What's in a name? Brand name confusion and generic medicines

We need an urgent review of medicines labelling in Australia and New Zealand.Shane L Carney, Madlen Gazarian, Justin T Denholm, David M Reith, Robert K Penhall, Christine R Jenkins, Kay A Wilhelm, Paul A Komesaroff, Mary M Osborn and Richard O Da

Paleotectonics of a complex Miocene half graben formed above a detachment fault: The Diligencia basin, Orocopia Mountains, southern California

The Diligencia basin in the Orocopia Mountains of southeastern California has been one of the primary areas used to test the hypothesis of more than 300 km of dextral slip along the combined San Andreas/San Gabriel fault system. The Orocopia Mountains have also been the focus of research on deposition, deformation, metamorphism, uplift and exposure of the Orocopia Schist, which resulted from fl at-slab subduction during the latest Cretaceous/Paleogene Laramide orogeny. The uppermost Oligocene/Lower Miocene Diligencia Formation consists of more than 1500 m of nonmarine strata, including basalt fl ows and intrusions dated at 24-21 Ma. The base of the Diligencia Formation sits nonconformably on Proterozoic augen gneiss and related units along the southern basin boundary, where low-gradient alluvial fans extended into playa-lacustrine environments to the northeast. The northern basal conglomerate of the Diligencia Formation, which was derived from granitic rocks in the Hayfield Mountains to the north, sits unconformably on the Eocene Maniobra Formation. The northern basal conglomerate is overlain by more than 300 m of mostly red sandstone, conglomerate, mudrock and tuff. The basal conglomerate thins and fines westward; paleocurrent measurements suggest deposition on alluvial fans derived from the northeast, an interpretation consistent with a NW-SE-trending normal fault (present orientation) as the controlling structure of the half graben formed during early Diligencia deposition. This fault is hereby named the Diligencia fault, and is interpreted as a SW-dipping normal fault, antithetic to the Orocopia Mountains detachment and related faults. Deposition of the upper Diligencia Formation was infl uenced by a NE-dipping normal fault, synthetic with, and closer to, the exposed detachment faults. The Diligencia Formation is nonconformable on Mesozoic granitoids in the northwest part of the basin. Palinspastic restoration of the Orocopia Mountain area includes the following phases, each of which corresponds with microplate-capture events along the southern California continental margin: (1) Reversal of 240 km of dextral slip on the San Andreas fault (including the Punchbowl and other fault strands) in order to align the San Francisquito-Fenner-Orocopia Mountains detachment-fault system at 6 Ma. (2) Reversal of N-S shortening and 90° of clockwise rotation of the Diligencia basin and Orocopia Mountains, and 40 km of dextral slip on the San Gabriel fault between 12 and 6 Ma. (3) Reversal of 40° of clockwise rotation of the San Gabriel block (including Soledad basin and Sierra Pelona) and 30 km of dextral slip on the Canton fault between 18 and 12 Ma. These palinspastic restorations result in a coherent set of SW-NE-trending normal faults, basins (including Diligenica basin) and antiformal structures consistent with NW-SE-directed crustal extension from 24 to 18 Ma, likely resulting from the unstable configuration of the Mendocino triple junction

Quality and nutritional property changes in stored dried apricots fumigated by sulfur dioxide

WOS: 000354216000010Apricots are grown in many countries and are marketed as dried or fresh. Sulfur fumigation is preferred as a low-cost pre-treatment to maintain apricot color. This study aims to determine the effect of sulfur dioxide (SO2) concentration on quality and nutritional properties of dried apricot fruits during storage. Apricot fruits were treated with different concentrations of SO2 (1,250, 2,000, and 3,500 mg center dot kg(-1)) and then stored at 20A degrees C under 50-65% relative humidity conditions for 18 months. Fruit SO2 concentration decreased rapidly during the initial stage and then decreased at a slower rate. Fruit color darkening became more pronounced after 12 months, especially in the fruit treated with 1,250 and 2,000 mg center dot kg(-1) SO2. After 18 months of storage, total phenolic content (839-890 mg GAE 100 g(-1) dry weight), antioxidant activity (9.4-11.6 mu mol TE g(-1) dry weight), and beta-carotene levels (42.7-47.6 mg center dot kg(-1)) of all treatments varied only slightly, despite lower values overall. Therefore, SO2 levels must be chosen based on the expected storage conditions and length of the storage period.Aegean Exporters' AssociationsEge UniversityThis research is funded by the Aegean Exporters' Associations

Bioleaching of a low-grade copper ore: Linking leach chemistry and microbiology

Three largely-independent studies were undertaken on the same heap leach system during the period of transition from processing oxidised ores to sulfide ores: monitoring of heap solutions for microorganisms, analysis of samples from a spent heap, and column tests. Microbial cell numbers and diversity were monitored in process water samples from the transition heap over a four-year period. Cell numbers remained low throughout, 1–30 × 104 cells mL−1, possibly reflecting growth inhibition by the high element concentrations in process water. High iron, magnesium and aluminium concentrations in spent heap pregnant leach solution (PLS) are attributed to siderite and clinochlore dissolution and would be expected to impact on microbial growth. Planktonic cell numbers in a column leachate declined rapidly by two orders of magnitude when concentrations of ferric ion and sulfate exceeded 30 and 75 g L−1, respectively. Nevertheless, a variety of bacterial strains closely related to Acidithiobacillus (At.) ferrooxidans, At. caldus, Leptospirillum (L.) ferriphilum, Acidimicrobium (Am.) ferrooxidans, Acidiphilium (Ap.) cryptum, an Alicyclobacillus-related strain and Sulfobacillus (S.) thermosulfidooxidans, and the archaeon Ferroplasma (F.) acidiphilum were isolated, mainly from the more acidic intermediate leach solutions (ILS).Overall, the results obtained from the use of culture-dependent and culture-independent methods of community analysis were complementary and consistent. The majority of identified genera and species were present in both the process water samples from the operating heap and the solutions and ore samples from the spent heap. In the spent heap, distinct populations dominated different sample types. Leptospirillum- and Acidithiobacillus-like strains dominated PLS samples and Leptospirillum also dominated seven of eight spent ore samples and all of the heap sediment samples, making it the primary iron(II) oxidising species