365 research outputs found

    O pastejo de bovinos em pastagem natural compacta moderadamente o solo sem afetar o desenvolvimento das plantas.

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    O objetivo do trabalho foi avaliar efeito do bovino, sob diferentes alturas de pré pastejo de uma pastagem natural, na qualidade estrutural de um Cambissolo Húmico. O trabalho foi realizado no ano de 2018 em Lages/SC. Os tratamentos consistiram em diferentes alturas de pré pastejo de uma pastagem natural com predomínio de Andropogon lateralis Nees, de 12, 20, 28 e 36 cm, em um sistema de pastejo rotacionado com 40 % de severidade. Adjunto ao protocolo foi mantida uma área de exclusão ao pastejo. Avaliamos a qualidade estrutural do solo ao cessarem os pastejos da temporada de 2018. Não houve alteração da estrutura do solo nas regiões de touceira e entre touceira do capim caninha entre as alturas de pré pastejo, mas todos os tratamentos pastejados aumentaram o grau de compactação na região de entre touceira na superfície do solo (0-5 cm) para a faixa de 80 a 90%, considerada ótima para as plantas, comparativamente à área de exclusão, que apresentou um grau de compactação de 78%. O pastejo ocasionou uma compactação moderada na superfície do solo que não compromete os processos do solo e o crescimento e desenvolvimento das plantas

    PU.1 controls fibroblast polarization and tissue fibrosis

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    Fibroblasts are polymorphic cells with pleiotropic roles in organ morphogenesis, tissue homeostasis and immune responses. In fibrotic diseases, fibroblasts synthesize abundant amounts of extracellular matrix, which induces scarring and organ failure. By contrast, a hallmark feature of fibroblasts in arthritis is degradation of the extracellular matrix because of the release of metalloproteinases and degrading enzymes, and subsequent tissue destruction. The mechanisms that drive these functionally opposing pro-fibrotic and pro-inflammatory phenotypes of fibroblasts remain unknown. Here we identify the transcription factor PU.1 as an essential regulator of the pro-fibrotic gene expression program. The interplay between transcriptional and post-transcriptional mechanisms that normally control the expression of PU.1 expression is perturbed in various fibrotic diseases, resulting in the upregulation of PU.1, induction of fibrosis-associated gene sets and a phenotypic switch in extracellular matrix-producing pro-fibrotic fibroblasts. By contrast, pharmacological and genetic inactivation of PU.1 disrupts the fibrotic network and enables reprogramming of fibrotic fibroblasts into resting fibroblasts, leading to regression of fibrosis in several organs

    Bio-inspired relevant interaction modelling in cognitive crowd management

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    Cognitive algorithms, integrated in intelligent systems, represent an important innovation in designing interactive smart environments. More in details, Cognitive Systems have important applications in anomaly detection and management in advanced video surveillance. These algorithms mainly address the problem of modelling interactions and behaviours among the main entities in a scene. A bio-inspired structure is here proposed, which is able to encode and synthesize signals, not only for the description of single entities behaviours, but also for modelling cause–effect relationships between user actions and changes in environment configurations. Such models are stored within a memory (Autobiographical Memory) during a learning phase. Here the system operates an effective knowledge transfer from a human operator towards an automatic systems called Cognitive Surveillance Node (CSN), which is part of a complex cognitive JDL-based and bio-inspired architecture. After such a knowledge-transfer phase, learned representations can be used, at different levels, either to support human decisions, by detecting anomalous interaction models and thus compensating for human shortcomings, or, in an automatic decision scenario, to identify anomalous patterns and choose the best strategy to preserve stability of the entire system. Results are presented in a video surveillance scenario , where the CSN can observe two interacting entities consisting in a simulated crowd and a human operator. These can interact within a visual 3D simulator, where crowd behaviour is modelled by means of Social Forces. The way anomalies are detected and consequently handled is demonstrated, on synthetic and also on real video sequences, in both the user-support and automatic modes

    Metric Evolution Maps:Multidimensional Attribute-driven Exploration of Software Repositories

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    Understanding how software entities in a repository evolve over time is challenging, as an entity has many aspects that undergo such changes. We cast this problem in a multidimensional visualization context: First, we capture change by extracting quality metrics from all software entities in all revisions in a software repository, yielding a multidimensional time-dependent dataset. Next, we propose Metric Evolution Maps (MEMs), a new visual approach to create dynamic maps that show the similarity of entities in a revision and changes across revisions. We enrich MEMs with visual cues to show which metrics and metric values are key to formation of similar-entity patterns. Additionally, we show how entities change between revisions, and due to which metrics. We illustrate our approach by exploring changes in two real-world software repositories

    Biochemical quality of cowpea beans grown under water-deficit maintained with hydrogel

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    Investigations related to the effects of the hydrogel use in a water-deficit conditions on the biochemical composition of the harvested products are scarce. The aim of this study was to verify the influence of hydrogel on the biochemical response of cowpea beans produced under water-deficit in southern Tocantins. The experiment was a randomized complete block design with four replications. The treatments were obtained in a 2x5 factorial scheme, being: two sources of hydrogel (Hydroplan-EB HyC and Polim-Agri PP) and five concentrations (0, 5, 10, 15, and 20kg ha-1). After harvesting, the grains of cowpea, BRS Vinagre cultivar, were ground and chemically analyzed. The oil content of the seeds agreed with the reference values. The use of Polim-Agri PP promoted the best levels of amino acids (0.38mg g-1) and proteins (243.22mg g-1) of the grains. The carbohydrate content of them (Ȳ= 81.44mg g-1) was better using Hydroplan-EB HyC, regardless of the concentration applied. The application of 6.28kg ha-1 of Polim-Agri PP provided the highest starch content (842g mg-1). The use of hydrogel improves the biochemical quality of cowpea beans produced under water deficit in southern Tocantins

    Clinical presentation, histological findings, and prognosis in female dogs with mixed mammary neoplasms

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    ABSTRACT The aim of this study was to describe the clinical and morphological characteristics of mixed mammary neoplasms and verify what characteristics affect the prognosis of female dogs with carcinomas in mixed tumors and carcinosarcomas. This was a retrospective study of 67 female dogs that underwent mastectomies and were diagnosed with benign mixed tumors (n=13), carcinomas in mixed tumors (n=44) and carcinosarcomas (n=10). Data regarding the clinical and histological aspects of the neoplasms were collected and the relation with specific survival times, and hazard ratios (HR) in 24 months was calculated. In univariate analysis, the diagnosis of carcinosarcoma (HR 8.26, p=0.006), carcinomatous areas with micropapillary or solid patterns (HR 17.49; p=0. 001) and lymph node metastasis (HR 7.07;p=0.020) were associated with specific survival. In multivariable analysis, only micropapillary or solid pattern (HR=16.34; p=0.007) remained independent factor associated with lower specific survival. Micropapillary or solid carcinomatous patterns were associated with shorter specific survival time (p=0.002) among animals with carcinomas in mixed tumors. Among the carcinosarcomas, lymph node metastasis (p=0.010) was associated with a shorter specific survival time. In conclusion, carcinomas in mixed tumors and carcinosarcomas vary in prognosis depending on the carcinomatous proliferation patterns and spread of the disease
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