The Tabby cat locus maps to feline chromosome B1.

The Tabby markings of the domestic cat are unique coat patterns for which no causative candidate gene has been inferred from other mammals. In this study, a genome scan was performed on a large pedigree of cats that segregated for Tabby coat markings, specifically for the Abyssinian (Ta-) and blotched (tbtb) phenotypes. There was linkage between the Tabby locus and eight markers on cat chromosome B1. The most significant linkage was between marker FCA700 and Tabby (Z = 7.56, theta = 0.03). Two additional markers in the region supported linkage, although not with significant LOD scores. Pairwise analysis of the markers supported the published genetic map of the cat, although additional meioses are required to refine the region. The linked markers cover a 17-cM region and flank an evolutionary breakpoint, suggesting that the Tabby gene has a homologue on either human chromosome 4 or 8. Alternatively, Tabby could be a unique locus in cats

Prolapsus Gravidique: Facteurs de Risque, Complications et Prise en Charge en Afrique Sub-Saharienne

Objectif :  Le but de cette étude était d’aborder les caractéristiques socio démographie, les aspects thérapeutiques et le pronostic du prolapsus utérin extériorisé survenu pour la première fois pendant la grossesse. Patientes et Méthodes : Il s’agissait d’une étude prospective sur une période de 12 mois (1er janvier au 31 décembre 2021) portant sur les patientes prise en charge pour prolapsus gestationnel. Résultats: Sept cas ont été enregistrés durant la période d’étude. La fréquence du prolapsus gestationnel était de 2 cas/1000 accouchements dans notre service. Les patientes étaient jeunes (28-31 ans), multipares avec un âge moyen de 28,57 ans et une parité moyenne de quatre enfants. Elles étaient très jeunes à leurs premier accouchement (16-20 ans). La plupart de facteurs de risques décrits dans la littérature étaient retrouvés chez nos patientes. La rupture prématurée des membranes (2 cas, 28,57%), la chorioamniotite (1 cas, 14,28%), l’accouchement prématuré (1 cas, 14,28%), l’hémorragie de la délivrance (1 cas, 14,28%) et l’anémie (1 cas, 14,28%) ont été les complications retrouvées. Un traitement conservateur a été réalisé chez toutes les patientes (100%). L’évolution était favorable avec une régression spontanée du prolapsus dans le post-partum immédiat chez toutes nos patientes (100%). Après six mois de suivi, les prolapsus n´ont pas récidivés. Conclusion : Le prolapsus gestationnel n’est pas exceptionnel dans notre contexte. Malgré son caractère angoissant pour la patiente, sa famille et l’équipe obstétricale, une attitude conservatrice peut se discuter devant un prolapsus apparu pour la première fois au cours de la grossesse chez une patiente jeune sans antécédents pathologiques particuliers.   Objective : The aim of this study was to address the socio-demographic characteristics, therapeutic aspects and prognosis of externalized uterine prolapse occurring for the first time during pregnancy. Patients and Methods : This was a prospective study over a period of 12 months (January 1 to December 31, 2021) focusing on patients treated for gravidarum prolapse. Results : Seven cases were recorded during the study period. The frequency of gravidarum prolapse was 2 cases/1000 deliveries in our department. The patients were young (28-31 years old), multiparous with an average age of 28.57 years and an average parity of four children. They were very young when they first gave birth (16-20 years old). Most of the risk factors described in the literature were found in our patients. Premature rupture of membranes (2 cases, 28.57%), chorioamnionitis (1 case, 14.28%), premature delivery (1 case, 14.28%), postpartum hemorrhage (1 case, 14.28%) and anemia (1 case, 14.28%) were the complications found. Conservative treatment was carried out in all patients (100%). The evolution was favorable with spontaneous regression of the prolapse in the immediate postpartum period in all our patients (100%). After six months of follow-up, the prolapses have not recurred. Conclusion : gravidarum prolapse is not exceptional in our context. Despite its distressing nature for the patient, her family and the obstetric team, a conservative attitude can be questioned when faced with a prolapse appearing for the first time during pregnancy in a young patient without any particular pathological history

UNIFIED TOPOLOGICAL FRAMEWORK FOR RETRIEVING 2D AND 3D MULTI-SCALE SPATIAL INFORMATION

Different applications or users need different model (differ requirement on level of details; geometry and information), less focuses in topological element. Improper manage geometry, attribute and topology elements in multi-scape environment will cause data repetition/redundancy, storage capacity and performance issues. This research focuses on utilizing topological graph which is important for various Geographical Information Science applications such as 3D indoor, network analysis, and sharing information/attribute from multiple level of details (LoD). A conceptual framework towards a unified data structure/model for representing several levels of details (LoDs) which integrates 2D and 3D topological and geometrical spaces in a single view is presented. The proposed framework has a potential of adopting into the CityGML/IndoorGML standards with representing different CityGML LoDs in a single view representation. Potential applications of the proposed conceptual framework including solar energy and utility mapping are discussed

Transport properties of dense fluid argon

We calculate using molecular dynamics simulations the transport properties of realistically modeled fluid argon at pressures up to $\simeq 50GPa$ and temperatures up to $3000K$. In this context we provide a critique of some newer theoretical predictions for the diffusion coefficients of liquids and a discussion of the Enskog theory relevance under two different adaptations: modified Enskog theory (MET) and effective diameter Enskog theory. We also analyze a number of experimental data for the thermal conductivity of monoatomic and small diatomic dense fluids.Comment: 8 pages, 6 figure

Diffusion Time-Scale Invariance, Markovization Processes and Memory Effects in Lennard-Jones Liquids

We report the results of calculation of diffusion coefficients for Lennard-Jones liquids, based on the idea of time-scale invariance of relaxation processes in liquids. The results were compared with the molecular dynamics data for Lennard-Jones system and a good agreement of our theory with these data over a wide range of densities and temperatures was obtained. By calculations of the non-Markovity parameter we have estimated numerically statistical memory effects of diffusion in detail.Comment: 10 pages, 3 figure

Relationship of homestead food production with night blindness among children below 5 years of age in Bangladesh

Abstract Objective To examine the relationship between homestead food production and night blindness among pre-school children in rural Bangladesh in the presence of a national vitamin A supplementation programme. Design A cross-sectional study. Setting A population-based sample of six rural divisions of Bangladesh assessed in the Bangladesh Nutrition Surveillance Project 2001-2005. Subjects A total of 158 898 children aged 12-59 months. Results The prevalence rates of night blindness in children among those who did and did not receive vitamin A capsules in the last 6 months were 0·07 % and 0·13 %, respectively. Given the known effect of vitamin A supplementation on night blindness, the analysis was stratified by children's receipt of vitamin A capsules in the last 6 months. Among children who did not receive vitamin A capsules in the last 6 months, the lack of a home garden was associated with increased odds of night blindness (OR = 3·16, 95 % CI 1·76, 5·68; P = 0·0001). Among children who received vitamin A capsules in the last 6 months, the lack of a home garden was not associated with night blindness (OR = 1·28, 95 % CI 0·71, 2·31; P = 0·4). Conclusions Homestead food production confers a protective effect against night blindness among pre-school children who missed vitamin A supplementation in rural Banglades

Reading Scepticism Historically. Scepticism, Acatalepsia and the Fall of Adam in Francis Bacon

The first part of this paper will provide a reconstruction of Francis Bacon’s interpretation of Academic scepticism, Pyrrhonism, and Dogmatism, and its sources throughout his large corpus. It shall also analyze Bacon’s approach against the background of his intellectual milieu, looking particularly at Renaissance readings of scepticism as developed by Guillaume Salluste du Bartas, Pierre de la Primaudaye, Fulke Greville, and John Davies. It shall show that although Bacon made more references to Academic than to Pyrrhonian Scepticism, like most of his contemporaries, he often misrepresented and mixed the doctrinal components of both currents. The second part of the paper shall offer a complete chronological survey of Bacon’s assessment of scepticism throughout his writings. Following the lead of previous studies by other scholars, I shall support the view that, while he approved of the state of doubt and the suspension of judgment as a provisional necessary stage in the pursuit of knowledge, he rejected the notion of acatalepsia. To this received reading, I shall add the suggestion that Bacon’s criticism of acatalepsia ultimately depends on his view of the historical conditions that surround human nature. I deal with this last point in the third part of the paper, where I shall argue that Bacon’s evaluation of scepticism relied on his adoption of a Protestant and Augustinian view of human nature that informed his overall interpretation of the history of humanity and nature, including the sceptical schools