Pengaruh Pemberian Ekstrak Lengkuas (Alpinia Galanga) Terhadap Gambaran Histologik Payudara Mencit (Mus Musculus) Yang Diinduksi Benzo(a)pyrene

: Galangal (Alpinia galanga) is one of the plants that is often used for cancer therapy. Galangal contains different active ingredients, one of which is 1 'acetoxy chavicol acetate (ACA) which serves as an anticancer through its action as an anti-inflammatory agent, induction of apoptosis and inhibition of proliferation. Benzo(a)pyrenes (BAP) are five-ringed Polycyclic Aromatic Hydrocarbons (PAHs), a group of mutagenic and carcinogenic organic compounds. This study aimed to determine the effect of galangal extract on histological features of mice's breast induced by benzo(a)pyrene. This was an experimental laboratory study using mice as experimental animals. Subjects were 15 mice, divided into negative control group (5 mice) and two treatment groups (5 mice each). All mice were fed with standard pellet throughout the experiment. Mice in group A (negative control) received no treatment; mice in group B were administered with benzo(a)pyrene for 14 days then were given no treatment for the next 14 days; and mice in group C were induced by benzo(a)pyrene and were given galangal extract for 14 days then were given no treatment for the next 14 days. The result of this study revealed changes in mice breast histological features in the form of hyperplasia of cuboid epithelial cells of lactiferous ducts in group B and C, however the manifestation in group C was less pronounced than that was seen in group B. Conclusion: Oral administration of galangal extract subcutaneously was able to inhibit the cuboidal ductal lactiferious epithelial cell hyperplasia of mice breast induced by benzo(a)pyrene

Human Circadian Rhythms and the Shift Work Practices of Air Traffic Controllers

This research investigates human circadian rhythms and describes how they are affected by different types of shift work rotation patterns. Past studies have indicated that air traffic controllers prefer to work the type of rotation patterns that induce the negative result of circadian dysrhythmia. It has been established that workers experience decrements in performance from this condition. Recently, an alternate work schedule has allowed controllers to work new various rotation patterns, some of which disrupt circadian processes even more than previously preferred schedules. A descriptive analysis of controller work schedules from randomly selected facilities indicates that 16% of controllers are working the most disruptive type of schedules and that another 29% are working other dysrhythmia-inducing shift rotations. It is concluded that performance deficiencies are highly probable among these controllers and that tests should be conducted to determine the significance of the effect

Making the Case for New Research to Support the Integration of Small Unmanned Aircraft Systems into the National Airspace System

This paper describes the current state of sUAS regulation, their technical capabilities and the latest technologies that will allow for sUAS NAS integration. The research that is needed to demonstrate sUAS NAS integration capability is identified, and recommendations for conducting this necessary research are suggested

A Transformative Partnership between Socially and Historically Disadvantaged Farmers, 1890 Land Grant Institutions, and Walmart

Ensuring a sustainable future for socially and historically disadvantaged farmers (SHDFs) remains a central mission of many 1890 land grant universities. As major corporations adopt socially responsible and sustainable policies they are exploring new partnerships, including those with the aforementioned farmers and institutions. This article explores the opportunity presented by the partnership between Tuskegee University and Walmart during 2011, 2012, and 2013 that focused on assisting SHDFs to work together to expand their produce marketing opportunities to include large commercial retailers. This article provides perspective for the articles that follow in this issue of the Professional Agricultural Workers Journal (PAWJ). The articles focus specifically on microirrigation and solar powered pumps, integrated pest management, farm and food safety certification, challenges of forming the new cooperative, the role of Black women farmers, and progress made by the Sustainable Agriculture Consortium. Key Words: Sustainable Agriculture, Agricultural Cooperative, Small Farmers, Corporate Sustainabilit

Characteristics of contralateral carcinomas in patients with differentiated thyroid cancer larger than 1 cm

Purpose: Traditionally, total thyroidectomy has been advocated for patients with tumors larger than 1 cm. However, according to the ATA and NCCN guidelines (2015, USA), patients with tumors up to 4 cm are now eligible for lobectomy. A rationale for adhering to total thyroidectomy might be the presence of contralateral carcinomas. The purpose of this study was to describe the characteristics of contralateral carcinomas in patients with differentiated thyroid cancer (DTC) larger than 1 cm. Methods: A retrospective study was performed including patients from 17 centers in 5 countries. Adults diagnosed with DTC stage T1b-T3 N0-1a M0 who all underwent a total thyroidectomy were included. The primary endpoint was the presence of a contralateral carcinoma. Results: A total of 1

Side of onset in Parkinson's disease and alterations in religiosity: Novel behavioral phenotypes

Abstract. Behavioral neurologists have long been interested in changes in religiosity following circumscribed brain lesions. Advances in neuroimaging and cognitive experimental techniques have been added to these classical lesion-correlational approaches in attempt to understand changes in religiosity due to brain damage. In this paper we assess processing dynamics of religious cognition in patients with Parkinson's disease (PD). We administered a four-condition story-based priming procedure, and then covertly probed for changes in religious belief. Story-based priming emphasized mortality salience, religious ritual, and beauty in nature (Aesthetic). In neurologically intact controls, religious belief-scores significantly increased following the Aesthetic prime condition. When comparing effects of right (RO) versus left onset (LO) in PD patients, a double-dissociation in religious belief-scores emerged based on prime condition. RO patients exhibited a significant increase in belief following the Aesthetic prime condition and LO patients significantly increased belief in the religious ritual prime condition. Results covaried with executive function measures. This suggests lateral cerebral specialization for ritual-based (left frontal) versus aesthetic-based (right frontal) religious cognition. Patient-centered individualized treatment plans should take religiosity into consideration as a complex disease-associated phenomenon connected to other clinical variables and health outcomes