4,871 research outputs found
CS11 COST-EFFECTIVENESS OF SELECTIVE SEROTONIN REUPTAKE INHIBITORS IN THE TREATMENT OF MAJOR DEPRESSION IN MEXICO
Puesta en valor de los recursos fitogenéticos y servicios ambientales del campo natural del palmar de Butia odorata (Barb. Rodr.) Noblick En Uruguay.
Role of dipolar interactions in a system of Ni nanoparticles studied by magnetic susceptibility measurements
The role of dipolar interactions among Ni nanoparticles (NP) embedded in an
amorphous SiO2/C matrix with different concentrations has been studied
performing ac magnetic susceptibility Chi_ac measurements. For very diluted
samples, with Ni concentrations < 4 wt % Ni or very weak dipolar interactions,
the data are well described by the Neel-Arrhenius law. Increasing Ni
concentration to values up to 12.8 wt % Ni results in changes in the
Neel-Arrhenius behavior, the dipolar interactions become important, and need to
be considered to describe the magnetic response of the NPs system. We have
found no evidence of a spin-glasslike behavior in our Ni NP systems even when
dipolar interactions are clearly present.Comment: 7 pages, 5 figures, 3 table
Field-induced magnetic anisotropy in La0.7Sr0.3CoO3
Magnetic anisotropy has been measured for the ferromagnetic La0.7Sr0.3CoO3
perovskite from an analysis of the high-field part of the magnetization vs.
field curves, i.e., the magnetic saturation regime. These measurements give a
magnetic anistropy one order of magnitude higher than that of reference
manganites. Surprisingly, the values of the magnetic anisotropy calculated in
this way do not coincide with those estimated from measurements of coercive
fields which are one order of magnitude smaller. It is proposed that the reason
of this anomalous behaviour is a transition of the trivalent Co ions under the
external magnetic field from a low-spin to an intermediate-spin state. Such a
transition converts the Co3+ ions into Jahn-Teller ions having an only
partially quenched orbital angular momentum, which enhances the intra-atomic
spin-orbit coupling and magnetic anisotropy.Comment: Accepted of publication in Europhysics Letters, 11 pages, 5 figure
Lower Cretaceous (Hauterivian-Albian) ammonite biostratigraphy in the Maestrat Basin (E Spain)
Peer reviewedPublisher PD
Pulmonary metastasectomy in colorectal cancer: a prospective study of demography and clinical characteristics of 543 patients in the Spanish colorectal metastasectomy registry (GECMP-CCR)
ObjectivesTo capture an accurate contemporary description of the practice of pulmonary metastasectomy for colorectal carcinoma in one national healthcare system.DesignA national registry set up in Spain by Grupo Español de Cirugía Metástasis Pulmonares de Carcinoma Colo-Rectal (GECMP-CCR).Setting32 Spanish thoracic units.ParticipantsAll patients with one or more histologically proven lung metastasis removed by surgery between March 2008 and February 2010.InterventionsPulmonary metastasectomy for one or more pulmonary nodules proven to be metastatic colorectal carcinoma.Primary and secondary outcome measuresThe age and sex of the patients having this surgery were recorded with the number of metastases removed, the interval between the primary colorectal cancer operation and the pulmonary metastasectomy, and the carcinoembryonic antigen level. Also recorded were the practices with respect to mediastinal lymphadenopathy and coexisting liver metastases.ResultsData were available on 543 patients from 32 units (6–43/unit). They were aged 32–88 (mean 65) years, and 65% were men. In 55% of patients, there was a solitary metastasis. The median interval between the primary cancer resection and metastasectomy was 28 months and the serum carcinoembryonic antigen was low/normal in the majority. Liver metastatic disease was present in 29% of patients at some point prior to pulmonary metastasectomy. Mediastinal lymphadenectomy varied from 9% to 100% of patients.ConclusionsThe data represent a prospective comprehensive national data collection on pulmonary metastasectomy. The practice is more conservative than the impression gained when members of the European Society of Thoracic Surgeons were surveyed in 2006/2007 but is more inclusive than would be recommended on the basis of recent outcome analyses. Further analyses on the morbidity associated with this surgery and the correlation between imaging studies and pathological findings are being published separately by GECMP-CCR
Coexistence of Paramagnetic-Charge-Ordered and Ferromagnetic-Metallic Phases in La0.5Ca0.5MnO3 evidenced by ESR
Throughout a complete Electron Spin Resonance (ESR) and magnetization study
of La0.5Ca0.5MnO3, we discuss about the nature of the complex phase-segregated
state established in this compound below T~210 K. Between TN<T<TC, the ESR
spectra shows two lines characteristic of two different magnetic phases. From
the resonance field (Hr) derived for each line we argue that the
incommensurate-charge-ordering phase (ICO) which coexists with
ferromagnetic-metallic (FMM) clusters in this temperature interval, is mainly
paramagnetic and not antiferromagnetic. The FMM/ICO ratio can be tuned with a
relatively small field, which suggests that the internal energy associated with
those phases is very similar. Below TN, there is an appreciable FM contribution
to the magnetization and the ESR spectra indicates the presence of FM clusters
in an antiferromagnetic matrix (canted). Our results show that ESR could be a
very useful tool to investigate the nature of the phase-separated state now
believed to play a fundamental role in the physics of mixed valent manganites.Comment: 6 pages, 6 figure
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Loss of testosterone impairs anti-tumor neutrophil function.
In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma deaths are male. The immune system is known to play a key role in controlling the growth and spread of malignancies, but whether age- and sex-dependent changes in immune cell function account for this effect remains unknown. Here, we show that in castrated male mice, neutrophil maturation and function are impaired, leading to elevated metastatic burden in two models of melanoma. Replacement of testosterone effectively normalized the tumor burden in castrated male mice. Further, the aberrant neutrophil phenotype was also observed in prostate cancer patients receiving androgen deprivation therapy, highlighting the evolutionary conservation and clinical relevance of the phenotype. Taken together, these results provide a better understanding of the role of androgen signaling in neutrophil function and the impact of this biology on immune control of malignancies
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