65 research outputs found
Manejo nutricional de cĂŁes e gatos domiciliados no estado do EspĂrito Santo - Brasil
Highly-parallelized simulation of a pixelated LArTPC on a GPU
The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The algorithms have been written in Python and translated into CUDA kernels using Numba, a just-in-time compiler for a subset of Python and NumPy instructions. The GPU implementation achieves a speed up of four orders of magnitude compared with the equivalent CPU version. The simulation of the current induced on 10^3 pixels takes around 1 ms on the GPU, compared with approximately 10 s on the CPU. The results of the simulation are compared against data from a pixel-readout LArTPC prototype
Identification and evaluation of security activities in agile projects
We compare four high-profile waterfall security-engineering processes (CLASP,
Microsoft SDL, Cigital Touchpoints and Common Criteria) with the available
preconditions within agile processes. Then, using a survey study, agile
security activities are identified and evaluated by practitioners from large
companies, e.g. software and telecommunication companies. Those activities are
compared and a specific security engineering process is suggested for an agile
process setting that can provide high benefit with low integration cost
Monitoring the effect of antagonist on P53-MDM2 interaction with NMR spectroscopy. Recent results
Intracellular signaling cascades triggered by the NK1 fragment of hepatocyte growth factor in human prostate epithelial cell line PNT1A
Hepatocyte Growth Factor (HGF)/c-MET signaling has an emerging role in promoting cell proliferation,
survival, migration, wound repair and branching in a variety of cell types. HGF plays a crucial role as a
mediator of stromalâepithelial interactions in the normal prostate but the precise biological function of HGF/
c-Met interaction in the normal prostate and in prostate cancer is not clear. HGF has two naturally occurring
splice variants and NK1, the smallest of these HGF variants, consists of the HGF amino terminus through the
first kringle domain. We evaluated the intracellular signaling cascades and the morphological changes
triggered by NK1 in human prostate epithelial cell line PNT1A which shows molecular and biochemical
properties close to the normal prostate epithelium. We demonstrated that these cells express a functional c-
MET, and cell exposure to NK1 induces the phosphorylation of tyrosines 1313/1349/1356 residues of c-MET
which provide docking sites for signaling molecules. We observed an increased phosphorylation of ERK1/2,
Akt, c-Src, p125FAK, SMAD2/3, and STAT3, down-regulation of the expression of epithelial cellâcell adhesion
marker E-cadherin, and enhanced expression levels of mesenchymal markers vimentin, fibronectin, vinculin,
α-actinin, and α-smooth muscle actin. This results in cell proliferation, in the appearance of a mesenchymal
phenotype, in morphological changes resembling cell scattering and in wound healing. Our findings highlight
the function of NK1 in non-tumorigenic human prostatic epithelial cells and provide a picture of the signaling
pathways triggered by NK1 in a unique cell line
Enhancing Phenol Conversion Rates in Saline Anaerobic Membrane Bioreactor Using Acetate and Butyrate as Additional Carbon and Energy Sources
Phenolic industrial wastewater, such as those from coal gasification, are considered a challenge for conventional anaerobic wastewater treatment systems because of its extreme characteristics such as presence of recalcitrant compounds, high toxicity, and salinity. However, anaerobic membrane bioreactors (AnMBRs) are considered of potential interest since they retain all micro-organism that are required for conversion of the complex organics. In this study, the degradation of phenol as main carbon and energy source (CES) in AnMBRs at high salinity (8.0 g Na+â
Lâ1) was evaluated, as well as the effect of acetate and an acetate-butyrate mixture as additional CES on the specific phenol conversion rate and microbial community structure. Three different experiments in two lab-scale (6.5 L) AnMBRs (35°C) were conducted. The first reactor (R1) was fed with phenol as the main CES, the second reactor was fed with phenol and either acetate [2 g CODâ
Lâ1], or a 2:1 acetate-butyrate [2 g CODâ
Lâ1] mixture as additional CES. Results showed that phenol conversion could not be sustained when phenol was the sole CES. In contrast, when the reactor was fed with acetate or an acetate-butyrate mixture, specific phenol conversion rates of 115 and 210 mgPhâ
gVSSâ1 dâ1, were found, respectively. The syntrophic phenol degrader Syntrophorhabdus sp. and the acetoclastic methanogen Methanosaeta sp. were the dominant bacteria and archaea, respectively, with corresponding relative abundances of up to 63 and 26%. The findings showed that dosage of additional CES allowed the development of a highly active phenol-degrading biomass, potentially improving the treatment of industrial and chemical wastewaters.Sanitary Engineerin
Influence of Campus Recreation Facilities on Decision to Attend a Southeastern University: A Pilot Study
Survey response rate levels and trends in organizational research.
This study examines the response rates for surveys used in organizational research. We analysed 1607 studies published in the years 2000 and 2005 in 17 refereed academic journals, and we identified 490 different studies that utilized surveys. We examined the response rates in these studies, which covered more than 100,000 organizations and 400,000 individual respondents. The average response rate for studies that utilized data collected from individuals was 52.7 percent with a standard deviation of 20.4, while the average response rate for studies that utilized data collected from organizations was 35.7 percent with a standard deviation of 18.8. Key insights from further analysis include relative stability in response rates in the past decade and higher response rates for journals published in the USA. The use of incentives was not found to be related to response rates and, for studies of organizations, the use of reminders was associated with lower response rates. Also, electronic data collection efforts (e.g. email, phone, web) resulted in response rates as high as or higher than traditional mail methodology. We discuss a number of implications and recommendations
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