888 research outputs found
The integration of idioms of distress into mental health assessments and interventions: a systematic review
Background:
Psychiatric diagnostic manuals recognise the importance of local expressions of distress in culturally diverse settings [i.e. idioms/cultural concepts of distress (CCDs)], yet there is a lack of consensus on how these should be incorporated into mental health related research.
Aims:
To perform a narrative synthesis and critical review of research exploring how idioms/CCDs have been integrated into assessment measures and interventions.
Method:
A systematic review was conducted in accordance with PRISMA guidelines. An adapted version of the COSMIN checklist was used to assess the quality of the linguistic translation of the idioms/CCDs.
Results:
Twenty-nine papers were included in the final review. Primary qualitative research was the most common method of gathering information about idioms/CCDs. The majority of studies described integrating idioms/CCDs into assessment measures as opposed to interventions. Some studies used information relating to idioms/CCDs to develop novel assessment measures, while others adapted pre-existing assessment measures. The measures generated moderate to high levels of validity. Information relating to the linguistic translation conducted in the completion of the studies tended to be inadequately reported.
Conclusions:
Integrating information about idioms/CCDs into assessment measures can enhance the validity of these assessments. Allocating greater research attention to idioms/CCDs can also promote more equitable exchanges of knowledge about mental health and wellbeing between the Global North and the Global South
Physiology of purple sulfur bacteria forming macroscopic aggregates in Great Sippewissett Salt Marsh, Massachusetts
Abstract Purple bacterial aggregates found in tidal pools of Great Sippewissett Salt Marsh (Falmouth, Cape Cod, MA) were investigated in order to elucidate the ecological significance of cell aggregation. Purple sulfur bacteria were the dominant microorganisms in the aggregates which also contained diatoms and a high number of small rod-shaped bacteria. Urea in concentrations of ≥ 1 M caused disintegration of the aggregates while proteolytic enzymes, surfactants or chaotropic agents did not exhibit this effect. This suggests that polysaccharides in the embedding slime matrix stabilize the aggregate structure. In addition cell surface hydrophobicity is involved in aggregate formation. The concentration of dissolved oxygen decreased rapidly below the surface of aggregates while sulfide was not detected. The apparent respiration rate in the aggregates was high when the purple sulfur bacteria contained intracellular sulfur globules. In the presence of DCMU, respiration remained light-inhibited. Light inhibition disappeared in the presence of KCN. These results demonstrated that respiration in the aggregates is due mainly to purple sulfur bacteria. The concentration of bacteriochlorophyll (Bchl) a in the aggregates (0.205 mg Bchl a cm−3) was much higher than in the pool sediments but comparable to concentrations in microbial mats of adjacent sand flats. Purple aggregates may therefore originate in the microbial mats rather than in the pools themselves. Rapid sedimentation and high respiration rates of Chromatiaceae in the aggregates would prevent the inhibition of Bchl synthesis if aggregates were lifted off the sediment and up into the oxic pool water by tidal currents
Antimony and bismuth oxide cluster ions
The formation of charged antimony and bismuth oxide clusters in a pulsed arc cluster ion source (PACIS) has been studied with time-of-Ñight mass spectrometric techniques. We compare series of antimony and bismuth oxide cluster anions with their known cationic counterparts. The anionic series and (M 2 O 3 ) n MO 2h ave been predicted proceeding from the known cationic series and n Ob y adding O2~and have been experimentally established. All these series contain the metal atoms (M \ Sb or Bi) in the formal oxidation state ]3. However, only in the case of antimony, oxygen rich oxide clusters appear, that can be explained with a gradual transition in the oxidation number from ]3 to ]5 of single antimony atoms in the cluster. To estimate the inÑuence of the special oxide formation conditions comparative investigations with the PACIS and a laser vaporisation cluster source have been carried out for bismuth oxide cations. The similar oxide cluster distributions at comparable oxygen availability display clearly that the special thermodynamical stability of the discussed magic clusters is the signiÐcant driving force for their formation
Gyrate atrophy of the choroid and retina with hyper-ornithinemia responsive to vitamin B6: a case report
<p>Abstract</p> <p>Background</p> <p>Gyrate atrophy of the retina and choroid is a rare autosomal recessive inherited disease, characterized by progressive chorioretinal atrophy that results in progressive deterioration of peripheral and night vision and leading to blindness.</p> <p>Case presentation</p> <p>This report presents a case of a 28-year-old man consulting for a progressive fall of visual acuity with hemeralopia. Eye fundoscopy showed regions of confluent rounded chorioretinal atrophy. The visual field and retinal angiography were altered. A high level of plasma ornithine (629 nmol/mL) was detected and a diagnosis of gyrate atrophy of the retina and choroid was made. The patient was treated with high dose Pyridoxine supplement (300 mg/d for 6 months) and the ornithine level of his serum was successfully reduced.</p> <p>Conclusion</p> <p>The exact mechanism of chorioretinal atrophy in hyper-ornithinemia is not known and a small percentage of the affected people respond to Vitamin B6 supplementation.</p
The Imprint of Galaxy Formation on X-ray Clusters
It is widely believed that structure in the Universe evolves hierarchically,
as primordial density fluctuations, amplified by gravity, collapse and merge to
form progressively larger systems. The structure and evolution of X-ray
clusters, however, seems at odds with this hierarchical scenario for structure
formation. Poor clusters and groups, as well as most distant clusters detected
to date, are substantially fainter than expected from the tight relations
between luminosity, temperature and redshift predicted by these models. Here we
show that these discrepancies arise because, near the centre, the entropy of
the hot, diffuse intracluster medium (ICM) is higher tha possible if the ICM
is heated at modest redshift (z \ltsim 2) but prior to cluster collapse,
indicating that the formation of galaxies precedes that of clusters and that
most clusters have been assembled very recently.Comment: 5 pages, plus 2 postscript figures (one in colour), accepted for
publication in Natur
The inevitable youthfulness of known high-redshift radio galaxies
Radio galaxies can be seen out to very high redshifts, where in principle
they can serve as probes of the early evolution of the Universe. Here we show
that for any model of radio-galaxy evolution in which the luminosity decreases
with time after an initial rapid increase (that is, essentially all reasonable
models), all observable high-redshift radio-galaxies must be seen when the
lobes are less than 10^7 years old. This means that high-redshift radio
galaxies can be used as a high-time-resolution probe of evolution in the early
Universe. Moreover, this result helps to explain many observed trends of
radio-galaxy properties with redshift [(i) the `alignment effect' of optical
emission along radio-jet axes, (ii) the increased distortion in radio
structure, (iii) the decrease in physical sizes, (iv) the increase in radio
depolarisation, and (v) the increase in dust emission] without needing to
invoke explanations based on cosmology or strong evolution of the surrounding
intergalactic medium with cosmic time, thereby avoiding conflict with current
theories of structure formation.Comment: To appear in Nature. 4 pages, 2 colour figures available on request.
Also available at http://www-astro.physics.ox.ac.uk/~km
Social participation and heat-related behavior in older adults during heat waves and on other days
Anisotropic interactions of a single spin and dark-spin spectroscopy in diamond
The nitrogen-vacancy (N-V) center in diamond is a promising atomic-scale
system for solid-state quantum information processing. Its spin-dependent
photoluminescence has enabled sensitive measurements on single N-V centers,
such as: electron spin resonance, Rabi oscillations, single-shot spin readout
and two-qubit operations with a nearby 13C nuclear spin. Furthermore, room
temperature spin coherence times as long as 58 microseconds have been reported
for N-V center ensembles. Here, we have developed an angle-resolved
magneto-photoluminescence microscopy apparatus to investigate the anisotropic
electron spin interactions of single N-V centers at room temperature. We
observe negative peaks in the photoluminescence as a function of both magnetic
field magnitude and angle that are explained by coherent spin precession and
anisotropic relaxation at spin level anti-crossings. In addition, precise field
alignment unmasks the resonant coupling to neighboring dark nitrogen spins that
are not otherwise detected by photoluminescence. The latter results demonstrate
a means of investigating small numbers of dark spins via a single bright spin
under ambient conditions.Comment: 13 pages, 4 figure
A Short Version of the Revised ‘Experience of Close Relationships Questionnaire’: Investigating Non-Clinical and Clinical Samples
- …