Age and menarcheal status do not influence metabolic response to aerobic training in overweight girls

BACKGROUND: Multidisciplinary intervention is an alternative for the treatment of children and adolescent obese. However, the influence of age and menarcheal status in the pattern of metabolic response of obese girls has not been investigated. The following study examined the effects of a 12-week multidisciplinary intervention on metabolic health in overweight girls and the contribution of age and menarcheal status on the resulting changes. METHODS: Eighty-eight overweight girls (10 - 16 years) were considered initially for this study and randomly assigned (intervention group: n = 58; control group: n = 30). Forty-six girls completed the intervention program and 16 girls completed the follow-up for the control group. The 12-week intervention included aerobic exercises (three times per week) and nutritional intervention. Anthropometrical measures (body mass, body mass index and waist circumference), menarcheal status and metabolic profiles including glucose, insulin, triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were assessed in the beginning and after of intervention. Additionally, were calculated homeostatic model assessment-insulin resistance (HOMA-IR) and quantitative insulin sensitivity check index (QUICKI). RESULTS: After 12-week, girls decreased significantly the body mass (76.6 ± 14.7 to 75.7 ± 14.6 kg) body mass index (30.1 ± 4.0 to 29.4 ± 4.0 kg/m(2)) and waist circumference (98.9 ± 10.9 to 96.5 ± 11.4 cm). There were differences in HDL-C (43.1 ± 8.2 to 50.3 ± 9.4 mg/dl), TG (120.9 ± 64.3 to 93.3 ± 47.9 mg/dl) and insulin (16.9 ± 7.6 to 15.6 ± 9.8 mg/dl). Relative contribution of age was significant only for within-subject variability in waist circumference. CONCLUSIONS: The multidisciplinary based on aerobic training intervention used in this study produced substantial benefits on metabolic health indicators in overweight girls. The changes observed were not related to inter-individual variability in age and maturity status

Association between adiposity indicators, metabolic parameters and inflammatory markers in a sample of female adolescents

The aim of this study was to investigate the association between total and abdominal adiposity with metabolic parameters and inflammatory markers, in female adolescents. The sample consisted of 53 adolescents aged 13 to 17 years from a public school in Curitiba, Brazil. The adiposity indicators studied were body mass index (BMI), waist circumference (WC), trunk fat mass (TKFM), total fat mass (TFM) and body fat percentage (BF%) measured by dual-energy X-ray absorptiometry. The metabolic and inflammatory parameters studied were systolic blood pressure (SBP), diastolic blood pressure (DBP), glucose, insulin, homeostasis model assessment index for insulin resistance (HOMA-IR), lipids, C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), leptin, adiponectin and resistin. Eighty percent of WC variation, 87% of TKFM and TFM, and 73% of BF% were predicted by BMI variation. There was a significant positive correlation between all indicators of adiposity with SBP, DBP, insulin, HOMA-IR, CRP and leptin. Triglycerides were positively correlated with BMI and WC, and adiponectin correlated negatively with BMI. TNF-α, IL-6, glucose, total cholesterol, and high- and low-density lipoprotein cholesterol did not correlate to the studied variables. BMI showed a significant association with most of the parameters studied, and WC was slightly better than BMI to predict insulin resistance in this specific population.59432533

O complexo cultural e o complexo do comer: um estudo com mulheres obesas

Obesity is considered an epidemic problem, which causes serious damage to the physical and emotional health of individuals. In order to investigate the psychological and cultural phenomena involved in obesity, we propouse a comprehensive and symbolic view of the discourses of obese women, patients from a General Hospital in Curitiba-Pr. The study was based on theoretical constructs such as: Jung's Complex Theory, Henderson's Cultural Unconscious, Singer and Kimbles' Cultural Complex. From these theories, it is aimed to propose a new theoretical construct: the Eating Complex, which is represented by experiences related to the theme of food, and relate it to the Cultural Complex. It is observed from the discourses that both Complexes paradoxically express themselves in a way to incorporate unconscious ideas of an ideal body, that rests in an archetypal image of hunger and lack. In a context of health, this lack marks the need for a filling that is often excessive and denatured, which should be considered in the multidisciplinary treatment of obesity, through therapeutic strategies that contemplate this reality and the vision of psyche totality.A obesidade é considerada um problema epidêmico, que acarreta graves prejuízos na saúde física e emocional dos indivíduos. Em busca de investigar os fenômenos psicológicos e culturais envolvidos na obesidade, propõe-se uma visão compreensiva-simbólica dos discursos de mulheres obesas pacientes de um Hospital Geral em Curitiba-Pr. O estudo baseou-se em constructos teóricos como: a Teoria dos Complexos para Jung, o Inconsciente Cultural para Henderson, o Complexo Cultural para Singer e Kimbles. A partir desses visa-se propor um novo constructo teórico: o Complexo do Comer, que é representado pelas experiências vinculadas ao tema alimentação, e relacioná-lo com o Complexo Cultural. Observa-se, a partir dos discursos, que ambos os Complexos expressam-se, paradoxalmente, a forma de incorporar ideias inconscientes de um corpo ideal, que repousam em uma imagem arquetípica da fome e da falta. Num contexto da saúde, esta falta marca a necessidade de um preencher que muitas vezes se faz excessivo e desnaturado, a qual deve ser considerada no tratamento multidisciplinar da obesidade, por meio de estratégias terapêuticas que contemplem essa realidade e a visão de totalidade psíquica.La obesidad es considerada un problema epidémico, que acarrea graves perjuicios en la salud física y emocional de los individuos. En busca de investigar los fenómenos psicológicos y culturales involucrados en la obesidad, se propone una visión comprensiva-simbólica de los discursos de mujeres obesas pacientes de un Hospital General en Curitiba-Pr. El estudio se basó en constructos teóricos como: la Teoría de los Complejos para Jung, el Inconsciente Cultural para Henderson, el Complejo Cultural para Singer y Kimbles. A partir de estos se pretende proponer un nuevo constructo teórico: el Complejo del Comer, que es representado por las experiencias vinculadas al tema alimentación, y relacionarlo con el Complejo Cultural. Se observa, a partir de los discursos, que ambos Complejos se expresan paradójicamente la forma de incorporar ideas inconscientes de un cuerpo ideal, que reposan en una imagen arquetípica del hambre y de la falta. En un contexto de la salud, esta falta marca la necesidad de un relleno que muchas veces se hace excesivo y desnaturalizado, la cual debe ser considerada en el tratamiento multidisciplinario de la obesidad, a través de estrategias terapéuticas que contemplen esa realidad y la visión de totalidad psíquica

Peak oxygen uptake responses to training in obese adolescents: a multilevel allometric framework to partition the influence of body size and maturity status

The influence of body size and maturation on the responses in peak oxygen uptake (VO2) to a 12-week aerobic training and nutritional intervention in obese boys (n = 30; 10-16 years) was examined using multilevel allometric regressions. Anthropometry, sexual maturity status, peak VO2, and body composition were measured pre- and postintervention. Significant decrements for body mass, body mass index z-score, and waist circumference and increments for stature, fat-free mass, and peak oxygen uptake were observed after intervention. Partitioning body size on peak VO2, the responses of the individuals to training were positive (11.8% to 12.7% for body mass; 7.6% to 8.1% for fat-free mass). Body mass and fat-free mass were found as significant explanatory variables, with an additional positive effect for chronological. The allometric coefficients (k') in the initial models were k' = 0.883 and k' = 1.058 for body mass and fat-free mass, respectively. The coefficients decreased when age was considered (k' = 0.530 for body mass; k' = 0.860 for fat-free mass). Including maturity indicator in the models was not significant, thus the influence of variability in sexual maturity status in responses to exercise-based intervention in peak VO2 may be mediated by the changes in body dimensions

Age and menarcheal status do not influence metabolic response to aerobic training in overweight girls

Abstract Background Multidisciplinary intervention is an alternative for the treatment of children and adolescent obese. However, the influence of age and menarcheal status in the pattern of metabolic response of obese girls has not been investigated. The following study examined the effects of a 12-week multidisciplinary intervention on metabolic health in overweight girls and the contribution of age and menarcheal status on the resulting changes. Methods Eighty-eight overweight girls (10 - 16 years) were considered initially for this study and randomly assigned (intervention group: n = 58; control group: n = 30). Forty-six girls completed the intervention program and 16 girls completed the follow-up for the control group. The 12-week intervention included aerobic exercises (three times per week) and nutritional intervention. Anthropometrical measures (body mass, body mass index and waist circumference), menarcheal status and metabolic profiles including glucose, insulin, triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were assessed in the beginning and after of intervention. Additionally, were calculated homeostatic model assessment-insulin resistance (HOMA-IR) and quantitative insulin sensitivity check index (QUICKI). Results After 12-week, girls decreased significantly the body mass (76.6 ± 14.7 to 75.7 ± 14.6 kg) body mass index (30.1 ± 4.0 to 29.4 ± 4.0 kg/m2) and waist circumference (98.9 ± 10.9 to 96.5 ± 11.4 cm). There were differences in HDL-C (43.1 ± 8.2 to 50.3 ± 9.4 mg/dl), TG (120.9 ± 64.3 to 93.3 ± 47.9 mg/dl) and insulin (16.9 ± 7.6 to 15.6 ± 9.8 mg/dl). Relative contribution of age was significant only for within-subject variability in waist circumference. Conclusions The multidisciplinary based on aerobic training intervention used in this study produced substantial benefits on metabolic health indicators in overweight girls. The changes observed were not related to inter-individual variability in age and maturity status.</p

Association Between Adiposity Indicators, Metabolic Parameters And Inflammatory Markers In A Sample Of Female Adolescents.

The aim of this study was to investigate the association between total and abdominal adiposity with metabolic parameters and inflammatory markers, in female adolescents. The sample consisted of 53 adolescents aged 13 to 17 years from a public school in Curitiba, Brazil. The adiposity indicators studied were body mass index (BMI), waist circumference (WC), trunk fat mass (TKFM), total fat mass (TFM) and body fat percentage (BF%) measured by dual-energy X-ray absorptiometry. The metabolic and inflammatory parameters studied were systolic blood pressure (SBP), diastolic blood pressure (DBP), glucose, insulin, homeostasis model assessment index for insulin resistance (HOMA-IR), lipids, C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), leptin, adiponectin and resistin. Eighty percent of WC variation, 87% of TKFM and TFM, and 73% of BF% were predicted by BMI variation. There was a significant positive correlation between all indicators of adiposity with SBP, DBP, insulin, HOMA-IR, CRP and leptin. Triglycerides were positively correlated with BMI and WC, and adiponectin correlated negatively with BMI. TNF-α, IL-6, glucose, total cholesterol, and high- and low-density lipoprotein cholesterol did not correlate to the studied variables. BMI showed a significant association with most of the parameters studied, and WC was slightly better than BMI to predict insulin resistance in this specific population.59325-33

Association between adiposity indicators, metabolic parameters and inflammatory markers in a sample of female adolescents

Objective The aim of this study was to investigate the association between total and abdominal adiposity with metabolic parameters and inflammatory markers, in female adolescents.Subjects and methods The sample consisted of 53 adolescents aged 13 to 17 years from a public school in Curitiba, Brazil. The adiposity indicators studied were body mass index (BMI), waist circumference (WC), trunk fat mass (TKFM), total fat mass (TFM) and body fat percentage (BF%) measured by dual-energy X-ray absorptiometry. The metabolic and inflammatory parameters studied were systolic blood pressure (SBP), diastolic blood pressure (DBP), glucose, insulin, homeostasis model assessment index for insulin resistance (HOMA-IR), lipids, C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), leptin, adiponectin and resistin.Results Eighty percent of WC variation, 87% of TKFM and TFM, and 73% of BF% were predicted by BMI variation. There was a significant positive correlation between all indicators of adiposity with SBP, DBP, insulin, HOMA-IR, CRP and leptin. Triglycerides were positively correlated with BMI and WC, and adiponectin correlated negatively with BMI. TNF-α, IL-6, glucose, total cholesterol, and high- and low-density lipoprotein cholesterol did not correlate to the studied variables.Conclusion BMI showed a significant association with most of the parameters studied, and WC was slightly better than BMI to predict insulin resistance in this specific population

Tradução para o português e validação do instrumento Diabetes Quality of Life Measure (DQOL-Brasil)

Objetivo: Avaliar as propriedades psicométricas da versão brasileira do questionário de medida da qualidade de vida em diabetes (DQOL). Métodos: O DQOL foi traduzido ao português segundo protocolo e aplicado em 121 indivíduos (56,2% mulheres), com tempo diagnóstico médio de diabetes melito tipo 2 de 8,1 ± 7,13 anos e na faixa etária de 32 a 89 anos. Resultados: O instrumento apresentou consistência interna total (α de Cronbach = 0,92). Todas as questões apresentaram correlação positiva (p < 0,01) com seus domínios e com o escore geral do questionário, exceto as questões 18 e 35, que requereram exclusão da versão traduzida. O instrumento foi capaz de diferenciar pacientes com HbA1c acima e abaixo de 9% (p = 0,01). Conclusão: O DQOL-Brasil apresenta aspectos de confiabilidade e validade adequados para sua utilização em pacientes adultos com diabetes tipo 2