Giant megacolon caused by anterior displacement of the anus in a 71-year-old woman

The patient was a 71-year-old woman who was referred to the general surgery clinic due to a severe colonic dilatation and a fecal mass that was found in her abdominopelvic CT scan, which was ordered by a nephrologist for approaching her right flank pain. The patient had experienced bloating and progressive abdominal distension in the year prior to the current visit. The last defecation had occurred approximately 20 days prior to the visit, and the last gas passage had occurred the day before the visit.&nbsp

An Improved Big Bang-Big Crunch Algorithm for Estimating Three-Phase Induction Motors Efficiency

Nowadays, the most generated electrical energy is consumed by three-phase induction motors. Thus, in order to carry out preventive measurements and maintenances and eventually employing high-efficiency motors, the efficiency evaluation of induction motors is vital. In this paper, a novel and efficient method based on Improved Big Bang-Big Crunch (I-BB-BC) Algorithm is presented for efficiency estimation in the induction motors. In order to estimate the induction motor’s efficiency, the measured current, the power factor and the input power are applied to the proposed method and an appropriate objective function is presented. The main advantage of the proposed method is efficiency evaluation of induction motor without any intrusive test. Moreover, a new effective and improved version of BB-BC algorithm is introduced. The presented modifications can improve the accuracy and speed of the classic version of algorithm. In order to demonstrate the capabilities of the proposed method, a comparison with other traditional methods and intelligent optimization algorithms is performed

Compuestos útiles para el tratamiento de infecciones bacterianas, composiciones farmaceúticas que los contienen, procedimiento de identificación de los mismos y sus aplicaciones

La presente invención describe una serie de compuestos útiles para reducir o anular procesos determinantes de la patogenicidad y virulencia bacterianas y de la adherencia bacteriana a superficies inertes o células tales como la producción de adhesinas, la motilidad flagelar y la formación de EPSs y biofilms bacterianos. Estos compuestos pueden usarse para la elaboración de composiciones farmacéuticas antibacterianas o de composiciones antisépticas para el tratamiento de un amplio abanico de infecciones bacterianas, como por ejemplo, E. coli, S. typhi, S. dysenteteriae, V. chlolerae, P. aeruginosa, H. pylori, L. monocytogenes, C. difficile y S. pyogenes. Además, se describe un procedimiento para la identificación de dichos compuestosPeer reviewedConsejo Superior de Investigaciones Científicas, Universidad Pública de NavarraA2 Solicitud de patente sin informe sobre el estado de la técnic

Spontaneous suppressor mutations can compensate the total absence of SpoT in Escherichia coli

Póster presentado en el XXIII Congreso Nacional de Microbiología (SEM), celebrado en Salamanca del 11 al 14 de julio de 2011.Peer Reviewe

GlgS, previously described as a glycogen synthesis control protein, is a major negative regulator of flagellar synthesis and motility, type 1 fimbriae adhesins and biofilm polysaccharides production in Escherichia coli

Trabajo presentado en la 9th Warsaw International Medical Congress for Young Scientists (WIMC), celebrada en Varsovia del 9 al 12 de mayo de 2013.Peer Reviewe

GlgS, previously described as a glycogen synthesis control protein, negatively regulates motility and biofilm formation in Escherichia coli

Trabajo presentado en el XXIV Congreso de Microbiología SEM (Sociedad Española de Microbiología), celebrado en L´Hospitalet del 10 al 13 de julio de 2013.Peer Reviewe

Retail Trade Analysis Report, Fiscal Year 2015: Emmet County

This report examines local retail sales and related economic trends in Emmet County, Iowa, using a variety of comparative performance measures. The retail analysis is based on state-reported sales of goods and services that are subject to Iowa’s statewide sales tax. Please refer to the Data Notes section for detailed information about the types of retail activity included in taxable sales. The data notes also include definitions and guidelines for interpreting retail measures and other indicators in this report. Except where otherwise noted, retail sales data for preceding years have been adjusted for inflation and are stated in Fiscal Year 2015 dollar equivalents. The 2015 fiscal year began on July 1, 2014, and ended on June 30, 2015

Systematic Production of Inactivating and NonInactivating Suppressor Mutations at the relA Locus That Compensate the Detrimental Effects of Complete spoT Loss and Affect Glycogen Content in Escherichia coli

In Escherichia coli, ppGpp is a major determinant of growth and glycogen accumulation. Levels of this signaling nucleotide are controlled by the balanced activities of the ppGpp RelA synthetase and the dual-function hydrolase/synthetase SpoT. Here we report the construction of spoT null (DspoT) mutants obtained by transducing a DspoT allele from DrelADspoT double mutants into relA+ cells. Iodine staining of randomly selected transductants cultured on a rich complex medium revealed differences in glycogen content among them. Sequence and biochemical analyses of 8 DspoT clones displaying glycogen-deficient phenotypes revealed different inactivating mutations in relA and no detectable ppGpp when cells were cultured on a rich complex medium. Remarkably, although the co-existence of DspoT with relA proficient alleles has generally been considered synthetically lethal, we found that 11 DspoT clones displaying high glycogen phenotypes possessed relA mutant alleles with non-inactivating mutations that encoded stable RelA proteins and ppGpp contents reaching 45–85% of those of wild type cells. None of the DspoT clones, however, could grow on M9-glucose minimal medium. Both Sanger sequencing of specific genes and high-throughput genome sequencing of the DspoT clones revealed that suppressor mutations were restricted to the relA locus. The overall results (a) defined in around 4 nmoles ppGpp/g dry weight the threshold cellular levels that suffice to trigger net glycogen accumulation, (b) showed that mutations in relA, but not necessarily inactivating mutations, can be selected to compensate total SpoT function(s) loss, and (c) provided useful tools for studies of the in vivo regulation of E. coli RelA ppGpp synthetaseFil: Montero, Manuel. Gobierno de Navarra. Instituto de Agrobiotecnología; EspañaFil: Rahimpour, Mehdi. Gobierno de Navarra. Instituto de Agrobiotecnología; EspañaFil: Viale, Alejandro Miguel. Gobierno de Navarra. Instituto de Agrobiotecnología; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Almagro, Goizeder. Gobierno de Navarra. Instituto de Agrobiotecnología; EspañaFil: Eydallin, Gustavo. Gobierno de Navarra. Instituto de Agrobiotecnología; EspañaFil: Sevilla, Angel. Universidad de Murcia; EspañaFil: Canovas, Manuel. Universidad de Murcia; EspañaFil: Bernal, Cristina. Universidad de Murcia; EspañaFil: Lozano, Ana Belen. Universidad de Murcia; EspañaFil: Muñoz, Francisco Jose. Gobierno de Navarra. Instituto de Agrobiotecnología; EspañaFil: Bora Fernandez, Edurne. Gobierno de Navarra. Instituto de Agrobiotecnología; EspañaFil: Bahaji, Abdellatif. Gobierno de Navarra. Instituto de Agrobiotecnología; EspañaFil: Mori, Hirotada. Nara Institute of Science and Technology. Graduate School of Biological Sciences; JapónFil: Codoñer, Francisco M.. Lifesequencing SL. Valencia; EspañaFil: Potueza Romeo, Javier. Gobierno de Navarra. Instituto de Agrobiotecnología; Españ

Epididimitis ovina: Brucella ovis

Brucella ovis es una enfermedad que causa epididimitis, orquitis y disminución de la fertilidad en los carneros, con pérdidas económicas considerables. Se han informado síntomas similares en venados macho en Nueva Zelanda. Ocasionalmente, B. ovis se asocia con abortos en las ovejas, y puede causar un aumento en la mortalidad perinatal de los corderos

Regulation of Escherichia coli glycogen metabolism by GlgS and SpoT

Peer Reviewe