2,933 research outputs found

    Sobre la evolución contemporánea de la teoría de los derechos del hombre

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    L'art pariétal de la grotte Tastet (Sainte-Colome, Pyrénées-Atlantiques) : au carrefour des traditions artistiques tardiglaciaires

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    International audienceSince 2012, Tastet Cave (Sainte-Colome, Pyrénées-Atlantiques) is the subject of a new research program led by one of the authors (J.-M. P.). This program offered the opportunity to restudy the parietal art from this site. The parietal art in Tastet Cave has been known since the 1970s; its restudy by three of the authors (D.G., O.R. and R.B.) offers an updated view of the figures, slightly different from that of the previous publications (Omnès 1983; Blanc and Marsan 1984). In particular, it has been possible to replace this art within the chronological and stylistic framework of the Middle and Upper Magdalenian from the Pyrenean and Cantabrian region.L'ouverture, en 2012, d'une campagne de fouille dirigée par l'un d'entre nous (J.-M. P.) dans la grotte Tastet (Sainte-Colome, Pyrénées-Atlantiques) a fourni l'opportunité d'une nouvelle analyse des parois ornées de cette cavité. La révision de l'art pariétal (menée par D.G., O.R. et R.B.), connu depuis les années 1970, fournit une vision actualisée de l'ensemble orné et quelque peu différente des publications antérieures (Omnès 1983 ; Blanc et Marsan 1984). Cette étude permet notamment de replacer ces manifestations dans un cadre chrono-stylistique qui apparaît être celui du Magdalénien avancé (moyen et supérieur) de la région pyrénéo-cantabrique

    Beads, bubbles and drops in microchannels: stability of centered position and equilibrium velocity

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    Understand and predict the dynamics of dispersed micro-objects in microfluidics is crucial in numerous natural, industrial and technological situations. In this paper, we experimentally characterized the equilibrium velocity VV and lateral position ε\varepsilon of various dispersed micro-objects such as beads, bubbles and drops, in a cylindrical microchannel over an unprecedent wide range of parameters. By systematically varying the dimensionless object size (d[0.1;1]d \in [0.1; 1]), the viscosity ratio (λ[102;[\lambda \in [10^{-2}; \infty[), the density ratio (φ[103;2]\varphi \in [10^{-3}; 2]), the Reynolds number ([102;102]\Re \in [10^{-2}; 10^2]), and the capillary number (Ca[103;0.3]\text{Ca} \in [10^{-3}; 0.3]), we offer a general study exploring various dynamics from the nonderformable viscous regime to the deformable visco-inertio-capillary regime, thus enabling to highlight the sole and combined roles of inertia and capillary effects on lateral migration. The experiments are compared and well-agree with a steady 3D Navier-Stokes model for incompressible two-phase fluids including both the effects of inertia and possible interfacial deformations. This model enables to rationalize the experiments and to provide an exhaustive parametric analysis on the influence of the main parameters of the problem, mainly on two aspects: the stability of the centered position and the velocity of the dispersed object. Interestingly, we propose a useful correlation for the object velocity VV as functions of the dd, ε\varepsilon and λ\lambda, obtained in the Re=Ca=0\text{Re}=\text{Ca}=0 limit, but actually valid for a larger range of values of Re\text{Re} and Ca\text{Ca} in the linear regimes.Comment: 22 pages, 11 figures, submitted to Journal of Fluid Mechanic

    Sensitivity analysis of the hydrological and hydraulic parameters of the SWMM model and its application in urban drainage systems

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    Simulation models are widely used for the design and management of urban drainage systems, such as the SWMM Stormwater Management Model. However, the quality of its results is directly related to the quality of the data provided, since an incorrect estimate of these may lead to a different behavior than expected in the real case. There is uncertainty in many hydrological and hydraulic input parameters of the model, since most of them are estimated and there are no measured data to calibrate it. In this work a sensitivity analysis is carried out to various parameters to detect the most influential in the simulation of urban drainage systems. It consisted of locally varying each of the parameters and assessing their influence on the variation of the flows and maximum levels at a point in the Copacoa Urbanization, Palavecino municipality of the Lara State, Venezuela. From the results obtained, it is concluded that for simulations of urban watersheds where impervious areas predominate, the least sensitive method for the generation of the rain hietrogram is that of alternate blocks, while the one with the greatest variability is the triangular hietrogram. Regarding the basin component, the most sensitive parameters are the percentage of impermeable area, the slope of the basin and the Manning coefficient assigned to the impermeable area. In relation to the duct, the Manning coefficient parameter also presented an appreciable sensitivity, but of a lesser magnitude compared to those obtained for the basin component

    SCOTCH and SODA: A Transformer Video Shadow Detection Framework

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    Shadows in videos are difficult to detect because of the large shadow deformation between frames. In this work, we argue that accounting for shadow deformation is essential when designing a video shadow detection method. To this end, we introduce the shadow deformation attention trajectory (SODA), a new type of video self-attention module, specially designed to handle the large shadow deformations in videos. Moreover, we present a new shadow contrastive learning mechanism (SCOTCH) which aims at guiding the network to learn a unified shadow representation from massive positive shadow pairs across different videos. We demonstrate empirically the effectiveness of our two contributions in an ablation study. Furthermore, we show that SCOTCH and SODA significantly outperforms existing techniques for video shadow detection. Code is available at the project page: https://lihaoliu-cambridge.github.io/scotch_and_soda/Comment: Accepted to CVPR 202

    Vulnérabilités liées à l'eau dans les Andes vénézuéliennes : influences des relations sociétés/hydrosystèmes dans le cas de Santa-Cruz-de-Mora

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    International audienceDes mutations agricoles sont survenues au cours des dernières décennies dans les Andes vénézuéliennes. Cette région autrefois grande productrice de café a vu sa production baisser au profit du maraîchage irrigué et du pastoralisme. Nous avons mené 2 démarches parallèles : la caractérisation des changements d'occupation du sol afin de mettre en perspective le discours des habitants ; et l'analyse des représentations sociales des risques liés à l'eau, restitués plus largement dans les représentations des hydrosystèmes

    Differential β₂-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines

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    Breast cancer is the most frequent malignancy in women. Several reports demonstrated that adrenergic receptors (ARs) are involved in breast cancer. Here we observed that epinephrine (Epi), an endogenous AR agonist, caused opposite effects in non-tumorigenic (MCF-10A and HBL-100) and tumor cells (MCF-7 and MDA-MB-231). Thus, Epi, in non-tumor breast cells, as well as isoproterenol (β-agonist), in all cell lines, maintained a benign phenotype, decreasing cell proliferation and migration, and stimulating cell adhesion. β-AR expression and cAMP levels were higher in MCF-10A than in MCF-7 cells. β₂-AR knock-down caused a significant increase of cell proliferation and migration, and a decrease of cell adhesion both in basal and in Iso-stimulated conditions. Coincidently, β₂-AR over-expression induced a significant decrease of cell proliferation and migration, and an increase of cell adhesion. Therefore, β₂-AR is implied in cell phenotype and its agonists or antagonists could eventually complement cancer therapy.Fil: Gargiulo, Lucía. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Copsel, Sabrina Natalia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología; ArgentinaFil: Rivero, Ezequiel Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Galés, Céline. Inserm; FranciaFil: Sénard, Jean Michel. Inserm; FranciaFil: Luthy, Isabel Alicia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Davio, Carlos Alberto. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología; ArgentinaFil: Bruzzone, Ariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentin
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