1,200 research outputs found

    Verteilung und Leitung der Personalaffixe im Ungarischen

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    Anders als in den indogermanischen Sprachen kann im Ungarischen nicht nur das finite Verb Personalkennzeichen tragen, sondern auch der Infinitiv, bestimmte Partizipformen, Nomina, Pronomina und einige weitere Wortbildungen. Nach der mir zur Verfügung stehenden Literatur ist bisher nicht oder nur indirekt versucht worden, das Spektrum dieser, immer suffixalen Personalmarkierung in einer Zusammenschau zu erfassen und auf seine Funktion hin zu untersuchen. So findet sich in Grammatiken und Handbüchern des Ungarischen häufig nur die allgemeine Unterscheidung von verbalen und 'possessiven' Personalendungen – eine Sicht, die allein auf der formalen Seite dieser Suffixe beruht und terminologisch eine unzulässige Verkürzung darstellt. Wie TOMPA (1968:178) richtig vermerkt, müssen die nichtverbalen Personalzeichen unter Berücksichtigung ihrer spezifischen Funktion differenziert werden. [...] Diese Arbeit wird noch einen Schritt weitergehen und jede einzelne Kombinationsmöglichkeit einer bestimmten Stammkategorie mit Personalsuffixen getrennt behandeln, wobei kein Anspruch auf Vollständigkeit erhoben werden kann. Das Ziel der Arbeit ist ein zweifaches: Zum einen geht es um eine Bestandsaufnahme der wichtigsten Verwendungen der Personalendungen und der mit ihnen gebildeten Konstruktionen ("Verteilung der Personalaffixe"), zum anderen um eine funktionale und auch formale Analyse dieses affixalen Personalausdrucks ("Leistung der Personalaffixe"). Die Arbeit gliedert sich in drei Teile: Nach einer allgemeinen Einführung in einige morphologische und phonologische Charakteristika des Ungarischen (Kap. l) gibt der umfangreichste Teil der Arbeit einen Überblick über die Bildung und Verwendung personalsuffigierter Kategorien (Kap. 2). An diese Bestandsaufnahme schließt sich eine Analyse der Leistung (und auch der Form) des affixalen Personalausdrucks an (Kap. 3.) und ein kurzes Fazit der beobachteten Phänomene (Kap. 4)

    An Approach for the Transfer of Real Surfaces in Finite Element Simulations

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    Virtual simulations are a relevant element in product engineering processes and facilitate engineers to test different concepts during early phases of the development. However, in tribological product engineering, simulations are hardly used because input data such as material behavior are often missing. Besides the material behavior, the surface roughness of the contacting elements is relevant for tribological systems. To expand the capabilities of the virtual engineering of tribological components such as bearings or brakes, the hereby presented approach allows for the depiction of real rough surfaces in finite element simulations. Rough surfaces are scanned by a white-light interferometer (WLI) and further processed by removing the outliers and replacing non-measured samples. Next, a spline generation creates a solid body, which is imported to CAD software and afterwards meshed with triangle and quadrilateral elements in different sizes. The results comprise the evaluation of six differently manufactured (turned, coated, and pressed) real surfaces. The surfaces are compared by the deviations of the roughness values after measuring with the WLI and after meshing them. Furthermore, the elements’ aspect ratios and skewness describe the mesh quality. The results show that the transfer is dependent upon deep cliffs and large Sz values in comparison to the lateral expansion

    Interdisciplinary approach for the treatment of periodontally compromised malpositioned anterior teeth: a case report

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    Today many adult patients with periodontal disease demonstrate positioning of teeth that comprise their ability for proper mechanical tooth cleaning of approximal tooth surfaces. With adequate combined periodontal-orthodontic treatment it is possible to re-establish a healthy and well-functioning dentition. However, while orthodontic treatment can realign periodontally affected teeth, esthetic appearance may be compromised by gingival recession due to alveolar bone dehiscences or fenestrations in combination with a thin gingival biotype. This article reports an interdisciplinary (periodontic, orthodontic, restorative) approach for the treatment of a periodontally compromised patient with anterior dental malalignment. Periodontal therapy, including periodontal plastic surgery to obtain root coverage as well as orthodontic treatment by means of a miniscrew implant anchorage were used to achieve stable periodontal conditions and successful esthetic and functional final results

    IMPETUS: Implementing HELP in the Upper Ouémé basin

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    Regional climate models that take into account land-use changes indicate that in the future, a general decrease in rainfall, together with prominent surface heating, can be expected for sub-Saharan Africa and the region north of the Sahara until 2050. Due to high population growth, land use changes rapidly and influences water availability and water demand. In this context, the research project IMPETUS (‘An Integrated Approach to the Efficient Management of Scarce Water Resources in West Africa’) offers a range of options for sustainable management of different components of the hydrological cycle. Target areas are the Ouémé basin in Benin and the Drâa catchment in Morocco. This paper concentrates on the Ouémé basin.Based on plausible scenarios of future economic, demographic, and climate developments, the effects of land use, land cover change, climate change, and demographic development on water availability and water demand are quantified. Scenarios of future water availability and water demand for the Upper Ouémé (Benin) catchment are discussed. To calculate water availability, the output of a regional climate model was linked to a hydrological model that also considered land use change calculated by a cellular automata model. Future water requirements were computed by linking population growth and per capita water demand, which was derived from a regional survey. Furthermore, the need for water for animal husbandry was considered.The results of the ‘business as usual’ scenario, combined with IPCC Scenarios A1B and B2, through the year 2045 are presented. The results reveal a significant decrease in water availability (surface water and groundwater) due to a decrease in rainfall and a significant increase in evapotranspiration. Although total water consumption increases strongly, it represents only about 0.5% of the yearly renewable water resources. Comparing these data, it may be concluded that water scarcity is not a problem in Benin. However, water availability shows high temporal variations due to the rainy and the dry seasons. Even if physical water scarcity is not a limiting factor, access to water in some parts of the catchment is limited due to economic factors.Keywords: HELP, IMPETUS, Benin, Morocco, Decision Support Systems, global change, information systems, loosely coupled models, problem clusters, scenario development, water availability, water deman

    Online Tracking of the Contents of Conscious Perception Using Real-Time fMRI

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    Perception is an active process that interprets and structures the stimulus input based on assumptions about its possible causes. We use real-time functional magnetic resonance imaging (rtfMRI) to investigate a particularly powerful demonstration of dynamic object integration in which the same physical stimulus intermittently elicits categorically different conscious object percepts. In this study, we simulated an outline object that is moving behind a narrow slit. With such displays, the physically identical stimulus can elicit categorically different percepts that either correspond closely to the physical stimulus (vertically moving line segments) or represent a hypothesis about the underlying cause of the physical stimulus (a horizontally moving object that is partly occluded). In the latter case, the brain must construct an object from the input sequence. Combining rtfMRI with machine learning techniques we show that it is possible to determine online the momentary state of a subject’s conscious percept from time resolved BOLD-activity. In addition, we found that feedback about the currently decoded percept increased the decoding rates compared to prior fMRI recordings of the same stimulus without feedback presentation. The analysis of the trained classifier revealed a brain network that discriminates contents of conscious perception with antagonistic interactions between early sensory areas that represent physical stimulus properties and higher-tier brain areas. During integrated object percepts, brain activity decreases in early sensory areas and increases in higher-tier areas. We conclude that it is possible to use BOLD responses to reliably track the contents of conscious visual perception with a relatively high temporal resolution. We suggest that our approach can also be used to investigate the neural basis of auditory object formation and discuss the results in the context of predictive coding theory

    The Social Value of Health Insurance: Results from Ghana

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    We use the roll-out of the national health insurance in Ghana to assess the cushioning effect of coverage on the financial consequences of health shocks and resulting changes in coping behaviors. We find a strong reduction in medical expenditures, preventing households from cutting non-food consumption and causing a decrease in the volume of received remittances as well as labor supply of healthy adult household members. Moreover, we present evidence that the insurance scheme reduced the likelihood that households experiencing a health shock pulled their children out of school in order to put them to work. Avoidance of such costly coping mechanisms is potentially an important part of the social value of formal health insurance

    A preliminary study in osteoinduction by a nano-crystalline hydroxyapatite in the mini pig.

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    To test the probable osteoinductive properties of NanoBone, a new highly non-sintered porous nano-crystalline hydroxylapatite bone substitute embedded into a silica gel matrix, granules were implanted subcutaneously and intramuscularly into the back region of 18 mini pigs. After periods of 5 and 10 weeks as well as 4 and 8 months, implantation sites were investigated using histological and histomorphometric procedures. Signs of early osteogenesis could already be detected after 5 weeks. The later periods were characterized by increasing membranous osteogenesis in and around the granules leading to the formation of bone-like structures showing periosteal and tendon-like structures with bone marrow and focal chondrogenesis. Bone formation was better in the subcutaneous than in the intramuscular implantation sites. This ectopic osteogenesis is discussed with regard to the nanoporosity and microporosity of the material, physico-chemical interactions at its surface, the differentiation of osteoblasts, the role of angiogenesis and the probable involvement of growth factors. The results of this preliminary study indicate that this biomaterial has osteoinductive potential and induces the formation of bone structures, mainly in subcutaneous adipose tissue in the pig

    Initial response to the COVID-19 pandemic on real-life well-being, social contact and roaming behavior in patients with schizophrenia, major depression and healthy controls: A longitudinal ecological momentary assessment study

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    The COVID-19 pandemic strongly impacted people\u27s daily lives. However, it remains unknown how the pandemic situation affects daily-life experiences of individuals with preexisting severe mental illnesses (SMI). In this real-life longitudinal study, the acute onset of the COVID-19 pandemic in Germany did not cause the already low everyday well-being of patients with schizophrenia (SZ) or major depression (MDD) to decrease further. On the contrary, healthy participants’ well-being, anxiety, social isolation, and mobility worsened, especially in healthy individuals at risk for mental disorder, but remained above the levels seen in patients. Despite being stressful for healthy individuals at risk for mental disorder, the COVID-19 pandemic had little additional influence on daily-life well-being in psychiatric patients with SMI. This highlights the need for preventive action and targeted support of this vulnerable population

    Low‐voltage shock impedance measurements: A false sense of security

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    Background: Implantable cardioverter defibrillators use low-voltage shock impedance measurements to monitor the lead integrity. However, previous case reports suggest that low-voltage shock impedance measurements may fail to detect insulation breaches that can cause life-threatening electrical short circuits. Methods and results: We report six cases of insulation breaches in transvenous defibrillation leads that were not obvious during standard interrogations and testing of the lead beforehand. In two cases, an electrical short circuit during commanded shock delivery for internal electrical cardioversion resulted in a total damage of the ICD generator. In one of these cases, commanded shock delivery induced ventricular fibrillation, which required external defibrillation. In two cases, a shock due to ventricular tachycardia was aborted as the shock impedance was less than 20 Ω. However, in both cases the tiny residual shock energy terminated the ventricular tachycardia. In contrast, in one case the residual energy of the aborted shock did not end ventricular fibrillation induced at defibrillator threshold testing. In one case, the ICD indicated an error code for a short circuit condition detected during an adequate shock delivery. Conclusions: This case series illustrates that low-voltage shock impedance measurements can fail to detect insulation breaches. These data suggest that in patients without a contraindication, traditional defibrillator threshold testing or high voltage synchronized shock at the time of device replacement should be considered

    Modulation of Osteogenic Cell Morphology by ECM Ligands and Enamel Matrix Derivative

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    Preduvjet za uspješnu regeneraciju parodontnog tkiva jest odgovarajuća aktivacija populacije za to odgovornih stanica, poput osteoblasta. U tom su slučaju stanična adhezija i sazrijevanje usko povezani s morfologijom stanica i f-aktinskom organizacijom citoskeleta. Mogućnost pojačavanja parodontalnog cijeljenja pomoću pojedinih komponenti izvanstaničnog matriksa (ECM) i derivata caklinskog matriksa dobro je dokumentirana u literaturi. Svrha rada: Svrha ovog istraživanja bila je testirati učinak ECM-bjelančevina, kolagena tipa I, laminina-1 te komercijalnog proizvoda EMD-a na morfološku i citoskeletnu organizaciju osteogenih stanica. Ispitanici i postupci: Tijekom promatranja analizirano je ukupno 2450 osteogenih stanica iz pet različitih staničnih linija (četiri primarnih i jedne komercijalne) kultiviranih na pojedinim supstratima, a analizirali su ih tri neovisna promatrača. Nakon bojenja za f-aktin staničnog citoskeleta i automatizirane CLSM-vizualizacije, stanice su podijeljene u tri skupine ovisno o njihovim morfološkim svojstvima (nezrele, prijelazne i zrele). Osim deskriptivne analize obavljena je bila i multivarijantna logička regresija radi identificiranja odgovarajućih parametara koji utječu na staničnu morfologiju i organizaciju citoskeleta. Rabljeni pojedinačni ligandi kolagena i laminina te posebice EMD poticali su stvaranje zrelog osteogenog fenotipa, premda su bile uočene i određene razlike među korištenim staničnim linijama. Rezultati: Analiza morfologije i citoskeleta pouzdan je način skupljanja prvih podataka o biokompatibilnosti i bioaktivaciji stanica na različitim supstratima. Naši rezultati upućuju na mogući potencijal istraživanih liganada u pojačavanju osteogenoga staničnog pričvrstka i sazrijevanju te time i pomaganju cijeljenja parodontnog tkiva.The precondition for successful periodontal regeneration is adequate activation of relevant cell populations like osteogenic cells. Here, cell adhesion and maturation are closely associated with cell morphology and f-actin cytoskeletal organisation. The potential of solitaire extracellular matrix (ECM) components as well as enamel matrix derivative (EMD) to enhance periodontal healing is well documented. Objective: The aim of the study was to test the impact of the ECM proteins collagen type 1 and laminin-1 as well as commercially available EMD on osteogenic cell morphology and cytoskeletal organisation. Material and methods: In an observational study, a total of 2450 osteogenic cells of 5 different cell lines (4 primary ones and 1 commercial one) cultivated on the respective substrates were analysed by 3 independent observers. After staining for the f-actin cytoskeleton and automated CLSM visualisation, cells were assigned to 3 different categories depending on morphological cell attributes (immature vs. intermediate vs. mature). Besides descriptive analysis, a multivariate logistic regression was performed to identify relevant influence parameters on cell morphology and cytoskeletal organisation. Results: The applied solitaire ligands collagen and laminin and especially EMD promoted a mature osteogenic phenotype. Nevertheless, considerable differences between the investigated cell lines could be identified as well. Analysis of cell morphology and cytoskeletal organisation offers a reliable method of acquiring the first hints of biocompatibility and bio-activation on different substrates. Conclusion: Our results highlight the potential of the investigated ligands to support periodontal regeneration by enhancing osteogenic cell attachment and maturation
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