24 research outputs found

    Perspectives for implementing fisheries certification in developing countries

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    This paper discusses the future of the Marine Stewardship Council (MSC), a market-based certification program, in developing countries and exposes the challenges and opportunities for fish producers. The MSC needs to attract the interest of more fishing enterprises from these regions to increase its global presence. Because most fisheries in developing countries cannot meet the MSC standards, or afford the certification process costs, it is suggested that there is a need for developing different levels within the MSC system and additional third-party assessing organizations. MSC certification may mean adoption of improvements in fisheries management and approving fishing regimes in developing countries. However, post-certification benefits may decrease as more fisheries become certified

    Saturday night purpura: An uncommon presentation of exercise-induced vasculitis

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    Exercise-induced vasculitis (EIV) is a benign cutaneous vasculitis that affects healthy individuals. We report a case of EIV in a 15-year-old male patient with a striking clinical appearance triggered by a combination of prolonged standing and disco dancing in a warm environment. Pediatric dermatologists should be aware of this activity as a possible trigger of EIV, especially in teenagers

    The effect of vibration therapy on neck myofascial trigger points: A randomized controlled pilot study

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    [EN] Background: The purpose of this study was to evaluate the effect of low-frequency self-administered vibration therapy into myofascial trigger points in the upper trapezius and levator scapulae on patients with chronic non-specific neck pain. Methods: Twenty-eight patients with chronic non-specific neck pain were randomly assigned into a vibration group, receiving 10 self-applied sessions of vibration therapy in the upper trapezius and levator scapulae trigger points; or a control group, receiving no intervention. Self-reported neck pain and disability (Neck Disability Index) and pressure pain threshold were assessed at baseline and after the first, fifth and 10th treatment sessions. Findings: Significant differences were found in the vibration group when compared to the control group after the treatment period: the vibration group reached lower Neck Disability Index scores (F = 4.74, P = .033, eta(2) = 0.07) and greater pressure pain threshold values (F = 7.56, P = .01, eta(2) = 0.10) than the control group. The vibration group reported a significant reduction in Neck Disability Index scores (chi(2) = 19,35, P = .00, Kendall's W = 0.28) and an increase in pressure pain threshold (chi(2) = 87,10, P = .00, Kendall's W = 0.73) between the assessment times over the course of the treatment. The mean increase in pressure pain threshold in the vibration group after the 10 sessions was 8.54 N/cm2, while the mean reduction in Neck Disability Index scores was 4.53 points. Interpretation: Vibration therapy may be an effective intervention for reducing self-reported neck pain and disability and pressure pain sensitivity in patients with chronic non-specific neck pain. This tool could be recommended for people with non-specific neck pain.Dueñas, L.; Zamora, T.; Lluch, E.; Artacho Ramírez, MÁ.; Mayoral, O.; Balasch Parisi, S.; Balasch-Bernat, M. (2020). The effect of vibration therapy on neck myofascial trigger points: A randomized controlled pilot study. Clinical Biomechanics. 78:1-9. https://doi.org/10.1016/j.clinbiomech.2020.1050711978Andrade Ortega, J. A., Delgado Martínez, A. D., & Ruiz, R. A. (2010). Validation of the Spanish Version of the Neck Disability Index. Spine, 35(4), E114-E118. doi:10.1097/brs.0b013e3181afea5dArmstrong, W. J., Grinnell, D. C., & Warren, G. S. (2010). The Acute Effect of Whole-Body Vibration on the Vertical Jump Height. Journal of Strength and Conditioning Research, 24(10), 2835-2839. doi:10.1519/jsc.0b013e3181e271ccBal, M. I., Sattoe, J. N. T., Roelofs, P. D. D. M., Bal, R., van Staa, A., & Miedema, H. S. (2016). Exploring effectiveness and effective components of self-management interventions for young people with chronic physical conditions: A systematic review. Patient Education and Counseling, 99(8), 1293-1309. doi:10.1016/j.pec.2016.02.012Bishop, M. D., Mintken, P., Bialosky, J. E., & Cleland, J. A. (2013). Patient Expectations of Benefit From Interventions for Neck Pain and Resulting Influence on Outcomes. Journal of Orthopaedic & Sports Physical Therapy, 43(7), 457-465. doi:10.2519/jospt.2013.4492Cagnie, B., Dewitte, V., Barbe, T., Timmermans, F., Delrue, N., & Meeus, M. (2013). Physiologic Effects of Dry Needling. Current Pain and Headache Reports, 17(8). doi:10.1007/s11916-013-0348-5Cagnie, B., Castelein, B., Pollie, F., Steelant, L., Verhoeyen, H., & Cools, A. (2015). Evidence for the Use of Ischemic Compression and Dry Needling in the Management of Trigger Points of the Upper Trapezius in Patients with Neck Pain. American Journal of Physical Medicine & Rehabilitation, 94(7), 573-583. doi:10.1097/phm.0000000000000266Celik, D., & Mutlu, E. K. (2013). Clinical Implication of Latent Myofascial Trigger Point. Current Pain and Headache Reports, 17(8). doi:10.1007/s11916-013-0353-8Chan, Y.-C., Wang, T.-J., Chang, C.-C., Chen, L.-C., Chu, H.-Y., Lin, S.-P., & Chang, S.-T. (2015). Short-term effects of self-massage combined with home exercise on pain, daily activity, and autonomic function in patients with myofascial pain dysfunction syndrome. Journal of Physical Therapy Science, 27(1), 217-221. doi:10.1589/jpts.27.217Chesterton, L. S., Barlas, P., Foster, N. E., Baxter, D. G., & Wright, C. C. (2003). Gender differences in pressure pain threshold in healthy humans. Pain, 101(3), 259-266. doi:10.1016/s0304-3959(02)00330-5Cummings, M., & Baldry, P. (2007). Regional myofascial pain: diagnosis and management. 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Pain, 77(1), 73-79. doi:10.1016/s0304-3959(98)00084-0Giamberardino, M. A., Affaitati, G., Fabrizio, A., & Costantini, R. (2011). Myofascial pain syndromes and their evaluation. Best Practice & Research Clinical Rheumatology, 25(2), 185-198. doi:10.1016/j.berh.2011.01.002Gross, A. R., Paquin, J. P., Dupont, G., Blanchette, S., Lalonde, P., Cristie, T., … Bronfort, G. (2016). Exercises for mechanical neck disorders: A Cochrane review update. Manual Therapy, 24, 25-45. doi:10.1016/j.math.2016.04.005Hong, C.-Z., Chen, Y.-C., Pon, C. H., & Yu, J. (1993). Immediate Effects of Various Physical Medicine Modalities on Pain Threshold of an Active Myofascial Trigger Point. Journal of Musculoskeletal Pain, 1(2), 37-53. doi:10.1300/j094v01n02_04Hutting, N., Johnston, V., Staal, J. B., & Heerkens, Y. F. (2019). Promoting the Use of Self-management Strategies for People With Persistent Musculoskeletal Disorders: The Role of Physical Therapists. Journal of Orthopaedic & Sports Physical Therapy, 49(4), 212-215. doi:10.2519/jospt.2019.0605Itoh, K., Okada, K., & Kawakita, K. (2004). A Proposed Experimental Model of Myofascial Trigger Points in Human Muscle after Slow Eccentric Exercise. Acupuncture in Medicine, 22(1), 2-13. doi:10.1136/aim.22.1.2Jahr, S., Schoppe, B., & Reisshauer, A. (2008). Effect of treatment with low-intensity and extremely low-frequency electrostatic fields (Deep Oscillation®) on breast tissue and pain in patients with secondary breast lymphoedema. Journal of Rehabilitation Medicine, 40(8), 645-650. doi:10.2340/16501977-0225Järvinen, T. A. H., Järvinen, T. L. N., Kääriäinen, M., Äärimaa, V., Vaittinen, S., Kalimo, H., & Järvinen, M. (2007). Muscle injuries: optimising recovery. Best Practice & Research Clinical Rheumatology, 21(2), 317-331. doi:10.1016/j.berh.2006.12.004Jonkman, N. H., Schuurmans, M. J., Jaarsma, T., Shortridge-Baggett, L. M., Hoes, A. W., & Trappenburg, J. C. A. (2016). Self-management interventions: Proposal and validation of a new operational definition. Journal of Clinical Epidemiology, 80, 34-42. doi:10.1016/j.jclinepi.2016.08.001Kim, D.-H., Yoon, D. M., & Yoon, K. B. (2015). The Effects of Myofascial Trigger Point Injections on Nocturnal Calf Cramps. The Journal of the American Board of Family Medicine, 28(1), 21-27. doi:10.3122/jabfm.2015.01.140151Kraft, K., Kanter, S., & Janik, H. (2013). Safety and Effectiveness of Vibration Massage by Deep Oscillations: A Prospective Observational Study. Evidence-Based Complementary and Alternative Medicine, 2013, 1-10. doi:10.1155/2013/679248Lauche, R., Cramer, H., Hohmann, C., Choi, K.-E., Rampp, T., Saha, F. J., … Dobos, G. (2012). The Effect of Traditional Cupping on Pain and Mechanical Thresholds in Patients with Chronic Nonspecific Neck Pain: A Randomised Controlled Pilot Study. Evidence-Based Complementary and Alternative Medicine, 2012, 1-10. doi:10.1155/2012/429718Lluch, E., Arguisuelas, M. D., Coloma, P. S., Palma, F., Rey, A., & Falla, D. (2013). Effects of Deep Cervical Flexor Training on Pressure Pain Thresholds Over Myofascial Trigger Points in Patients With Chronic Neck Pain. Journal of Manipulative and Physiological Therapeutics, 36(9), 604-611. doi:10.1016/j.jmpt.2013.08.004Lobbezoo, F., Visscher, C. M., & Naeije, M. (2004). Impaired health status, sleep disorders, and pain in the craniomandibular and cervical spinal regions. European Journal of Pain, 8(1), 23-30. doi:10.1016/s1090-3801(03)00061-2Lu, X., Wang, Y., Lu, J., You, Y., Zhang, L., Zhu, D., & Yao, F. (2018). Does vibration benefit delayed-onset muscle soreness?: a meta-analysis and systematic review. Journal of International Medical Research, 47(1), 3-18. doi:10.1177/0300060518814999Lucas, K. R., Polus, B. I., & Rich, P. A. (2004). Latent myofascial trigger points: their effects on muscle activation and movement efficiency. Journal of Bodywork and Movement Therapies, 8(3), 160-166. doi:10.1016/j.jbmt.2003.12.002Lundeberg, T., Nordemar, R., & Ottoson, D. (1984). Pain alleviation by vibratory stimulation. Pain, 20(1), 25-44. doi:10.1016/0304-3959(84)90808-xMacDermid, J. C., Walton, D. M., Avery, S., Blanchard, A., Etruw, E., McAlpine, C., & Goldsmith, C. H. (2009). Measurement Properties of the Neck Disability Index: A Systematic Review. Journal of Orthopaedic & Sports Physical Therapy, 39(5), 400-C12. doi:10.2519/jospt.2009.2930Mansilla-Ferragut, P., Fernández-de-las Peñas, C., Alburquerque-Sendín, F., Cleland, J. A., & Boscá-Gandía, J. J. (2009). Immediate Effects of Atlanto-Occipital Joint Manipulation on Active Mouth Opening and Pressure Pain Sensitivity in Women With Mechanical Neck Pain. Journal of Manipulative and Physiological Therapeutics, 32(2), 101-106. doi:10.1016/j.jmpt.2008.12.003Melzack, R., & Wall, P. D. (1965). Pain Mechanisms: A New Theory. 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    Rosetas en el quiste tricolémico proliferante: una nueva observación dermatoscópica

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    Las rosetas son un hallazgo dermatoscópico perteneciente algrupo de las estructuras blancas brillantes. Fueron descritas porprimera vez en 20091ysedefinencomo4puntosblancosbrillantes agrupados como un trébol de 4 hojas o terrones de 4puntos organizados en un cuadrado correspondiente a laapertura folicular2. Se observan exclusivamente condermatoscopia de luz polarizada, con o sin contacto3.Aunqueinicialmente se pensó que eran específicas de las queratosisactínicas y el carcinoma de células escamosas1, posteriormentese han descrito en muchas otras lesiones como el carcinomabasocelular, el melanoma, la piel con daño actínico, lasqueratosis seborreicas planas3, el tricoepitelioma múltiplefamiliar4, la queratosis liquenoide benigna5y enfermedadesinflamatorias y autoinmunitarias como el granuloma anular6oel lupus eritematoso discoide7. Presentamos un caso con rosetasen una lesión previamente no descrita. Varón de 74 años, sin antecedentes patológicos de interés, consultó por una lesión asintomática en cuero cabelludo, decrecimiento lento y varios años de evolución. En la exploración, presentaba una lesión nodular aislada, rosada, cupuliforme, de10 mm de diámetro en región interparietal del cuero cabelludo(fig. 1). Con el dermatoscopio de luz polarizada (Dermlite DL200HR), se observaba una lesión eritematosa, con vasos lineales yarboriformes mal enfocados de distinto calibre, y áreas centralesblanco-amarillentas entre las que se apreciaban varias rosetas(fig. 2). Ante el diagnóstico diferencial de quiste tricolémico, ..

    Intracellular calcium movements of boar spermatozoa during 'in vitro' capacitation and subsequent acrosome exocytosis follow a multiple-storage place, extracellular calcium-dependent model

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    This work analysed intracellular calcium stores of boar spermatozoa subjected to invitro' capacitation (IVC) and subsequent progesterone-induced acrosome exocytosis (IVAE). Intracellular calcium was analysed through two calcium markers with different physico-chemical properties, Fluo-3 and Rhod-5N. Indicative parameters of IVC and IVAE were also evaluated. Fluo-3 was located at both the midpiece and the whole head. Rhod-5N was present at the sperm head. This distribution did not change in any of the assayed conditions. Induction of IVC was concomitant with an increase in both head and midpiece Ca2+ signals. Additionally, while IVC induction was concurrent with a significant (p<0.05) increase in sperm membrane permeability, no significant changes were observed in O-2 consumption and ATP levels. Incubation of boar spermatozoa in the absence of calcium showed a loss of both Ca2+ labellings concomitantly with the sperm's inability to achieve IVC. The absence of extracellular calcium also induced a severe decrease in the percentage of spermatozoa exhibiting high mitochondrial membrane potential (hMMP). The IVAE was accompanied by a fast increase in both Ca2+ signalling in control spermatozoa. These peaks were either not detected or much lessened in the absence of calcium. Remarkably, Fluo-3 marking at the midpiece increased after progesterone addition to sperm cells incubated in a medium without Ca2+. The simultaneous addition of progesterone with the calcium chelant EGTA inhibited IVAE, and this was accompanied by a significant (p<0.05) decrease in the intensity of progesterone Ca2+-induced peak, O-2 consumption and ATP levels. Our results suggest that boar spermatozoa present different calcium deposits with a dynamic equilibrium among them and with the extracellular environment. Additionally, the modulation role of the intracellular calcium in spermatozoa function seems to rely on its precise localization in boar spermatozoa

    'In vitro' capacitation and acrosome reaction are concomitant with specific changes in mitochondrial activity in boar sperm: evidence for a nucleated mitochondrial activation and for the existence of a capacitation-sensitive subpopulational structure

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    The main scope of this manuscript is to analyse the dynamics of mitochondrial activity in boar sperm subjected to 'in vitro' capacitation (IVC) and subsequent progesterone-induced 'in vitro' acrosome reaction (IVAR). This was determined after analysis of the rhythm of O(2) consumption and concomitant changes in the mitochondria activity-specific JC-1 staining. Results showed that IVC, and especially IVAR, was concomitant with a peak in O(2) consumption (from 1.61 ± 0.08 nmol O(2)/min/10(7) viable sperm at 0 h of incubation to 2.62 ± 0.12 nmol O(2) /min/10(7) viable sperm after 5 min of IVAR induction). These results were accompanied by parallel changes in the mean intensity of JC-1 staining. Based on JC-1, mitochondrial activation followed a nucleated pattern, with specific, activation starting points at the midpiece from which mitochondrial activation was spread. Moreover, four separate sperm subpopulations were detected following the JC-1 orange-red/green ratio, and the observed changes in the mean JC-1 staining during IVC and IVAR were related to concomitant changes in both the orange-red/green JC-1 ratio and the percentage of sperm included in each subpopulation. All of these results indicate that IVC and the first minutes of IVAR are accompanied by a progressive increase in mitochondrial activity, which reached a peak coincidental with the achievement of IVAR. Moreover, results suggest the presence of separate sperm subpopulations, which show a different mitochondrial sensitivity to IVC and IVAR. Finally, mitochondrial activation, at least under JC-1 staining, seems to originate in concrete nucleation points at the midpiece, thus suggesting thus a well-coordinated pattern in boar-sperm mitochondrial activity modulation

    Hypotrichosis simplex of the scalp and peeling skin disease, two sides of the same coin

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    Corneodesmosin (CDSN) is a keratinocyte adhesion glycoprotein located in the extracellular domain of corneodesmosomes and in the inner root sheath of the hair follicles.1 Both mono-allelic and bi-allelic pathogenic variants in the CDSN gene have been shown to produce distinctive dermatological conditions. Here, we present two paediatric cases illustrating the wide clinical spectrum of CDSN anomalies
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