2,934 research outputs found
Mitochondrial uncoupling as a regulator of life-history trajectories in birds: an experimental study in the zebra finch.
Mitochondria have a fundamental role in the transduction of energy from food into ATP. The coupling between food oxidation and ATP production is never perfect, but may nevertheless be of evolutionary significance. The 'uncoupling to survive' hypothesis suggests that 'mild' mitochondrial uncoupling evolved as a protective mechanism against the excessive production of damaging reactive oxygen species (ROS). Because resource allocation and ROS production are thought to shape animal life histories, alternative life-history trajectories might be driven by individual variation in the degree of mitochondrial uncoupling. We tested this hypothesis in a small bird species, the zebra finch (Taeniopygia guttata), by treating adults with the artificial mitochondrial uncoupler 2,4-dinitrophenol (DNP) over a 32-month period. In agreement with our expectations, the uncoupling treatment increased metabolic rate. However, we found no evidence that treated birds enjoyed lower oxidative stress levels or greater survival rates, in contrast to previous results in other taxa. In vitro experiments revealed lower sensitivity of ROS production to DNP in mitochondria isolated from skeletal muscles of zebra finch than mouse. In addition, we found significant reductions in the number of eggs laid and in the inflammatory immune response in treated birds. Altogether, our data suggest that the 'uncoupling to survive' hypothesis may not be applicable for zebra finches, presumably because of lower effects of mitochondrial uncoupling on mitochondrial ROS production in birds than in mammals. Nevertheless, mitochondrial uncoupling appeared to be a potential life-history regulator of traits such as fecundity and immunity at adulthood, even with food supplied ad libitum
An open and parallel multiresolution framework using block-based adaptive grids
A numerical approach for solving evolutionary partial differential equations
in two and three space dimensions on block-based adaptive grids is presented.
The numerical discretization is based on high-order, central finite-differences
and explicit time integration. Grid refinement and coarsening are triggered by
multiresolution analysis, i.e. thresholding of wavelet coefficients, which
allow controlling the precision of the adaptive approximation of the solution
with respect to uniform grid computations. The implementation of the scheme is
fully parallel using MPI with a hybrid data structure. Load balancing relies on
space filling curves techniques. Validation tests for 2D advection equations
allow to assess the precision and performance of the developed code.
Computations of the compressible Navier-Stokes equations for a temporally
developing 2D mixing layer illustrate the properties of the code for nonlinear
multi-scale problems. The code is open source
Dissecting the origin of the submillimeter emission in nearby galaxies with Herschel and LABOCA
We model the infrared to submillimeter spectral energy distribution of 11
nearby galaxies of the KINGFISH sample using Spitzer and Herschel data and
compare model extrapolations at 870um (using different fitting techniques) with
LABOCA 870um observations. We investigate how the differences between
predictions and observations vary with model assumptions or environment. At
global scales, we find that modified blackbody models using realistic cold
emissivity indices (beta_c=2 or 1.5) are able to reproduce the 870um observed
emission within the uncertainties for most of the sample. Low values
(beta_c<1.3) would be required in NGC0337, NGC1512 and NGC7793. At local
scales, we observe a systematic 870um excess when using beta_=2.0. The
beta_c=1.5 or the Draine and Li (2007) models can reconcile predictions with
observations in part of the disks. Some of the remaining excesses occur towards
the centres and can be partly or fully accounted for by non-dust contributions
such as CO(3-2) or, to a lesser extent, free-free or synchrotron emission. In
three non-barred galaxies, the remaining excesses rather occur in the disk
outskirts. This could be a sign of a flattening of the submm slope (and
decrease of the effective emissivity index) with radius in these objects.Comment: 31 pages (including appendix), 7 figures, accepted for publication in
MNRA
The secondary eclipses of WASP-19b as seen by the ASTEP 400 telescope from Antarctica
The ASTEP (Antarctica Search for Transiting ExoPlanets) program was
originally aimed at probing the quality of the Dome C, Antarctica for the
discovery and characterization of exoplanets by photometry. In the first year
of operation of the 40 cm ASTEP 400 telescope (austral winter 2010), we
targeted the known transiting planet WASP-19b in order to try to detect its
secondary transits in the visible. This is made possible by the excellent
sub-millimagnitude precision of the binned data. The WASP-19 system was
observed during 24 nights in May 2010. The photometric variability level due to
starspots is about 1.8% (peak-to-peak), in line with the SuperWASP data from
2007 (1.4%) and larger than in 2008 (0.07%). We find a rotation period of
WASP-19 of 10.7 +/- 0.5 days, in agreement with the SuperWASP determination of
10.5 +/- 0.2 days. Theoretical models show that this can only be explained if
tidal dissipation in the star is weak, i.e. the tidal dissipation factor Q'star
> 3.10^7. Separately, we find evidence for a secondary eclipse of depth 390 +/-
190 ppm with a 2.0 sigma significance, a phase consistent with a circular orbit
and a 3% false positive probability. Given the wavelength range of the
observations (420 to 950 nm), the secondary transit depth translates into a day
side brightness temperature of 2690(-220/+150) K, in line with measurements in
the z' and K bands. The day side emission observed in the visible could be due
either to thermal emission of an extremely hot day side with very little
redistribution of heat to the night side, or to direct reflection of stellar
light with a maximum geometrical albedo Ag=0.27 +/- 0.13. We also report a
low-frequency oscillation well in phase at the planet orbital period, but with
a lower-limit amplitude that could not be attributed to the planet phase alone,
and possibly contaminated with residual lightcurve trends.Comment: Accepted for publication in Astronomy and Astrophysics, 13 pages, 13
figure
NIKA2: a mm camera for cluster cosmology
Galaxy clusters constitute a major cosmological probe. However, Planck 2015
results have shown a weak tension between CMB-derived and cluster-derived
cosmological parameters. This tension might be due to poor knowledge of the
cluster mass and observable relationship.
As for now, arcmin resolution Sunyaev-Zeldovich (SZ) observations ({\it e.g.}
SPT, ACT and Planck) only allowed detailed studies of the intra cluster medium
for low redshift clusters () high
resolution and high sensitivity SZ observations are needed. With both a wide
field of view (6.5 arcmin) and a high angular resolution (17.7 and 11.2 arcsec
at 150 and 260 GHz), the NIKA2 camera installed at the IRAM 30-m telescope
(Pico Veleta, Spain) is particularly well adapted for these observations. The
NIKA2 SZ observation program will map a large sample of clusters (50) at
redshifts between 0.5 and 0.9. As a pilot study for NIKA2, several clusters of
galaxies have been observed with the pathfinder, NIKA, at the IRAM 30-m
telescope to cover the various configurations and observation conditions
expected for NIKA2.
Nika2: A mm camera for cluster cosmology
Galaxy clusters constitute a major cosmological probe. However, Planck 2015 results have shown a weak tension between CMB-derived and cluster-derived cosmological parameters. This tension might be due to poor knowledge of the cluster mass and observable relationship. As for now, arcmin resolution Sunyaev-Zeldovich (SZ) observations (e.g. SPT, ACT and Planck) only allowed detailed studies of the intra cluster medium for low redshift clusters (z 0:5) high resolution and high sensitivity SZ observations are needed. With both a wide field of view (6.5 arcmin) and a high angular resolution (17.7 and 11.2 arcsec at 150 and 260 GHz), the NIKA2 camera installed at the IRAM 30-m telescope (Pico Veleta, Spain) is particularly well adapted for these observations. The NIKA2 SZ observation program will map a large sample of clusters (50) at redshifts between 0.5 and 0.9. As a pilot study for NIKA2, several clusters of galaxies have been observed with the pathfinder, NIKA, at the IRAM 30-m telescope to cover the various configurations and observation conditions expected for NIKA2
Spectroscopy of F
The structure of the weakly-bound F odd-odd nucleus,
produced from Na nuclei, has been investigated at GANIL by means of
the in-beam -ray spectroscopy technique. A single -line is
observed at 657(7) keV in F which has been ascribed to the decay of
the excited J= state to the J=1 ground state. The possible presence of
intruder negative parity states in F is also discussed.Comment: 3 pages, 1 figure, accepted for publication in Physical Review
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