DESIGN OF METAOATA SCHEMA FOR COLLECTING, UTILIZING AND PRESERVING BIOMECHANICAL DATA OF WINTER SPORTS EXPERIMENT

The purpose of this study was to present metadata elements for managing biomechanical data of winter sports experiments and to establish an Integrated Data Management System with the presented metadata elements. To sort and select metadata elements, metadata crosswalk was done with four internationally used metadata schema; Dublin Core, OECD, DataCite, MODS. And a new metadata schema was designed with common elements from the crosswalk and the metadata elements drawn from general experimental designs and R&D portal. The schema was applied to a research data platform Datanest and the Integrated Management System for experimental data of winter sports was established

Reconstruction of plasma density profiles by measuring spectra of radiation emitted from oscillating plasma dipoles

We suggest a new method for characterising non-uniform density distributions of plasma by measuring the spectra of radiation emitted from a localised plasma dipole oscillator excited by colliding electromagnetic pulses. The density distribution can be determined by scanning the collision point in space. Two-dimensional particle-in-cell simulations demonstrate the reconstruction of linear and nonlinear density profiles corresponding to laser-produced plasma. The method can be applied to a wide range of plasma, including fusion and low temperature plasmas. It overcomes many of the disadvantages of existing methods that only yield average densities along the path of probe pulses, such as interferometry and spectroscopy

Performance and engine-out emissions evaluation of the double injection strategy applied to the gasoline partially premixed compression ignition spark assisted combustion concept

Spark assistance has been found to improve combustion control when combined with both single and double injection operation applied to compression ignition (CI) engines using gasoline as the fuel. Previous work has verified the potential of a double injection strategy when applied to the gasoline spark assisted partially premixed compression ignition combustion (PPC) concept. The current research presents performance and engine-out emissions results using a double injection strategy with the spark assisted PPC concept and shows its benefits compared to a single injection strategy. For this purpose, a parametric study was carried out using gasoline in a high-speed single-cylinder diesel engine equipped with a modified cylinder head, which included a spark plug. The parameters that were varied during the double injection testing included: injection timing, dwell, fuel mass split between the injections and intake oxygen concentration. A detailed analysis of the air/fuel mixing process was also conducted by means of a 1-D in-house spray model (DICOM)The authors would like to thank General Motors for supporting this research.Benajes Calvo, JV.; Molina Alcaide, SA.; García Martínez, A.; Monsalve Serrano, J.; Durrett, R. (2014). Performance and engine-out emissions evaluation of the double injection strategy applied to the gasoline partially premixed compression ignition spark assisted combustion concept. Applied Energy. 134:90-101. doi:10.1016/j.apenergy.2014.08.008S9010113

An Unusual Cause of Seizure in Clinical Practice

Neurocysticercosis (NCC), the infection caused by the larval stage of the tapeworm Taenia solium, is the most common parasitic disease of the nervous system (NS) in humans, where it is the leading cause of late-onset seizures in the endemic areas. Fortunately it is still rare in Bangladesh due to some religious binding in eating pork. Here we present a young man who came to us with Neurocysticercosis as the cause of recurrent seizure and various neurological manifestations

Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis.

Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms. The endothelium is the thin layer of squamous cells where vascular blood endothelial cells (BECs) line the interior surface of blood vessels and lymphatic endothelial cells (LECs) are in direct contact with lymphatic vessels. The KS lesions contain a prominent compartment of neoplastic spindle morphology cells that are closely related to LECs. Furthermore, while KSHV can infect both LECs and BECs in vitro, its infection activates genetic programming related to lymphatic endothelial cell fate, suggesting that lymphangiogenic pathways are involved in KSHV infection and malignancy. Here, we report for the first time that viral interferon regulatory factor 3 (vIRF3) is readily detected in over 40% of KS lesions and that vIRF3 functions as a proangiogenic factor, inducing hypersprouting formation and abnormal growth in a LEC-specific manner. Mass spectrometry analysis revealed that vIRF3 interacted with histone deacetylase 5 (HDAC5), which is a signal-responsive regulator for vascular homeostasis. This interaction blocked the phosphorylation-dependent cytosolic translocation of HDAC5 and ultimately altered global gene expression in LECs but not in BECs. Consequently, vIRF3 robustly induced spindle morphology and hypersprouting formation of LECs but not BECs. Finally, KSHV infection led to the hypersprouting formation of LECs, whereas infection with a ΔvIRF3 mutant did not do so. Collectively, our data indicate that vIRF3 alters global gene expression and induces a hypersprouting formation in an HDAC5-binding-dependent and LEC-specific manner, ultimately contributing to KSHV-associated pathogenesis.IMPORTANCE Several lines of evidences indicate that KSHV infection of LECs induces pathological lymphangiogenesis and that the results resemble KS-like spindle morphology. However, the underlying molecular mechanism remains unclear. Here, we demonstrated that KSHV vIRF3 is readily detected in over 40% of various KS lesions and functions as a potent prolymphangiogenic factor by blocking the phosphorylation-dependent cytosolic translocation of HDAC5, which in turn modulates global gene expression in LECs. Consequently, vIRF3-HDAC5 interaction contributes to virus-induced lymphangiogenesis. The results of this study suggest that KSHV vIRF3 plays a crucial role in KSHV-induced malignancy

Schooling and immunization of orphaned children in Swaziland

Thesis(Master) --KDI School:Master of Development Policy,2016Swaziland is a HIV/AIDS prevalent country, with the highest affected rate in the world. As a result, the number of orphans has increased over the years. This paper strives to find factors to eliminate inequality in Swazi orphans in education and health. Children from six to fifteen years of age are selected to examine the effect of household wealth and mother’s education level on the enrollment ratio and whether a child is in the officially recommended grade for his/her age in school or not (n=2,970), using logistic regression. Furthermore, children between zero and five years are chosen to see the effect of an immunization card on the number of vaccinations: BCG, polio, and DPT/HepB/Hib (n=1,393) with zero-inflated regression. The data used is from the Swaziland Multiple Indicator Cluster Survey (MICS) in 2010. Although wealth does not significantly affect the education of non-orphans statistically, it becomes more important to orphans along with mother’s education level. An immunization card solves the health inequality of orphans in the number of vaccination in Swaziland. These results imply that the country is recommended to enforce policies on education differently by group and to encourage people to use immunization cards to remove the inequality in education and health caused by loss of parents.1. INTRODUCTION 2. LITERATURE REVIEW A. EDUCATION B. HEALTH 3. METHODOLOGY A. DATA B. VARIABLES C. EMPIRICAL STRATEGIES 4. RESULTS A. EDUCATION B. HEALTH 5. DISCUSSION A. EDUCATION B. HEALTH 6. CONCLUSIONmasterpublishedYu-Ra LEE

Tumorigenicity And Validity Of Fluorescence Labelled Mesenchymal And Epithelial Human Oral Cancer Cell Lines In Nude Mice

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New flexible silicone-based EEG dry sensor material compositions exhibiting improvements in lifespan, conductivity, and reliability

© 2016 by the authors; licensee MDPI, Basel, Switzerland. This study investigates alternative material compositions for flexible silicone-based dry electroencephalography (EEG) electrodes to improve the performance lifespan while maintaining high-fidelity transmission of EEG signals. Electrode materials were fabricated with varying concentrations of silver-coated silica and silver flakes to evaluate their electrical, mechanical, and EEG transmission performance. Scanning electron microscope (SEM) analysis of the initial electrode development identified some weak points in the sensors’ construction, including particle pull-out and ablation of the silver coating on the silica filler. The newly-developed sensor materials achieved significant improvement in EEG measurements while maintaining the advantages of previous silicone-based electrodes, including flexibility and non-toxicity. The experimental results indicated that the proposed electrodes maintained suitable performance even after exposure to temperature fluctuations, 85% relative humidity, and enhanced corrosion conditions demonstrating improvements in the environmental stability. Fabricated flat (forehead) and acicular (hairy sites) electrodes composed of the optimum identified formulation exhibited low impedance and reliable EEG measurement; some initial human experiments demonstrate the feasibility of using these silicone-based electrodes for typical lab data collection applications

Effects of 8-week online, supervised high-intensity interval training on the parameters related to the anaerobic threshold, body weight, and body composition during pregnancy: a randomized controlled trial

We aimed to assess the effects of an 8-week, online high-intensity interval training (HIIT) program on the parameters related to the anaerobic threshold (AT), body weight, and body compo sition in pregnant women. A total of 69 Caucasian women with an uncomplicated singleton preg nancy (age: 31 ± 4 years; gestational age: 22 ± 5 weeks; mean ± standard deviation) were randomly allocated to either an 8-week HIIT program (HIIT group) or to a comparative 8-week educational program (EDU group). Our most important finding was that even with the 8-week progression of pregnancy and physiological weight gain, the HIIT group maintained the same level of parameters related to AT: volume of oxygen at the AT (VO2/AT), percentage of maximal oxygen uptake at the AT (%VO2max/AT), and heart rate at the AT (HR/AT). In contrast, in the EDU group we observed a substantial deterioration of parameters related to the AT. The HIIT intervention substantially re duced the fat mass percentage (median: 30 to 28%; p < 0.01) and improved the total fat-free mass percentage (median: 70% to 72%; p < 0.01). In the EDU group, the body composition did not change significantly. An online, supervised HIIT program may be used to prevent the pregnancy-related risk of excessive weight gain and reduction in exercise capacity without yielding adverse obstetric or neonatal outcomes.info:eu-repo/semantics/publishedVersio