217 research outputs found
The simulation of ionospheric conditions for space vehicles
Plasma wind tunnel to simulate ionospheric conditions for space vehicle
Modeling and Analysis of Power Processing Systems
The feasibility of formulating a methodology for the modeling and analysis of aerospace electrical power processing systems is investigated. It is shown that a digital computer may be used in an interactive mode for the design, modeling, analysis, and comparison of power processing systems
Multi-kilowatt modularized spacecraft power processing system development
A review of existing information pertaining to spacecraft power processing systems and equipment was accomplished with a view towards applicability to the modularization of multi-kilowatt power processors. Power requirements for future spacecraft were determined from the NASA mission model-shuttle systems payload data study which provided the limits for modular power equipment capabilities. Three power processing systems were compared to evaluation criteria to select the system best suited for modularity. The shunt regulated direct energy transfer system was selected by this analysis for a conceptual design effort which produced equipment specifications, schematics, envelope drawings, and power module configurations
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Remediation and Recycling of Linde FUSRAP Materials
During World War II, the Manhattan Engineering District (MED) utilized facilities in the Buffalo, New York area to extract natural uranium from uranium-bearing ores. The Linde property is one of several properties within the Tonawanda, New York Formerly Utilized Sites Remedial Action Program (FUSRAP) site, which includes Linde, Ashland 1, Ashland 2, and Seaway. Union Carbide Corporation's Linde Division was placed under contract with the Manhattan Engineering District (MED) from 1942 to 1946 to extract uranium from seven different ore sources: four African pitchblende ores and three domestic ores. Over the years, erosion and weathering have spread contamination from the residuals handled and disposed of at Linde to adjacent soils. The U.S. Department of Energy (DOE) and the U.S. Environmental Protection Agency (EPA) negotiated a Federal Facilities Agreement (FFA) governing remediation of the Linde property. In Fiscal Year (FY) 1998, Congress transferred cleanup management responsibility for the sites in the FUSRAP program, including the Linde Site, from the DOE to the U.S. Army Corps of Engineers (USACE), with the charge to commence cleanup promptly. All actions by the USACE at the Linde Site are being conducted subject to the administrative, procedural, and regulatory provisions of the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) and the existing FFA. USACE issued a Proposed Plan for the Linde Property in 1999 and a Final Record of Decision (ROD) in 2000. USACE worked with the local community near the Tonawanda site, and after considering public comment, selected the remedy calling for removing soils that exceed the site-specific cleanup standard, and transporting the contaminated material to off-site locations. The selected remedy is protective of human health and the environment, complies with Federal and State requirements, and meets commitments to the community
Dynamics and Ethics of Comprehensive Preimplantation Genetic Testing. A Review of the Challenges
BACKGROUND: Genetic testing of preimplantation embryos has been used for preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS). Microarray technology is being introduced in both these contexts, and is to be expected that also whole genome sequencing of blastomeres will become possible. The amount of extra information such tests will yield may prove to be beneficial for embryo selection, but also raise various ethical issues. We present an overview of the developments and an agenda-setting exploration of the ethical issues. METHODS: The paper is a joint endeavour by the presenters at an explorative 'campus meeting' organized by the European Society of Human Reproduction and Embryology in cooperation with the department of Health, Ethics & Society of the Maastricht University (The Netherlands). RESULTS: The increasing amount and detail of information that new screening techniques such as microarrays and whole genome sequencing offer does not automatically coincide with an increasing understanding of the prospects of an embryo. From a technical point of view, the future of comprehensive embryo testing may go together with developments in preconception carrier screening. From an ethical point of view, the increasing complexity and amount of information yielded by comprehensive testing techniques will lead to challenges to the principle of reproductive autonomy and the right of the child to an open future, and may imply a possible larger responsibility of the clinician towards the welfare of the future child. “Smart combinations” of preconception carrier testing and embryo testing may solve some of these ethical questions but could introduce others. CONCLUSION: As comprehensive testing techniques are entering the IVF clinic, there is a need for a thorough rethinking of traditional ethical paradigms regarding medically assisted reproduction.This article was written by Dr Ainsley Newson during the time of her employment with the University of Bristol, UK (2006-2012). Self-archived in the Sydney eScholarship Repository with permission of Bristol University, Sept 2014
Energy- and flux-budget (EFB) turbulence closure model for the stably stratified flows. Part I: Steady-state, homogeneous regimes
We propose a new turbulence closure model based on the budget equations for
the key second moments: turbulent kinetic and potential energies: TKE and TPE
(comprising the turbulent total energy: TTE = TKE + TPE) and vertical turbulent
fluxes of momentum and buoyancy (proportional to potential temperature).
Besides the concept of TTE, we take into account the non-gradient correction to
the traditional buoyancy flux formulation. The proposed model grants the
existence of turbulence at any gradient Richardson number, Ri. Instead of its
critical value separating - as usually assumed - the turbulent and the laminar
regimes, it reveals a transition interval, 0.1< Ri <1, which separates two
regimes of essentially different nature but both turbulent: strong turbulence
at Ri<<1; and weak turbulence, capable of transporting momentum but much less
efficient in transporting heat, at Ri>1. Predictions from this model are
consistent with available data from atmospheric and lab experiments, direct
numerical simulation (DNS) and large-eddy simulation (LES).Comment: 40 pages, 6 figures, Boundary-layer Meteorology, resubmitted, revised
versio
Decoupling of superconducting layers in magnetic superconductor RuSr_{2}GdCu_{2}O_{8}
We propose the model for magnetic properties of the magnetic superconductor
RuSrGdCuO, which incorporates the theory of the
superconducting/ferromagnetic multilayers. The transition line , on
which the Josephson coupled superconducting planes are decoupled, i.e. , is calculated as a function of the exchange energy . As the
result of this decoupling a nonmonotonic behavior of magnetic properties, like
the lower critical field , Josephson plasma frequency, etc. is realized
near (or by crossing) the line. The obtained results are used in
analyzing the newly discovered antiferromagnetic ruthenocuprate
RuSrGdCuO with possible weak ferromagnetic order in the RuO
planes.Comment: 12 pages, 3 figs embede
Structural and electrical transport properties of superconducting Au{0.7}In{0.3} films: A random array of superconductor-normal metal-superconductor (SNS) Josephson junctions
The structural and superconducting properties of Au{0.7}In{0.3} films, grown
by interdiffusion of alternating Au and In layers, have been studied. The films
were found to consist of a uniform solid solution of Au{0.9}In{0.1}, with
excess In precipitated in the form of In-rich grains of various Au-In phases
(with distinct atomic compositions), including intermetallic compounds. As the
temperature was lowered, these individual grains became superconducting at a
particular transition temperature (Tc), determined primarily by the atomic
composition of the grain, before a fully superconducting state of zero
resistance was established. From the observed onset Tc, it was inferred that up
to three different superconducting phases could have formed in these
Au{0.7}In{0.3} films, all of which were embedded in a uniform Au{0.9}In{0.1}
matrix. Among these phases, the Tc of a particular one, 0.8 K, is higher than
any previously reported for the Au-In system. The electrical transport
properties were studied down to low temperatures. The transport results were
found to be well correlated with those of the structural studies. The present
work suggests that Au{0.7}In{0.3} can be modeled as a random array of
superconductor-normal metal-superconductor (SNS) Josephson junctions. The
effect of disorder and the nature of the superconducting transition in these
Au{0.7}In{0.3} films are discussed.Comment: 8 text pages, 10 figures in one separate PDF file, submitted to PR
Щодо утворення сімейств атомарних радіальних базисних функцій
Наведено схему побудови сімейств атомарних радіальних базисних функцій, які є нескінченно диференційовними фінітними розв'язками функціонально-диференціальних рівнянь, породжених операторами Лапласа та Гельмгольца.The scheme of building a family of atomic radial basis functions which are infinitely differentiable finite solutions of the functional-differential equations containing the Laplace and Helmholtz operators is introduced
A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains
Cyclic nucleotides (cAMP and cGMP) regulate multiple intracellular processes and are thus of a great general interest for molecular and structural biologists. To study the allosteric mechanism of different cyclic nucleotide binding (CNB) domains, we compared cAMP-bound and cAMP-free structures (PKA, Epac, and two ionic channels) using a new bioinformatics method: local spatial pattern alignment. Our analysis highlights four major conserved structural motifs: 1) the phosphate binding cassette (PBC), which binds the cAMP ribose-phosphate, 2) the “hinge,” a flexible helix, which contacts the PBC, 3) the β2,3 loop, which provides precise positioning of an invariant arginine from the PBC, and 4) a conserved structural element consisting of an N-terminal helix, an eight residue loop and the A-helix (N3A-motif). The PBC and the hinge were included in the previously reported allosteric model, whereas the definition of the β2,3 loop and the N3A-motif as conserved elements is novel. The N3A-motif is found in all cis-regulated CNB domains, and we present a model for an allosteric mechanism in these domains. Catabolite gene activator protein (CAP) represents a trans-regulated CNB domain family: it does not contain the N3A-motif, and its long range allosteric interactions are substantially different from the cis-regulated CNB domains
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