1,385 research outputs found

    TEACHERS’ EXPERIENCES IN ENGAGEMENT WITH PARTNERS IN ENVIRONMENTAL AND SUSTAINABILITY EDUCATION

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    This thesis is an assessment of how Canadian teachers and principals engage with organizational, business, corporate, and individual partners to enhance environmental and sustainability education (ESE) practice in K-12 schools. The research of this thesis was drawn from data collected for a national comparative case study by the Sustainability and Education Policy Network (SEPN). This thesis study analyzed interview transcripts, numerical ratings, and survey questions. Conclusions were drawn through the comparison of teacher comments and ratings to current education policy regarding partnerships in their regions. Results suggested the influence of policy or lack of policy on practice in a variety of contexts. Data showed most teachers and principals mentioned a specific partner by name when discussing their ESE teaching, implying that partnering with out of school entities is common practice despite little to no policy guiding partnership activities. Teachers tended to mention more partners by name in rural divisions when compared to teachers in urban settings. Some teachers were ‘super-connectors,’ noting far more partnerships than others. Results suggest that teachers tend to be the primary initiators of ESE school-based partnerships. A wide variety of partners were mentioned, but non-governmental organizations (NGOs) were by far the most prevalent. There was also a great diversity in the activities and outcomes resulting from partnerships, though a common theme was that partnerships allowed for lessons that were experiential and regionally specific. This thesis concludes with suggestions for teachers who desire to work with organizations, and recommendations for policy makers regarding how policy could better facilitate and optimize partnerships in furthering environmental and sustainability education

    Association between diabetes, diabetes treatment and risk of developing endometrial cancer.

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    BackgroundA growing body of evidence suggests that diabetes is a risk factor for endometrial cancer incidence. However, most of these studies used case-control study designs and did not adjust for obesity, an established risk factor for endometrial cancer. In addition, few epidemiological studies have examined the association between diabetes treatment and endometrial cancer risk. The objective of this study was to assess the relationships among diabetes, diabetes treatment and endometrial cancer risk in postmenopausal women participating in the Women's Health Initiative (WHI).MethodsA total of 88 107 postmenopausal women aged 50-79 years who were free of cancer and had no hysterectomy at baseline were followed until date of endometrial cancer diagnosis, death, hysterectomy or loss to follow-up, whichever came first. Endometrial cancers were confirmed by central medical record and pathology report review. Multivariate Cox proportional hazards regression models were used to estimate hazard ratios (HRs) (95% confidence interval (CI)) for diagnosis of diabetes and metformin treatment as risk factors for endometrial cancer.ResultsOver a mean of 11 years of follow-up, 1241 endometrial cancers developed. In the primary analysis that focused on prevalent diabetes at enrolment, compared with women without diabetes, women with self-reported diabetes, and the subset of women with treated diabetes, had significantly higher risk of endometrial cancer without adjusting for BMI (HR=1.44, 95% CI: 1.13-1.85 for diabetes, HR=1.57, 95% CI: 1.19-2.07 for treated diabetes). However after adjusting for BMI, the associations between diabetes, diabetes treatment, diabetes duration and the risk of endometrial cancer became non-significant. Elevated risk was noted when considering combining diabetes diagnosed at baseline and during follow-up as time-dependent exposure (HR=1.31, 95% CI: 1.08-1.59) even after adjusting for BMI. No significant association was observed between metformin use and endometrial cancer risk.ConclusionsOur results suggest that the relationship observed in previous research between diabetes and endometrial cancer incidence may be largely confounded by body weight, although some modest independent elevated risk remains

    Effect of Pt substitution on the electronic structure of AuTe2

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    We report a photoemission and x-ray absorption study on Au1-xPtxTe2 (x = 0 and 0.35) triangular lattice in which superconductivity is induced by Pt substitution for Au. Au 4f and Te 3d core-level spectra of AuTe2 suggests a valence state of Au2+(Te2)2-, which is consistent with its distorted crystal structure with Te-Te dimers and compressed AuTe6 otahedra. On the other hand, valence-band photoemission spectra and pre-edge peaks of Te 3d absorption edge indicate that Au 5d bands are almost fully occupied and that Te 5p holes govern the transport properties and the lattice distortion. The two apparently conflicting pictures can be reconciled by strong Au 5d/Au 6s-Te 5p hybridization. Absence of a core-level energy shift with Pt substitution is inconsistent with the simple rigid band picture for hole doping. The Au 4f core-level spectrum gets slightly narrow with Pt substitution, indicating that the small Au 5d charge modulation in distorted AuTe2 is partially suppressed.Comment: 13 pages, 4 figures, accepted by Physical Review

    Ecdysozoan mitogenomics: evidence for a common origin of the legged invertebrates, the Panarthropoda

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    Ecdysozoa is the recently recognized clade of molting animals that comprises the vast majority of extant animal species and the most important invertebrate model organisms—the fruit fly and the nematode worm. Evolutionary relationships within the ecdysozoans remain, however, unresolved, impairing the correct interpretation of comparative genomic studies. In particular, the affinities of the three Panarthropoda phyla (Arthropoda, Onychophora, and Tardigrada) and the position of Myriapoda within Arthropoda (Mandibulata vs. Myriochelata hypothesis) are among the most contentious issues in animal phylogenetics. To elucidate these relationships, we have determined and analyzed complete or nearly complete mitochondrial genome sequences of two Tardigrada, Hypsibius dujardini and Thulinia sp. (the first genomes to date for this phylum); one Priapulida, Halicryptus spinulosus; and two Onychophora, Peripatoides sp. and Epiperipatus biolleyi; and a partial mitochondrial genome sequence of the Onychophora Euperipatoides kanagrensis. Tardigrada mitochondrial genomes resemble those of the arthropods in term of the gene order and strand asymmetry, whereas Onychophora genomes are characterized by numerous gene order rearrangements and strand asymmetry variations. In addition, Onychophora genomes are extremely enriched in A and T nucleotides, whereas Priapulida and Tardigrada are more balanced. Phylogenetic analyses based on concatenated amino acid coding sequences support a monophyletic origin of the Ecdysozoa and the position of Priapulida as the sister group of a monophyletic Panarthropoda (Tardigrada plus Onychophora plus Arthropoda). The position of Tardigrada is more problematic, most likely because of long branch attraction (LBA). However, experiments designed to reduce LBA suggest that the most likely placement of Tardigrada is as a sister group of Onychophora. The same analyses also recover monophyly of traditionally recognized arthropod lineages such as Arachnida and of the highly debated clade Mandibulata

    Descriptive oceanography during the Frontal Air‐Sea Interaction Experiment: Medium‐ to large‐scale variability

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    Medium‐ and large‐scale oceanographic variability in the Sargasso Sea is examined during the Frontal Air‐Sea Interaction Experiment (FASINEX), focusing primarily on processes that influence the formation of subtropical fronts. From Fall to Spring the mean meridional gradient of meridional Ekman transport in the Subtropical Convergence Zone (STCZ) enhances the meridional sea surface temperature (Ts) gradients between 26° and 32°N. In the presence of this enhanced mean gradient, baroclinic eddies with zonal wavelengths of ≈800 km and periods of ≈200 days exert the dominant influence on the formation of subtropical fronts at medium and large scales. These eddies generate westward propagating Ts anomaly features with the same dominant wavelengths and periods. They are confined between 26° and 32°N and have amplitudes that occasionally exceed ±1°C. Ts fronts tend to be found within bands ≈200 km wide that roughly follow the periphery of these anomaly features. Deformation in the horizontal eddy current field is primarily responsible for the existence of these frontal bands. The migration of the strong front originally bracketed by the FASINEX moored array was related to the westward propagation of the larger‐scale eddy/anomaly/frontal‐band pattern. The moored array was located within a warm‐anomaly feature during most of the experiment, which produced exceptionally warm conditions in the upper ocean. These anomalies are confined between 26° and 32°N, not only because the relatively large seasonal mean Tsy there allows horizontal eddy currents to force strong anomalies, but also because the baroclinic eddies with wavelengths of ≈800 km and periods of ≈200 days are confined to the STCZ. Large meridional variability exists in many properties of the eddy field, much of which can be traced to the influence of the Sargasso Sea mean current field on eddy variability

    A draft human pangenome reference

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    Here the Human Pangenome Reference Consortium presents a first draft of the human pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of genetically diverse individual

    Deep generative modeling for single-cell transcriptomics.

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    Single-cell transcriptome measurements can reveal unexplored biological diversity, but they suffer from technical noise and bias that must be modeled to account for the resulting uncertainty in downstream analyses. Here we introduce single-cell variational inference (scVI), a ready-to-use scalable framework for the probabilistic representation and analysis of gene expression in single cells ( https://github.com/YosefLab/scVI ). scVI uses stochastic optimization and deep neural networks to aggregate information across similar cells and genes and to approximate the distributions that underlie observed expression values, while accounting for batch effects and limited sensitivity. We used scVI for a range of fundamental analysis tasks including batch correction, visualization, clustering, and differential expression, and achieved high accuracy for each task
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