Trypanosomes of the subgenus Megatrypanum from armadillos (Xenarthra: Dasypodidae).

A new species of trypanosome, Trypanosoma (Megatrypanum) peba, is described from the peripheral blood of the armadillo Euphractus sexcinctus setosus from Bahia State, Brazil. Ten out of 29 specimens of the armadillo Dasypus novemcinctus from Pará State were found to have trypanosomes, including epimastigote forms, in impression smears of subcutaneous lymph nodes. The trypanosomes from D. novemcinctus are illustrated and were identified a idenrified as belonging to the subgenus Megatrypanum on the basis of their general appearance, although they failed to multiply is blood-agar culture medium and no bloodstream forms were seen. This is the first published record of trypanosomes of this subgenus from armdillos and the first demonstration of epimastigote trypanosomes in the mammalian host other than in the bloodstream, or in the anal glands of opssums

Comparing Effectiveness of Top-Down and Bottom-Up Strategies in Containing Influenza

This research compares the performance of bottom-up, self-motivated behavioral interventions with top-down interventions targeted at controlling an “Influenza-like-illness”. Both types of interventions use a variant of the ring strategy. In the first case, when the fraction of a person's direct contacts who are diagnosed exceeds a threshold, that person decides to seek prophylaxis, e.g. vaccine or antivirals; in the second case, we consider two intervention protocols, denoted Block and School: when a fraction of people who are diagnosed in a Census Block (resp., School) exceeds the threshold, prophylax the entire Block (resp., School). Results show that the bottom-up strategy outperforms the top-down strategies under our parameter settings. Even in situations where the Block strategy reduces the overall attack rate well, it incurs a much higher cost. These findings lend credence to the notion that if people used antivirals effectively, making them available quickly on demand to private citizens could be a very effective way to control an outbreak

Early responses to H7N9 in southern mainland China

This article is made available through the Brunel Open Access Publishing Fund. © 2014 Goodwin and Sun; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Background: H7N9 posed potentially serious health challenges for Chinese society. The previous SARS outbreak in this country was accompanied by contradictory information, while worries about wide-spread influenza led to discrimination worldwide. Early understanding of public threat perceptions is therefore important for effective public health communication and intervention. Methods: We interviewed 1011 respondents by phone two weeks after the first case. Questions examined risk awareness and media use, beliefs about the emergence of the threat and those most at risk, anxiety about infection and preventive and avoidant behaviours. Results: Results demonstrate moderate levels of anxiety but relatively high levels of trust towards government officials. Threat emergence was associated with hygiene levels, temperature change, floating pigs in the Huangpu River and migration to the city. Anxiety predicted both recommended and non-recommended behavioural changes. Conclusions: Comparatively high levels of trust in Chinese government advice about H7N9 contrast positively with previous pandemic communications in China. Anxiety helped drive both recommended and non-recommended behaviours, with potentially important economic and social implications. This included evidence of 'othering’ of those associated with the threat (e.g. migrants). Findings emphasise the need to manage public communications early during new influenza outbreaks.Fudan Tydall Centre and Fudan Media and Public Opinion Center

Applications of Google Earth Engine in fluvial geomorphology for detecting river channel change

© 2020 The Authors. Cloud-based computing, access to big geospatial data, and virtualization, whereby users are freed from computational hardware and data management logistics, could revolutionize remote sensing applications in fluvial geomorphology. Analysis of multitemporal, multispectral satellite imagery has provided fundamental geomorphic insight into the planimetric form and dynamics of large river systems, but information derived from these applications has largely been used to test existing concepts in fluvial geomorphology, rather than for generating new concepts or theories. Traditional approaches (i.e., desktop computing) have restricted the spatial scales and temporal resolutions of planimetric river channel change analyses. Google Earth Engine (GEE), a cloud-based computing platform for planetary-scale geospatial analyses, offers the opportunity to relieve these spatiotemporal restrictions. We summarize the big geospatial data flows available to fluvial geomorphologists within the GEE data catalog, focus on approaches to look beyond mapping wet channel extents and instead map the wider riverscape (i.e., water, sediment, vegetation) and its dynamics, and explore the unprecedented spatiotemporal scales over which GEE analyses can be applied. We share a demonstration workflow to extract active river channel masks from a section of the Cagayan River (Luzon, Philippines) then quantify centerline migration rates from multitemporal data. By enabling fluvial geomorphologists to take their algorithms to petabytes worth of data, GEE is transformative in enabling deterministic science at scales defined by the user and determined by the phenomena of interest. Equally as important, GEE offers a mechanism for promoting a cultural shift toward open science, through the democratization of access and sharing of reproducible code.Natural Environment Research Council. Grant Number: NE/S00331

Correlated dynamics in egocentric communication networks

We investigate the communication sequences of millions of people through two different channels and analyze the fine grained temporal structure of correlated event trains induced by single individuals. By focusing on correlations between the heterogeneous dynamics and the topology of egocentric networks we find that the bursty trains usually evolve for pairs of individuals rather than for the ego and his/her several neighbors thus burstiness is a property of the links rather than of the nodes. We compare the directional balance of calls and short messages within bursty trains to the average on the actual link and show that for the trains of voice calls the imbalance is significantly enhanced, while for short messages the balance within the trains increases. These effects can be partly traced back to the technological constrains (for short messages) and partly to the human behavioral features (voice calls). We define a model that is able to reproduce the empirical results and may help us to understand better the mechanisms driving technology mediated human communication dynamics.Comment: 7 pages, 6 figure

Reducing outcome measures in mental health: a systematic review of the methods

Economic and Social Research Council (ESRC) Grant number ES/J500057/1 and South London and Maudsley NHS Trust