169 research outputs found
Authorship & Agency: Exploring Coaching as a Tool for Student Success
Coaching has emerged as a new, innovative practice within higher education. However, we have only begun to understand the true impact of coaching for college students. Research from individual coaching programs has shown that students who participate in coaching sessions are more likely to be retained, have higher GPAs, and engage in self-regulated learning. However, little research has been done to explore coaching from the student perspective. We do not yet understand how students utilize coaching as a tool to optimize their student experience. The goal of this project was to explore how coaching impacts the student experience and to illuminate ways in which coaching might help students develop self-authorship and agency. Using a phenomenological approach, data was generated through semi-structured interviews with 19 students at one university in the southeastern United States. Data analysis illuminated several major themes, including academic success strategies, decision-making, and independence, all of which help students optimize their college experience. Additionally, a perceived increased self-authorship and agency was demonstrated for most students, with first- and second-year students focused primarily on academic development, and junior and senior students focused on future planning and adulthood. Additional demographic features such as gender, major, and race/ethnicity were explored, but did not reveal any significant distinctions in the data
Biodistribution and PET Imaging of pharmacokinetics of manganese in mice using Manganese-52
<div><p>Manganese is essential to life, and humans typically absorb sufficient quantities of this element from a normal healthy diet; however, chronic, elevated ingestion or inhalation of manganese can be neurotoxic, potentially leading to <i>manganism</i>. Although imaging of large amounts of accumulated Mn(II) is possible by MRI, quantitative measurement of the biodistribution of manganese, particularly at the trace level, can be challenging. In this study, we produced the positron-emitting radionuclide <sup>52</sup>Mn (<i>t</i><sub><i>1/2</i></sub> = 5.6 d) by proton bombardment (<i>E</i><sub><i>p</i></sub><15 MeV) of chromium metal, followed by solid-phase isolation by cation-exchange chromatography. An aqueous solution of [<sup>52</sup>Mn]MnCl<sub>2</sub> was nebulized into a closed chamber with openings through which mice inhaled the aerosol, and a separate cohort of mice received intravenous (IV) injections of [<sup>52</sup>Mn]MnCl<sub>2</sub>. <i>Ex vivo</i> biodistribution was performed at 1 h and 1 d post-injection/inhalation (p.i.). In both trials, we observed uptake in lungs and thyroid at 1 d p.i. Manganese is known to cross the blood-brain barrier, as confirmed in our studies following IV injection (0.86%ID/g, 1 d p.i.) and following inhalation of aerosol, (0.31%ID/g, 1 d p.i.). Uptake in salivary gland and pancreas were observed at 1 d p.i. (0.5 and 0.8%ID/g), but to a much greater degree from IV injection (6.8 and 10%ID/g). In a separate study, mice received IV injection of an imaging dose of [<sup>52</sup>Mn]MnCl<sub>2</sub>, followed by <i>in vivo</i> imaging by positron emission tomography (PET) and <i>ex vivo</i> biodistribution. The results from this study supported many of the results from the biodistribution-only studies. In this work, we have confirmed results in the literature and contributed new results for the biodistribution of inhaled radiomanganese for several organs. Our results could serve as supporting information for environmental and occupational regulations, for designing PET studies utilizing <sup>52</sup>Mn, and/or for predicting the biodistribution of manganese-based MR contrast agents.</p></div
Opportunities for Departmental Strategic Planning: Enhancing the Experience for Incoming Transfer Students in the Department of Communication
The COMM 765: Strategic Planning & Communication Campaigns course conducted research on behalf of the Department of Communications to inform the future 2018-2023 planning and goals for the department. A quantitative survey was designed to examine key stakeholder groups including: faculty, staff, donors, current students and alumni. Each stakeholder group received a unique set of research questions. For example, donors were surveyed to determine their willingness, interest and knowledge of how to support department initiatives through the PSU Foundation; while current students were asked to share their thoughts on the effectiveness of current student organizations, and perceptions toward course developments and availability. All groups were provided with qualitative questions for gathering open-ended feedback. This oral presentation reports the findings from this study
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An opportunity for impact. Recommendations for regulating modern slavery in supply chains in Aotearoa New Zealand
This recommendation paper is published in the context of Aotearoa New Zealand recently entering public consultation for regulating modern slavery in supply chains. It provides direction for a legislative design that is compliant with international developments and, at the same time, considers Aotearoa New Zealand’s geopolitical and cultural context. It is not a response to the Government’s consultation proposal, but rather an independent resource, setting out recommendations based on research and the authors’ modern slavery law and practice expertise.
The recommendations are a resource for companies, governments, non-government organisations, academics and civil society, including to assist with submissions that these entities may wish to make
as part of the national consultation process. The following recommendations are made with an understanding that the Treaty of Waitangi/Te Tiriti o Waitangi principles are ensured and a Te Ao
Māori perspective is considered in any future legislative and policy developments in this area
New Constraints on Cosmic Reionization from the 2012 Hubble Ultra Deep Field Campaign
Understanding cosmic reionization requires the identification and
characterization of early sources of hydrogen-ionizing photons. The 2012 Hubble
Ultra Deep Field (UDF12) campaign has acquired the deepest infrared images with
the Wide Field Camera 3 aboard Hubble Space Telescope and, for the first time,
systematically explored the galaxy population deep into the era when cosmic
microwave background (CMB) data indicates reionization was underway. The UDF12
campaign thus provides the best constraints to date on the abundance,
luminosity distribution, and spectral properties of early star-forming
galaxies. We synthesize the new UDF12 results with the most recent constraints
from CMB observations to infer redshift-dependent ultraviolet (UV) luminosity
densities, reionization histories, and electron scattering optical depth
evolution consistent with the available data. Under reasonable assumptions
about the escape fraction of hydrogen ionizing photons and the intergalactic
medium clumping factor, we find that to fully reionize the universe by redshift
z~6 the population of star-forming galaxies at redshifts z~7-9 likely must
extend in luminosity below the UDF12 limits to absolute UV magnitudes of
M_UV\sim -13 or fainter. Moreover, low levels of star formation extending to
redshifts z~15-25, as suggested by the normal UV colors of z\simeq7-8 galaxies
and the smooth decline in abundance with redshift observed by UDF12 to
z\simeq10, are additionally likely required to reproduce the optical depth to
electron scattering inferred from CMB observations.Comment: Version accepted by ApJ (originally submitted Jan 5, 2013). The UDF12
website can be found at http://udf12.arizona.ed
Terrace reconstruction and long profile projection: a case study from the Solent river system near Southampton, England
River terrace sequences are important frameworks for archaeological evidence and as
such it is important to produce robust correlations between what are often fragmentary
remnants of ancient terraces. This paper examines both conceptual and practical issues
related to such correlations, using a case study from the eastern part of the former Solent
River system near Southampton, England. In this region two recent terrace schemes
have been constructed using different data to describe the terrace deposits: one based
mainly on terrace surfaces; the other on gravel thicknesses, often not recording the
terrace surface itself. The utility of each of these types of data in terrace correlation is
discussed in relation to the complexity of the record, the probability of post-depositional
alteration of surface sediments and comparison of straight-line projections with modern
river long profiles. Correlation using age estimates is also discussed, in relation to
optically-stimulated luminescence dating of sand lenses within terrace gravels in this
region during the PASHCC project. It is concluded that the need for replication at single
sites means that this approach has limited use for correlative purposes, although dating
of sediments is important for understanding wider landscape evolution and patterns of
human occupation
The Open Source GAITOR Suite for Rodent Gait Analysis
Locomotive changes are often associated with disease or injury, and these changes can be quantified through gait analysis. Gait analysis has been applied to preclinical studies, providing quantitative behavioural assessment with a reasonable clinical analogue. However, available gait analysis technology for small animals is somewhat limited. Furthermore, technological and analytical challenges can limit the effectiveness of preclinical gait analysis. The Gait Analysis Instrumentation and Technology Optimized for Rodents (GAITOR) Suite is designed to increase the accessibility of preclinical gait analysis to researchers, facilitating hardware and software customization for broad applications. Here, the GAITOR Suite’s utility is demonstrated in 4 models: a monoiodoacetate (MIA) injection model of joint pain, a sciatic nerve injury model, an elbow joint contracture model, and a spinal cord injury model. The GAITOR Suite identified unique compensatory gait patterns in each model, demonstrating the software’s utility for detecting gait changes in rodent models of highly disparate injuries and diseases. Robust gait analysis may improve preclinical model selection, disease sequelae assessment, and evaluation of potential therapeutics
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Experimental assessment of unvalidated assumptions in classical plasticity theory.
This report investigates the validity of several key assumptions in classical plasticity theory regarding material response to changes in the loading direction. Three metals, two rock types, and one ceramic were subjected to non-standard loading directions, and the resulting strain response increments were displayed in Gudehus diagrams to illustrate the approximation error of classical plasticity theories. A rigorous mathematical framework for fitting classical theories to the data, thus quantifying the error, is provided. Further data analysis techniques are presented that allow testing for the effect of changes in loading direction without having to use a new sample and for inferring the yield normal and flow directions without having to measure the yield surface. Though the data are inconclusive, there is indication that classical, incrementally linear, plasticity theory may be inadequate over a certain range of loading directions. This range of loading directions also coincides with loading directions that are known to produce a physically inadmissible instability for any nonassociative plasticity model
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