87,017 research outputs found
Fixed-Parameter Tractability of Token Jumping on Planar Graphs
Suppose that we are given two independent sets and of a graph
such that , and imagine that a token is placed on each vertex in
. The token jumping problem is to determine whether there exists a
sequence of independent sets which transforms into so that each
independent set in the sequence results from the previous one by moving exactly
one token to another vertex. This problem is known to be PSPACE-complete even
for planar graphs of maximum degree three, and W[1]-hard for general graphs
when parameterized by the number of tokens. In this paper, we present a
fixed-parameter algorithm for the token jumping problem on planar graphs, where
the parameter is only the number of tokens. Furthermore, the algorithm can be
modified so that it finds a shortest sequence for a yes-instance. The same
scheme of the algorithms can be applied to a wider class of graphs,
-free graphs for any fixed integer , and it yields
fixed-parameter algorithms
Gerasimov-Drell-Hearn Sum Rule and the Discrepancy between the New CLAS and SAPHIR Data
Contribution of the K^+\Lambda channel to the Gerasimov-Drell-Hearn (GDH) sum
rule has been calculated by using the models that fit the recent SAPHIR or CLAS
differential cross section data. It is shown that the two data sets yield quite
different contributions. Contribution of this channel to the forward spin
polarizability of the proton has been also calculated. It is also shown that
the inclusion of the recent CLAS C_x and C_z data in the fitting data base does
not significantly change the result of the present calculation. Results of the
fit, however, reveal the role of the S_{11}(1650), P_{11}(1710), P_{13}(1720),
and P_{13}(1900) resonances for the description of the C_x and C_z data. A
brief discussion on the importance of these resonances is given. Measurements
of the polarized total cross section \sigma_{TT'} by the CLAS, LEPS, and MAMI
collaborations are expected to verify this finding.Comment: 15 pages, 8 figure
Generalized Effective Reducibility
We introduce two notions of effective reducibility for set-theoretical
statements, based on computability with Ordinal Turing Machines (OTMs), one of
which resembles Turing reducibility while the other is modelled after Weihrauch
reducibility. We give sample applications by showing that certain (algebraic)
constructions are not effective in the OTM-sense and considerung the effective
equivalence of various versions of the axiom of choice
The complexity of dominating set reconfiguration
Suppose that we are given two dominating sets and of a graph
whose cardinalities are at most a given threshold . Then, we are asked
whether there exists a sequence of dominating sets of between and
such that each dominating set in the sequence is of cardinality at most
and can be obtained from the previous one by either adding or deleting
exactly one vertex. This problem is known to be PSPACE-complete in general. In
this paper, we study the complexity of this decision problem from the viewpoint
of graph classes. We first prove that the problem remains PSPACE-complete even
for planar graphs, bounded bandwidth graphs, split graphs, and bipartite
graphs. We then give a general scheme to construct linear-time algorithms and
show that the problem can be solved in linear time for cographs, trees, and
interval graphs. Furthermore, for these tractable cases, we can obtain a
desired sequence such that the number of additions and deletions is bounded by
, where is the number of vertices in the input graph
Is silence golden? of mobiles, monitoring,and rural water supplies
Reliable and cost-effective monitoring of rural water supply infrastructure has long been hampered by the geographical curse of dispersed and low-income populations, and weak institutional performance. Recent advances in monitoring technology combined with mobile network expansion into rural areas has created an opportunity to bypass these seemingly intractable challenges. Mobile-enhanced technologies have the potential to produce data that is orders of magnitude richer, faster, and cheaper than that provided by traditional monitoring methods, which require costly field visits. However, more data does not equate to better data; information generated by crowdsourced and automated systems each has its respective limitations. We propose a framework for analysing monitoring and surveillance systems, which can help assess the strengths and weaknesses of different emerging approaches. We suggest that these advancements present an opportunity to fundamentally change the way we consider and conduct rural water supply monitoring. © Practical Action Publishing, 2012
A Transport Analysis of the BEEM Spectroscopy of Au/Si Schottky Barriers
A systematic transport study of the ballistic electron emission microscopy
(BEEM) of Au/Si(100) and Au/Si(111) Schottky barriers for different thicknesses
of the metal layer and different temperatures is presented. It is shown that
the existing experimental data are compatible with a recently predicted
bandstructure-induced non-forward electron propagation through the Au(111)
layer.Comment: 5 pages, Latex-APS, 1 postscript figure,
http://www.icmm.csic.es/Pandres/pedro.htm. Phys. Stat. Sol. (b) (to appear),
HCIS-10 Conf, Berlin 199
Remote activation of host cell DNA synthesis in uninfected cells signalled by infected cells in advance of virus transmission.
Viruses modulate cellular processes and metabolism in diverse ways, but these are almost universally studied in the infected cell itself. Here, we study spatial organization of DNA synthesis during multiround transmission of herpes simplex virus (HSV) using pulse-labeling with ethynyl nucleotides and cycloaddition of azide fluorophores. We report a hitherto unknown and unexpected outcome of virus-host interaction. Consistent with the current understanding of the single-step growth cycle, HSV suppresses host DNA synthesis and promotes viral DNA synthesis in spatially segregated compartments within the cell. In striking contrast, during progressive rounds of infection initiated at a single cell, we observe that infection induces a clear and pronounced stimulation of cellular DNA replication in remote uninfected cells. This induced DNA synthesis was observed in hundreds of uninfected cells at the extended border, outside the perimeter of the progressing infection. Moreover, using pulse-chase analysis, we show that this activation is maintained, resulting in a propagating wave of host DNA synthesis continually in advance of infection. As the virus reaches and infects these activated cells, host DNA synthesis is then shut off and replaced with virus DNA synthesis. Using nonpropagating viruses or conditioned medium, we demonstrate a paracrine effector of uninfected cell DNA synthesis in remote cells continually in advance of infection. These findings have significant implications, likely with broad applicability, for our understanding of the ways in which virus infection manipulates cell processes not only in the infected cell itself but also now in remote uninfected cells, as well as of mechanisms governing host DNA synthesis. IMPORTANCE We show that during infection initiated by a single particle with progressive cell-cell virus transmission (i.e., the normal situation), HSV induces host DNA synthesis in uninfected cells, mediated by a virus-induced paracrine effector. The field has had no conception that this process occurs, and the work changes our interpretation of virus-host interaction during advancing infection and has implications for understanding controls of host DNA synthesis. Our findings demonstrate the utility of chemical biology techniques in analysis of infection processes, reveal distinct processes when infection is examined in multiround transmission versus single-step growth curves, and reveal a hitherto-unknown process in virus infection, likely relevant for other viruses (and other infectious agents) and for remote signaling of other processes, including transcription and protein synthesis
Independent Set Reconfiguration in Cographs
We study the following independent set reconfiguration problem, called
TAR-Reachability: given two independent sets and of a graph , both
of size at least , is it possible to transform into by adding and
removing vertices one-by-one, while maintaining an independent set of size at
least throughout? This problem is known to be PSPACE-hard in general. For
the case that is a cograph (i.e. -free graph) on vertices, we show
that it can be solved in time , and that the length of a shortest
reconfiguration sequence from to is bounded by , if such a
sequence exists.
More generally, we show that if is a graph class for which (i)
TAR-Reachability can be solved efficiently, (ii) maximum independent sets can
be computed efficiently, and which satisfies a certain additional property,
then the problem can be solved efficiently for any graph that can be obtained
from a collection of graphs in using disjoint union and complete join
operations. Chordal graphs are given as an example of such a class
Order preserving pattern matching on trees and DAGs
The order preserving pattern matching (OPPM) problem is, given a pattern
string and a text string , find all substrings of which have the
same relative orders as . In this paper, we consider two variants of the
OPPM problem where a set of text strings is given as a tree or a DAG. We show
that the OPPM problem for a single pattern of length and a text tree
of size can be solved in time if the characters of are
drawn from an integer alphabet of polynomial size. The time complexity becomes
if the pattern is over a general ordered alphabet. We
then show that the OPPM problem for a single pattern and a text DAG is
NP-complete
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