600 research outputs found
PMS48 Cost-Effectiveness of Tocilizumab for The Management of Inadequately Responding Rheumatoid Arthritis Patients
Weiner, LawrencePrimer pla de l'obra. Tres grans
paral·lelepípedes de formigó, amb
aparença de sarcòfags.Repartits al llarg
de l'avinguda. Tots porten uns versos,
escrits el 1845, quan tenia 15 anys, pel
premi Nobel Frederic Mistral
Bounds on the cosmological abundance of primordial black holes from diffuse sky brightness: single mass spectra
We constrain the mass abundance of unclustered primordial black holes (PBHs),
formed with a simple mass distribution and subject to the Hawking evaporation
and particle absorption from the environment. Since the radiative flux is
proportional to the numerical density, an upper bound is obtained by comparing
the calculated and observed diffuse background values, (similarly to the Olbers
paradox in which point sources are considered) for finite bandwidths. For a
significative range of formation redshifts the bounds are better than several
values obtained by other arguments ; and they apply
to PBHs which are evaporating today.Comment: 20 pages, 5 figures, to appear in PR
Tritium Beta Decay, Neutrino Mass Matrices and Interactions Beyond the Standard Model
The interference of charge-changing interactions, weaker than the V-A
Standard Model (SM) interaction and having a different Lorentz structure, with
that SM interaction, can, in principle, produce effects near the end point of
the Tritium beta decay spectrum which are of a different character from those
produced by the purely kinematic effect of neutrino mass expected in the
simplest extension of the SM. We show that the existence of more than one mass
eigenstate can lead to interference effects at the end point that are stronger
than those occurring over the entire spectrum. We discuss these effects both
for the special case of Dirac neutrinos and the more general case of Majorana
neutrinos and show that, for the present precision of the experiments, one
formula should suffice to express the interference effects in all cases.
Implications for "sterile" neutrinos are noted.Comment: 32 pages, LaTeX, 6 figures, PostScript; full discussion and changes
in notation from Phys. Lett. B440 (1998) 89, nucl-th/9807057; submitted to
Phys. Rev.
Combining Multiple Classifiers with Dynamic Weighted Voting
When a multiple classifier system is employed, one of the most popular methods to accomplish the classifier fusion is the simple majority voting. However, when the performance of the ensemble members is not uniform, the efficiency of this type of voting generally results affected negatively. In this paper, new functions for dynamic weighting in classifier fusion are introduced. Experimental results demonstrate the advantages of these novel strategies over the simple voting scheme
Radio precursors to neutron star binary mergings
We discuss a possible generation of radio bursts preceding final stages of
binary neutron star mergings which can be accompanied by short gamma-ray
bursts. Detection of such bursts appear to be advantageous in the low-frequency
radio band due to a time delay of ten to several hundred seconds required for
radio signal to propagate in the ionized intergalactic medium. This delay makes
it possible to use short gamma-ray burst alerts to promptly monitor specific
regions on the sky by low-frequency radio facilities, especially by LOFAR. To
estimate the strength of the radio signal, we assume a power-law dependence of
the radio luminosity on the total energy release in a magnetically dominated
outflow, as found in millisecond pulsars. Based on the planned LOFAR
sensitivity at 120 MHz, we estimate that the LOFAR detection rate of such radio
transients could be about several events per month from redshifts up to
in the most optimistic scenario. The LOFAR ability to detect such
events would crucially depend on exact efficiency of low-frequency radio
emission mechanism.Comment: 6 pages, 2 figures, Accepted for publication in Astrophysics & Space
Science. Largely extended version of ArXiv:0912.521
l W nu production at CLIC: a window to TeV scale non-decoupled neutrinos
We discuss single heavy neutrino production e+ e- -> N nu -> l W nu, l = e,
mu, tau, at a future high energy collider like CLIC, with a centre of mass
energy of 3 TeV. This process could allow to detect heavy neutrinos with masses
of 1-2 TeV if their coupling to the electron V_eN is in the range 0.004-0.01.
We study the dependence of the limits on the heavy neutrino mass and emphasise
the crucial role of lepton flavour in the discovery of a positive signal at
CLIC energy. We present strategies to determine heavy neutrino properties once
they are discovered, namely their Dirac or Majorana character and the size and
chirality of their charged current couplings. Conversely, if no signal is
found, the bound V_eN < 0.002-0.006 would be set for masses of 1-2 TeV,
improving the present limit up to a factor of 30. We also extend previous work
examining in detail the flavour and mass dependence of the corresponding limits
at ILC, as well as the determination of heavy neutrino properties if they are
discovered at this collider.Comment: LaTeX 32 pages. Added comments and references. Matches version to
appear in JHE
Saturn's icy satellites and rings investigated by Cassini - VIMS. III. Radial compositional variability
In the last few years Cassini-VIMS, the Visible and Infared Mapping
Spectrometer, returned to us a comprehensive view of the Saturn's icy
satellites and rings. After having analyzed the satellites' spectral properties
(Filacchione et al. (2007a)) and their distribution across the satellites'
hemispheres (Filacchione et al. (2010)), we proceed in this paper to
investigate the radial variability of icy satellites (principal and minor) and
main rings average spectral properties. This analysis is done by using 2,264
disk-integrated observations of the satellites and a 12x700 pixels-wide rings
radial mosaic acquired with a spatial resolution of about 125 km/pixel. The
comparative analysis of these data allows us to retrieve the amount of both
water ice and red contaminant materials distributed across Saturn's system and
the typical surface regolith grain sizes. These measurements highlight very
striking differences in the population here analyzed, which vary from the
almost uncontaminated and water ice-rich surfaces of Enceladus and Calypso to
the metal/organic-rich and red surfaces of Iapetus' leading hemisphere and
Phoebe. Rings spectra appear more red than the icy satellites in the visible
range but show more intense 1.5-2.0 micron band depths. The correlations among
spectral slopes, band depths, visual albedo and phase permit us to cluster the
saturnian population in different spectral classes which are detected not only
among the principal satellites and rings but among co-orbital minor moons as
well. Finally, we have applied Hapke's theory to retrieve the best spectral
fits to Saturn's inner regular satellites using the same methodology applied
previously for Rhea data discussed in Ciarniello et al. (2011).Comment: 44 pages, 27 figures, 7 tables. Submitted to Icaru
Active Amplification of the Terrestrial Albedo to Mitigate Climate Change: An Exploratory Study
This study explores the potential to enhance the reflectance of solar
insolation by the human settlement and grassland components of the Earth's
terrestrial surface as a climate change mitigation measure. Preliminary
estimates derived using a static radiative transfer model indicate that such
efforts could amplify the planetary albedo enough to offset the current global
annual average level of radiative forcing caused by anthropogenic greenhouse
gases by as much as 30 percent or 0.76 W/m2. Terrestrial albedo amplification
may thus extend, by about 25 years, the time available to advance the
development and use of low-emission energy conversion technologies which
ultimately remain essential to mitigate long-term climate change. However,
additional study is needed to confirm the estimates reported here and to assess
the economic and environmental impacts of active land-surface albedo
amplification as a climate change mitigation measure.Comment: 21 pages, 3 figures. In press with Mitigation and Adaptation
Strategies for Global Change, Springer, N
Evolution and Flare Activity of Delta-Sunspots in Cycle 23
The emergence and magnetic evolution of solar active regions (ARs) of
beta-gamma-delta type, which are known to be highly flare-productive, were
studied with the SOHO/MDI data in Cycle 23. We selected 31 ARs that can be
observed from their birth phase, as unbiased samples for our study. From the
analysis of the magnetic topology (twist and writhe), we obtained the following
results. i) Emerging beta-gamma-delta ARs can be classified into three
topological types as "quasi-beta", "writhed" and "top-to-top". ii) Among them,
the "writhed" and "top-to-top" types tend to show high flare activity. iii) As
the signs of twist and writhe agree with each other in most cases of the
"writhed" type (12 cases out of 13), we propose a magnetic model in which the
emerging flux regions in a beta-gamma-delta AR are not separated but united as
a single structure below the solar surface. iv) Almost all the "writhed"-type
ARs have downward knotted structures in the mid portion of the magnetic flux
tube. This, we believe, is the essential property of beta-gamma-delta ARs. v)
The flare activity of beta-gamma-delta ARs is highly correlated not only with
the sunspot area but also with the magnetic complexity. vi) We suggest that
there is a possible scaling-law between the flare index and the maximum umbral
area
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