Responsabilidad social empresarial : decisiones, reflexiones y casos de estudio

Esta obra es resultado del esfuerzo conjunto realizado por miembros de la Asociación Latinoamericana de Casos (ALAC), el Centro Internacional de Casos del Tecnológico de Monterrey (México) y la Universidad del Norte (Colombia). Contiene una selección de trabajos que versan sobre la problemática de la responsabilidad social empresarial en América Latina, la visión de la cultura y el devenir histórico acerca de este tema y una serie de casos que, sin lugar a dudas, se constituyen en un aporte significativo a los procesos de enseñanza-aprendizaje respecto a la ética empresarial y la responsabilidad social

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field

Gestión del conocimiento: perspectiva multidisciplinaria. Volumen 13

El libro “Gestión del Conocimiento. Perspectiva Multidisciplinaria”, Volumen 13 de la Colección Unión Global, es resultado de investigaciones. Los capítulos del libro, son resultados de investigaciones desarrolladas por sus autores. El libro es una publicación internacional, seriada, continua, arbitrada, de acceso abierto a todas las áreas del conocimiento, orientada a contribuir con procesos de gestión del conocimiento científico, tecnológico y humanístico. Con esta colección, se aspira contribuir con el cultivo, la comprensión, la recopilación y la apropiación social del conocimiento en cuanto a patrimonio intangible de la humanidad, con el propósito de hacer aportes con la transformación de las relaciones socioculturales que sustentan la construcción social de los saberes y su reconocimiento como bien público. El libro “Gestión del Conocimiento. Perspectiva Multidisciplinaria”, Volumen 13, de la Colección Unión Global, es resultado de investigaciones. Los capítulos del libro, son resultados de investigaciones desarrolladas por sus autores. El libro cuenta con el apoyo de los grupos de investigación: Universidad Sur del Lago “Jesús María Semprúm” (UNESUR) - Zulia – Venezuela; Universidad Politécnica Territorial de Falcón Alonso Gamero (UPTFAG) - Falcón – Venezuela; Universidad Politécnica Territorial de Mérida Kléber Ramírez (UPTM) - Mérida - Venezuela; Universidad Guanajuato (UG) - Campus Celaya - Salvatierra - Cuerpo Académico de Biodesarrollo y Bioeconomía en las Organizaciones y Políticas Públicas (CABBOPP) - Guanajuato – México; Centro de Altos Estudios de Venezuela (CEALEVE) - Zulia – Venezuela, Centro Integral de Formación Educativa Especializada del Sur (CIFE - SUR) - Zulia – Venezuela; Centro de Investigaciones Internacionales SAS (CEDINTER) - Antioquia – Colombia y diferentes grupos de investigación del ámbito nacional e internacional que hoy se unen para estrechar vínculos investigativos, para que sus aportes científicos formen parte de los libros que se publiquen en formatos digital e impreso

Demographic trajectories of Baja California and California, 1900-2000. Contrasts and parallelisms

The purpose is to analyze migration processes that have occurred in two neighboring states, pointing out the characteristics acquired in each of them, especially regarding their origin and type of labor relations they have produced. Therefore, the migration as the thematic axis and following the guidelines of comparative history, it is shown that both in California and in Baja California, migration flows have played a fundamental role. The comparative appro­ach also leads to the search for similarities and differences represented in different moments, such as the impact of "Prohibition", the Great Depression and two World Wars, or specific phenomena as the arrival of the railroad. But above all, the common thread is migration with its two key issues mentioned above, the origin of migration flows and labor relations that they have generated in the two Californias

Trayectorias demográficas de Baja California y California, 1900–2000.: Contrastes y paralelismos

The purpose is to analyze migration processes that have occurred in two neighboring states, pointing out the characteristics acquired in each of them, especially regarding their origin and type of labor relations they have produced. Therefore, the migration as the thematic axis and following the guidelines of comparative history, it is shown that both in California and in Baja California, migration flows have played a fundamental role. The comparative appro­ach also leads to the search for similarities and differences represented in different moments, such as the impact of "Prohibition", the Great Depression and two World Wars, or specific phenomena as the arrival of the railroad. But above all, the common thread is migration with its two key issues mentioned above, the origin of migration flows and labor relations that they have generated in the two Californias.El objetivo de este documento es analizar los procesos de la migración en dos entidades vecinas, California y Baja California, señalando sus características, la procedencia de los flujos migratorios y el tipo de relaciones laborales generadas a partir de este fenómeno. Por ello, con la migración como eje temático y siguiendo las pautas de la historia comparativa, se constata que tanto en California como en Baja California los flujos migratorios han desempeñado un papel fundamental. El enfoque comparativo lleva también a la búsqueda de similitudes y diferencias en etapas y coyunturas clave, como el impacto de la Ley Seca, la Gran Depresión y las dos guerras mundiales, o bien fenómenos específicos como la llegada del ferrocarril. El hilo conductor es la migración con sus dos aspectos fundamentales ya mencionados: la procedencia de las corrientes migratorias y las relaciones laborales que éstas han generado en las dos Californias

Comparison between linseed expeller and canola expeller on concentrate intake, and circulating inflammatory mediators in Holstein calves

The objective of this study was to compare the effect of linseed and canola expeller on average daily weight gain (ADG), concentrate intakes, incidence of diarrhea, serum haptoglobin, interleukin (IL)-1, and resolvin-E1 in female Holstein calves from birth to weaning. A sample size of 20 calves per group was calculated and were randomly allocated at the time of birth. Linseed group (LIN) was fed a starter with linseed expeller, while canola group (CAN) received a similar concentrate, but with canola expeller. Both expellers were included at a rate of 25% dry matter (DM) basis of the starter. Pasteurized waste milk was fed twice a day until weaning. Calves were weighed at birth, 30, and 60 d of age. Starter intake was evaluated daily from 5 to 60 d. A blood sample was obtained at birth, 14, 28, 35, and 49 d of age, and bovine serum resolvin-E1, haptoglobin, and IL-1 were assayed by commercial enzyme-linked immunosorbent assay (ELISA) kits. Incidence of diarrhea and the duration of the events were also recorded. The effect of the interaction group by time on body weight (BW) and starter intake was not significant (P > 0.05). Average daily gains (ADG) from 0 to 60 d for CAN and LIN groups were 0.680 and 0.675 kg/d (P > 0.05), respectively. Incidences of diarrhea were 25% and 45% for CAN and LIN groups, respectively (P = 0.18). LIN group had greater concentrations of IL-1 at d 21, haptoglobin at d 7, and resolving-E1 at d 14 and 49 than CAN group, respectively. It is concluded that BW at weaning, ADG, and concentrate intakes were not different between groups fed starters containing linseed or canola expeller (25% inclusion). The concentrations of cytokines and haptoglobin were the greatest in LIN group

Coronary CT Angiography in Takayasu Arteritis

ObjectivesThe aim of this study was to use coronary computed tomographic (CT) angiography to characterize coronary artery involvement in patients with known Takayasu arteritis who present with anginal chest pain or shortness of breath.BackgroundTakayasu arteritis is a primary vasculitis of the large vessels, which mainly affects the aorta and its branches but can also involve the coronary arteries. Coronary CT angiography allows visualization of the coronary vessels and can be used to detect both stenotic and nonstenotic coronary artery lesions.MethodsEighteen consecutive patients with Takayasu arteritis and angina (typical or atypical) and/or dyspnea underwent contrast-enhanced 64-slice coronary CT angiography. The arterial injury was classified according to the Numano classification. Three patients had prior known coronary artery disease. Coronary arteries were evaluated concerning the presence of obstructive and nonobstructive lesions, and differences between the clinical presentations of patients with and without coronary artery involvement on CT angiography were analyzed.ResultsCoronary artery involvement was found in 8 patients (44.4%), 3 of them with clinical activity. A total of 19 coronary lesions were present (13 in ostial locations, 5 in proximal coronary artery segments, and 1 in a mid segment). Eight lesions exceeded 50% diameter reduction (2 in ostial locations and 6 in proximal coronary artery segments). Median disease duration was significantly different between patients with coronary artery involvement (176 months; range 13 to 282 months) compared with those without (21 months; range 1 to 142 months) (p = 0.013).ConclusionsCoronary CT angiography allows the assessment of coronary artery involvement in patients with Takayasu arteritis. These data confirm prior observations that most coronary lesions are in ostial or proximal coronary artery locations. Disease duration in patients with coronary artery involvement is longer than in patients without

Marine Microalgae as a Nutritive Tool to Mitigate Ruminal Greenhouse Gas Production: In Vitro Fermentation Characteristics of Fresh and Ensiled Maize (<i>Zea mays</i> L.) Forage

The aim of the present study was to evaluate the effects of marine microalgae (Dunaliella salina) as a food additive on biogas (BG), methane (CH4), carbon monoxide (CO), and hydrogen sulfide (H2S) production kinetics, as well as in in vitro rumen fermentation and the CH4 conversion efficiency of different genotypes of maize (Zea mays L.) and states of forage. The treatments were characterized by the forage of five maize genotypes (Amarillo, Montesa, Olotillo, Tampiqueño, and Tuxpeño), two states of forage (fresh and ensiled), and the addition of 3% (on DM basis) of microalgae (with and without). The parameters (b = asymptotic production, c = production rate, and Lag = delay phase before gas production) of the production of BG, CH4, CO, and H2S showed an effect (p p > 0.05). Moreover, the addition of microalgae decreased (p 4, and H2S in most of the genotypes and stages of the forage, but the production of CO increased (p p p p p 4 per unit of SFCA, ME, and OM, and the microalgae increased it (p p 4 per unit of product. In conclusion, the D. salina microalga showed a potential to reduce the production of BG, CH4, and H2S in maize forage, but its effect depended on the chemical composition of the genotype and the state of the forage. Despite the above, the energy value of the forage (fresh and ensiled) improved, the DMD increased, and in some cases, SCFA and ME also increased, all without compromising CH4 conversion efficiency

COMERCIALIZACIÓN DE MASA Y «FRUTO VERDE» DE AGUAJE (Mauritia flexuosa L.f.) EN IQUITOS (PERÚ)

Este trabajo discute la comercialización de frutos de aguaje en forma de masa y«fruto verde» en la ciudad de Iquitos, Perú. Existen 11 mercados en la ciudad. En cuatro de ellos, es ofertada la masa; en dos, el «fruto verde» por 21 y 30 vendedoras, respectivamente. Ambas actividades son llevadas a cabo por mujeres mayores de 40 años, que tienen en promedio cuatro hijos y cuyas parejas, por lo general, no trabajan. Las comercializadoras de masa y «fruto verde» se dedican a esta actividad desde hace 20 años en promedio. Cabe indicar, sin embargo, que la persona más experimentada la realiza desde hace ya 50 años. Las vendedoras ofrecen sus productos durante todo el año, lo que representa un consumo mensual de 3 720 sacos, cantidad para la que se deben cortar aproximadamente 1 078 palmeras.De un saco de aguaje se obtienen en promedio 22 bolsas de masa y 16 bandejaspequeñas de «fruto verde». Esta cantidad rinde, en época de abundancia, utilidades superiores al salario mínimo de un obrero de la actividad privada. Asimismo, durante la época de escasez, el beneficio económico es mayor que el salario de un docente universitario estatal. Los frutos se exportan en cantidades mínimas a otras ciudades del Perú como Tarapoto, Pucallpa y Lima.Las vendedoras han desarrollado técnicas sencillas y rápidas para conocer la madurez fisiológica del fruto y el ecotipo ofertado