How good are the simulations of tropical SST–rainfall relationship by IPCC AR4 atmospheric and coupled models?

The failure of atmospheric general circulation models (AGCMs) forced by prescribed SST to simulate and predict the interannual variability of Indian/Asian monsoon has been widely attributed to their inability to reproduce the actual sea surface temperature (SST)–rainfall relationship in the warm Indo-Pacific oceans. This assessment is based on a comparison of the observed and simulated correlation between the rainfall and local SST. However, the observed SSTconvection/rainfall relationship is nonlinear and for this a linear measure such as the correlation is not an appropriate measure. We show that the SST– rainfall relationship simulated by atmospheric and coupled general circulation models in IPCC AR4 is nonlinear, as observed, and realistic over the tropical West Pacific (WPO) and the Indian Ocean (IO). The SST–rainfall pattern simulated by the coupled versions of these models is rather similar to that from the corresponding atmospheric one, except for a shift of the entire pattern to colder/warmer SSTs when there is a cold/warm bias in the coupled version

Towards AI enabled automated tracking of multiple boxers

Continuous tracking of boxers across multiple training sessions helps quantify traits required for the well-known ten-point-must system. However, continuous tracking of multiple athletes across multiple training sessions remains a challenge, because it is difficult to precisely segment bout boundaries in a recorded video stream. Furthermore, re-identification of the same athlete over different period or even within the same bout remains a challenge. Difficulties are further compounded when a single fixed view video is captured in top-view. This work summarizes our progress in creating a system in an economically single fixed top-view camera. Specifically, we describe improved algorithm for bout transition detection and in-bout continuous player identification without erroneous ID updation or ID switching. From our custom collected data of ~11 hours (athlete count: 45, bouts: 189), our transition detection algorithm achieves 90% accuracy and continuous ID tracking achieves IDU=0, IDS=0

Cognitive Workload Analysis of Fighter Aircraft Pilots in Flight Simulator Environment

Maintaining and balancing an optimal level of workload is essential for completing the task productively. Fighter aircraft is one such example, where the pilot is loaded heavily both physically (due to G manoeuvering) and cognitively (handling multiple sensors, perceiving, processing and multi-tasking including communications and handling weapons) to fulfill the combat mission requirements. This cognitive demand needs to be analysed to understand the workload of fighter pilot. Objective of this study is to analyse dynamic workload of fighter pilots in a realistic high-fidelity flight simulator environment during different flying workload conditions. The various workload conditions are (a) normal visibility, (b) low visibility, (c) normal visibility with secondary task, and (d) low visibility with secondary task. Though, pilot’s flying performance score was good, the physiological measure like heart rate variability (HRV) features and subjective assessment (NASA-TLX) components are found to be statistically significant (p<0.05) between tasks. HRV features such as SD2, SDNN, VLF and total power are found to be significant at all task load conditions. The features LFnu and HFnu are able to differentiate the effect of low visibility and secondary cognitive task, which was imposed as increased task in this study. This result benefits to understand the pilot’s task and performance at each flying phase and their cognitive demands during dynamic workload using HRV, which could assist pilot’s training schedule in optimal way on simulators as well as in actual flight conditions

Reproducibility of linear and angular cephalometric measurements obtained by an artificial-intelligence assisted software (WebCeph) in comparison with digital software (AutoCEPH) and manual tracing method

ABSTRACT Introduction: It has been suggested that human errors during manual tracing of linear/angular cephalometric parameters can be eliminated by using computer-aided analysis. The landmarks, however, are located manually and the computer system completes the analysis. With the advent of Artificial Intelligence in the field of Dentistry, automatic location of the landmarks has become a promising tool in digital Orthodontics. Methods: Fifty pretreatment lateral cephalograms obtained from the Orthodontic department of SRM dental college (India) were used. Analysis were done by the same investigator using the following methods: WebCeph™, AutoCEPH© for Windows or manual tracing. Landmark identification was carried out automatically by Artificial Intelligence in WebCeph™ and with a mouse driven cursor in AutoCEPH©, and manually using acetate sheet and 0.3-mm pencil, ruler and a protractor. The mean differences of the cephalometric parameters obtained between the three methods were calculated using ANOVA with statistical significance set at p0.75 indicated good agreement. Results: Intraclass correlation coefficient between the three groups was >0.830, showing good level of agreement, and the value within each group was >0.950, indicating high intrarater reliability. Conclusion: Artificial Intelligence assisted software showed good agreement with AutoCEPH© and manual tracing for all the cephalometric measurements

Disease Surveillance on Complex Social Networks

As infectious disease surveillance systems expand to include digital, crowd-sourced, and social network data, public health agencies are gaining unprecedented access to high-resolution data and have an opportunity to selectively monitor informative individuals. Contact networks, which are the webs of interaction through which diseases spread, determine whether and when individuals become infected, and thus who might serve as early and accurate surveillance sensors. Here, we evaluate three strategies for selecting sensors—sampling the most connected, random, and friends of random individuals—in three complex social networks—a simple scale-free network, an empirical Venezuelan college student network, and an empirical Montreal wireless hotspot usage network. Across five different surveillance goals—early and accurate detection of epidemic emergence and peak, and general situational awareness—we find that the optimal choice of sensors depends on the public health goal, the underlying network and the reproduction number of the disease (R0). For diseases with a low R0, the most connected individuals provide the earliest and most accurate information about both the onset and peak of an outbreak. However, identifying network hubs is often impractical, and they can be misleading if monitored for general situational awareness, if the underlying network has significant community structure, or if R0 is high or unknown. Taking a theoretical approach, we also derive the optimal surveillance system for early outbreak detection but find that real-world identification of such sensors would be nearly impossible. By contrast, the friends-of-random strategy offers a more practical and robust alternative. It can be readily implemented without prior knowledge of the network, and by identifying sensors with higher than average, but not the highest, epidemiological risk, it provides reasonably early and accurate information

3-(4-Bromo­phen­yl)quinazolin-4(3H)-one

In the title compound, C14H9BrN2O, the quinazoline unit is essentially planar, with a mean deviation of 0.058 (2) Å from the least-squares plane defined by the ten constituent ring atoms. The dihedral angle between the mean plane of the quinazoline ring system and the 4-bromo­phenyl ring is 47.6 (1)°. In the crystal, mol­ecules are linked by inter­molecular C—H⋯N and C—H⋯O hydrogen bonds, forming infinite chains of alternating R 2 2(6) dimers and R 2 2(14) ring motifs

Dissecting DNA repair in adult high grade gliomas for patient stratification in the post-genomic era

Deregulation of multiple DNA repair pathways may contribute to aggressive biology and therapy resistance in gliomas. We evaluated transcript levels of 157 genes involved in DNA repair in an adult glioblastoma Test set (n=191) and validated in ‘The Cancer Genome Atlas’ (TCGA) cohort (n=508). A DNA repair prognostic index model was generated. Artificial neural network analysis (ANN) was conducted to investigate global gene interactions. Protein expression by immunohistochemistry was conducted in 61 tumours. A fourteen DNA repair gene expression panel was associated with poor survival in Test and TCGA cohorts. A Cox multivariate model revealed APE1, NBN, PMS2, MGMT and PTEN as independently associated with poor prognosis. A DNA repair prognostic index incorporating APE1, NBN, PMS2, MGMT and PTEN stratified patients in to three prognostic sub-groups with worsening survival. APE1, NBN, PMS2, MGMT and PTEN also have predictive significance in patients who received chemotherapy and/or radiotherapy. ANN analysis of APE1, NBN, PMS2, MGMT and PTEN revealed interactions with genes involved in transcription, hypoxia and metabolic regulation. At the protein level, low APE1 and low PTEN remain associated with poor prognosis. In conclusion, multiple DNA repair pathways operate to influence biology and clinical outcomes in adult high grade gliomas