Shrimp Disease in Asia Resulting in High U.S. Import Prices

[Excerpt] Shrimp has become a popular purchase for American consumers, with U.S. consumption of shrimp reaching 3.8 pounds per person in 2012. Demand for shrimp has increased over the years, and shrimp is currently the largest imported seafood species, accounting for 29 percent of seafood imports by dollar value. In 2013, consumers and businesses found themselves paying higher prices with less product available in supermarkets and restaurants. For example, the popular restaurant chain Red Lobster recently saw a 35-percent increase in the price the company paid for shrimp. The price hike contributed to a 3.1-percent increase in the company’s overall food costs and, more recently, an 18-percent decrease in earnings during the quarter that ended in February 2014. Similarly, Noodles & Company noted that the cost of shrimp in its pasta dishes would rise 29 percent this year

Evaluation of the Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR) in a spinal cord injury population.

Spinal cord injury (SCI) is an acute and devastating event that results in significant and permanent life changes for the individuals who are injured, as well as their families and friends. Depression has received more attention from clinicians and researchers than any other psychological issue among persons with SCI. Measurement of depression in this population has a variety of methodological issues, including inconsistent assessments used (self-report versus clinical interviews), varying definitions of depression, inclusion and exclusion of physical symptoms in the assessment process, and use of measures that do not represent DSM-IV criteria for major depressive disorder. The primary goal of this study was to evaluate the Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR) and provide descriptive analyses of this measure with persons with SCI. Results showed that somatic symptoms were more frequently endorsed than psychological symptoms in this population. Additionally, scores on the QIDS-SR were significantly associated with a depression diagnosis in the patient's medical chart. However, QIDS-SR scores were not found to be correlated inversely with quality of life scores as predicted. The QIDS-SR was shown to have good internal consistency and convergent validity with patients with SCI. However, it failed to demonstrate construct validity. The QIDS-SR has the potential to be a valid measure with this population and further analysis of the psychometric properties with patients with SCI is warranted

Hubungan Kepercayaan Diri Dengan Komunikasi Interpersonal Pada Mahasiswa Angkatan 2013 Program Studi Ilmu Keperawatan Universitas Sam Ratulagi Manado

: Background In the interpersonal communication, confidence is needed because the recognition and appreciation of communication we will have if we have the confidence..Purpose to know The Relationship Between Interpersonal Communication with Confidence for Student class 2013 at Nursing Department, Sam Ratulangi University Manado. Design is observational analytic with approach cross sectional. Population entire student class of 2013 at Nursing Department, Sam Ratulangi University, with number 109 students and Sample use purposive sampling, with number 57 students. The data collected were processed using SPSS computer assistance (Statistical Programme For Social Science) version 20 using the chi-square test at 95% significance level (á 0.05).Result obtained value of P =0,152 more than á = 0,05 (p 0,05).Conclusion there is not relationship between interpersonal communication with confidence for student class 2013 at Nursing Department, Sam Ratulangi University Manado. Suggestion consideration for the department as teaching materials for courses Psychiatric Nursing, and the student is expected to improve the knowledge about confidence and interpersonal communication

Sister chromatid exchange and genomic instability in soft tissue sarcomas: potential implications for response to DNA-damaging treatments

Sarcomas are rare heterogenous malignancies of mesenchymal origin characterised by complex karyotypes but no specific abnormalities. Recurrence is common and metastatic disease carries poor survival despite standard DNA-damaging radiotherapy or chemotherapy. DNA double strand breaks (DSB) are either repaired by mechanisms such as homologous recombination (HR); or result in cell death by apoptosis. Endogenous γH2AX and SCE formation are early and late events, respectively and their levels are considered surrogate measures of genomic instability. Combined γH2AX and SCE analysis were used to evaluate endogenous DNA DSB levels (and their subsequent repair) in 9 primary sarcoma cell lines and compared with well-established commercial lines. All the sarcoma cell lines had elevated γH2AX and SCE levels, but there was no correlation between the DNA DSB frequency and subsequent SCE. Typically radio-resistant osteosarcoma cells had relatively low γH2AX frequency, but high SCE counts suggestive of efficient DNA repair. Conversely, liposarcoma cells derived from a radio-sensitive tumour had high H2AX but relatively lower SCE levels that may imply inefficient DNA DSB repair. To our knowledge, this is the first report that correlates H2AX and SCE levels in primary sarcoma cell lines and may provide insight into potential response to DNA damaging-treatments

Non-Coding RNA Sequencing of Equine Endometrium During Maternal Recognition of Pregnancy.

Maternal recognition of pregnancy (MRP) in the mare is not well defined. In a non-pregnant mare, prostaglandin F2α (PGF) is released on day 14 post-ovulation (PO) to cause luteal regression, resulting in loss of progesterone production. Equine MRP occurs prior to day 14 to halt PGF production. Studies have failed to identify a gene candidate for MRP, so attention has turned to small, non-coding RNAs. The objective of this study was to evaluate small RNA (<200 nucleotides) content in endometrium during MRP. Mares were used in a cross-over design with each having a pregnant and non-mated cycle. Each mare was randomly assigned to collection day 11 or 13 PO (n = 3/day) and endometrial biopsies were obtained. Total RNA was isolated and sequencing libraries were prepared using a small RNA library preparation kit and sequenced on a HiSeq 2000. EquCab3 was used as the reference genome and DESeq2 was used for statistical analysis. On day 11, 419 ncRNAs, representing miRNA, snRNA, snoRNA, scaRNA, and vaultRNA, were different between pregnancy statuses, but none on day 13. Equine endometrial ncRNAs with unknown structure and function were also identified. This study is the first to describe ncRNA transcriptome in equine endometrium. Identifying targets of these ncRNAs could lead to determining MRP

Generalized Sums over Histories for Quantum Gravity I. Smooth Conifolds

This paper proposes to generalize the histories included in Euclidean functional integrals from manifolds to a more general set of compact topological spaces. This new set of spaces, called conifolds, includes nonmanifold stationary points that arise naturally in a semiclasssical evaluation of such integrals; additionally, it can be proven that sequences of approximately Einstein manifolds and sequences of approximately Einstein conifolds both converge to Einstein conifolds. Consequently, generalized Euclidean functional integrals based on these conifold histories yield semiclassical amplitudes for sequences of both manifold and conifold histories that approach a stationary point of the Einstein action. Therefore sums over conifold histories provide a useful and self-consistent starting point for further study of topological effects in quantum gravity. Postscript figures available via anonymous ftp at black-hole.physics.ubc.ca (137.82.43.40) in file gen1.ps.Comment: 81pp., plain TeX, To appear in Nucl. Phys.

Phosphorus availability on many organically managed farms in Europe

Maintaining sufficient soil phosphorus (P) levels for non-limiting crop growth is challenging in organic systems since off-farm inputs of P are restricted. This study assessed the status of P on organic farms in Europe using soil test results for extractable P. Data was obtained from published literature, unpublished theses, and various national and regional databases of soil test values. Most of the data (15,506 observations) came from field scale soil tests, but in some cases (1272 observations) values had been averaged across a farm. Farm scale and field scale data were analysed separately and the impact of farm type (arable, dairy, grassland, horticulture, mixed, poultry, unknown) was assessed. Soil test results were assigned to P classes from very low (P class 1) to very high (P class 5). The farm scale data came primarily from Norway, Sweden and Switzerland and did not indicate deficiencies in extractable P; 93% of farms fell into class 3 or above. The majority of the field scale data came from Germany and indicated sufficient or higher levels of P availability for arable and grassland systems on 60% of fields; the remaining fields had low or very low available P. Adaptations in organic systems may improve P uptake and utilization efficiency allowing yields to be maintained in the short-term, nevertheless there is cause for concern about the long-term P sustainability of some organic farming systems in Europe. This highlights the need to reassess allowable P inputs in organic farming systems to improve overall sustainability

A School Nurse-Delivered Intervention for Overweight and Obese Adolescents: Lessons Learned

Dr. Pbert will present work from an academic and community partnership between UMMS and the School Health Unit of the Massachusetts Department of Public Health to design and test a brief intervention for school nurses to provide weight management assistance to overweight and obese adolescents in the school health setting. She will discuss why the school nurse and school health setting are promising venues for addressing adolescent overweight, present results from their pilot study, and discuss facilitators, barriers and strategies to implementing this treatment model

How to deal with missing longitudinal data in cost of illness analysis in Alzheimer’s disease—suggestions from the GERAS observational study

BACKGROUND: Missing data are a common problem in prospective studies with a long follow-up, and the volume, pattern and reasons for missing data may be relevant when estimating the cost of illness. We aimed to evaluate the effects of different methods for dealing with missing longitudinal cost data and for costing caregiver time on total societal costs in Alzheimer's disease (AD). METHODS: GERAS is an 18-month observational study of costs associated with AD. Total societal costs included patient health and social care costs, and caregiver health and informal care costs. Missing data were classified as missing completely at random (MCAR), missing at random (MAR) or missing not at random (MNAR). Simulation datasets were generated from baseline data with 10-40 % missing total cost data for each missing data mechanism. Datasets were also simulated to reflect the missing cost data pattern at 18 months using MAR and MNAR assumptions. Naïve and multiple imputation (MI) methods were applied to each dataset and results compared with complete GERAS 18-month cost data. Opportunity and replacement cost approaches were used for caregiver time, which was costed with and without supervision included and with time for working caregivers only being costed. RESULTS: Total costs were available for 99.4 % of 1497 patients at baseline. For MCAR datasets, naïve methods performed as well as MI methods. For MAR, MI methods performed better than naïve methods. All imputation approaches were poor for MNAR data. For all approaches, percentage bias increased with missing data volume. For datasets reflecting 18-month patterns, a combination of imputation methods provided more accurate cost estimates (e.g. bias: -1 % vs -6 % for single MI method), although different approaches to costing caregiver time had a greater impact on estimated costs (29-43 % increase over base case estimate). CONCLUSIONS: Methods used to impute missing cost data in AD will impact on accuracy of cost estimates although varying approaches to costing informal caregiver time has the greatest impact on total costs. Tailoring imputation methods to the reason for missing data will further our understanding of the best analytical approach for studies involving cost outcomes