624 research outputs found
Inhibition of human natural killer cell activity by (14R,15S)-14,15-dihydroxy-5Z,8Z,10E,12E- icosatetraenoic acid.
High-resolution observations of gas and dust around Mira using ALMA and SPHERE/ZIMPOL
The outflows of oxygen-rich asymptotic giant branch (AGB) stars are thought to be driven by radiation pressure due to the scattering of photons on relatively large grains, with sizes of tenths of microns. The details of the formation of dust in the extended atmospheres of these stars and, therefore, the mass-loss process, is still not well understood. Aims. We aim to constrain the distribution of the gas and the composition and properties of the dust grains that form in the inner circumstellar environment of the archetypal Mira variable o Cet. Methods. We obtained quasi-simultaneous observations using ALMA and SPHERE/ZIMPOL on the Very Large Telescope (VLT) to probe the distribution of gas and large dust grains, respectively. Results. The polarized light images show dust grains around Mira A, but also around the companion, Mira B, and a dust trail that connects the two sources. The ALMA observations show that dust around Mira A is contained in a high-gas-density region with a significant fraction of the grains that produce the polarized light located at the edge of this region. Hydrodynamical and wind-driving models show that dust grains form efficiently behind shock fronts caused by stellar pulsation or convective motions. The distance at which we observe the density decline (a few tens of au) is, however, significantly larger than expected for stellar-pulsation-induced shocks. Other possibilities for creating the high-gas-density region are a recent change in the mass-loss rate of Mira A or interactions with Mira B. We are not able to determine which of these scenarios is correct. We constrained the gas density, temperature, and velocity within a few stellar radii from the star by modelling the CO v = 1, J = 3-2 line. We find a mass (~3.8 \ub1 1.3)
7 104 M to be contained between the stellar millimetre photosphere, R338 GHz, and 4 R338 GHz. Our best-fit models with lower masses also reproduce the 13CO v = 0, J = 3-2 line emission from this region well. We find TiO2 and AlO abundances corresponding to 4.5% and <0.1% of the total titanium and aluminium expected for a gas with solar composition. The low abundance of AlO allows for a scenario in which Al depletion into dust happens already very close to the star, as expected from thermal dust emission observations and theoretical calculations of Mira variables. The relatively large abundance of aluminium for a gas with solar composition allows us to constrain the presence of aluminium oxide grains based on the scattered light observations and on the gas densities we obtain. These models imply that aluminium oxide grains could account for a significant fraction of the total aluminium atoms in this region only if the grains have sizes 0.02 μm. This is an order of magnitude smaller than the maximum sizes predicted by dust-formation and wind-driving models. Conclusions. The study we present highlights the importance of coordinated observations using different instruments to advance our understanding of dust nucleation, dust growth, and wind driving in AGB stars
Unexpectedly large mass loss during the thermal pulse cycle of the red giant R Sculptoris!
The asymptotic giant branch star R Sculptoris is surrounded by a detached
shell of dust and gas. The shell originates from a thermal pulse during which
the star undergoes a brief period of increased mass loss. It has hitherto been
impossible to constrain observationally the timescales and mass-loss properties
during and after a thermal pulse - parameters that determine the lifetime on
the asymptotic giant branch and the amount of elements returned by the star.
Here we report observations of CO emission from the circumstellar envelope and
shell around R Sculptoris with an angular resolution of 1.3 arcsec. What was
hitherto thought to be only a thin, spherical shell with a clumpy structure, is
revealed to contain a spiral structure. Spiral structures associated with
circumstellar envelopes have been seen previously, from which it was concluded
that the systems must be binaries. Using the data, combined with hydrodynamic
simulations, we conclude that R Sculptoris is a binary system that underwent a
thermal pulse approximately 1800 years ago, lasting approximately 200 years.
About 0.003 Msun of mass was ejected at a velocity of 14.3 km s-1 and at a rate
approximately 30 times higher than the prepulse mass-loss rate. This shows that
approximately 3 times more mass is returned to the interstellar medium during
and immediately after a pulse than previously thought.Comment: Accepted by Natur
The ATLAS tile calorimeter digitizer
The ATLAS Tile Calorimeter digitizer system samples photomultiplier signals from the scintillating tiles of the hadronic calorimeter. For each channel a pair of 10-bit ADCs digitize high and low gain signals at 40.08 MHz to provide the necessary 16-bit dynamic range. The sampled data is temporarily stored in digital pipelines for up to 6.375 \mus, awaiting a level-1 accept. For each accept received, the corresponding sampled pulse is transferred to a derandomizer buffer for subsequent readout to the data acquisition system (DAQ). The main functionality of the digitizer is implemented in radiation tolerant ASICs, using a fault tolerant architecture to minimize the consequences of radiation induced faults
The wonderful complexity of the Mira AB system
We have mapped the CO(3-2) line emission around the Mira AB system at 0.5
resolution using the Atacama Large Millimeter/submillimeter Array (ALMA). The
CO map shows amazing complexity. The circumstellar gas has been shaped by
different dynamical actors during the evolution of the system and several
morphological components can be identified. The companion is marginally
resolved in continuum emission and is currently at 0.4870.006 separation.
In the main line component, centered on the stellar velocity, spiral arcs
around Mira A are found. The spiral appears to be relatively flat and oriented
in the orbital plane. An accretion wake behind the companion is clearly visible
and the projected arc separation is of order 5''. In the blue wing of the line
emission, offset from the main line, several large (5-10''), opposing
arcs are found. We tentatively suggest that this structure is created by the
wind of Mira B blowing a bubble in the expanding envelope of Mira A.Comment: Letter accepted in A&
Estimating the public health impact of disbanding a government alcohol monopoly: Application of new methods to the case of Sweden
Background: Government alcohol monopolies were created in North America and Scandinavia to limit health and social problems. The Swedish monopoly, Systembolaget, reports to a health ministry and controls the sale of all alcoholic beverages with > 3.5% alcohol/volume for off-premise consumption, within a public health mandate. Elsewhere, alcohol monopolies are being dismantled with evidence of increased consumption and harms. We describe innovative modelling techniques to estimate health outcomes in scenarios involving Systembolaget being replaced by 1) privately owned liquor stores, or 2) alcohol sales in grocery stores. The methods employed can be applied in other jurisdictions and for other policy changes. Methods: Impacts of the privatisation scenarios on pricing, outlet density, trading hours, advertising and marketing were estimated based on Swedish expert opinion and published evidence. Systematic reviews were conducted to estimate impacts on alcohol consumption in each scenario. Two methods were applied to estimate harm impacts: (i) alcohol attributable morbidity and mortality were estimated utilising the International Model of Alcohol Harms and Policies (InterMAHP); (ii) ARIMA methods to estimate the relationship between per capita alcohol consumption and specific types of alcohol-related mortality and crime. Results: Replacing government stores with private liquor stores (Scenario 1) led to a 20.0% (95% CI, 15.3-24.7) increase in per capita consumption. Replacement with grocery stores (Scenario 2) led to a 31.2% (25.1-37.3%) increase. With InterMAHP there were 763 or + 47% (35-59%) and 1234 or + 76% (60-92%) more deaths per year, for Scenarios 1 and 2 respectively. With ARIMA, there were 850 (334-1444) more deaths per year in Scenario 1 and 1418 more in Scenario 2 (543-2505). InterMAHP also estimated 10,859 or + 29% (22-34%) and 16,118 or + 42% (35-49%) additional hospital stays per year respectively. Conclusions: There would be substantial adverse consequences for public health and safety were Systembolaget to be privatised. We demonstrate a new combined approach for estimating the impact of alcohol policies on consumption and, using two alternative methods, alcohol-attributable harm. This approach could be readily adapted to other policies and settings. We note the limitation that some significant sources of uncertainty in the estimates of harm impacts were not modelled
The extended molecular envelope of the asymptotic giant branch star π1 Gruis as seen by ALMA II. The spiral-outflow observed at high-angular resolution
Context. This study is a follow up to the previous analysis of lower-angular resolution data in which the kinematics and structure of the circumstellar envelope (CSE) around the S-type asymptotic giant branch (AGB) star pi(1) Gruis were investigated. The AGB star has a known companion (at a separation of 400 AU) that cannot explain the strong deviations from spherical symmetry of the CSE. Recently, hydrodynamic simulations of mass transfer in closer binary systems have successfully reproduced the spiral-shaped CSEs found around a handful of sources. There is growing evidence for an even closer, undetected companion complicating the case of pi(1) Gruis further. Aims. The improved spatial resolution allows for the investigation of the complex circumstellar morphology and the search for imprints on the CSE of the third component. Methods. We have observed the (CO)-C-12 J = 3-2 line emission from pi(1) Gruis using both the compact and extended array of Atacama Large Millimeter/submillimeter Array (ALMA). The interferometric data have furthermore been combined with data from the ALMA total power array. The imaged brightness distribution has been used to constrain a non-local, non-local thermodynamic equilibrium 3D radiative transfer model of the CSE. Results. The high-angular resolution ALMA data have revealed the first example of a source on the AGB where both a faster bipolar outflow and a spiral pattern along the orbital plane can be seen in the gas envelope. The spiral can be traced in the low- to intermediate-velocity (13-25 km s(-1)) equatorial torus. The largest spiral-arm separation is approximate to 5.\u27\u27 5 and consistent with a companion with an orbital period of approximate to 330 yr and a separation of less than 70 AU. The kinematics of the bipolar outflow is consistent with it being created during a mass-loss eruption where the mass-loss rate from the system increased by at least a factor of five for 10-15 yr. Conclusions. The spiral pattern is the result of an undetected companion. The bipolar outflow is the result of a rather recent mass-loss eruption event
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