1,372 research outputs found
Relative Robust Portfolio Optimization
Considering mean-variance portfolio problems with uncertain model parameters, we contrast the classical absolute robust optimization approach with the relative robust approach based on a maximum regret function. Although the latter problems are NP-hard in general, we show that tractable inner and outer approximations exist in several cases that are of central interest in asset management
Bertolucci'nin yeni kahramanı Türk:9 Oscar'lı Son İmparator'un yönetmeni, birkaç yıl sonra hayatını çekmeyi düşündüğü Türk'ün adını vermedi
Taha Toros Arşivi, Dosya No: 185/A-Sinema Tarihiİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033
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Understanding and Combating Diabetic Wounds at the Moi Teaching and Referral Hospital in Eldoret, Kenya
This research, in a collaborative effort with the wound care team at the Moi Teaching and
Referral Hospital in Eldoret, Kenya, reviews the literature surrounding diabetes in Kenya,
surveys the patients seeking wound care at the hospital, and proposes interventions to
address the increasing burden of diabetic wounds. Research in this area suggests that the
rising diabetes prevalence rate is a function of the epidemiological transition accompanying
industrialization, which goes hand-in-hand with a cultural transition into a more sedentary
lifestyle and an influx of highly processed food into the diet. The author analyzed a dataset
of 122 wound patients at MTRH to gain relevant insight and a constructed profile of the
types of patients and wounds seen at MTRH. Patients who presented with wounds tended
to have worse social determinants of health, such as living below the poverty line or
experiencing housing and food insecurity. They also experienced notable psychological and
economic burdens as a result of their wounds, such as hopelessness and a loss of
productivity. The research proposes potential interventions based on the literature, the
survey results, and conversations with caregivers at the hospital. Suggested interventions
include preventative measures such as diabetic filament tests and pulse exams, patient
education, and psychological and economic support.Public Healt
Doctor of Philosophy
dissertationEvery year millions of children are born with a birth defect. Birth defects, which can be described as abnormalities of structure or function that is present from birth, are the leading cause of infant death in developed countries and a significant cause of morbidity and economic burden in low- or middle-income countries. This dissertation addresses the genetic basis of distal arthrogryposes (DAs), a subgroup of birth defects that are characterized by contractures of the distal joints of a limb. Based on previous research of our laboratory, we hypothesized that DAs are defects of contractile apparatus in fast twitch skeletal myofibers and tested this hypothesis in four DA syndromes. We found that mutations of the embryonic myosin heavy chain gene cause DA2A and DA2B, whereas a missense mutation of the perinatal myosin heavy chain gene is responsible for DA7. Furthermore, we found mutations in the adult and extraocular myosin heavy chain genes in some DA5 patients. Furthermore, we noticed some patients with similar findings who do not meet the diagnostic criteria of the known DA syndromes. We proposed one of these conditions to be named as DA10, and mapped this condition to the long arm of chromosome 2. We named the other condition as the CATSHL syndrome, which we showed to be caused by a loss-of-function mutation in the fibroblast growth factor receptor 3 gene. The main contribution of this research is to benefit affected individuals and their families, since molecular testing can now be offered to them. In addition, through further studies leading to a better understanding of normal and abnormal development, effective strategies for prevention and treatment of congenital limb malformations can be developed
Book review: Feminist city: claiming space in the man-made world by Leslie Kern
In Feminist City: Claiming Space in the Man-Made World, Leslie Kern delves into the interlocking inequalities and systems of oppression that take concrete shape in cities, using an intersectional feminist approach to explore the gendered aspects of urban space. This is an enjoyable and accessible book that not only contributes to urban feminist geography, but to urban planning and policy more broadly, writes Reha Atakan Cetin
Hydrographic Surveying without a Tide Gauge
Depth in hydrographic surveys is measured from the water surface during the survey operation. However, the water surface of oceans, seas and lakes moves as a result of meteorological, oceanographic and tidal effects. Depth values measured at any time and water level should be reduced to a specific vertical datum in order to be used at a different time and different water level. To accomplish that, the changes in water level must be determined. Traditionally, many different types of tide gauges are used for this purpose. The aim of this study is to establish the connection of depth values to a vertical datum without using a tide gauge. For this purpose, an algorithm based on the GPS carrier phase measurement is introduced here. The result shows that, the height of each point at the sea bottom may be obtained without using a tide gauge via the proposed method. Furthermore, if th is method is performed, important error sources such as heave, surge, and tides, which affect the sounding, can be eliminated
Environmental representation: Bridging the drawings and historiography of Mediterranean vernacular architecture
Architectural drawings, which are projections of spaces on a paper surface, can be categorized according to the projections’ directional and temporal relation with the represented space. A projection becomes a documentation when it departs from an existing spatial organization for recording it on paper. The projection serves the design process when it departs from the present to foresee a spatial proposal in the future. While the former records the present within limited interpretive range, the latter is more constructive. While these two types of projections are known widely, there is another highly interpretive type of projection, the potentials of which, are generally underestimated. As the architectural historian’s tool, this third projection type represents bygone architecture. The task of this drawing, which is one of the least questioned issues of architectural history, is to restore an incomplete image by referring to material and textual sources. This drawing type contributes to the methodology of architectural historiography while conceiving, explaining and representing space.For illustrating this situation, this study analyzes the vernacular settlements and their environmental integration because this selected context reveals the interpretive nature of the third type of projection in a successful way. In this framework, the cut-away axonometric is considered as an appropriate drawing method for uncovering the integrity between architecture and its site or culture and nature. The outcome of this theoretical insight into the prolific relations between drawing and architectural history is coined as “environmental representation.”In history architectural products have been integral components of the environment. Then, the architectural representation of historical buildings through drawings becomes critical since the majority of architectural drawings tend to isolate buildings from their environment. This conventional representation of historical architecture has been the dominant tool of typological analysis. Typology, which is intertwined with plan drawings, categorizes historical buildings according to their spatial, structural and material organizations and disengages the buildings from their socio-cultural and environmental context. If this methodological problem of typology is regarded as a problem of drawing, a new mode of “environmental representation” can be proposed.This study proposes “environmental representation” of architecture through cut-away axonometric. This graphic proposal is based upon the theoretical references of “environmental aesthetics”, which is an interdisciplinary field analyzing the participatory human engagement in environment. “Aesthetics,” as a term, defines this bodily engagement into environment through the use of all human senses. In this theoretical framework this study challenges the assumptions of scientific theory for architectural representation of the “abstracted object” and proposes an alternative method of “environmental representation” on the basis of “aesthetics”. Within this scope, the proposed cut-away axonometric drawings produced by the author is analyzed in order to represent exemplary historical contexts of architecture selected through the vernacular settlements of the Anatolian Mediterranean
The Impact of Social Media Advertisement Awareness on Brand Awareness, Brand Image, Brand Attitude and Brand Loyalty: A Research on University Students
Due to the more effective use of social media tools and the further advancement of the internet, marketing efforts of brands have nowadays become more personal, fun, attractive and social. This study analyzes the impact of social media advertisement awareness on brand awareness, brand image, brand attitude and brand loyalty. Participants of the study consisted of 390 students currently enrolled at Van Yüzüncü Yıl University. The research model and hypothesis built for the purpose of the study were tested with structural equation modelling. Results of the analyses concluded that social media advertisement awareness has an impact on brand awareness, brand awareness has an impact on brand image, brand image has an impact on brand attitude and brand attitude has an impact on brand loyalty
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