41 research outputs found
The introduction of a new patient ‘welcome pack'
- Publication venue
- European Cystic Fibrosis Society. Published by Elsevier B.V.
- Publication date
- 30/06/2009
- Field of study
A review of techniques for parameter sensitivity analysis of environmental models
- Author
- A.M. Dunker
- B.A. Worley
- C. Cobelli
- C. Cobelli
- C. Yu
- D. Liepmann
- D. M. Hamby
- D.A. Zirnmerman
- D.D. Breshears
- D.G. Cacuci
- D.G. Cacuci
- D.J. Downing
- D.M. Hamby
- E.M. Oblow
- F.O. Hoffman
- F.W. Whicker
- F.W. Whicker
- G.E.P. Box
- G.J. Dalrymple
- J.C. Helton
- J.C. Helton
- J.C. Helton
- J.C. Helton
- J.C. Helton
- J.E. Horwedel
- J.H. Schaibly
- J.K. Summers
- J.P.C. Kleijnen
- K.A. Rose
- K.L. Reed
- L.R. Bauer
- M. Demiralp
- M. Koda
- M. Stein
- M.C.G. Hall
- M.D. McKay
- M.D. Otis
- M.E. Cunningham
- M.J. Crick
- N.D. Cox
- R. Bellman
- R.H. Gardner
- R.H. Gardner
- R.I. Cukier
- R.I. Cukier
- R.I. Cukier
- R.L. Iman
- R.L. Iman
- R.L. Iman
- R.L. Iman
- R.L. Iman
- R.L. Iman
- R.L. Iman
- R.L. Iman
- R.L. Iman
- R.L. Iman
- R.L. Iman
- R.P. Dickinson
- R.V. O'Neill
- R.W. Atherton
- S. Morisawa
- T. Margulies
- T.J. Krieger
- T.W. Kim
- W.J. Conover
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1994
- Field of study
Mathematical models are utilized to approximate various highly complex engineering, physical, environmental, social, and economic phenomena. Model parameters exerting the most influence on model results are identified through a ‘sensitivity analysis’. A comprehensive review is presented of more than a dozen sensitivity analysis methods. This review is intended for those not intimately familiar with statistics or the techniques utilized for sensitivity analysis of computer models. The most fundamental of sensitivity techniques utilizes partial differentiation whereas the simplest approach requires varying parameter values one-at-a-time. Correlation analysis is used to determine relationships between independent and dependent variables. Regression analysis provides the most comprehensive sensitivity measure and is commonly utilized to build response surfaces that approximate complex models.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/42691/1/10661_2004_Article_BF00547132.pd
Desempenho Comparativo de Seis Grupos de Cruzamento Holandês/Guzerá. 11. Peso e Altura de Vacas e Novilhas<A HREF="#back1">1</A>
- Author
- Ana Paula Madureira
- BHAT P.N.
- BHAUDARIA S.S.
- CARTWRIGHT T.C
- CUE R.I.
- DICKERSON G.E
- DICKERSON G.E
- Fernando Enrique Madalena
- FREUND R.J.
- HERD R.M
- JOANDET G.E.
- KATPATAL B.G
- KLOSTERMAN E.W.
- LEMOS A.M.
- LEMOS A.M.
- MADALENA F.E
- MADALENA F.E
- MADALENA F.E
- MADALENA F.E.
- MADUREIRA A.P
- MARSHALL T.E.
- MASON I.L.
- MCKAY R.M.
- NAMJOSHI M.
- NARAYANASWAMY M.
- NELSEN T.C.
- NICHOLSON M.J.
- PAIVA J.A.J.
- PANDA P.B.
- PANDEY H.N.
- PEROTTO D.
- Roberto Luiz Teodoro
- ROY P.K.
- RUVUNA F.
- SCHEFFÉ H
- SHARMA J.M.
- SOLÍS J.C.
- TEODORO R.L.
- THOMPSON W.R.
- VERCESI FILHO A.E.
- WINKLER R
- WINKLER R.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2002
- Field of study
The genetics of the mood disorder spectrum:genome-wide association analyses of over 185,000 cases and 439,000 controls
- Author
- Abbott Liam
- Abbott Liam
- Abdellaoui Abdel
- Abdellaoui Abdel
- Adams Mark J.
- Adams Mark J.
- Adolfsson Annelie Nordin
- Adolfsson Annelie Nordin
- Adolfsson Rolf
- Adolfsson Rolf
- Agartz Ingrid
- Agartz Ingrid
- Agerbo Esben
- Agerbo Esben
- Akil Huda
- Akil Huda
- Albani Diego
- Albani Diego
- Alda Martin
- Alda Martin
- Alliey-Rodriguez Ney
- Alliey-Rodriguez Ney
- Als Thomas D.
- Als Thomas D.
- Andlauer Till F.M.
- Andlauer Till F.M.
- Andreassen Ole A.
- Andreassen Ole A.
- Anjorin Adebayo
- Anjorin Adebayo
- Antilla Verneri
- Antilla Verneri
- Arolt Volker
- Arolt Volker
- Awasthi Swapnil
- Awasthi Swapnil
- Bacanu Silviu-Alin
- Bacanu Silviu-Alin
- Backlund Lena
- Backlund Lena
- Badner Judith A.
- Badner Judith A.
- Barchas Jack D.
- Barchas Jack D.
- Bass Nicholas
- Bass Nicholas
- Bauer Michael
- Bauer Michael
- Baune Bernhard T.
- Baune Bernhard T.
- Beekman Aartjan T.F.
- Beekman Aartjan T.F.
- Belliveau Richard
- Belliveau Richard
- Bellivier Frank
- Bellivier Frank
- Bergen Sarah E.
- Bergen Sarah E.
- Berger Klaus
- Berger Klaus
- Berrettini Wade H.
- Berrettini Wade H.
- Biernacka Joanna M.
- Biernacka Joanna M.
- Bigdeli Tim B.
- Bigdeli Tim B.
- Binder Elisabeth B.
- Binder Elisabeth B.
- Blackwood Douglas H.R.
- Blackwood Douglas H.R.
- Boehnke Michael
- Boehnke Michael
- Boks Marco
- Boks Marco
- Boocock James
- Boocock James
- Boomsma Dorret I.
- Boomsma Dorret I.
- Breen Gerome
- Bryois Julien
- Budde Monika
- Budde Monika
- Bunney William
- Bunney William
- Burmeister Margit
- Burmeister Margit
- Buttenschøn Henriette N.
- Buttenschøn Henriette N.
- Bybjerg-Grauholm Jonas
- Bybjerg-Grauholm Jonas
- Byerley William
- Byerley William
- Byrne Enda M.
- Byrne Enda M.
- Bækvad-Hansen Marie
- Bækvad-Hansen Marie
- Bøen Erlend
- Bøen Erlend
- Børglum Anders D.
- Børglum Anders D.
- Cai Na
- Cai Na
- Casas Miquel
- Casas Miquel
- Castelao Enrique
- Castelao Enrique
- Cerrato Felecia
- Cerrato Felecia
- Cervantes Pablo
- Cervantes Pablo
- Chambert Kimberly
- Chambert Kimberly
- Charney Alexander W.
- Charney Alexander W.
- Chen Danfeng
- Chen Danfeng
- Christensen Jane Hvarregaard
- Christensen Jane Hvarregaard
- Churchhouse Claire
- Churchhouse Claire
- Cichon Sven
- Cichon Sven
- Clarke Toni-Kim
- Clarke Toni-Kim
- Coleman Jonathan R.I.
- Colodro-Conde Lucía
- Colodro-Conde Lucía
- Corvin Aiden
- Corvin Aiden
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- de Geus E.J.C.
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- Derks Eske M.
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- Di Florio Arianna
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- Dolan Conor V.
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- Elvsåshagen Torbjørn
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- Escott-Price Valentina
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- Esko Tõnu
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- Fan Chun Chieh
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- Karlsson Robert
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- Kutalik Zoltán
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- Lawrence Jacob
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- Parra José Guzman
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- Pato Michele T.
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- Pedersen Marianne Giørtz
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- Pedersen Nancy L.
- Penninx Brenda W.J. H.
- Penninx Brenda W.J. H.
- Perlis Roy H.
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- Peterson Roseann E.
- Pettersson Erik
- Pettersson Erik
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- Qvist Per
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- Rice John P.
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- Rietschel Marcella
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- Rivera Margarita
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- Shen Ling
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- Shi Jianxin
- Shilling Paul D.
- Shilling Paul D.
- Shyn Stanley I.
- Shyn Stanley I.
- Sigurdsson Engilbert
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- Sobell Janet L.
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- Spijker Anne T.
- St Clair David
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- Stahl Eli A.
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- Stefansson Hreinn
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- Steffens Michael
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- Steinberg Stacy
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- Stordal Eystein
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- Strauss John S.
- Strauss John S.
- Streit Fabian
- Streit Fabian
- Strohmaier Jana
- Strohmaier Jana
- Sullivan Patrick F.
- Sullivan Patrick F.
- Szelinger Szabolcs
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- Sánchez-Mora Cristina
- Sánchez-Mora Cristina
- Tansey Katherine E.
- Tansey Katherine E.
- Teismann Henning
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- Tiemeier Henning
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- Treutlein Jens
- Treutlein Jens
- Trubetskoy Vassily
- Trubetskoy Vassily
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- Turecki Gustavo
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- Vedder Helmut
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- Wang Weiqing
- Wang Weiqing
- Wang Yunpeng
- Wang Yunpeng
- Watson Stanley J.
- Watson Stanley J.
- Webb Bradley T.
- Webb Bradley T.
- Weickert Cynthia Shannon
- Weickert Cynthia Shannon
- Weickert Thomas W.
- Weickert Thomas W.
- Weinsheimer Shantel Marie
- Weinsheimer Shantel Marie
- Weissman Myrna M.
- Weissman Myrna M.
- Wellmann Jürgen
- Wellmann Jürgen
- Werge Thomas
- Werge Thomas
- Whitehead Pavlides Jennifer M.
- Whitehead Pavlides Jennifer M.
- Willemsen Gonneke
- Willemsen Gonneke
- Witt Stephanie H.
- Witt Stephanie H.
- Wray Naomi R.
- Wray Naomi R.
- Wu Yang
- Wu Yang
- Xi Hualin S.
- Xi Hualin S.
- Xu Wei
- Xu Wei
- Yang Jian
- Yang Jian
- Young Allan H.
- Young Allan H.
- Zandi Peter
- Zandi Peter
- Zhang Futao
- Zhang Futao
- Zhang Peng
- Zhang Peng
- Zollner Sebastian
- Zollner Sebastian
- Ösby Urban
- Ösby Urban
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/11/2019
- Field of study
Background
Mood disorders (including major depressive disorder and bipolar disorder) affect 10-20% of the population. They range from brief, mild episodes to severe, incapacitating conditions that markedly impact lives. Despite their diagnostic distinction, multiple approaches have shown considerable sharing of risk factors across the mood disorders.
Methods
To clarify their shared molecular genetic basis, and to highlight disorder-specific associations, we meta-analysed data from the latest Psychiatric Genomics Consortium (PGC) genome-wide association studies of major depression (including data from 23andMe) and bipolar disorder, and an additional major depressive disorder cohort from UK Biobank (total: 185,285 cases, 439,741 controls; non-overlapping N = 609,424).
Results
Seventy-three loci reached genome-wide significance in the meta-analysis, including 15 that are novel for mood disorders. More genome-wide significant loci from the PGC analysis of major depression than bipolar disorder reached genome-wide significance. Genetic correlations revealed that type 2 bipolar disorder correlates strongly with recurrent and single episode major depressive disorder. Systems biology analyses highlight both similarities and differences between the mood disorders, particularly in the mouse brain cell-types implicated by the expression patterns of associated genes. The mood disorders also differ in their genetic correlation with educational attainment – positive in bipolar disorder but negative in major depressive disorder.
Conclusions
The mood disorders share several genetic associations, and can be combined effectively to increase variant discovery. However, we demonstrate several differences between these disorders. Analysing subtypes of major depressive disorder and bipolar disorder provides evidence for a genetic mood disorders spectrum
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
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- Šantak G.
- Šimko K.
- Žatecký J.
- Publication venue
- Oxford University Press (OUP)
- Publication date
- 01/07/2023
- Field of study
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Mudança organizacional: uma abordagem preliminar
- Author
- 0'TOOLE James
- 0LSON Philip D
- 0UCHI William
- 1SABELLA L.A
- ABRAHAMSON E
- ACAR W
- ACHROL R.S
- ADIZES lchak
- ANDERSON D.L.
- ARAUJO Luis Cesar G. de
- ARAUJO Luis Cesar Gon lves de
- ARCHIER Georges
- ARGYRIS Chris
- ARONOFF C.E
- BAKOS S.C
- BARDWICK J.M
- BARTUNEK J.N
- BASIL Douglas Constantine
- BENNIS Warren G.
- BERMAN Marshall
- BERTRAND Kate
- BETZ T.G.
- BICE M
- BICE M
- BRAMSON R.A
- BRATKOVICH J.R
- BROWN J.S.
- BROWN R
- BRYAN J.E.
- BURNS Tom
- BUSH JR. J. B
- BYRD Richard E
- CALISH lrwing G
- CALORI R
- CARAVANTES Geraldo Ronchetti
- CARLTON M.R
- CARR C.D
- CHADWICK S.
- CHAISTIANS lan
- CHORN N.H.
- COHN Steven F
- COLE R.L.
- CONNOR P.E
- CORBITT G. F.
- COYLE J
- CULLEN John B
- CUMMINGS T.G
- CZARNECKI Gerald W
- DAILEY R.C
- DALZIEL Murray M
- DAMANPOUR F
- DAMANPOUR F
- DANIELSON Christer
- DAVIDSON K.M
- DAVIS S.M
- DE CHAMBEAU F.A
- DEAL Terence
- DEEPROSE D
- DeLISI P.S
- DENOVA C.C
- DERVEN M.G
- DONNELLON Anne
- DRAZIN R
- DREILINGER C
- DRUCKER Peter F
- DRUCKER Peter F
- DUMAINE Brian
- DUPUY J
- DYER William G
- ELLIOTI Ronald D
- ENGELBART D
- FARQUHAR C.R
- FARRELL L
- FELDENKIRCHEN Wilfried
- FITZGERALD J
- FITZGERALD T.H
- FLAMHOLTZ E
- FLETT F
- FONVIELLE William
- FOSTER Lawrence W
- FREITAS Maria Ester de
- FRIEDMAN S.D.
- FRITZ Norma R
- FROHMAN M
- FROHMAN M
- FROST Peter J
- GARCIA R.M
- GARCIA R.M
- GARCIA Ramon Moreira
- GIBSON J.l.
- GINSBERG A
- GIOIA D.A.
- GMELCH W.H.
- GOLEMBIEWSKI R.T
- GORDON G.G
- GOURVISH T.R
- GRANDORI A
- GREEINER L.E
- GREEN A
- GRIMM C.M.
- GRINYER P
- GROSSMAN Lee
- HAGGERTY A.G
- HALL J
- HALL L
- HANDY Charles
- HARARI 0
- HARARI 0
- HARRISON J. Richard
- HARRISON M.l
- HARRISON M.l
- HAUGH J.W
- HELFGOTI Roy B
- HENRICI S.B
- HERRINGTON G.M
- HERSEY Paul
- HERZBERG F
- HERZOG J.P
- HOLT J
- HORNSTEIN Harvey A
- HORTON T.R
- HORTON T.R
- HORTON Thomas R
- HOUNSHELL David A
- HOUSTON P
- HUEY J
- JACOBS D
- JAQUES Elliott
- JOHNSON J.D.
- JOHNSON Michael
- JONES Christopher G
- KANTER Rosabeth Moss
- KANTER Rosabeth Moss
- KANTER Rosabeth Moss
- KAZEMEK E.A.
- KAZEMEK Edward A
- KELLY D
- KETS DE VRIES Manfred F.R
- KIEL L. Douglas
- KILMANN R.H
- KILMANN R.H.
- KILMANN Ralph H
- KILMANN Ralph H
- KIMBERLY J.R
- KING Bob
- KING R.P.
- KIRKLAND R.I.
- KNIGHT K
- KOCH Donald L.
- KOTIER John P
- KOTLER Philip
- KRAM K.E.
- KUHN Robert Lawrence
- KUHN Thomas S
- LAND George
- LAURIE J
- LEHRER Robert N
- LINDER JaneC
- LIPPITI Gordon L
- LIPPITT Gordon
- LORD V
- MACCOBY M
- MACLAGAN Patrick W
- MACLEOD J.S.
- MAISEL L.S
- MALEKZADEH A.R
- MANN R.W
- MARCH JamesG
- MARGERISON C
- MARTIN D
- MASTENBROEK W.F.G
- MASTENBROEK W.F.G.
- McDONNELL E.D.
- McKAY Noble
- McKENDRICK J.E
- McQUADE H.A.
- MEARES Larry B
- MILLER J.T.
- MILLER S.G.
- MILLS D. Quinn
- MIRONOFF A
- MIRVIS Philip H
- MISAWA Mitsuru
- MOODY M.H
- MORAN Robert T
- MORGAN Gareth
- MORGAN John S
- MOURA Paulo Cavalcanti da Costa
- NADLER D.A.
- NAISBITI John
- NAISBITT John
- NAISBITT John
- NEIMAN A.A.
- NELSON Reed E
- NEWMAN G
- NICHOLAS John M
- NODELL R.S
- OVELLETTE L.P
- PARKER D
- PASCALE R.T
- PAYNE T
- PEREIRA Maria Jose L. Bretas
- PETERS T
- PETERS Tom
- PETERS Tom
- POLLERT Anna
- POLLOCK T
- PONDY L.R
- POWER B.L
- PRENTICE G
- PRIGOGINE llya
- RAMOS Alberto Guerreiro
- RANDOLPH W.A.
- RAUDSEPP E
- RICE A.K.
- ROSS G.H.B.
- ROTHWELL William J
- RUBIN I
- SAKAI Kun asu
- SANDY W
- SANDY W
- SANDY W
- SCHAEFFER D
- SCHEIN Edgar H
- SCHONBERGER Richard J
- SCHRAGE M
- SCHULER R.S.
- SCHUSTER M
- SCHWASS G.L
- SCOTT S
- SEMLER Ricardo
- SHERIDAN J.H
- SHERMAN C.F.
- SINK D Scott
- SPARKS R
- STEELE B
- STEVENS C.A.
- SULLIVAN J.J
- TAFT Susan Hoefflir
- THOMAS John M
- Thomaz Wood Jr
- THORNE P
- THORNE P
- TOFFLER Alvin
- TOWSEND Robert
- UTTERBACK J.M
- VAN DER ERVE M
- VASCONCELLOS Joao Gualberto Moreira
- VICKERY H.B
- VOZIKIS George S
- WALKER J.P.
- WANT J.H
- WARD K
- WATERMAN JR Robert H
- WATERMAN JR Robert H
- WEBER K.F.
- WELCH Jonathan B
- WERNER M
- WILLIAMS M.M
- WILSON Ira G
- WILSON l
- WRIGHT P.C
- YORKS Lyle
- ZMUD Robert W
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Effect of Dietary Fiber on Growth Rate and Intestinal Measurements
- Author
- Publication venue
- Hosted by Utah State University Libraries
- Publication date
- 01/01/1980
- Field of study
Implicit Fitness Sharing Speciation and Emergent Diversity in Tree Classifier Ensembles
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2004
- Field of study