200 research outputs found
Optimization of a condenser in a thermal power plant
Paper presented at the 9th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, Malta, 16-18 July, 2012.In this study, thermal power plant’s, based on Ideal Rankine Cycle, steam is condensed while the pressure of the condenser changes between 0.1 bar and 0.02 bar. The effect of this condensation on condenser area and effects to the cost is investigated. Change of rate of condenser area is calculated, relative to the condenser pressure drops. It is concluded that the area of condenser increases when the pressure of condenser decreases, accordingly the cooling water pump power changes. This result is discussed in the impact of energy production costs
Positive effects of angiotensin-converting enzyme (ACE) inhibitor, captopril, on pentylenetetrazole-induced epileptic seizures in mice
Purpose: To evaluate the effects of an angiotensin-converting enzyme (ACE) inhibitor, captopril, on pentylenetetrazole (PTZ)-induced seizures and post-seizure hippocampal injury.
Materials: Thirty-five male Balb-c mice weighing 30 - 33 g were divided into control, saline PTZ, s(erum physiologic 1 ml/kg as solvent), positive control (valproic acid 200 mg/kg), captopril (25 mg/kg/day for 7 days), and captopril (50 mg/kg/day for 7 days) groups. PTZ (60 mg/kg) was administered thirty minutes after medication administration to induce epileptic seizures. The animals were observed for 30 min to record Racine stages, the time of the first myoclonic jerk (FMJ), and the occurrence of the first generalized tonic-clonic seizure (GTCS). Cornu Ammonis (CA)1, CA2, CA3, and the dentate gyrus (DG) of the hippocampus underwent histopathological examinations. The levels of total oxidant status (TOS), oxidative stress markers (total antioxidant status, TAS), and oxidative stress index (OSI) were measured in the brain tissue.
Results: Compared to PTZ group, 25 mg/kg captopril decreased seizure scores and delayed FMJ and GTCS (p < 0.05). Histopathological assessment demonstrated that both 25 and 50 mg/kg captopril alleviated neuronal injury in CA1, CA2, CA3, and DG compared to PTZ (p < 0.05). Also, TOS and OSI levels in the brain tissue were reduced by both 25 and 50 mg/kg doses of captopril (p < 0.05).
Conclusion: Captopril favorably improves epileptic seizure parameters and acts against post-seizure neuronal injury in the hippocampus. Captopril may be a drug of choice in epileptic individuals with hypertension.
Keywords: Captopril, Angiotensin-converting enzyme, Epilepsy, Pentylenetetrazole, Neuronal damag
Thieno[3,2-b]thiophene and triphenylamine-based hole transport materials for perovskite solar cells
Heterocyclic compounds have played significant roles in achieving high performance as hole transport materials (HTMs) for perovskite solar cell (PSC) applications. Various studies have focused on the development of fused heterocyclic conjugated structures for hole transport materials. In this report, three novel π-extended conjugated materials (M1-M3), based on thieno[3,2-b]thiophene (TT) and 4,4′-dimethoxytriphenylamine [TPA(OMe)2], were designed and successfully synthesized via Palladium (0) catalyzed Suzuki coupling reaction. Their optical, electrochemical, and thermal properties were investigated by UV-Vis, fluorescence, cyclic voltammetry, and thermal analysis. The materials were utilized as hole transport materials in p-i-n architecture perovskite solar cells, which displayed performances of open-circuit voltage (Voc) as high as 1,050 mV, a maximum short-circuit current (Jsc) of 16,9 mA/cm2, a maximum fill factor (FF) of 29.3%, and a power conversion efficiency (PCE) of 5.20%. This work demonstrated that thieno[3,2-b]thiophene and TPA(OMe)2-based structures are promising cores for high-performance hole transport materials in perovskite solar cell architecture
The first clinical case due to AP92 like strain of Crimean-Congo Hemorrhagic Fever virus and a field survey
<p>Abstract</p> <p>Background</p> <p>Crimean-Congo Hemorrhagic Fever (CCHF) is a fatal infection, but no clinical case due to AP92 strain was reported. We described the first clinical case due to AP92 like CCHFV.</p> <p>Methods</p> <p>A case infected by a AP92 like CCHFV was detected in Balkanian part of Turkey. Diagnosis was confirmed by RT-PCR and sequencing. A human serologic and tick survey studies were performed in the region, where the case detected.</p> <p>Results</p> <p>Thirty eight individuals out of 741 were found to be anti CCHFV IgM positive. The attack rate for overall CCHFV was calculated as 5.2%. In univariate analyses, CCHFV IgM positivity was found to be associated with the age (p < 0.001), male gender (p = 0.001), agricultural activity (p = 0.036), and history of tick bite (p = 0.014). In multivariate analysis, older age (OR: 1.03, CI:1.01–1.05, p < 0.001), male gender were found to be the risk factors (OR: 2.5, CI:1.15–5.63, p = 0.020) for CCHFV infection.</p> <p>Conclusion</p> <p>This is the first human case with AP92 like CCHFV infection. Furthermore, this is the first report of AP92 like strain in Turkey. In the region, elderly males carry the highest risk for CCHFV infection.</p
Imported Crimean-Congo hemorrhagic fever cases in Istanbul
We described a series of imported cases of Crimean-Congo Hemorrhagic Fever (CCHF) in Istanbul and investigated the genetic diversity of the virus. All the suspected cases of CCHF, who were applied to the health centers in Istanbul, were screened for CCHF virus (CCHFv) infection by using semi-nested Polymerase Chain Reaction (PCR) following RT-PCR. Simultaneous blood samples were also sent to the national reference laboratory in Ankara for serologic investigation. In 10 out of 91 patients, CCHFv was detected by PCR, and among 9 out of 10, anti-CCHFv IgM antibodies were also positive. Clinical features were characterized by fever, myalgia, and hemorrhage. The levels of liver enzymes, creatinine phosphokinase, and lactate dehydrogenase were elevated, and bleeding markers were prolonged. All the cases were treated with ribavirin. There was no fatal case. All the strains clustered within the same group as other Europe/Turkey isolates
Ecology and classification of forests in Turkey
3rd International Geography Symposium (GEOMED) -- JUN 10-13, 2013 -- Antalya, TURKEYWOS: 000335821200089Turkey possesses all types of parent materials or bedrocks like metamorphic, sedimentary and volcanic belonging to different geological era and periods. Some parent materials contain evaporitic sediments with salt, gypsum and high contents of alkaline materials which mostly prevent the growth of climax vegetation. The country has a rugged and high topography, related to tectonic movements, and volcanic activities which mainly occurred in Tertiary and Quaternary eras. The mountains are divided into three groups in terms of formation and ecological importance namely; orogenic mountains, volcanic mountains and uplifted blocks or horst mountains. The ecological importance of the topography is fully stressed by altitude, aspect and climate. The forests in Turkey can be classified on the basis of ecological features as: humid-mild deciduous, humid-cold coniferous on the north facing slopes of coastal belt of Northern Anatolian Mountains; subhumid-cold continental coniferous in the north facing slopes of backward part of Northern Anatolian Mountains; subhumid-semiarid semi continental coniferous on the plateau and mountains of southern basins of northern Anatolian Mountains; semiarid continental timer Anatolia Quercus spp. - Juniper spp. - Pinus nigra, semiarid-subhumid Quercus spp., Mediterranean Pinus brutia and oro-Mediterranean coniferous. The excessive cutting, wrong silvicultural practices, opening of agricultural fields inside the forests, and clear-cutting system are changing the vegetation structure of forests. Some of the forests in the country are accepted as relict forests. (C) 2013 The Authors. Published by Elsevier Ltd
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