Diffuse swelling of the buccal mucosa and palate as first and only manifestation of an extranodal non-Hodgkin ‘double-hit' lymphoma: report of a case

Background: Most of the lymphomas arising in the oral cavity are of B-cell origin. Among these, diffuse large B-cell lymphomas are the most common. Diffuse large B-cell lymphomas may exhibit more than one chromosomal rearrangement and are then referred to as ‘double-hit' or ‘triple-hit' lymphomas. Case report: We present a case of an intraoral ‘double-hit' lymphoma in a 76-year-old male who had been referred by an oral surgeon in private practice. Intraoral examination exhibited a firm, exophytic lesion in the region of the right hard palate and buccal mucosa with extension to the soft palate. Radiographic examination exhibited a massive thickening of the right sinus membrane, and arrosion of the lateral and basal cortical sinus walls in the right maxilla. After diagnosis of the lesion, the patient was treated with six cycles of chemotherapy. Discussion: Lymphomas arising within the oral cavity account for less than 5% of all oral malignancies and typically affect the palatine tonsils and the palate. ‘Double-hit' lymphomas are associated with older age, usually present with an advanced stage of disease, and show an aggressive clinical behaviour. They normally have a poor prognosis, even when treated with intensive chemotherapy regimens. Nevertheless, in the case presented, the patient was free of symptoms 1year after initial diagnosi

Science results from the imaging Fourier transform spectrometer SpIOMM

SpIOMM is an imaging Fourier transform spectrometer designed to obtain the visible range (350 to 850 nm) spectrum of every light source in a circular field of view of 12 arcminutes in diameter. It is attached to the 1.6-m telescope of the Observatoire du Mont Megantic in southern Quebec. We present here some results of three successful observing runs in 2007, which highlight SpIOMMs capabilities to map emission line objects over a very wide field of view and a broad spectral range. In particular, we discuss data cubes from the planetary nebula M27, the supernova remnants NGC 6992 and M1, the barred spiral galaxy NGC7479, as well as Stephans quintet, an interacting group of galaxies.Comment: 10 pages, 7 figures, to appear in "Ground-based and Airborne Instrumentation for Astronomy II", SPIE conference, Marseille, 23-28 June 200

Apophis planetary defense campaign

We describe results of a planetary defense exercise conducted during the close approach to Earth by the near-Earth asteroid (99942) Apophis during 2020 December–2021 March. The planetary defense community has been conducting observational campaigns since 2017 to test the operational readiness of the global planetary defense capabilities. These community-led global exercises were carried out with the support of NASA's Planetary Defense Coordination Office and the International Asteroid Warning Network. The Apophis campaign is the third in our series of planetary defense exercises. The goal of this campaign was to recover, track, and characterize Apophis as a potential impactor to exercise the planetary defense system including observations, hypothetical risk assessment and risk prediction, and hazard communication. Based on the campaign results, we present lessons learned about our ability to observe and model a potential impactor. Data products derived from astrometric observations were available for inclusion in our risk assessment model almost immediately, allowing real-time updates to the impact probability calculation and possible impact locations. An early NEOWISE diameter measurement provided a significant improvement in the uncertainty on the range of hypothetical impact outcomes. The availability of different characterization methods such as photometry, spectroscopy, and radar provided robustness to our ability to assess the potential impact risk

Proposing a model for the holistic use of sustainability initiatives – a multiple case study

Purpose: The purpose of this research is to investigate how companies address sustainability holistically and compare the practical results to theoretical findings. The holistic approach of sustainability includes four dimensions and five corporate system elements.   Methods: For creating the theoretical framework a literature review was executed. Empirical data was gathered from a multiple case study. In total five case companies have been selected and five interviews have been conducted. Furthermore the interview guideline included a small survey. Empirical data was complemented by information from sustainability reports and companies website.   Main findings: Sustainability is partly executed in differently in practical terms compared to theory research. The differences are mainly explained by the unique use of sustainability initiatives, which are adapted to companies circumstances.   Academic contributions: Previously, only a few researchers investigated the combination of initiatives to provide a holistic sustainability approach. Furthermore a lack of practical research in the field of sustainability has been identified. This thesis contributes to close this gap by investigating five case companies regarding the use of multiple initiatives.   Practical implications: Based on the findings a model was created by the authors. By applying this model and using recommended initiatives companies are able to establish a holistic sustainability approach, involving all sustainability dimensions and corporate system elements.   Limitations: The interviews have been translated from German or Dutch into English, which increases the risk of wrong interpretations. Further the interview involved only one representative per company. Additionally the number of small case study companies and case companies from the service sector might limit the generalization of the results

Proposing a model for the holistic use of sustainability initiatives – a multiple case study

Purpose: The purpose of this research is to investigate how companies address sustainability holistically and compare the practical results to theoretical findings. The holistic approach of sustainability includes four dimensions and five corporate system elements.   Methods: For creating the theoretical framework a literature review was executed. Empirical data was gathered from a multiple case study. In total five case companies have been selected and five interviews have been conducted. Furthermore the interview guideline included a small survey. Empirical data was complemented by information from sustainability reports and companies website.   Main findings: Sustainability is partly executed in differently in practical terms compared to theory research. The differences are mainly explained by the unique use of sustainability initiatives, which are adapted to companies circumstances.   Academic contributions: Previously, only a few researchers investigated the combination of initiatives to provide a holistic sustainability approach. Furthermore a lack of practical research in the field of sustainability has been identified. This thesis contributes to close this gap by investigating five case companies regarding the use of multiple initiatives.   Practical implications: Based on the findings a model was created by the authors. By applying this model and using recommended initiatives companies are able to establish a holistic sustainability approach, involving all sustainability dimensions and corporate system elements.   Limitations: The interviews have been translated from German or Dutch into English, which increases the risk of wrong interpretations. Further the interview involved only one representative per company. Additionally the number of small case study companies and case companies from the service sector might limit the generalization of the results

Hydrogen concentration analysis in clinopyroxene using proton-proton scattering analysis

Traditional methods to measure water in nominally anhydrous minerals (NAMs) are, for example, Fourier transformed infrared (FTIR) spectroscopy or secondary ion mass spectrometry (SIMS). Both well-established methods provide a low detection limit as well as high spatial resolution yet may require elaborate sample orientation or destructive sample preparation. Here we analyze the water content in erupted volcanic clinopyroxene phenocrysts by proton-proton scattering and reproduce water contents measured by FTIR spectroscopy. We show that this technique provides significant advantages over other methods as it can provide a three-dimensional distribution of hydrogen within a crystal, making the identification of potential inclusions possible as well as elimination of surface contamination. The sample analysis is also independent of crystal structure and orientation and independent of matrix effects other than sample density. The results are used to validate the accuracy of wavenumber-dependent vs. mineral-specific molar absorption coefficients in FTIR spectroscopy. In addition, we present a new method for the sample preparation of very thin crystals suitable for proton-proton scattering analysis using relatively low accelerator potentials

Metastudie industrieller Energieflexibilität: Ein Ansatz zur optimierten Identifikation energetischer Flexibilitätspotenziale

Previous studies on the energetic flexibility of German industry show potentials with a large spread. Therefore, in this article, a systematic analysis of the individual studies and an evaluation of the indicated flexibility potentials are carried out. Based on the existing methods, a bottom-up approach for collecting the data in the production system and the aggregation up to the industry level is presented

Diffuse swelling of the buccal mucosa and palate as first and only manifestation of an extranodal non-Hodgkin 'double-hit' lymphoma: report of a case

Most of the lymphomas arising in the oral cavity are of B-cell origin. Among these, diffuse large B-cell lymphomas are the most common. Diffuse large B-cell lymphomas may exhibit more than one chromosomal rearrangement and are then referred to as 'double-hit' or 'triple-hit' lymphomas