\epsilon-regularity for systems involving non-local, antisymmetric operators

We prove an epsilon-regularity theorem for critical and super-critical systems with a non-local antisymmetric operator on the right-hand side. These systems contain as special cases, Euler-Lagrange equations of conformally invariant variational functionals as Rivi\`ere treated them, and also Euler-Lagrange equations of fractional harmonic maps introduced by Da Lio-Rivi\`ere. In particular, the arguments presented here give new and uniform proofs of the regularity results by Rivi\`ere, Rivi\`ere-Struwe, Da-Lio-Rivi\`ere, and also the integrability results by Sharp-Topping and Sharp, not discriminating between the classical local, and the non-local situations

Toll-like receptor-4 signaling pathway in aorta aging and diseases: "its double nature"

Recent advances in the field of innate immunity have revealed a complex role of innate immune signaling pathways in both tissue homeostasis and disease. Among them, the Toll-like receptor 4 (TLR-4) pathways has been linked to various pathophysiological conditions, such as cardiovascular diseases (CVDs). This has been interrogated by developing multiple laboratory tools that have shown in animal models and clinical conditions, the involvement of the TLR-4 signaling pathway in the pathophysiology of different CVDs, such as atherosclerosis, ischemic heart disease, heart failure, ischemia-reperfusion injury and aorta aneurysm. Among these, aorta aneurysm, a very complex pathological condition with uncertain etiology and fatal complications (i.e. dissection and rupture), has been associated with the occurrence of high risk cardiovascular conditions, including thrombosis and embolism. In this review, we discuss the possible role of TLR-4signaling pathway in the development of aorta aneurysm, considering the emerging evidence from ongoing investigations. Our message is that emphasizing the role of TLR-4signaling pathway in aorta aneurysm may serve as a starting point for future studies, leading to a better understanding of the pathophysiological basis and perhaps the effective treatment of this difficult human disease

Health management in aquaculture

A textbook on diseases of cultured warmwater fish and shrimps in the Philippines. Eleven chapters cover essential information on the basic principles of disease causation, major diseases of cultured fish and crustaceans, particularly shrimps, and methods of prevention and control. Emphasis is made on major diseases that occur in the Philippines and other countries in the Asian region. Included also are topics on harmful algae, immunology and molecular biological diagnostic techniques.1st Ed

Agent architecture for adaptive behaviours in autonomous driving

Evolution has endowed animals with outstanding adaptive behaviours which are grounded in the organization of their sensorimotor system. This paper uses inspiration from these principles of organization in the design of an artificial agent for autonomous driving. After distilling the relevant principles from biology, their functional role in the implementation of an artificial system are explained. The resulting Agent, developed in an EU H2020 Research and Innovation Action, is used to concretely demonstrate the emergence of adaptive behaviour with a significant level of autonomy. Guidelines to adapt the same principled organization of the sensorimotor system to other agents for driving are also obtained. The demonstration of the system abilities is given with example scenarios and open access simulation tools. Prospective developments concerning learning via mental imagery are finally discussed

Analisis Sentimen terhadap Tempat Wisata dari Komentar Pengunjung dengan Menggunakan Metode Naïve Bayes Classifier Studi Kasus Jawa Barat

Penelitian ini dilakukan untuk memberikan informasi tentang kualitas sebuah tempat wisata yang ada di Jawa Barat. Dengan menggunakan sentimen dari pengunjung, Dinas Pariwisata dan Kebudayaan Provinsi Jawa Barat dapat menentukan langkah apa yang harus diambil untuk memutuskan langkah apa yang harus diambil tanpa harus turun langsung dan melihat satu – persatu. Dengan menggunakan Google Maps sebagai sumber data dalam pembuatan aplikasi, data yang digunakan dalam pembuatan sistem ini yaitu data tempat wisata, sentimen pengunjung dan rating tempat

Debris Impact Detection Instrument for Crewed Modules

When micrometeoroid or debris impacts occur on a space habitat, crew members need to be quickly informed of the likely extent of damage, and be directed to the impact location for possible repairs. This is especially important because the outer walls of pressurized volumes are often not easily accessible, blocked by racks or cabinets. The goal of the Habitat Particle Impact Monitoring System (HIMS) is to develop a fully automated, end-to-end particle impact detection system for crewed space exploration modules. The HIMS uses multiple passive, thin film piezo-polymer vibration sensors to detect impacts on a surface, and computer processing of the acoustical signals to characterize the impacts. Development and demonstration of the HIMS is proceeding in concert with NASA's Habitat Demonstration Unit (HDU) Project. The HDU Project is designed to develop and test various technologies, configurations, and operational concepts for exploration habitats. This paper describes the HIMS development, initial testing, and HDU integration efforts. Initial tests of the system on the HDU were conducted at NASA s 2010 and 2011 Desert Research and Technologies Studies (Desert-RATS or D-RATS). The HDU lab module, as seen from above, has an open circular floorplan divided into eight wedge-shaped Segments. The side wall of the module -- the surface used for this technology demonstration -- is a hard fiberglass composite covered with a layer of sprayed-on foam insulation. Four sensor locations were assigned near the corners of a rectangular pattern on the wall of one segment of the HDU lab module. The flat, self-adhesive sensors were applied to the module during its initial outfitting. To study the influence of the wall s construction (thickness and materials), three sets of four sensors were installed at different layer depths: on the interior of the module s wall, on the exterior of the same wall, and on the exterior of the foam insulation. The signal produced when a vibration passes through a sensor is first sent through a pre-amplifier. The amplified signal then is sent to the data acquisition and data processing systems. The vibration data from the sensors are then processed and reduced to a form suitable for presentation to the crew

The oxygen uptake slow component at submaximal intensities in breaststroke swimming

The present work proposed to study the oxygen uptake slow component (VO2 SC) of breaststroke swimmers at four different intensities of submaximal exercise, via mathematical modeling of a multi-exponential function. The slow component (SC) was also assessed with two different fixed interval methods and the three methods were compared. Twelve male swimmers performed a test comprising four submaximal 300 m bouts at different intensities where all expired gases were collected breath by breath. Multi-exponential modeling showed values above 450 ml·min-1 of the SC in the two last bouts of exercise (those with intensities above the lactate threshold). A significant effect of the method that was used to calculate the VO2 SC was revealed. Higher mean values were observed when using mathematical modeling compared with the fixed interval 3rd min method (F=7.111; p=0.012; η2=0.587); furthermore, differences were detected among the two fixed interval methods. No significant relationship was found between the SC determined by any method and the blood lactate measured at each of the four exercise intensities. In addition, no significant association between the SC and peak oxygen uptake was found. It was concluded that in trained breaststroke swimmers, the presence of the VO2 SC may be observed at intensities above that corresponding to the 3.5 mM-1 threshold. Moreover, mathematical modeling of the oxygen uptake on-kinetics tended to show a higher slow component as compared to fixed interval methods.info:eu-repo/semantics/publishedVersio

The value function of an asymptotic exit-time optimal control problem

We consider a class of exit--time control problems for nonlinear systems with a nonnegative vanishing Lagrangian. In general, the associated PDE may have multiple solutions, and known regularity and stability properties do not hold. In this paper we obtain such properties and a uniqueness result under some explicit sufficient conditions. We briefly investigate also the infinite horizon problem

MotifScorer: using a compendium of microarrays to identify regulatory motifs

We describe MotifScorer, a program for systematic genome-wide identification of transcription sites. The program uses a compendium of gene expression microarrays and implements state-of-art partial least squares (PLSs) based regression and stepwise regression procedures. Candidate motifs from the upstream sequences of groups of co-regulated genes are identified and assigned a score using genomic background models and available motif finding tools. The use of a large library of expression data allows statistical comparative analysis of the specificity of motifs identified in different conditions

An Optimal Execution Problem with Market Impact

We study an optimal execution problem in a continuous-time market model that considers market impact. We formulate the problem as a stochastic control problem and investigate properties of the corresponding value function. We find that right-continuity at the time origin is associated with the strength of market impact for large sales, otherwise the value function is continuous. Moreover, we show the semi-group property (Bellman principle) and characterise the value function as a viscosity solution of the corresponding Hamilton-Jacobi-Bellman equation. We introduce some examples where the forms of the optimal strategies change completely, depending on the amount of the trader's security holdings and where optimal strategies in the Black-Scholes type market with nonlinear market impact are not block liquidation but gradual liquidation, even when the trader is risk-neutral.Comment: 36 pages, 8 figures, a modified version of the article "An optimal execution problem with market impact" in Finance and Stochastics (2014