diogo
- Borie Raphaël
- Bosse Hans Martin
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller Kévin
- Bouillet Laurence
- Bouisse Camile
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando Augusto
- Bozza Patricia T
- Braconnier Axelle
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brewster David
- Brickell Kathy
- Brien Fionnuala O
- Browne Alex
- Browne Shaunagh
- Brozzi Nicolas
- Brusse-Keizer Marjolein
- Bryda Petra
- Buchtele Nina
- Buisson Marielle
- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O
- Calligy Kate
- Calvache Jose Andres
- Campana Valentine
- Campbell Paul
- Campisi Josie
- Camões João
- Canepa Cecilia
- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavayas Alexandros
- Cely Lina Morales
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chantalat Auger Christelle
- Chapplain Jean-Marc
- Charpentier Charlotte
- Chas Julie
- Che Kamaruddin Zul Amali
- Chen Anjellica
- Chen Yih-Sharng
- Chenard Léo
- Cheng Matthew Pellan
- Cheret Antoine
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chidambaram Suresh Kumar
- Chin Tho Leong
- Chirouze Catherine
- Chiumello Davide
- Cho Sung-Min
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chopin Marie-Charlotte
- Chow Ting Soo
- Chua Hiu Jian
- Chua Jonathan
- Chávez Iñiguez Jonathan Samuel
- Cidade Jose Pedro
- Cisneros Herreros José Miguel
- Citarella Barbara Wanjiru
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Emma
- Clarke Jennifer
- Claure-Del Granado Rolando
- Clohisey Sara
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Coles Jennifer
- Coles Megan
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Combs Pamela
- Connolly Jennifer
- Connor Marie
- Conrad Anne
- Conway Elaine
- Cooke Graham S
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cornelis Sabine
- Cornet Alexander Daniel
- Corpuz Arianne Joy
- Cortegiani Andrea
- Corvaisier Grégory
- Costigan Emma
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Cregan Rachel
- Cristella Cosimo
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Bermúdez Juan Luis
- Cruz Rojo Jaime
- Cruz Claudina
- Csete Marc
- Cullen Ailbhe
- Cummings Matthew
- Curley Gerard
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- Cárcel Sheila
- D'Aragon Frédérick
- D'Ortenzio Eric
- da Silva Filipe Ana
- Da Silva Fernanda Dias
- Da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew
- Dahly Darren
- Dalton Heidi
- Dalton Heidi
- Dalton Jo
- Daly Seamus
- Damas Juliana
- Daneman Nick
- Daniel Corinne
- Dankwa Emmanuelle A
- Dantas Jorge
- de Brito Carlos Alexandre Antunes
- de Castro Maisa Guimarães
- de Jong Menno
- de la Calle Guillermo Maestro
- de Loughry Gillian
- De Montmollin Etienne
- de Oliveira França Rafael Freitas
- de Piero Maria
- de Pinho Oliveira Ana Isabel
- De Rosa Rosanna
- de Silva Thushan
- de Vries Peter
- Dean David
- Debard Alexa
- DeBenedictis Bianca
- Debray Marie-Pierre
- DeCastro Nathalie
- Dechert William
- Deconninck Lauren
- Decours Romain
- Defous Eve
- Delacroix Isabelle
- Delaveuve Eric
- Delavigne Karen
- Delfos Nathalie M
- Deligiannis Ionna
- Dell'Amore Andrea
- Delmas Christelle
- Delobel Pierre
- Delsing Corine
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Desai Mehul
- Descamps Diane
- Desvallées Mathilde
- Devouge Eglantine Ferrand
- Dewayanti Santi
- Dhanger Pathik
- Diallo Alpha
- Diamantis Sylvain
- Dias André
- Diaz Juan Jose
- Diaz Priscila
- Diaz Rodrigo
- Didier Kévin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet Jérôme
- Dinot Vincent
- Diop Fara
- Diouf Alphonsine
- Dishon Yael
- Djossou Félix
- Docherty Annemarie B
- Doherty Helen
- Donnelly Christl A
- Donnelly Maria
- Donohue Chloe
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival Céline
- Douglas James Joshua
- Dournon Nathalie
- Downer Triona
- Downey Joanne
- Downing Mark
- Drake Tom
- Driscoll Aoife
- Dryden Murray
- Dubee Vincent
- Dubos François
- Ducancelle Alexandre
- Duculan Toni
- Dudman Susanne
- Duggal Abhijit
- Dunand Paul
- Dunning Jake
- Duplaix Mathilde
- Durante-Mangoni Emanuele
- Durham Lucian
- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- Ean Sim Choon
- Echeverria-Villalobos Marco
- Eddington Devin P
- Egan Siobhan
- Eira Carla
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- El Sanharawi Mohammed
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- Everding Anna Greti
- Evers Mirjam
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- Fabre Marc
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron J
- Fanning Jonathon P
- Faria Pedro
- Fateena Hanan
- Fatoni Arie Zainul
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- Fayed Mohamed
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- Foley Jean
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- Forsyth Simon
- Foster Denise
- Foti Giuseppe
- Fourn Erwan
- Fowler Robert A
- Fraher Marianne
- Franch-Llasat Diego
- Fraser Christophe
- Fraser John
- Fraser John F
- Freire Marcela Vieira
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- Fry Stéphanie
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- Granier Pascal
- Grasselli Giacomo
- Green Christopher A
- Greene Courtney
- Greenhalf William
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- Griffee Matthew
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- Griffiths Fiona
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- Groenendijk Albert
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- Joseph Cédric
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- Komatsu Mamoru
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- Loschner Anthony L
- Loubet Paul
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- Lucet Jean-Christophe
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- Maia Ana Raquel
- Maier Lars S
- Maillet Mylène
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- McConnochie Rachael
- McDermott Sherry
- McDonald Sarah E
- McElroy Aine
- McElwee Samuel
- McEneany Victoria
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- McGeer Allison
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- McNally Paul
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- Mechlin Maggie
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- Mercier Emmanuelle
- Mercier Noémie
- Merckx Antoine
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- Merson Laura
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- Meynert Alison M
- Meysonnier Vanina
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- Oh Tak-Hyuk
- Ohshimo Shinichiro
- Oliveira João
- Oliveira Larissa
- Olliaro Piero L
- Ong David SY
- Ong Jee Yan
- Oosthuyzen Wilna
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- Openshaw Peter
- Orozco-Chamorro Claudia Milena
- Ortoleva Jamel
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- Paul Christelle
- Paul Mical
- Paulos Jorge
- Paxton William A
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- Peake Sandra L
- Peariasamy Kalaiarasu
- Peek Giles J
- Peelman Florent
- Peiffer-Smadja Nathan
- Peigne Vincent
- Pejkovska Mare
- Pelosi Paolo
- Peltan Ithan D
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- Post Andra-Maris
- Postma Douwe F
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- Powis Jeff
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- Preau Sébastien
- Prebensen Christian
- Preiser Jean-Charles
- Prinssen Anton
- Pritchard Mark G
- Proença Lucia
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- Purcell Gregory
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- Richardson David
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- Richier Laurent
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- Rios Ana L
- Rishu Asgar
- Rispal Patrick
- Risso Karine
- Rizer Nicholas
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- Robineau Olivier
- Roche-Campo Ferran
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- Schroll Stephan
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- Scicluna Brendan
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- Scott-Brown James
- Sedillot Nicholas
- Seitz Tamara
- Selvarajoo Mageswari
- Semaille Caroline
- Semedi Bambang Pujo
- Semple Malcolm G
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- Senneville Eric
- Sepulveda Claudia
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- Sequeira Tânia
- Shadowitz Ellen
- Shahidan Syamin Asyraf
- Shamsah Mohammad
- Sharjeel Shaikh
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- Shaw Catherine A
- Shaw Victoria
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- Shi Haixia
- Shime Nobuaki
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- Sukumar Prasanth
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- Syahrin Sarah
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- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Tabrizi Shirin
- Taccone Fabio S
- Tagherset Lysa
- Taib Shahdattul Mawarni
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- Tampubolon Maria Lawrensia
- Tan Kim Keat
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- Tardivon Coralie
- Tattevin Pierre
- Taufik M Azhari
- Tawfik Hassan
- Tedder Richard S
- Tee Tze Yuan
- Teixeira João
- Tejada Sofia
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- Teoh Sze Kye
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- Thill Benoît
- Thirumanickam Jananee
- Thompson Shaun
- Thomson David
- Thomson Emma C
- Thorpe Mathew
- Thwaites Ryan S
- Tierney Paul
- Tieroshyn Vadim
- Timsit Jean-François
- Tissot Noémie
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- Truong Jeanne
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- Turmel Jean-Marie
- Turtle Lance CW
- Tveita Anders
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- Téoulé François
- Uchiyama Makoto
- Udy Andrew
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M
- Vajdovics Cristinava
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- Wahid Nadirah Abdul
- Wainstein Marina
- Walsh Laura
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Weil Katharina
- Wen Tan Pei
- Wesselius Sanne
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Bailey
- Williams Patricia J
- Williams Virginie
- Wils Evert-Jan
- Wittman Jessica
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Xian Gan Ee
- Xian Lim Saio
- Xynogalas Ioannis
- Yamazaki Masaki
- Yang Toh Jordan Zhien
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Zaaqoq Akram
- Zabbe Marion
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Elsevier BV
- Publication date
- 30/06/2023
- Field of study
Background: COVID-19 has been associated with a broad range of thromboembolic, ischemic, and hemorrhagic complications (coagulopathy complications). Most studies have focused on patients with severe disease from high-income countries (HICs). Objectives: The main aims were to compare the frequency of coagulopathy complications in developing countries (low- and middle-income countries [LMICs]) with those in HICs, delineate the frequency across a range of treatment levels, and determine associations with in-hospital mortality. Methods: Adult patients enrolled in an observational, multinational registry, the International Severe Acute Respiratory and Emerging Infections COVID-19 study, between January 1, 2020, and September 15, 2021, met inclusion criteria, including admission to a hospital for laboratory-confirmed, acute COVID-19 and data on complications and survival. The advanced-treatment cohort received care, such as admission to the intensive care unit, mechanical ventilation, or inotropes or vasopressors; the basic-treatment cohort did not receive any of these interventions. Results: The study population included 495,682 patients from 52 countries, with 63% from LMICs and 85% in the basic treatment cohort. The frequency of coagulopathy complications was higher in HICs (0.76%-3.4%) than in LMICs (0.09%-1.22%). Complications were more frequent in the advanced-treatment cohort than in the basic-treatment cohort. Coagulopathy complications were associated with increased in-hospital mortality (odds ratio, 1.58; 95% CI, 1.52-1.64). The increased mortality associated with these complications was higher in LMICs (58.5%) than in HICs (35.4%). After controlling for coagulopathy complications, treatment intensity, and multiple other factors, the mortality was higher among patients in LMICs than among patients in HICs (odds ratio, 1.45; 95% CI, 1.39-1.51). Conclusion: In a large, international registry of patients hospitalized for COVID-19, coagulopathy complications were more frequent in HICs than in LMICs (developing countries). Increased mortality associated with coagulopathy complications was of a greater magnitude among patients in LMICs. Additional research is needed regarding timely diagnosis of and intervention for coagulation derangements associated with COVID-19, particularly for limited-resource settings
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods
- Author
- Abdukahil Sheryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Abreu Julia Rodriguez
- Abrous Amal
- Absil Lara
- Acker Andrew
- Adachi Shingo
- Adam Elisabeth
- Adriano Enrico
- Adrião Diana
- Ageel Saleh Al
- Ahmed Shakeel
- Aiello Marina
- Ainscough Kate
- Airlangga Eka
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alberti Angela
- Alegesan Senthilkumar
- Alegre Cynthia
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alfoudri Huda
- Ali Adam
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ammerlaan Heidi
- Ampaw Phoebe
- Andini Roberto
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Anwar Kazi Rubayet
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asaki Motohiro
- Asensio Angel
- Ashley Elizabeth A.
- Ashraf Muhammad
- Assie Jean Baptiste
- Asyraf Amirul
- Atique Anika
- Attanyake AM Udara Lakshan
- Auchabie Johann
- Auger Christelle Chantalat
- Aumaitre Hugues
- Auvet Adrien
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie J. Kenneth
- Baird J Kevin
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Balan Valeria
- Banheiro Bruno Sarmento
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S.
- Barnett Saef Umar
- Barnikel Michaela
- Barrasa Helena
- Barrelet Audrey
- Barrigoto Cleide
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Basri Muhammad Fadhli Hassin
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Beane Abigail
- Bedossa Alexandra
- Bee Ker Hong
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Benech Nicolas
- Benjiman Lionel Eric
- Benkerrou Dehbia
- Bennett Suzanne
- Bento Luís
- Berdal Jan-Erik
- Berge Marcel van den
- Bergeaud Delphine
- Bergin Hazel
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Betz Adam
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bidin Farah Nadiah
- Bihan Clément Le
- Bisoffi Zeno
- Bissuel François
- Biston Patrick
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Blumberg Lucille
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Bonelli Patrizia
- Bonfasius Aurelius
- Borges Diogo
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- Bouadma Lila
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- Petrovic Michele
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- Phonemixay Ooyanong
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- Rajahram Giri Shan
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- Ramakrishnan Nagarajan
- Ramalho José
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- Rewa Oleksa
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- Trapani Tony
- Trieu Huynh Trung
- Trioux Théo
- Tromeur Cécile
- Trontzas Ioannis
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- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turgeon Alexis F.
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- Twardowski Pawel
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- Uchiyama Makoto
- Udayanga PG Ishara
- Udy Andrew
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- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M.
- Vajdovics Cristinava
- Val-Flores Luís
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- Valk Paul van der
- Valran Amélie
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- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Varrone Michael
- Vasconcelos Malte Kohns
- Vasudayan Shoban Raj
- Vauchy Charline
- Vecham Pavan Kumar
- Veen Ilonka van
- Veeran Shaminee
- Veislinger Aurélie
- Vekens Nicky Van Der
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vickers James
- Vidal José Ernesto
- Vieira César
- Villanueva Joy Ann
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Vishwanathan Gayatri
- Visseaux Benoit
- Visser Hannah
- Vitiello Chiara
- Vongsouvath Manivanh
- Vonkeman Harald
- Voort Peter Van der
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Webb Steve
- Wei Jia
- Weil Katharina
- Wen Tan Pei
- Werf Sylvie Van Der
- Wesselius Sanne
- West T. Eoin
- Wham Murray
- Whelan Bryan
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
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- Williams Virginie
- Willigen Hugo Van
- Wils Evert-Jan
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- Wong Teck Fung
- Wong Xin Ci
- Wong Xin Ci
- Wong Yew Sing
- Wright Natalie
- Xian Gan Ee
- Xian Lim Saio
- Xuan Kuan Pei
- Xynogalas Ioannis
- Yacoub Sophie
- Yakop Siti Rohani Binti Mohd
- Yamazaki Masaki
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yiaye Touxiong
- Yiu Ng Wing
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zabert Gustavo E
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zaidan Nor Zaila Binti
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zawadka Konrad
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Publication date
- 16/07/2024
- Field of study
By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 million deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples and with methodological limitations. It is highly important to develop predictive tools for pulmonary embolism (PE) in COVID-19 patients as one of the most severe preventable complications of COVID-19. Early recognition can help provide life-saving targeted anti-coagulation therapy right at admission. Using a dataset of more than 800,000 COVID-19 patients from an international cohort, we propose a cost-sensitive gradient-boosted machine learning model that predicts occurrence of PE and death at admission. Logistic regression, Cox proportional hazards models, and Shapley values were used to identify key predictors for PE and death. Our prediction model had a test AUROC of 75.9% and 74.2%, and sensitivities of 67.5% and 72.7% for PE and all-cause mortality respectively on a highly diverse and held-out test set. The PE prediction model was also evaluated on patients in UK and Spain separately with test results of 74.5% AUROC, 63.5% sensitivity and 78.9% AUROC, 95.7% sensitivity. Age, sex, region of admission, comorbidities (chronic cardiac and pulmonary disease, dementia, diabetes, hypertension, cancer, obesity, smoking), and symptoms (any, confusion, chest pain, fatigue, headache, fever, muscle or joint pain, shortness of breath) were the most important clinical predictors at admission. Age, overall presence of symptoms, shortness of breath, and hypertension were found to be key predictors for PE using our extreme gradient boosted model. This analysis based on the, until now, largest global dataset for this set of problems can inform hospital prioritisation policy and guide long term clinical research and decision-making for COVID-19 patients globally. Our machine learning model developed from an international cohort can serve to better regulate hospital risk prioritisation of at-risk patients
Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19
- Author
- A M Udara Lakshan Attanyake
- Aasiyah Rashan
- Aasmine Kaur
- Abby Hurd
- Abdulrahman Al-Fares
- Abhijit Duggal
- Abid Khatak
- Adam Ali
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Aftab Imtiaz
- Agamemnon Bakakos
- Agnieszka Oldakowska
- Agnès Meybeck
- Agnès Sommet
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Ailbhe Cullen
- Ailbhe Hayes
- Aine McCarthy
- Aine McElroy
- Aisha Kalsoom Mufti
- Aisling Gavin
- Aisling Murphy
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Alberto Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martin-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Notari
- Alex Browne
- Alex Nagrebetsky
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J Mentzer
- Alexander King
- Alexander Zoufaly
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Ali Ait Hssain
- Ali Hachemi
- Ali Liaquat
- Ali Raza
- Alice Bogaarts
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Alina Kalicinska
- Alison M Meynert
- Allegra Chatterjee
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- Amanda Corley
- Amanda Palacios
- Amandine Gagneux-Brunon
- Amar Bhatt
- Ami Stuart
- Amin Khawaja
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amy Hackmann
- Amy Lester-Grant
- Amy Stone
- Amélie Valran
- Ana Catarino
- Ana Chora Sousa
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Ana Isabel de Pinho Oliveira
- Ana L Rios
- Ana Marques
- Ana Martins
- Ana Motos
- Ana Raquel Maia
- Anand Thakur
- Anant Kataria
- Anatoliy Gavrylov
- Anders Benjamin Kildal
- Anders Tveita
- Andra-Maris Post
- Andre Real
- Andrea Angheben
- Andrea Cortegiani
- Andrea Dell'Amore
- Andrea Kelly
- Andrea Rossanese
- Andrea Villoldo
- Andreas Lind
- Andrew Acker
- Andrew Hershey
- Andrew Udy
- Andrey Svistunov
- Andriy Bal
- André Cabie
- André Dias
- André Roberto
- Andy Dong
- Andy Law
- Aneela Altaf
- Angel Asensio
- Angel Sanchez-Miralles
- Angela Alberti
- Anika Atique
- Anilawati Mat Jelani
- Anissa Chair
- Anja Grosse Lordemann
- Anjellica Chen
- Ankana Satya
- Anna Beltrame
- Anna Ciullo
- Anna Greti Everding
- Anna Jung
- Anne Conrad
- Anne Guillaumot
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne Opavsky
- Anne-Hélène Boivin
- Anne-Marie Guerguerian
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annelies Verbon
- Annemarie B Docherty
- Annmarie O Callaghan
- Annmarie O'Callaghan
- Ansley Hamer
- Anthony L Loschner
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Anton Prinssen
- Antoni Torres
- Antonia Ricchiuto
- Antonio Arcadipane
- Antonio Lalueza
- Antonio Loforte
- Antonio Pesenti
- António Mesquita
- Anuraj Shankar
- Aoife Driscoll
- Aoife Kelly
- Aquiles Henriquez-Trujillo
- Arabella Fahy
- Ardiyan Apriyana
- Arianne Joy Corpuz
- Arie Zainul Fatoni
- Arjen M Dondorp
- Arnaud Scherpereel
- Arsalan Rahutullah
- Arshad Taqi
- Arsène Kpangon
- Arthur Garan
- Ary Serpa Neto
- Asad Usman
- Asfia Sultana
- Asgar Rishu
- Ashraf Sheharyar
- Asim Rana
- Asma Moin
- Astarini Hidayah
- Atif Siddiqui
- Attaur Rehman
- Audrey Barrelet
- Aurelius Bonfasius
- Aurore Bousquet
- Aurélie Papadopoulos
- Aurélie Veislinger
- Aurélie Wiedemann
- Axelle Braconnier
- Ayodhia Pitaloka
- Azlan Mat Soom
- B P Sanka Ruwan Sri Darshana
- Bailey Cassandra
- Baillie J Kenneth
- Bairbre McNicholas
- Bambang Pujo Semedi
- Barrio Noelia García
- Baruch Joaquín
- Basanta Gauli
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- Patrick Imbert
- Patrick Rispal
- Patrick Rossignol
- Paul Campbell
- Paul Dunand
- Paul Henri Wicky
- Paul Kambiya
- Paul Klenerman
- Paul Le Turnier
- Paul Loubet
- Paul McNally
- Paul Tierney
- Paul van der Valk
- Paula Custodio
- Pauline Caraux-Paz
- Pauline Yeung Ng
- Pawel Twardowski
- Pedrera Jiménez Miguel
- Pedro Faria
- Pedro Povoa
- Perren J Cobb
- Peter de Vries
- Peter Doran
- Peter Kiiza
- Peter Openshaw
- Peter S Timashev
- Peter Van der Voort
- Petr Glybochko
- Petrovic Michele
- Phil Gallagher
- Philippe Jouvet
- Philippine Eloy
- Phoebe Ampaw
- Piero Valentini
- Pierre Delobel
- Pierre Jaquet
- Pierre Tattevin
- Pierre-Adrien Bolze
- Pierre-François Sandrine
- Pierre-Marc Villeneuve
- Pierre-Marie Roger
- Pieter Depuydt
- Piret Sillaots
- Pleun Terpstra
- Polina Bugaeva
- Pompini Agustina Sitompul
- Pooja Varghese
- Pramesh Sundar Shrestha
- Pranya Sakiyalak
- Pratap Karpayah
- Pratheema Ramachandran
- Praveen Kumar Ghisulal
- Priscila Diaz
- Pritchard Mark G
- Prompak Nitayavardhana
- Pulak Kedia
- Punam Singh
- Qabas Alkhafajee
- Quentin Le Hingrat
- Quentin Lepiller
- Quratul Ain Khan
- Rachael McConnochie
- Rachael Parke
- Rachel Cregan
- Rachida Ouissa
- Rafael Freitas de Oliveira França
- Rafael León
- Rafael Mahieu
- Rajavardhan Rangappa
- Rajesh Mohan Shetty
- Rajyabardhan Pattnaik
- Rakesh Arora
- Ramakrishnan Nagarajan
- Ramos Grazielle Viana
- Rana Imran Sikander
- Raph L Hamers
- Raphaël Borie
- Raphaël Favory
- Raquel Pinto
- Rashan Haniffa
- Rashid Nasim Khan
- Rasidah Bt Senian
- Raul Neto
- Razi Alalqam
- Rebecca Hamidfar
- Rebecca Holt
- Rebekha Garcia
- Renata Barbalho
- Renato Reis
- Renaud Tamisier
- Renee Douma
- Ricard Ferrer-Roca
- Ricardo Fritz
- Richard S Tedder
- Riinu Pius
- Rima Song
- Rita Alves
- Rita Hinchion
- Ritika Ranjan
- Rob Klont
- Robert A Fowler
- Roberta Cavalin
- Roberta Meta
- Roberto Andini
- Roberto Roncon-Albuquerque
- Robin Kobbe
- Rodrigo Diaz
- Roger Claire
- Rogério Silva
- Rohan Shetty
- Rojek Amanda
- Rolando Claure-Del Granado
- Romain Basmaci
- Romain Decours
- Romain Guery
- Roman Ullrich
- Romans Matulevics
- Rosanna De Rosa
- Rosario Maria Torres Santos-Olmo
- Ross Hendry
- Rostane Gaci
- Roxane Courtois
- Rozanah Abd Rahman
- Rui Gomes
- Rui Pereira
- Rumaisah Satyawati
- Rupert Higgins
- Ruth Jimbo-Sotomayor
- Ruth Lyons
- Ruth N Jorge García
- Ryadh Pokeerbux
- Ryan Kennedy
- Ryan Khoo
- Ryan S Thwaites
- Ryuzo Abe
- Saad Nseir
- Sabelline Bouchez
- Sabin Koirala
- Sabina Kali
- Sabina Mason
- Sabine Cornelis
- Sabine Croonen
- Sadie Kelly
- Saef Umar Barnett
- Saijad Orakzai
- Sairah Sadaf
- Sakshi Lath
- Saleh Al Ageel
- Sally Shrapnel
- Salma Jaafoura
- Samira Laribi
- Samreen Ijaz
- Samuel Bernard Ekow Harrison
- Samuel Hinton
- Samuel Markowicz
- Samuel McElwee
- Sandrine Couffin-Cadiergues
- Sandulescu Oana
- Sanjay Lakhey
- Sanne Wesselius
- Santi Dewayanti
- Saptadi Yuliarto
- Sara Clohisey
- Sara Taleb
- Sara Ventura
- Sarah E McDonald
- Sarah Isgett
- Sarah Moore
- Sarah Redl
- Sarah Stabler
- Sarah Syahrin
- Sarah Tubiana
- Saye Khoo
- Scott Pharand
- Seamus Daly
- Sean Donohue
- Sebastian Vencken
- Sebastiano Maria Colombo
- Segolène Greffe
- Semple Malcolm G
- Senthilkumar Alegesan
- Sergio Poli
- Seán Keating
- Shahdattul Mawarni Taib
- Shaikh Sharjeel
- Shakeel Ahmed
- Shaminee Veeran
- Sharma Keshav
- Sharma Pratima
- Shaun Thompson
- Shaunagh Browne
- Sheeba Hakak
- Sheila Cárcel
- Sherry McDermott
- Sheryl Ann Abdukahil
- Shinichiro Ohshimo
- Shiranee Sriskandan
- Shirin Tabrizi
- Shirley Sarfo-Mensah
- Shoban Raj Vasudayan
- Shona C Moore
- Shubha Kalyan Shrestha
- Sia Loong Tonnii
- Sigfrid Louise
- Silvia Castañeda
- Silvia Lourenco
- Sim Choon Ean
- Sim Lim Heng Benedict
- Simon Bessis
- Simon Forsyth
- Simon-Djamel Thiberville
- Simone Carelli
- Simão Rodeia
- Singh Oinam Budha Charan
- Siobhan Casey
- Siobhan Egan
- Siri Goepel
- Siti Nurul Atikah Ahmad Ridzuan
- Siti Rohani Binti Mohd Yakop
- Siti Zubaidah Othman
- Sivanesen Anthonidass
- Smaragdi Kalomoiri
- Sobia Masood
- Sofia Cardoso
- Sofia Prapa
- Sofia Tejada
- Sofía Contreras
- Soizic Le Mestre
- Somers Emily C
- Sophie Halpin
- Sophie Mahy
- Sophie O'Halloran
- Sravya Pudota
- Sree Satyapriya
- Srinivas Murthy
- Stanislas Rebaudet
- Steffi Ryckaert
- Stella Huo
- Stella Rousset
- Stephan Schroll
- Stephanie Nonas
- Stephanie Roberts
- Stephanie Yerkovich
- Stephanie-Susanne Stecher
- Stephen R Knight
- Steve Webb
- Stijn Van de Velde
- Streinu-Cercel Anca
- Stuart Houltham
- Stéphane Jaureguiberry
- Stéphane Lasry
- Stéphane Sallaberry
- Stéphanie Cousse
- Stéphanie Fry
- Su Hwan Lee
- Subbarao Elapavaluru
- Subhash Acharya
- Sudhir Krishnan
- Sue Smith
- Suhaila Abdul Wahab
- Sung-Min Cho
- Surain Raaj Thanga Thurai
- Suresh Kumar Chidambaram
- Surya Otto Wijaya
- Susana Cabral
- Susana Fernandes
- Susanne Dudman
- Sushil Khanal
- Suvintheran Thangavelu
- Suwarti Suwarti
- Suzanne Bennett
- Suzette Willems
- Swosti Joshi
- Syamin Asyraf Shahidan
- Sybille Bevilcaqua
- Syed Muneeb
- Sylvain Diamantis
- Sylvie Behilill
- Sylvie LeGac
- Sylvie Lion-Daolio
- Sylvie Van Der Werf
- Synne Jenum
- Sze Kye Teoh
- Sébastien Preau
- Sérgio Gaião
- Séverine Ansart
- Sílvia Ferreira
- T Eoin West
- Taccone Fabio
- Tae Song
- Taha Pasha
- Tahira Jamal Mohamed
- Tak-Hyuk Oh
- Takako Akimoto
- Takayuki Ogura
- Taku Tanaka
- Tala Al-Dabbous
- Tamara Seitz
- Tan Pei Wen
- Tarek Elshazly
- Tatiana Fonseca
- Tawnya Ogston
- Teck Fung Wong
- Teresa Lawrence
- Terese Hammond
- Thalha Rashan
- Tharmini Ravi
- Tharwat Aisa
- Thavamany Kaleesvran
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomas Staudinger
- Thushan de Silva
- Théo Treoux
- Tiago Isidoro
- Tiago Reyes
- Tiffany Trouillon
- Timo Brandenburger
- Timothy M Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Tjard Schermer
- Todd C Lee
- Todd Karsies
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Tomoyuki Endo
- Toni Duculan
- Tony Trapani
- Toshiki Yokoyama
- Triona Downer
- Tristan Gigante
- Trude Steinsvik
- Tze Vee Soh
- Tze Yuan Tee
- Tânia Sequeira
- Vadim Tieroshyn
- Valentine Campana
- Valeria Balan
- Valla Sahraei
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Vanessa Sancho-Shimizu
- Vanessa Teotonio
- Vanina Meysonnier
- Vecham Pavan Kumar
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Vicente Souza-Dantas
- Victor Fomin
- Victoria Janes
- Victoria Manda
- Victoria McEneany
- Victoria Shaw
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Véronique Lemee
- Víctor Quirós González
- Wai Ching Sin
- Walter Picard
- Wan Fadzlina Wan Muhd Shukeri
- Wei Han Hoh
- Wei Shen Lim
- Wei Jia
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Finlayson
- William Greenhalf
- Wilna Oosthuyzen
- Wils Evert-Jan
- Wim Dieperink
- Wing Yiu Ng
- Xavier Duval
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zul Amali Che Kamaruddin
- Zul Fakar
- Zulfiqar Sandhu
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 28/02/2023
- Field of study
Background: We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized data sets concerning hospitalized patients. Methods: The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admission to an intensive care unit (ICU) and invasive mechanical ventilation (IMV). Results: Data were available for 689 572 patients with laboratory-confirmed (91.1%) or clinically diagnosed (8.9%) SARS-CoV-2 infection from 52 countries. Age [adjusted hazard ratio per 10 years 1.49 (95% CI 1.48, 1.49)] and male sex [1.23 (1.21, 1.24)] were associated with a higher risk of death. Rates of admission to an ICU and use of IMV increased with age up to age 60 years then dropped. Symptoms, co-morbidities and treatments varied by age and had varied associations with clinical outcomes. The case-fatality ratio varied by country partly due to differences in the clinical characteristics of recruited patients and was on average 21.5%. Conclusions: Age was the strongest determinant of risk of death, with a ∼30-fold difference between the oldest and youngest groups; each of the co-morbidities included was associated with up to an almost 2-fold increase in risk. Smoking and obesity were also associated with a higher risk of death. The size of our international database and the standardized data collection method make this study a comprehensive international description of COVID-19 clinical features. Our findings may inform strategies that involve prioritization of patients hospitalized with COVID-19 who have a higher risk of death