Screening of seaweed extracts against antibiotic resistant post operative infectious pathogens

Fifty five seaweed extracts belonging to 11 species of seaweeds were tested against post operative infectious drug resistant bacteria viz., E. coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Streptococcus pyogens, Staphylococcus aureus. Among the seaweed extracts, the acetone extracts of Caulerpa cupressoides shows maximum inhibtory activity against E. coli and propanol extracts of Gracilaria edulis shows maximum inhibitory effect against K. pneumoniae. Acetone extracts of Padina tetrastromatica and Laurencia cruciata show maximum inhibitory activity against P. aeruginosa, butanol extracts of Hypnea musciformis, Caulerpa cupressoides and Chaetomorpha linoides show maximum inhibitory effect against S. aureus

Secular Behavior of Exoplanets: Self-Consistency and Comparisons with the Planet-Planet Scattering Hypothesis

If mutual gravitational scattering among exoplanets occurs, then it may produce unique orbital properties. For example, two-planet systems that lie near the boundary between circulation and libration of their periapses could result if planet-planet scattering ejected a former third planet quickly, leaving one planet on an eccentric orbit and the other on a circular orbit. We first improve upon previous work that examined the apsidal behavior of known multiplanet systems by doubling the sample size and including observational uncertainties. This analysis recovers previous results that demonstrated that many systems lay on the apsidal boundary between libration and circulation. We then performed over 12,000 three-dimensional N-body simulations of hypothetical three-body systems that are unstable, but stabilize to two-body systems after an ejection. Using these synthetic two-planet systems, we test the planet-planet scattering hypothesis by comparing their apsidal behavior, over a range of viewing angles, to that of the observed systems and find that they are statistically consistent regardless of the multiplicity of the observed systems. Finally, we combine our results with previous studies to show that, from the sampled cases, the most likely planetary mass function prior to planet-planet scattering follows a power law with index -1.1. We find that this pre-scattering mass function predicts a mutual inclination frequency distribution that follows an exponential function with an index between -0.06 and -0.1.Comment: 29 pages, 3 figures, accepted for publication in A

“User Satisfaction on Library Resoures and Serviecs in St.Claret Degree College Library, Bangalore-A Study”

The main motive of this study was to examine and analyze the users’ satisfaction with library resources and services among the faculty members and students of St. Claret Degree College, Bangalore. The present study demonstrates the satisfaction levels of users towards various library resources and services provided by the college library. The result of the study found that a large number of respondents were satisfied with library resources and services. It also finds that the books had become a most widely used resources and circulation services was emerged most preferred service. Some suggestions have been given by the respondents to make about the library resources and services more effective and efficient manner

A novel method of staining acid-fast bacilli in sputum containers

Background & objectives: Making centrifuged deposit smears from sputum to detect acid-fast bacilli (AFB) is considered hazardous. We carried out this study to stain the centrifuged deposits with carbol-fuchsin in sputum containers and to decolourize and counterstain their smears made on glass slides. Methods: The centrifuged deposits of 180 sputum samples from pulmonary tuberculosis patients were used for making smears (initial deposit smears) and staining by Ziehl-Neelsen (ZN) method for the detection of AFB. Each of the sputum deposit was then treated with one ml of 1 per cent carbol-fuchsin and a smear made between 2 to 3 h was then decolourized and counterstained by the same procedures followed in ZN method (2 h stained deposit smear). The coded initial deposit smears and the corresponding 2 h stained deposit smears were read by the same readers and the results compared. Results: One hundred and fifty (70 positive and 80 negative) 2 h stained deposit smears were compared with initial deposit smears and the difference was not statistically significant. Interpretation & conclusion: Centrifuged deposits of sputum in sputum containers can be stained by carbol-fuchsin within 2-3 h and their smears made subsequently on glass slides can then be decolourized and counterstained by the procedures followed in ZN method for detection of AFB by light microscopy

A Multi-Resolution t-Mixture Model Approach to Robust Group-wise Alignment of Shapes

A novel probabilistic, group-wise rigid registration framework is proposed in this study, to robustly align and establish correspondence across anatomical shapes represented as unstructured point sets. Student’s t-mixture model (TMM) is employed to exploit their inherent robustness to outliers. The primary application for such a framework is the automatic construction of statistical shape models (SSMs) of anatomical structures, from medical images. Tools used for automatic segmentation and landmarking of medical images often result in segmentations with varying proportions of outliers. The proposed approach is able to robustly align shapes and establish valid correspondences in the presence of considerable outliers and large variations in shape. A multi-resolution registration (mrTMM) framework is also formulated, to further improve the performance of the proposed TMM-based registration method. Comparisons with a state-of-the art approach using clinical data show that the mrTMM method in particular, achieves higher alignment accuracy and yields SSMs that generalise better to unseen shapes

Critical depinning force and vortex lattice order in disordered superconductors

We simulate the ordering of vortices and its effects on the critical current in superconductors with varied vortex-vortex interaction strength and varied pinning strengths for a two-dimensional system. For strong pinning the vortex lattice is always disordered and the critical depinning force only weakly increases with decreasing vortex-vortex interactions. For weak pinning the vortex lattice is defect free until the vortex-vortex interactions have been reduced to a low value, when defects begin to appear with a simultaneous rapid increase in the critical depinning force. In each case the depinning force shows a maximum for non-interacting vortices. The relative height of the peak increases and the peak width decreases for decreasing pinning strength in excellent agreement with experimental trends associated with the peak effect. We show that scaling relations exist between the distance between defects in the vortex lattice and the critical depinning force.Comment: 5 pages, 6 figure

IMAGES II. A surprisingly low fraction of undisturbed rotating spiral disks at z~0.6: The morpho-kinematical relation 6 Gyrs ago

We present a first combined analysis of the morphological and dynamical properties for the Intermediate MAss Galaxy Evolution Sequence (IMAGES) sample. It is a representative sample of 52 z~0.6 galaxies with Mstell from 1.5 to 15 10^10Msun and possessing 3D resolved kinematics and HST deep imaging in at least two broad band filters. We aim at evaluate robustly the evolution of rotating spirals since z~0.6, as well as to test the different schemes for classifying galaxies morphologically. We used all the information provided by multi-band images, color maps and 2 dimensional light fitting to assign to each object a morphological class. We divided our sample between spiral disks, peculiar objects, compact objects and mergers. Using our morphological classification scheme, 4/5 of identified spirals are rotating disks and more than 4/5 of identified peculiar galaxies show complex kinematics, while automatic classification methods such as Concentration-Asymmetry and GINI-M20 severely overestimate the fraction of relaxed disk galaxies. Using this methodology, we find that the fraction of rotating spirals has increased by a factor ~ 2 during the last 6 Gyrs, a much higher fraction that found previously based on morphologies alone. These rotating spiral disks are forming stars very rapidly, doubling their stellar masses over the last 6 Gyrs, while most of their stars have been formed few Gyrs earlier, which reveals the presence of a large gas supply. Because they are likely the progenitors of local spirals, we can conjecture how their properties are evolving. Their disks show some evidence for an inside-out growth and the gas supply/accretion is not made randomly as the disk need to be stable in order to match the local disk properties.Comment: Typos corrected, reference adde

Status of DDT and pyrethroid resistance in Indian aedes Albopictus and absence of knockdown resistance (kdr) mutation

Background & objectives: Aedes albopictus is one of the vectors for dengue and chikungunya and emergence of pyrethroid resistance in this species could be of a major concern in controlling the vector. This study reports insecticide susceptibility status of Ae. albopictus to DDT and pyrethroids in some Indian populations and status of presence of knockdown resistance (kdr) mutations. Methods: Three to four day old adult female Ae. albopictus collected from Delhi, Gurgaon (Haryana), Hardwar (Uttarakhand), Guwahati (Assam) and Kottayam (Kerala) were bio-assayed with DDT (4), permethrin (0.75) and deltamethrin (0.05) impregnated papers using WHO standard susceptibility test kit. Mosquitoes were PCRgenotyped for F1534C kdr-mutation in the voltage-gated sodium channel (VGSC) gene. DDT and pyrethroid resistant individuals were sequenced for partial domain II, III and IV of VGSC targeting residues S989, I1011, V1016, F1534 and D1794 where kdr mutations are reported in Ae. aegypti. Results: Adult bioassays revealed varying degree of resistance against DDT among five populations of Ae. albopictus with corrected mortalities ranging between 61 and 92. Kerala and Delhi populations showed incipient resistance against permethrin and deltamethrin respectively. All other populations were susceptible for both the synthetic pyrethroids. None of the kdr mutations was detected in any of DDT, deltamethrin and permethrin resistant individuals. Interpretation & conclusion: Ae. albopictus has developed resistance against DDT and there is emergence of incipient resistance against pyrethroids in some populations. So far, there is no evidence of presence of knockdown resistance (kdr) mutation in Ae. albopictus. © 2015, Malaria Research Center. All right reserved